| Compound ID |
Compound Name |
Compound Formula |
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
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|
C5H9N3
|
4
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
| 3 |
Ki = 11.75 nM
|
|
|
| 4 |
Ki = 588.84 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
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|
C15H24N4S
|
7
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
| 3 |
IC50 = 517.5 nM
|
|
|
| 4 |
Ki = 29.51 nM
|
|
|
| 5 |
Ki = 52.48 nM
|
|
|
| 6 |
Ki = 60 nM
|
|
|
| 7 |
Ki = 70.79 nM
|
|
|
|
CP0762913
|
4-(3-Hexyloxy-propyl)-1H-imidazole; compound with (Z)-but-2-enedioic acid
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|
C16H26N2O5
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0205835
|
1-[5-(4-chlorophenoxy)pentyl]-3-methylpiperidine;oxalic acid
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|
C19H28ClNO5
|
2
|
| 1 |
EC50 = 72 nM
|
|
|
| 2 |
Ki = 133 nM
|
|
|
|
CP0133780
|
1-[7-(4-chlorophenoxy)heptyl]piperidine;oxalic acid
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|
C20H30ClNO5
|
2
|
| 1 |
EC50 = 75 nM
|
|
|
| 2 |
Ki = 128 nM
|
|
|
|
CP0801074
|
4-(3-Pentyloxy-propyl)-1H-imidazole; compound with (Z)-but-2-enedioic acid
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|
C15H24N2O5
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0801169
|
4-(3-Prop-2-ynyloxy-propyl)-1H-imidazole oxalic acid
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|
C11H14N2O5
|
1
|
| 1 |
EC50 = 135 nM
|
|
|
|
CP0849831
|
1-(5-(4-(tert-Pentyl)phenoxy)pentyl)piperidine hydrogen oxalate
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|
C23H37NO5
|
1
|
| 1 |
EC50 = 157 nM
|
|
|
|
CP0227869
|
3-methyl-1-[5-[4-(2-methylbutan-2-yl)phenoxy]pentyl]piperidine;oxalic acid
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|
C24H39NO5
|
1
|
| 1 |
EC50 = 164 nM
|
|
|
|
CP0469142
|
4-(cyclohexylmethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
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|
C14H21N5
|
2
|
| 1 |
EC50 = 251.19 nM
|
|
|
| 2 |
Ki = 75.86 nM
|
|
|
|
CP0806435
|
4-(3-Butoxy-propyl)-1H-imidazole; compound with (Z)-but-2-enedioic acid
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|
C14H22N2O5
|
1
|
| 1 |
EC50 = 311 nM
|
|
|
|
CP0837331
|
4-(3-Allyloxy-propyl)-1H-imidazole oxalic acid
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|
C11H16N2O5
|
1
|
| 1 |
EC50 = 366 nM
|
|
|
|
CP0406979
|
1-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(thiophen-2-ylmethyl)urea
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|
C21H28N4OS
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0489114
|
1-cyclohexyl-3-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C22H34N4O
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0374981
|
1-[(3,5-dichlorophenyl)methyl]-3-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C23H28Cl2N4O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0375427
|
1-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(thiophen-2-ylmethyl)urea
Show/Hide
|
C22H30N4OS
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0380117
|
1-(3,5-dichloro-4-methylphenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
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|
C22H27Cl2N3O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0380997
|
4-methyl-N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperazine-1-carboxamide
Show/Hide
|
C21H33N5O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0380999
|
1-cyclohexyl-3-[2-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C23H36N4O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0456099
|
1-cyclohexyl-3-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C23H36N4O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0567287
|
N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperidine-1-carboxamide
Show/Hide
|
C21H32N4O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0500862
|
N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-4-phenylpiperazine-1-carboxamide
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|
C26H35N5O
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0315593
|
1-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3-methoxypyridin-4-one
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.46 nM
|
|
|
|
CP0380162
|
1-(2,4-difluorophenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
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|
C21H25F2N3O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0406980
|
4-acetyl-N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperazine-1-carboxamide
Show/Hide
|
C22H33N5O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0406982
|
1-(3,5-dichlorophenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
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|
C21H25Cl2N3O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0315602
|
3-methoxy-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
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|
C19H24N2O3
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0406981
|
1-[4-[2-(diethylamino)ethoxy]phenyl]-3-[4-(2-methylpropoxy)phenyl]thiourea
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|
C23H33N3O2S
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0524039
|
1-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(4-phenoxyphenyl)urea
Show/Hide
|
C29H34N4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0469817
|
ethyl 2-[[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]methoxy]acetate
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|
C24H31NO3
|
1
|
| 1 |
IC50 = 0.67 nM
|
|
|
|
CP0918063
|
1-(4-chlorophenyl)-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)urea
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|
C21H26ClN3O2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0143835
|
1-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methoxypyridin-4-one
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|
C21H26N2O3
|
1
|
| 1 |
IC50 = 0.74 nM
|
|
|
|
CP0960309
|
(R)-5-((4'-(2-(2-methylpyrrolidin-1-yl)ethyl)biphenyl-4-yl)methyl)-1H-tetrazole
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|
C21H25N5
|
1
|
| 1 |
IC50 = 0.78 nM
|
|
|
|
CP0576431
|
US9365511, 18
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|
C25H32N2O3
|
1
|
| 1 |
IC50 = 0.79 nM
|
|
|
|
CP0489113
|
4-methyl-N-[2-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperazine-1-carboxamide
Show/Hide
|
C22H35N5O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0085869
|
1-(3,5-dichlorophenyl)-3-[2-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C23H28Cl2N4O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0530443
|
1-[2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]ethyl]tetrazole
Show/Hide
|
C22H27N5
|
1
|
| 1 |
IC50 = 0.93 nM
|
|
|
|
CP0573394
|
tert-butyl 2,2-dimethyl-3-[2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]ethylamino]-3-oxopropanoate
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|
C30H42N2O3
|
1
|
| 1 |
IC50 = 0.95 nM
|
|
|
|
CP0561581
|
US9365511, 12
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|
C30H42N2O3
|
1
|
| 1 |
IC50 = 0.95 nM
|
|
|
|
CP0576432
|
US9365511, 35
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|
C30H40N2O3
|
1
|
| 1 |
IC50 = 0.96 nM
|
|
|
|
CP0483318
|
4-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]butanoic acid
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|
C23H29NO2
|
1
|
| 1 |
IC50 = 0.97 nM
|
|
|
|
CP0566654
|
methyl 3-[2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]ethylamino]-3-oxopropanoate
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
IC50 = 0.99 nM
|
|
|
|
CP0574093
|
US9365511, 24
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|
C25H32N2O3
|
1
|
| 1 |
IC50 = 0.99 nM
|
|
|
|
CP0955902
|
1-(2,6-dichlorophenyl)-3-(4-(2-(diethylamino)ethoxy)phenyl)urea
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|
C19H23Cl2N3O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0374980
|
3-[acetyl(methyl)amino]-N-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C24H37N5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0403914
|
4-methyl-N-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperazine-1-carboxamide
Show/Hide
|
C22H35N5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0456097
|
1-[(3,5-dichlorophenyl)methyl]-3-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C24H30Cl2N4O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0456098
|
3-[acetyl(methyl)amino]-N-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]pyrrolidine-1-carboxamide
Show/Hide
|
C23H35N5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0463172
|
methyl 3-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]propanoate
Show/Hide
|
C23H29NO2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0315597
|
2-ethyl-3-methoxy-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
IC50 = 1.11 nM
|
|
|
|
CP0041493
|
Clobenpropit
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|
C14H17ClN4S
|
4
|
| 1 |
IC50 = 1.15 nM
|
|
|
| 2 |
Ki = 0.5012 nM
|
|
|
| 3 |
Ki = 2.4 nM
|
|
|
| 4 |
Ki = 2.818 nM
|
|
|
|
CP0248952
|
1-(3,5-dichlorophenyl)-3-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C22H26Cl2N4O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0481578
|
2-[2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]ethyl]tetrazole
Show/Hide
|
C22H27N5
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0566653
|
methyl 2,2-dimethyl-3-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]anilino]-3-oxopropanoate
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0576433
|
US9365511, 38
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0257424
|
1-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
IC50 = 1.39 nM
|
|
|
|
CP0380163
|
1-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(4-phenoxyphenyl)urea
Show/Hide
|
C28H32N4O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0574092
|
US9365511, 16
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|
C30H40N2O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0258440
|
3-methoxy-1-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]pyridin-4-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 1.67 nM
|
|
|
|
CP0449651
|
ethyl 3-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]propanoate
Show/Hide
|
C24H31NO2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0449650
|
methyl 3-[[1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]cyclopentyl]amino]-3-oxopropanoate
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|
C28H36N2O3
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0483317
|
US9365511, 27
Show/Hide
|
C28H36N2O3
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0229942
|
5-methoxy-2-methyl-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 1.94 nM
|
|
|
|
CP0463165
|
tert-butyl (2S)-2-methyl-3-[2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]ethylamino]-3-oxopropanoate
Show/Hide
|
C29H40N2O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0573393
|
5-[[1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]cyclopentyl]amino]-5-oxopentanoic acid
Show/Hide
|
C29H38N2O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0516376
|
US9365511, 33
Show/Hide
|
C29H38N2O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0560414
|
US9365511, 13
Show/Hide
|
C29H40N2O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0456100
|
4-acetyl-N-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]piperazine-1-carboxamide
Show/Hide
|
C23H35N5O2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0471630
|
1-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
IC50 = 2.43 nM
|
|
|
|
CP0460334
|
3-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]propanoic acid
Show/Hide
|
C22H27NO2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0573392
|
4-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]anilino]-4-oxobutanoic acid
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0574094
|
US9365511, 43
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0554163
|
US9365511, 20
Show/Hide
|
C34H46N2O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0456096
|
1-(3,5-dichlorophenyl)-3-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea
Show/Hide
|
C23H28Cl2N4O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0463166
|
2-methyl-2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]propanoic acid
Show/Hide
|
C23H29NO2
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0398129
|
methyl 1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]cyclopentane-1-carboxylate
Show/Hide
|
C26H33NO2
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0460336
|
4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzoic acid
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0515002
|
US9365511, 26
Show/Hide
|
C28H38N2O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0259576
|
oxalic acid;1-[5-(4-phenylphenoxy)pentyl]piperidine
Show/Hide
|
C24H31NO5
|
2
|
| 1 |
IC50 = 4.04 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0258442
|
3-methoxy-2-methyl-1-[4-(4-pyrrolidin-1-ylbutoxy)phenyl]pyridin-4-one
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
IC50 = 4.33 nM
|
|
|
|
CP0460333
|
2-[[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]methoxy]acetic acid
Show/Hide
|
C22H27NO3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0315596
|
3-methoxy-2-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
IC50 = 5.82 nM
|
|
|
|
CP0848336
|
1,3-bis(4-(2-(dimethylamino)ethyl)phenyl)urea
Show/Hide
|
C21H30N4O
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0358012
|
3-methoxy-2-methyl-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 6.53 nM
|
|
|
|
CP0960310
|
US9365511, 44
Show/Hide
|
C22H27N5
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0856437
|
1-(4-(3-(diethylamino)propoxy)phenyl)-3-(2,4-difluorophenyl)urea
Show/Hide
|
C20H25F2N3O2
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0358011
|
3-ethoxy-2-methyl-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
IC50 = 7.97 nM
|
|
|
|
CP0460335
|
2-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]acetic acid
Show/Hide
|
C21H25NO2
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0487533
|
3-methoxy-2-methyl-1-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]pyridin-4-one
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
IC50 = 8.92 nM
|
|
|
|
CP0343761
|
oxalic acid;1-[5-(4-phenylphenoxy)pentyl]azepane
Show/Hide
|
C25H33NO5
|
2
|
| 1 |
IC50 = 9.08 nM
|
|
|
| 2 |
Ki = 34 nM
|
|
|
|
CP0848362
|
1-(4-(2-(diethylamino)ethoxy)phenyl)-3-(2-ethoxy-5-methylphenyl)urea
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0857636
|
1-(4-(3-(dimethylamino)propoxy)phenyl)-3-(2,3-dimethylphenyl)urea
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
IC50 = 14.7 nM
|
|
|
|
CP0398130
|
methyl 5-[[1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]cyclopentyl]amino]-5-oxopentanoate
Show/Hide
|
C30H40N2O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0861347
|
1-(4-chlorophenyl)-3-(4-(2-(dimethylamino)ethoxy)phenyl)urea
Show/Hide
|
C17H20ClN3O2
|
1
|
| 1 |
IC50 = 16.4 nM
|
|
|
|
CP0229943
|
1-[4-(4-cyclopentylpiperazin-1-yl)sulfonylphenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C22H29N3O4S
|
1
|
| 1 |
IC50 = 22.11 nM
|
|
|
|
CP0912817
|
1-(4-chlorophenyl)-3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C20H24ClN3O2
|
1
|
| 1 |
IC50 = 27.5 nM
|
|
|
|
CP0549429
|
1-[4-(4-cyclobutylpiperazin-1-yl)sulfonylphenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C21H27N3O4S
|
1
|
| 1 |
IC50 = 35.81 nM
|
|
|
|
CP0861345
|
1-(2,4-dichlorophenyl)-3-(4-(2-(diethylamino)ethoxy)phenyl)urea
Show/Hide
|
C19H23Cl2N3O2
|
1
|
| 1 |
IC50 = 39.1 nM
|
|
|
|
CP0947503
|
1-(2,4-difluorophenyl)-3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C20H23F2N3O2
|
1
|
| 1 |
IC50 = 40.5 nM
|
|
|
|
CP0397516
|
N-[2-(1H-indol-3-yl)ethyl]-4-(morpholin-4-ylmethyl)aniline
Show/Hide
|
C21H25N3O
|
2
|
| 1 |
IC50 = 49 nM
|
|
|
| 2 |
Ki = 4.26 nM
|
|
|
|
CP0315595
|
1-[4-(4-cyclopentylpiperazine-1-carbonyl)phenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C23H29N3O3
|
1
|
| 1 |
IC50 = 49.04 nM
|
|
|
|
CP0864064
|
Evotec
Show/Hide
|
C18H26N4O2
|
1
|
| 1 |
IC50 <= 50 nM
|
|
|
|
CP0308883
|
3-N-[2-[4-(piperidin-1-ylmethyl)phenoxy]ethyl]quinoxaline-2,3-diamine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
IC50 = 52.4 nM
|
|
|
|
CP0535182
|
1-[4-(4-cyclobutylpiperazine-1-carbonyl)phenyl]-3-methoxy-2-methylpyridin-4-one
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 = 68.3 nM
|
|
|
|
CP0891572
|
1-(4-(2-(dimethylamino)ethoxy)phenyl)-3-(2,3-dimethylphenyl)urea
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
IC50 = 73.1 nM
|
|
|
|
CP0397640
|
N-[2-(1H-indol-3-yl)ethyl]-4-(piperidin-1-ylmethyl)aniline
Show/Hide
|
C22H27N3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0555528
|
3-methoxy-2-methyl-1-[4-(3-morpholin-4-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C20H26N2O4
|
1
|
| 1 |
IC50 = 107.8 nM
|
|
|
|
CP0857676
|
1-(4-(2-(diethylamino)ethoxy)phenyl)-3-(2,4-difluorophenyl)urea
Show/Hide
|
C19H23F2N3O2
|
1
|
| 1 |
IC50 = 111.4 nM
|
|
|
|
CP0274671
|
3-[[4-(piperidin-1-ylmethyl)anilino]methyl]quinoxalin-2-amine
Show/Hide
|
C21H25N5
|
1
|
| 1 |
IC50 = 129.7 nM
|
|
|
|
CP0861346
|
1-(2,4-difluorophenyl)-3-(4-(2-(dimethylamino)ethoxy)phenyl)urea
Show/Hide
|
C17H19F2N3O2
|
1
|
| 1 |
IC50 = 148.6 nM
|
|
|
|
CP0331699
|
1-(5-naphthalen-1-yloxypentyl)piperidine
Show/Hide
|
C20H27NO
|
2
|
| 1 |
IC50 = 165 nM
|
|
|
| 2 |
Ki = 53.9 nM
|
|
|
|
CP0257423
|
3-methoxy-2-methyl-1-[4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]pyridin-4-one
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
IC50 = 167.4 nM
|
|
|
|
CP0761405
|
N-(3-aminoquinoxalin-2-yl)-4-(piperidin-1-ylmethyl)benzamide hydrochloride
Show/Hide
|
C21H24ClN5O
|
2
|
| 1 |
IC50 = 170.6 nM
|
|
|
| 2 |
IC50 = 511 nM
|
|
|
|
CP0489743
|
N-[2-(1H-indol-3-yl)ethyl]-4-(pyrrolidin-1-ylmethyl)aniline
Show/Hide
|
C21H25N3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0338442
|
3-N-[2-[4-(diethylaminomethyl)phenoxy]ethyl]quinoxaline-2,3-diamine
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
IC50 = 182 nM
|
|
|
|
CP0338441
|
N-(3-aminoquinoxalin-2-yl)-4-(piperidin-1-ylmethyl)benzamide
Show/Hide
|
C21H23N5O
|
2
|
| 1 |
IC50 = 189.3 nM
|
|
|
| 2 |
IC50 = 280 nM
|
|
|
|
CP0152143
|
3-amino-N-[4-(pyrrolidin-1-ylmethyl)phenyl]quinoxaline-2-carboxamide
Show/Hide
|
C20H21N5O
|
2
|
| 1 |
IC50 = 260 nM
|
|
|
| 2 |
IC50 = 378.5 nM
|
|
|
|
CP0404082
|
4-(diethylaminomethyl)-N-[2-(1H-indol-3-yl)ethyl]aniline
Show/Hide
|
C21H27N3
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0390184
|
1-(5-naphthalen-1-yloxypentyl)azepane
Show/Hide
|
C21H29NO
|
2
|
| 1 |
IC50 = 312 nM
|
|
|
| 2 |
Ki = 21.9 nM
|
|
|
|
CP0487534
|
3-methoxy-2-methyl-1-[4-(4-propan-2-ylpiperazine-1-carbonyl)phenyl]pyridin-4-one
Show/Hide
|
C21H27N3O3
|
1
|
| 1 |
IC50 = 350.5 nM
|
|
|
|
CP0257422
|
3-methoxy-2-methyl-1-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]pyridin-4-one
Show/Hide
|
C20H27N3O4S
|
1
|
| 1 |
IC50 = 385.3 nM
|
|
|
|
CP0521306
|
N-[3-(1H-indol-3-yl)propyl]-4-(morpholin-4-ylmethyl)aniline
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0397519
|
N-(1H-indol-3-ylmethyl)-4-(piperidin-1-ylmethyl)aniline
Show/Hide
|
C21H25N3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0397517
|
[4-(morpholin-4-ylmethyl)phenyl] 2-(1H-indol-3-yl)acetate
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0404081
|
[4-(piperidin-1-ylmethyl)phenyl] 2-(1H-indol-3-yl)acetate
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
IC50 = 1040 nM
|
|
|
|
CP0508551
|
N-[4-(piperidin-1-ylmethyl)phenyl]-1H-indole-3-carboxamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 = 1210 nM
|
|
|
|
CP0572599
|
2-(1H-indol-3-yl)-N-[4-(pyrrolidin-1-ylmethyl)phenyl]acetamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 = 1370 nM
|
|
|
|
CP0487531
|
3-methoxy-2-methyl-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyridin-4-one
Show/Hide
|
C19H24N2O3
|
1
|
| 1 |
IC50 = 1787.1 nM
|
|
|
|
CP0525649
|
[4-(piperidin-1-ylmethyl)phenyl] 1H-indole-3-carboxylate
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
|
CP0404083
|
2-(1H-indol-3-yl)-N-[4-(morpholin-4-ylmethyl)phenyl]acetamide
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
IC50 = 2190 nM
|
|
|
|
CP0493015
|
[4-(pyrrolidin-1-ylmethyl)phenyl] 2-(1H-indol-3-yl)acetate
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
IC50 = 2460 nM
|
|
|
|
CP0404080
|
2-(1H-indol-3-yl)-N-[4-(piperidin-1-ylmethyl)phenyl]acetamide
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
IC50 = 2840 nM
|
|
|
|
CP0404078
|
N-[4-(diethylaminomethyl)phenyl]-2-(1H-indol-3-yl)acetamide
Show/Hide
|
C21H25N3O
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0404079
|
[4-(diethylaminomethyl)phenyl] 2-(1H-indol-3-yl)acetate
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
IC50 = 4610 nM
|
|
|
|
CP0442632
|
3-(1H-indol-3-yl)-N-[4-(pyrrolidin-1-ylmethyl)phenyl]propanamide
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508530
|
[4-(piperidin-1-ylmethyl)phenyl] 3-(1H-indol-3-yl)propanoate
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514828
|
3-(1H-indol-3-yl)-N-[4-(piperidin-1-ylmethyl)phenyl]propanamide
Show/Hide
|
C23H27N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514969
|
N-[4-(diethylaminomethyl)phenyl]-3-(1H-indol-3-yl)propanamide
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514971
|
[4-(pyrrolidin-1-ylmethyl)phenyl] 3-(1H-indol-3-yl)propanoate
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0523081
|
[4-(morpholin-4-ylmethyl)phenyl] 3-(1H-indol-3-yl)propanoate
Show/Hide
|
C22H24N2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0572597
|
3-(1H-indol-3-yl)-N-[4-(morpholin-4-ylmethyl)phenyl]propanamide
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0572598
|
[4-(diethylaminomethyl)phenyl] 3-(1H-indol-3-yl)propanoate
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0544247
|
2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[[1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carbonyl]amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]benzoate
Show/Hide
|
C54H70N6O9
|
3
|
| 1 |
Kd = 0.6761 nM
|
|
|
| 2 |
Ki = 0.1585 nM
|
|
|
| 3 |
Ki = 0.302 nM
|
|
|
|
CP0479122
|
4-(1-(3-(piperidin-1-yl)propyl)-3-(3-(piperidin-1-yl)propylthio)-1H-1,2,4-triazol-5-yl)pyridine
Show/Hide
|
C23H36N6S
|
1
|
| 1 |
Kd = 18 nM
|
|
|
|
CP0437725
|
4-(3-Piperidin-1-yl-propoxy)-benzoic acid 2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethyl ester
Show/Hide
|
C37H45F3N4O3S
|
1
|
| 1 |
Ki = 0.042 nM
|
|
|
|
CP0056575
|
1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piperidine
Show/Hide
|
C20H32N2O
|
4
|
| 1 |
Ki = 0.06026 nM
|
|
|
| 2 |
Ki = 0.2089 nM
|
|
|
| 3 |
Ki = 0.58 nM
|
|
|
| 4 |
Ki = 0.631 nM
|
|
|
|
CP0548960
|
4-chloro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine
Show/Hide
|
C20H31ClN2O
|
1
|
| 1 |
Ki = 0.068 nM
|
|
|
|
CP0403528
|
4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine
Show/Hide
|
C20H31FN2O
|
1
|
| 1 |
Ki = 0.094 nM
|
|
|
|
CP0235879
|
5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C26H27FN4O
|
2
|
| 1 |
Ki = 0.1 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0070912
|
3,5-dimethyl-N-[2-methyl-4-[(3S)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]phenyl]-1,2-oxazole-4-carboxamide
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0193419
|
6-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-N-methylnicotinamide
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
|
CP0284993
|
(4-propan-2-yl-1,4-diazepan-1-yl)-[1-[6-(trifluoromethyl)pyridin-3-yl]piperidin-4-yl]methanone
Show/Hide
|
C20H29F3N4O
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
|
CP0119048
|
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
Show/Hide
|
C17H26ClNO
|
9
|
| 1 |
Ki = 0.16 nM
|
|
|
| 2 |
Ki = 0.912 nM
|
|
|
| 3 |
Ki = 2.512 nM
|
|
|
| 4 |
Ki = 2.7 nM
|
|
|
| 5 |
Ki = 11.3 nM
|
|
|
| 6 |
Ki = 11.48 nM
|
|
|
| 7 |
Ki = 11.7 nM
|
|
|
| 8 |
Ki = 12 nM
|
|
|
| 9 |
Ki = 14.8 nM
|
|
|
|
CP0198045
|
CHEMBL1824245
Show/Hide
|
C28H38N2O
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0159421
|
5-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-N-methylpyrazine-2-carboxamide
Show/Hide
|
C20H24N4O2
|
1
|
| 1 |
Ki = 0.1905 nM
|
|
|
|
CP0517394
|
4-bromo-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine
Show/Hide
|
C20H31BrN2O
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0085130
|
1-[6-[(3-cyclobutyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)oxy]pyridin-3-yl]pyrrolidin-2-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 0.2042 nM
|
|
|
|
CP0287686
|
CHEMBL1824231
Show/Hide
|
C22H36N2O
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0414661
|
ethyl 1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carboxylate
Show/Hide
|
C23H36N2O3
|
2
|
| 1 |
Ki = 0.2291 nM
|
|
|
| 2 |
Ki = 0.2754 nM
|
|
|
|
CP0382124
|
3-[5-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,2,4-triazol-3-yl]pyridine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
Ki = 0.2399 nM
|
|
|
|
CP0553754
|
4,4-difluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine
Show/Hide
|
C20H30F2N2O
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0423208
|
N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Show/Hide
|
C34H42N2O
|
2
|
| 1 |
Ki = 0.25 nM
|
|
|
| 2 |
Ki = 0.3162 nM
|
|
|
|
CP0185938
|
1-[3-[4-(4-pyrrolidin-1-ylcyclohexyl)phenoxy]propyl]piperidine
Show/Hide
|
C24H38N2O
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0272014
|
1-[3-[4-[4-(azetidin-1-yl)cyclohexyl]phenoxy]propyl]piperidine
Show/Hide
|
C23H36N2O
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0517393
|
4-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)piperidine
Show/Hide
|
C19H29FN2O
|
1
|
| 1 |
Ki = 0.26 nM
|
|
|
|
CP0282267
|
N-benzyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C27H38N2O
|
1
|
| 1 |
Ki = 0.26 nM
|
|
|
|
CP0498763
|
(S)-1-(3-(4-((3-fluoropyrrolidin-1-yl)methyl)phenoxy)propyl)piperidine
Show/Hide
|
C19H29FN2O
|
1
|
| 1 |
Ki = 0.28 nM
|
|
|
|
CP0498764
|
(R)-1-(3-(4-((3-fluoropyrrolidin-1-yl)methyl)phenoxy)propyl)piperidine
Show/Hide
|
C19H29FN2O
|
1
|
| 1 |
Ki = 0.28 nM
|
|
|
|
CP0549758
|
2-amino-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 0.28 nM
|
|
|
|
CP0455492
|
N-benzyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C27H38N2O
|
1
|
| 1 |
Ki = 0.29 nM
|
|
|
|
CP0291533
|
N,N-dimethyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C22H36N2O
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0373413
|
(R)-3-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)pyrrolidine
Show/Hide
|
C18H27FN2O
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0551160
|
2-amino-7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C33H41N5O3
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0198048
|
1-methyl-4-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]piperazine
Show/Hide
|
C25H41N3O
|
1
|
| 1 |
Ki = 0.32 nM
|
|
|
|
CP0272012
|
1-[3-[4-(4-pyrrolidin-1-ylcyclohexyl)phenoxy]propyl]piperidine
Show/Hide
|
C24H38N2O
|
1
|
| 1 |
Ki = 0.33 nM
|
|
|
|
CP0452410
|
CHEMBL1824232
Show/Hide
|
C23H36N2O
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0437726
|
N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Show/Hide
|
C35H44N2O
|
1
|
| 1 |
Ki = 0.358 nM
|
|
|
|
CP0562510
|
(2R)-2-methyl-1-[2-(4-phenylmethoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0540297
|
N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C29H50N4O5
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0164808
|
4-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]morpholine
Show/Hide
|
C24H38N2O2
|
1
|
| 1 |
Ki = 0.41 nM
|
|
|
|
CP0549606
|
CHEMBL1824244
Show/Hide
|
C28H38N2O
|
1
|
| 1 |
Ki = 0.41 nM
|
|
|
|
CP0567366
|
2-methyl-5-[1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-yl]-1,3,4-oxadiazole
Show/Hide
|
C23H34N4O2
|
1
|
| 1 |
Ki = 0.4786 nM
|
|
|
|
CP0546064
|
4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0034701
|
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
Show/Hide
|
C13H16N2O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0110239
|
4-(1H-imidazol-4-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0198047
|
N-butyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C24H40N2O
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0562890
|
4-[4-(3-piperidin-1-ylpropoxy)phenyl]hepta-1,6-dien-4-ol
Show/Hide
|
C21H31NO2
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0198046
|
4-methyl-1-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]piperidine
Show/Hide
|
C26H42N2O
|
1
|
| 1 |
Ki = 0.56 nM
|
|
|
|
CP0191727
|
1-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]piperidin-4-ol
Show/Hide
|
C25H40N2O2
|
1
|
| 1 |
Ki = 0.57 nM
|
|
|
|
CP0040569
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-ol
Show/Hide
|
C20H32N2O2
|
1
|
| 1 |
Ki = 0.5888 nM
|
|
|
|
CP0551159
|
7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C33H43N5O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0214392
|
5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole
Show/Hide
|
C13H15IN2O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0164197
|
2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-5-(trifluoromethyl)-4(3H)-quinazolinone
Show/Hide
|
C23H24F3N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0191726
|
N-butyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C24H40N2O
|
1
|
| 1 |
Ki = 0.64 nM
|
|
|
|
CP0282263
|
1-[3-[4-(4-piperidin-1-ylcyclohexyl)phenoxy]propyl]piperidine
Show/Hide
|
C25H40N2O
|
1
|
| 1 |
Ki = 0.64 nM
|
|
|
|
CP0455493
|
CHEMBL1824240
Show/Hide
|
C24H38N2O2
|
1
|
| 1 |
Ki = 0.67 nM
|
|
|
|
CP0082544
|
[1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-yl]methanol
Show/Hide
|
C21H34N2O2
|
1
|
| 1 |
Ki = 0.6761 nM
|
|
|
|
CP0098027
|
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
Show/Hide
|
C6H10N4S
|
3
|
| 1 |
Ki = 0.7 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
| 3 |
Ki = 12.59 nM
|
|
|
|
CP0456768
|
4-[4-(3-piperidin-1-ylpropoxy)phenyl]heptan-4-ol
Show/Hide
|
C21H35NO2
|
1
|
| 1 |
Ki = 0.74 nM
|
|
|
|
CP0465253
|
1-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclopentan-1-ol
Show/Hide
|
C19H29NO2
|
1
|
| 1 |
Ki = 0.82 nM
|
|
|
|
CP0396279
|
1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidin-4-yl methanesulfonate
Show/Hide
|
C21H34N2O4S
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0494198
|
1-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]piperidin-4-ol
Show/Hide
|
C25H40N2O2
|
1
|
| 1 |
Ki = 0.92 nM
|
|
|
|
CP0549607
|
1-methyl-4-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexyl]piperazine
Show/Hide
|
C25H41N3O
|
1
|
| 1 |
Ki = 0.92 nM
|
|
|
|
CP0442834
|
1-[3-[4-(3,5-dimethyl-1,2,4-triazol-4-yl)phenoxy]propyl]piperidine
Show/Hide
|
C18H26N4O
|
1
|
| 1 |
Ki = 0.9333 nM
|
|
|
|
CP0415155
|
4-fluoro-1-(3-(4-(pyrrolidin-1-ylmethyl)phenoxy)propyl)piperidine
Show/Hide
|
C19H29FN2O
|
1
|
| 1 |
Ki = 0.99 nM
|
|
|
|
CP0069482
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(7-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone
Show/Hide
|
C28H38FN5O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0069483
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,10,12-tetraen-8-yl)piperidin-1-yl]methanone
Show/Hide
|
C26H33FN8OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0075201
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)piperidin-1-yl]methanone
Show/Hide
|
C27H36FN5O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0155226
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(1,2,3,5-tetrahydro-1,4-benzodiazepin-4-yl)piperidin-1-yl]methanone
Show/Hide
|
C26H35FN6O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0891661
|
3-(1H-imidazol-4-yl)propyl N-cyclohexyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C20H27BrCl2N4S
|
1
|
| 1 |
Ki = 1.023 nM
|
|
|
|
CP0400807
|
3-(1H-imidazol-5-yl)propyl N'-[(4-chlorophenyl)methyl]-N-cyclohexylcarbamimidothioate
Show/Hide
|
C20H27ClN4S
|
1
|
| 1 |
Ki = 1.047 nM
|
|
|
|
CP0543412
|
(2S,5S)-2-benzyl-5-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine
Show/Hide
|
C26H37N3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0917429
|
3-(1H-imidazol-4-yl)propyl N-cyclohexyl-N'-(4-nitrobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C20H28BrN5O2S
|
1
|
| 1 |
Ki = 1.148 nM
|
|
|
|
CP0481297
|
5-fluoro-2-(pyridin-2-yl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C25H25FN4O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0371973
|
3-(2-chlorophenothiazin-10-yl)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C31H38ClN3OS
|
1
|
| 1 |
Ki = 1.21 nM
|
|
|
|
CP0502020
|
(2R)-2-methyl-1-(2-naphthalen-2-ylethyl)pyrrolidine
Show/Hide
|
C17H21N
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0375178
|
3-[4-(3-piperidin-1-ylpropoxy)phenyl]pentan-3-ol
Show/Hide
|
C19H31NO2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0371976
|
(3E)-3-(2-chlorothioxanthen-9-ylidene)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C32H37ClN2OS
|
1
|
| 1 |
Ki = 1.54 nM
|
|
|
|
CP0396144
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carboxylic acid
Show/Hide
|
C21H32N2O3
|
2
|
| 1 |
Ki = 1.585 nM
|
|
|
| 2 |
Ki = 12.88 nM
|
|
|
|
CP0373024
|
(2S)-2-methyl-1-[2-(4-phenylmethoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0859147
|
3-(1H-imidazol-4-yl)propyl N'-4-cyanobenzyl-N-cyclohexylcarbamimidothioate dihydrobromide
Show/Hide
|
C21H28BrN5S
|
1
|
| 1 |
Ki = 1.622 nM
|
|
|
|
CP0198049
|
4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-one
Show/Hide
|
C20H29NO2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0334052
|
1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)piperidin-4-ol
Show/Hide
|
C26H27FN4O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0488696
|
4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]cyclohexan-1-ol
Show/Hide
|
C21H33NO2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0473959
|
2-[4-[4-[(3aR,6aR)-5-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]phenyl]phenyl]pyridazin-3-one
Show/Hide
|
C23H24N4O
|
2
|
| 1 |
Ki = 1.9 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0920493
|
1-Cyclopropyl-6-fluoro-4-oxo-7-(4-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C32H39FN4O4
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0526595
|
1-(4-(3-(4-benzylpiperidin-1-yl)propoxy)phenyl)-5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C33H33FN4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0070658
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(1,3-dihydroisoindol-2-yl)piperidin-1-yl]methanone
Show/Hide
|
C25H32FN5O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0133131
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(8-methoxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone
Show/Hide
|
C28H38FN5O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0155225
|
2-[1-[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidine-4-carbonyl]piperidin-4-yl]-3,4-dihydro-1H-isoquinoline-7-carbonitrile
Show/Hide
|
C27H33FN6O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0175671
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(3,4-dihydro-1H-isoquinolin-2-yl)piperidin-1-yl]methanone
Show/Hide
|
C26H34FN5O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0200250
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(5,7-dihydrobenzo[d][2]benzazepin-6-yl)piperidin-1-yl]methanone
Show/Hide
|
C31H36FN5O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0218031
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(5-fluoro-1,3-dihydroisoindol-2-yl)piperidin-1-yl]methanone
Show/Hide
|
C25H31F2N5O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0043142
|
trans-H2-PAT(-)
Show/Hide
|
C18H21N
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0398379
|
(2R,4S)-4-cyclohexyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H28ClN
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0398758
|
(2S,4R)-4-cyclohexyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H28ClN
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0562170
|
(2S)-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine
Show/Hide
|
C19H31N3O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0568800
|
(3S,6Z)-3-benzyl-6-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]piperazine-2,5-dione
Show/Hide
|
C26H31N3O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0414666
|
8-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C22H34N2O3
|
1
|
| 1 |
Ki = 2.042 nM
|
|
|
|
CP0548490
|
9-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C20H24N6OS
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0383908
|
(2E)-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
|
C24H27NO2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0489791
|
(2E)-5-fluoro-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
|
C24H26FNO2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0462484
|
(2R)-1-[2-(4-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0551161
|
4-phenyl-7-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0921851
|
1-[3-(3-(4-tert-Butylphenoxy)propoxy)propyl]azepane hydrogen oxalate
Show/Hide
|
C24H39NO6
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0396278
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-one
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0441243
|
2-(ethylthio)-5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2,3-dihydro-1H-benzo[d]imidazole
Show/Hide
|
C23H30FN3OS
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0044443
|
4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-ol
Show/Hide
|
C20H31NO2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0255637
|
1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-benzyl]-piperazine; compound with oxalic acid
Show/Hide
|
C25H34N2O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0575291
|
4-[4-(3-piperidin-1-ylpropoxy)benzoyl]piperazin-2-one
Show/Hide
|
C19H27N3O3
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0905750
|
cyclohexyl(4-(3-(piperidin-1-yl)propoxy)phenyl)methanol
Show/Hide
|
C21H33NO2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0085944
|
2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
Ki = 2.951 nM
|
|
|
|
CP0380961
|
N-ethyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C23H37N3O2
|
1
|
| 1 |
Ki = 2.951 nM
|
|
|
|
CP0398757
|
(2S,4R)-4-(3-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0949921
|
1-[3-(3-(3-Methoxyphenoxy)propoxy)propyl]azepane hydrogen oxalate
Show/Hide
|
C21H33NO7
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0530965
|
N-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]cyclohexan-1-amine
Show/Hide
|
C21H34N2O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0450611
|
2-(4-piperidin-1-ylpiperidin-1-yl)-5-pyrazolo[1,5-a]pyridin-7-yl-1,3,4-thiadiazole
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0502173
|
8-Chloro-11-{4-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperazin-1-yl}-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C32H38ClN5O
|
1
|
| 1 |
Ki = 3.27 nM
|
|
|
|
CP0948140
|
4-(4-(3-(piperidin-1-yl)propoxy)phenyl)butan-2-ol
Show/Hide
|
C18H29NO2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0235890
|
4-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)morpholine
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0432335
|
2-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazole
Show/Hide
|
C19H25N7S
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0486785
|
5-methyl-4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-2-phenyl-1,3-oxazole
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0491777
|
N-methyl-4-(3-piperidin-1-ylpropoxy)-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]benzamide
Show/Hide
|
C34H40N2O2
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0871037
|
1-[3-(3-(4-Chlorophenoxy)propoxy)propyl]-4-methylpiperidine hydrogen oxalate
Show/Hide
|
C20H30ClNO6
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0103739
|
2-(1,4'-bipiperidin-1'-yl)-5-(6-methoxypyridin-2-yl)-1,3,4-thiadiazole
Show/Hide
|
C18H25N5OS
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0459650
|
5-fluoro-1-(4-(3-(4-methyl-1,4-diazepan-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C27H30FN5O
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0551830
|
(3Z,6Z)-3-benzylidene-6-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]piperazine-2,5-dione
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0575290
|
(3Z)-1-acetyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]piperazine-2,5-dione
Show/Hide
|
C21H27N3O4
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0917938
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)cyclohexanol
Show/Hide
|
C20H31NO2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0416506
|
(2E)-2-benzylidene-5-(3-piperidin-1-ylpropoxy)-3H-inden-1-one
Show/Hide
|
C24H27NO2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0919630
|
Methyl 2-(4-(3-(piperidin-1-yl)propoxy)phenyl)thiazolidine-4-carboxylate hydrogenoxalate
Show/Hide
|
C21H30N2O7S
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0310819
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0113934
|
1-(3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)phenyl)ethanone
Show/Hide
|
C20H26N4OS
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0298087
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-pyrazolo[1,5-a]pyridin-7-yl-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C23H26N6O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0845921
|
2-methyl-4-(4-(3-(piperidin-1-yl)propoxy)phenyl)butan-2-ol
Show/Hide
|
C19H31NO2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0313989
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(6,11-dihydrobenzo[c][1]benzazepin-5-yl)piperidin-1-yl]methanone
Show/Hide
|
C31H36FN5O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0513046
|
(2S,4R)-4-(4-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0876160
|
4-(4-(3-(piperidin-1-yl)propoxy)phenyl)tetrahydro-2H-pyran-4-ol
Show/Hide
|
C19H29NO3
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0513321
|
4-[5-methyl-4-(2-pyrrolidin-1-ylethoxy)-1,3-thiazol-2-yl]benzonitrile
Show/Hide
|
C17H19N3OS
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0494844
|
azetidin-1-yl-[6-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]pyridin-2-yl]methanone
Show/Hide
|
C21H28N6OS
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0576922
|
(3Z,6S)-1-acetyl-6-benzyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]piperazine-2,5-dione
Show/Hide
|
C28H33N3O4
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0542599
|
4-phenyl-8-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0435988
|
2-(4-piperidin-1-ylpiperidin-1-yl)-5-quinolin-8-yl-1,3,4-thiadiazole
Show/Hide
|
C21H25N5S
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0875997
|
3-(1H-imidazol-4-yl)propyl N-butyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C18H25BrCl2N4S
|
1
|
| 1 |
Ki = 4.677 nM
|
|
|
|
CP0307681
|
(S)-5-fluoro-1-(4-(3-(3-isopropylpyrrolidin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C28H31FN4O
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0894044
|
3-(1H-imidazol-4-yl)propyl N-butyl-N'-(4-chlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C18H26BrClN4S
|
1
|
| 1 |
Ki = 4.898 nM
|
|
|
|
CP0371972
|
N-methyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]acetamide
Show/Hide
|
C35H42N2O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0568795
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione
Show/Hide
|
C19H27N3O3
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0575292
|
1-benzyl-4-[4-(3-piperidin-1-ylpropoxy)benzoyl]piperazin-2-one
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0462543
|
1-[2-(4-phenylmethoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0462547
|
(2R)-2-methyl-1-[2-(3-methylphenyl)ethyl]pyrrolidine
Show/Hide
|
C14H21N
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0486790
|
(2R)-2-methyl-1-[2-(4-methylphenyl)ethyl]pyrrolidine
Show/Hide
|
C14H21N
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0916464
|
(Z)-5-(4-(3-(Piperidin-1-yl)propoxy)benzylidene)-2-thioxothiazolidin-4-one
Show/Hide
|
C18H22N2O2S2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0553698
|
1-(4-(3-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)propoxy)phenyl)-5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0426702
|
1-[4-[3-(4-pyridin-4-ylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0424073
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0493560
|
(2R)-2-[[4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methoxy]phenyl]methylamino]propanamide
Show/Hide
|
C25H35N3O3
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0457928
|
(5-methyl-2-phenyl-1,3-thiazol-4-yl) 4-piperidin-1-ylpiperidine-1-carboxylate
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0503320
|
CHEMBL1824251
Show/Hide
|
C27H38N2O3S
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0535858
|
N,N-dimethyl-4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]aniline
Show/Hide
|
C15H24N2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0398352
|
(2R,4S)-4-(4-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0575410
|
7-[(2,6-dichlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H27Cl2N5
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0527648
|
2-(1,4'-bipiperidin-1'-yl)-5-(6-methylpyridin-2-yl)-1,3,4-thiadiazole
Show/Hide
|
C18H25N5S
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0569824
|
(2E)-5-[(4-bromophenyl)methoxy]-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
|
C31H32BrNO3
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0845920
|
2-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-2-ol
Show/Hide
|
C17H27NO2
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
|
CP0948139
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)but-3-en-1-ol
Show/Hide
|
C18H27NO2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0070659
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-(4-pyrido[3,2-b][1,4]benzothiazin-10-ylpiperidin-1-yl)methanone
Show/Hide
|
C28H31FN6OS
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0075202
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-(4-phenothiazin-10-ylpiperidin-1-yl)methanone
Show/Hide
|
C29H32FN5OS
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0085104
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(5,7-dihydropyrrolo[3,4-b]pyridin-6-yl)piperidin-1-yl]methanone
Show/Hide
|
C24H31FN6O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0487152
|
5-methyl-4-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]-2-pyrazin-2-yl-1,3-thiazole
Show/Hide
|
C21H24N4OS
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0444572
|
4-[[4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl]benzonitrile
Show/Hide
|
C24H28N6
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0397758
|
5-methyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
Ki = 7.079 nM
|
|
|
|
CP0871057
|
1-[3-(2-(3-Methoxyphenoxy)ethoxy]propyl-4-methylpiperidine hydrogen oxalate
Show/Hide
|
C20H31NO7
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0508723
|
3-benzoyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
Ki = 7.244 nM
|
|
|
|
CP0386139
|
4,5-diphenyl-2-(3-(piperidin-1-yl)propylthio)thiazole
Show/Hide
|
C23H26N2S2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0870784
|
1-[3-(3-(4-tert-Butylphenoxy)propoxy)propyl]-4-methyl piperidine hydrogen oxalate
Show/Hide
|
C24H39NO6
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0861178
|
(Z)-5-(4-(3-(Piperidin-1-yl)propoxy)benzylidene)thiazolidine-2,4-dione
Show/Hide
|
C18H22N2O3S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0918528
|
1-(3-(4-(4,5-Dihydro-1H-imidazol-2-yl)phenoxy)propyl)piperidine
Show/Hide
|
C17H25N3O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0431372
|
5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazole-2(3H)-thione
Show/Hide
|
C21H24FN3OS
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0202866
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)pyridin-2-ol
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0398377
|
(2S,4R)-4-(4-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0527811
|
(2R,4S)-4-(4-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0527661
|
1-(2-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)phenyl)ethanone
Show/Hide
|
C20H26N4OS
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0801652
|
1-(3-(4-tert-pentylphenoxy)propyl)piperidine
Show/Hide
|
C19H31NO
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0433047
|
1-[4-(3-piperidin-1-ylpropoxy)phenyl]prop-2-en-1-ol
Show/Hide
|
C17H25NO2
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0441241
|
5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0486787
|
(2S)-1-[2-(4-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 8.9 nM
|
|
|
|
CP0894043
|
3-(1H-Imidazol-4-yl)propyl N-Benzyl-N'-cyclohexylcarbamimidothioate dihydrobromide
Show/Hide
|
C20H29BrN4S
|
1
|
| 1 |
Ki = 9.772 nM
|
|
|
|
CP0382235
|
(2S)-2-methyl-1-[2-(2,4,6-trimethylphenyl)ethyl]pyrrolidine
Show/Hide
|
C16H25N
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0165547
|
2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-c]pyridine
Show/Hide
|
C16H21ClN4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0282261
|
N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]pyridin-2-yl]acetamide
Show/Hide
|
C23H28N6OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0951220
|
2-(4-(3-(Piperidin-1-yl)propoxy)phenyl)thiazolidine-4-carboxylic acid
Show/Hide
|
C18H26N2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0450682
|
6-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-quinolin-2-one
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0483366
|
(2S,4R)-4-(3-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0176249
|
1-[4-[3-(4-pyridin-4-ylpiperazin-1-yl)propoxy]phenyl]ethanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 10.2 nM
|
|
|
|
CP0176032
|
N-methyl-N-[[1-methyl-5-(3-piperidin-1-ylpropoxy)indol-2-yl]methyl]prop-2-yn-1-amine
Show/Hide
|
C22H31N3O
|
1
|
| 1 |
Ki = 10.8 nM
|
|
|
|
CP0374371
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-N-prop-2-ynylpiperidine-4-carboxamide
Show/Hide
|
C24H35N3O2
|
1
|
| 1 |
Ki = 10.96 nM
|
|
|
|
CP0459652
|
1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)piperidine-3-carboxamide
Show/Hide
|
C27H28FN5O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0474986
|
1-(4-(3-(3,5-dimethylpiperidin-1-yl)propoxy)phenyl)-5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C28H31FN4O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0535857
|
(2R)-2-methyl-1-[2-(2,4,6-trimethylphenyl)ethyl]pyrrolidine
Show/Hide
|
C16H25N
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0041914
|
4-(3-(piperidin-1-yl)propoxy)benzonitrile
Show/Hide
|
C15H20N2O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0305338
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-[2-(trifluoromethyl)phenothiazin-10-yl]piperidin-1-yl]methanone
Show/Hide
|
C30H31F4N5OS
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0239657
|
cyclopropyl-[4-(3-piperidin-1-ylpropoxy)phenyl]methanone
Show/Hide
|
C18H25NO2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0575812
|
(2E)-6-methoxy-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
|
C25H29NO3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0542598
|
4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0544077
|
4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0036621
|
4,5-diphenyl-2-(3-(piperidin-1-yl)propoxy)thiazole
Show/Hide
|
C23H26N2OS
|
1
|
| 1 |
Ki = 11.2 nM
|
|
|
|
CP0562171
|
1-benzyl-4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazin-2-one
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
Ki = 11.3 nM
|
|
|
|
CP0109570
|
2-(1,4'-bipiperidin-1'-yl)-5-(3-chloro-5-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C19H25ClN4OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0413097
|
3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)-5-methoxybenzonitrile
Show/Hide
|
C20H25N5OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0420818
|
2-[3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]phenyl]pyridazin-3-one
Show/Hide
|
C22H26N6OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0920437
|
1-[3-(2-(3-Methoxyphenoxy)ethoxy]propyl-3-methylpiperidine hydrogen oxalate
Show/Hide
|
C20H31NO7
|
1
|
| 1 |
Ki = 12.5 nM
|
|
|
|
CP0262730
|
6-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]chromen-4-one
Show/Hide
|
C21H24N4O2S
|
1
|
| 1 |
Ki = 12.7 nM
|
|
|
|
CP0888634
|
1-[3-(3-(4-Chlorophenoxy)propoxy)propyl]azepane hydrogen oxalate
Show/Hide
|
C21H32ClNO6
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0448166
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
|
CP0377435
|
5-fluoro-1-(4-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole
Show/Hide
|
C26H28FN5O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0095048
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-4-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C21H24FN5S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0160289
|
7-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C20H24N6OS
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0961076
|
(4-(3-(piperidin-1-yl)propoxy)phenyl)(tetrahydro-2H-pyran-4-yl)methanol
Show/Hide
|
C20H31NO3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0425035
|
4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C9H15N5
|
1
|
| 1 |
Ki = 13.8 nM
|
|
|
|
CP0562511
|
(2S)-2-methyl-1-(2-naphthalen-2-ylethyl)pyrrolidine
Show/Hide
|
C17H21N
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0553700
|
2-ethoxy-5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2,3-dihydro-1H-benzo[d]imidazole
Show/Hide
|
C23H30FN3O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0462544
|
5-methoxy-2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1H-indole
Show/Hide
|
C16H22N2O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0494838
|
2-(1,4'-bipiperidin-1'-yl)-5-(3,5-dimethoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C20H28N4O2S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0205480
|
6-(6-methylpyridin-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0273381
|
6-(3-methylpyridin-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0876159
|
3-(4-(3-(piperidin-1-yl)propoxy)phenyl)prop-2-yn-1-ol
Show/Hide
|
C17H23NO2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0069481
|
[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(6-methyl-1,2,4,5-tetrahydroazepino[4,5-b]indol-3-yl)piperidin-1-yl]methanone
Show/Hide
|
C30H39FN6O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0564939
|
1-[4-[4-(4-pyridin-4-ylpiperazin-1-yl)butoxy]phenyl]propan-1-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 15.4 nM
|
|
|
|
CP0289055
|
methyl 1-[3-[4-(5-fluoro-2-pyridin-2-ylbenzimidazol-1-yl)phenoxy]propyl]piperidine-4-carboxylate
Show/Hide
|
C28H29FN4O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0535856
|
(2R)-1-[2-(3-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0181646
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)nicotinonitrile
Show/Hide
|
C22H24N6S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0341379
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)pyridin-2-amine
Show/Hide
|
C21H26N6S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0527647
|
2-(1,4'-bipiperidin-1'-yl)-5-(3-fluoro-5-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C19H25FN4OS
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0959801
|
1-(3-(4-(tert-butyl)phenoxy)propyl)-4-(pyridin-4-yl)piperazine
Show/Hide
|
C22H31N3O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0566105
|
N-[3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]phenyl]acetamide
Show/Hide
|
C20H27N5OS
|
1
|
| 1 |
Ki = 16.5 nM
|
|
|
|
CP0875996
|
3-(1H-imidazol-4-yl)propyl N-benzyl-N'-(4-chlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C21H24BrClN4S
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0502026
|
5-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1,2-thiazole
Show/Hide
|
C10H16N2S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0296482
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)pyrazin-2-amine
Show/Hide
|
C20H25N7S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0562422
|
2-amino-4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0531885
|
1-(3-(4-(fluoromethyl)phenoxy)propyl)piperidine
Show/Hide
|
C15H22FNO
|
1
|
| 1 |
Ki = 17.3 nM
|
|
|
|
CP0386692
|
5,6-dimethyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
Ki = 17.78 nM
|
|
|
|
CP0494842
|
2-isoquinolin-5-yl-5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazole
Show/Hide
|
C21H25N5S
|
1
|
| 1 |
Ki = 17.8 nM
|
|
|
|
CP0486786
|
2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-1H-indole
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0130341
|
6-imidazo[1,2-a]pyrazin-3-yl-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0901043
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)cyclobutanol
Show/Hide
|
C18H27NO2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0520073
|
4-[[2-chloro-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl]benzonitrile
Show/Hide
|
C24H27ClN6
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0564598
|
oxalic acid;1-[6-(3-phenylphenoxy)hexyl]azepane
Show/Hide
|
C26H35NO5
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0953232
|
1-[3-(3-(3-Methoxyphenoxy)propoxy)propyl]-4-methylpiperidine hydrogen oxalate
Show/Hide
|
C21H33NO7
|
1
|
| 1 |
Ki = 18.6 nM
|
|
|
|
CP0895744
|
3-(1H-Imidazol-4-yl)propyl N-Cyclohexyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C18H31BrN4S
|
1
|
| 1 |
Ki = 18.62 nM
|
|
|
|
CP0845919
|
4-(4-(3-(piperidin-1-yl)propoxy)phenyl)but-3-yn-1-ol
Show/Hide
|
C18H25NO2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0125169
|
[5-(1,3-benzothiazol-2-yl)thiophen-2-yl]-(4-ethylpiperazin-1-yl)methanone
Show/Hide
|
C18H19N3OS2
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0167222
|
3-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)thiazolidine
Show/Hide
|
C24H23FN4OS
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0522894
|
1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)piperidine-4-carboxamide
Show/Hide
|
C27H28FN5O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0440955
|
(2S)-2-methyl-1-[2-(4-nitrophenyl)ethyl]pyrrolidine
Show/Hide
|
C13H18N2O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0203201
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-3-yl)thiazolo[4,5-c]pyridine
Show/Hide
|
C21H24FN5S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0373632
|
2-(3-(piperidin-1-yl)propoxy)-5-(3-(piperidin-1-yl)propyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
Show/Hide
|
C22H38N4OS
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0410202
|
5-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-quinolin-2-one
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0462548
|
2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenol
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0553699
|
(2S)-2-[[4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methoxy]phenyl]methylamino]propanamide
Show/Hide
|
C25H35N3O3
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0552238
|
4-[5-methyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazol-2-yl]benzonitrile
Show/Hide
|
C19H23N3OS
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0042242
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)nicotinonitrile
Show/Hide
|
C22H24N6S
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0812162
|
1-(3-(4-tert-butylphenoxy)propyl)piperidine
Show/Hide
|
C18H29NO
|
2
|
| 1 |
Ki = 22 nM
|
|
|
| 2 |
Ki = 131 nM
|
|
|
|
CP0513320
|
2-(4-chlorophenyl)-5-methyl-4-(2-pyrrolidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C16H19ClN2OS
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0470493
|
4-[2-[2-chloro-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]ethyl]morpholine
Show/Hide
|
C22H33ClN6O
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0423900
|
6-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H25N5O2S
|
1
|
| 1 |
Ki = 22.1 nM
|
|
|
|
CP0578293
|
(3Z)-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]piperazine-2,5-dione
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
Ki = 22.3 nM
|
|
|
|
CP0845918
|
(4-(3-(piperidin-1-yl)propoxy)phenyl)methanol
Show/Hide
|
C15H23NO2
|
1
|
| 1 |
Ki = 22.7 nM
|
|
|
|
CP0319073
|
2-methyl-5-[3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]phenyl]-1,3,4-oxadiazole
Show/Hide
|
C21H26N6OS
|
1
|
| 1 |
Ki = 22.8 nM
|
|
|
|
CP0095046
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)-2-fluorobenzonitrile
Show/Hide
|
C23H24FN5S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0426628
|
5-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)isophthalonitrile
Show/Hide
|
C20H22N6S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0391371
|
6-(6-methoxypyridin-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0491234
|
US8796297, 25
Show/Hide
|
C8H13N5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0410200
|
2-methyl-5-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1,3-benzoxazole
Show/Hide
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C20H25N5OS
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1
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| 1 |
Ki = 24.5 nM
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CP0181647
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2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiazolo[4,5-b]pyridine
Show/Hide
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C20H24N6S
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1
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| 1 |
Ki = 25 nM
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CP0181648
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2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiazolo[4,5-c]pyridine
Show/Hide
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C20H24N6S
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1
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| 1 |
Ki = 25 nM
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CP0231999
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5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)pyridin-2-amine
Show/Hide
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C21H26N6S
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1
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| 1 |
Ki = 25 nM
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CP0338990
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9-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C24H26N6O2
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1
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| 1 |
Ki = 25 nM
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CP0459600
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2-[2-[(3R)-3-piperidin-1-ylpyrrolidin-1-yl]-1,3-benzothiazol-6-yl]pyridazin-3-one
Show/Hide
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C20H23N5OS
|
1
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| 1 |
Ki < 25 nM
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CP0535854
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5-methyl-2-phenyl-4-(2-pyrrolidin-1-ylethyl)-1,3-oxazole
Show/Hide
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C16H20N2O
|
1
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| 1 |
Ki = 26 nM
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CP0551447
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7-[(4-chlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
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C23H28ClN5
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1
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| 1 |
Ki = 26 nM
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CP0505152
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(2S)-2-methyl-1-[2-(4-methylphenyl)ethyl]pyrrolidine
Show/Hide
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C14H21N
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1
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| 1 |
Ki = 27 nM
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CP0232079
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N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]pyridin-2-yl]acetamide
Show/Hide
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C23H28N6OS
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1
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| 1 |
Ki = 27 nM
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CP0072380
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8-[1-[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidine-4-carbonyl]piperidin-4-yl]-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,10,12-tetraen-7-one
Show/Hide
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C26H31FN8O2S
|
1
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| 1 |
Ki = 27 nM
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CP0949662
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1-[3-(2-(-4-tert-Butylphenoxy)ethoxy)propyl]-3-methylpiperidine hydrogen oxalate
Show/Hide
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C23H37NO6
|
1
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| 1 |
Ki = 27.3 nM
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CP0871060
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1-[3-(3-(4-Chlorophenoxy)propoxy)propyl]-3-methylpiperidine hydrogen oxalate
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C20H30ClNO6
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1
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| 1 |
Ki = 27.9 nM
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CP0382232
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5-methyl-4-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-2-phenyl-1,3-oxazole
Show/Hide
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C17H22N2O
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1
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| 1 |
Ki = 28 nM
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CP0095045
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4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)benzonitrile
Show/Hide
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C23H25N5S
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1
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| 1 |
Ki = 28 nM
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CP0430407
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(R)-3-(1H-imidazol-4-yl)propyl octan-2-ylcarbamate
Show/Hide
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C15H27N3O2
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1
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| 1 |
Ki = 28 nM
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CP0549643
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2-(1,4'-bipiperidin-1'-yl)-5-(2-methoxythiazol-5-yl)-1,3,4-thiadiazole
Show/Hide
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C16H23N5OS2
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1
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| 1 |
Ki = 28 nM
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CP0470180
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US8796297, 7
Show/Hide
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C8H15N5
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1
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| 1 |
Ki = 28.2 nM
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CP0410478
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3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-1H-pyrimidine-2,4-dione
Show/Hide
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C19H25N3O3
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1
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| 1 |
Ki = 28.84 nM
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CP0443930
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1-[3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]phenyl]ethanol
Show/Hide
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C20H28N4OS
|
1
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| 1 |
Ki = 29 nM
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CP0505150
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1-(2-naphthalen-2-ylethyl)pyrrolidine
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C16H19N
|
1
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| 1 |
Ki = 30 nM
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CP0410057
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2-(1,4'-bipiperidin-1'-yl)-5-(pyridin-2-yl)-1,3,4-thiadiazole
Show/Hide
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C17H23N5S
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1
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| 1 |
Ki = 30 nM
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CP0386622
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trans-H2-PAT(+)
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C18H21N
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1
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| 1 |
Ki = 30 nM
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CP0398351
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(2S,4R)-4-(3-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
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C18H21BrClN
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1
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| 1 |
Ki = 30 nM
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CP0435630
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2-chloro-7-[(4-fluorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
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C23H27ClFN5
|
1
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| 1 |
Ki = 30 nM
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CP0959802
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1-(3-(4-(tert-pentyl)phenoxy)propyl)-4-(pyridin-4-yl)piperazine
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C23H33N3O
|
1
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| 1 |
Ki = 30.6 nM
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CP0562513
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(2S)-1-[2-(2-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
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C14H21NO
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1
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| 1 |
Ki = 31 nM
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CP0499094
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N-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]acetamide
Show/Hide
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C18H25N5OS
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1
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| 1 |
Ki = 31 nM
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CP0391415
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4-[2-[4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]ethyl]morpholine
Show/Hide
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C22H34N6O
|
1
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| 1 |
Ki = 31 nM
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CP0546060
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2-amino-4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C24H24N4O2
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1
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| 1 |
Ki = 31 nM
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CP0397761
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3-benzoyl-5-methyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
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C27H31N3O4
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1
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| 1 |
Ki = 31.62 nM
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CP0522311
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2-(1,4'-bipiperidin-1'-yl)-5-(3-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
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C19H26N4OS
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1
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| 1 |
Ki = 31.9 nM
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CP0409485
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(2S)-2-methyl-1-[2-(3-methylphenyl)ethyl]pyrrolidine
Show/Hide
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C14H21N
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1
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| 1 |
Ki = 32 nM
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CP0520549
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4,5-diphenyl-2-(3-(piperidin-1-yl)propylthio)oxazole
Show/Hide
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C23H26N2OS
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1
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| 1 |
Ki = 32 nM
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CP0905749
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2-(4-(3-(piperidin-1-yl)propoxy)phenyl)ethanol
Show/Hide
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C16H25NO2
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1
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| 1 |
Ki = 32 nM
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CP0542868
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(2E)-6-[(4-bromophenyl)methoxy]-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
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C31H32BrNO3
|
1
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| 1 |
Ki = 32 nM
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CP0873064
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3-(1H-imidazol-4-yl)propyl N-benzyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
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C21H23BrCl2N4S
|
1
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| 1 |
Ki = 32.36 nM
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CP0315357
|
3-methyl-1-(5-naphthalen-1-yloxypentyl)piperidine
Show/Hide
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C21H29NO
|
1
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| 1 |
Ki = 32.8 nM
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CP0454315
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5-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-1,2-thiazole
Show/Hide
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C10H16N2S
|
1
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| 1 |
Ki = 33 nM
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CP0534977
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1-(3-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)phenyl)ethanone
Show/Hide
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C24H28N4OS
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1
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| 1 |
Ki = 33 nM
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CP0291579
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6-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
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C23H27N7O
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1
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| 1 |
Ki = 33 nM
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CP0518798
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(2E)-5-methoxy-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylidene]-3H-inden-1-one
Show/Hide
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C25H29NO3
|
1
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| 1 |
Ki = 33 nM
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CP0462718
|
US8796297, 22
Show/Hide
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C7H11N5
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1
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| 1 |
Ki = 33.1 nM
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CP0457790
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5-ethyl-2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
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C14H22N2
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1
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| 1 |
Ki = 34 nM
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CP0467737
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(2R)-2-methyl-1-(2-thiophen-2-ylethyl)pyrrolidine
Show/Hide
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C11H17NS
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1
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| 1 |
Ki = 34 nM
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CP0448167
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3-benzoyl-5,6-dimethyl-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-2,4-dione
Show/Hide
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C28H33N3O4
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1
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| 1 |
Ki = 34.67 nM
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CP0562512
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(2R)-1-[2-(2-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
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C14H21NO
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1
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| 1 |
Ki = 35 nM
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CP0095053
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2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl)thiazolo[4,5-c]pyridine
Show/Hide
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C21H24FN5S
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1
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| 1 |
Ki = 35 nM
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CP0165548
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2-(1,4'-bipiperidin-1'-yl)-6-(6-methoxypyridin-3-yl)thiazolo[4,5-b]pyridine
Show/Hide
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C22H27N5OS
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1
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| 1 |
Ki = 35 nM
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CP0376954
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2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridine-6-carbonitrile
Show/Hide
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C17H21N5S
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1
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| 1 |
Ki = 35 nM
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CP0338989
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2-(4-piperidin-1-ylpiperidin-1-yl)-6-quinolin-8-yl-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
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C25H27N5O
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1
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| 1 |
Ki = 35 nM
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CP0470494
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7-[(4-fluorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
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C23H28FN5
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1
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| 1 |
Ki = 35 nM
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CP0420819
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7-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1H-quinolin-2-one
Show/Hide
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C21H25N5OS
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1
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| 1 |
Ki = 35.9 nM
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CP0540204
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2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridine-6-carbonitrile
Show/Hide
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C17H21N5S
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1
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| 1 |
Ki = 36 nM
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CP0393240
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2-(1,4'-bipiperidin-1'-yl)-5-(2-fluorophenyl)-1,3,4-thiadiazole
Show/Hide
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C18H23FN4S
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1
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| 1 |
Ki = 36 nM
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CP0527660
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2-(1,4'-bipiperidin-1'-yl)-5-o-tolyl-1,3,4-thiadiazole
Show/Hide
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C19H26N4S
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1
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| 1 |
Ki = 36 nM
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CP0212806
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2-fluoro-5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]benzonitrile
Show/Hide
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C23H24FN5O
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1
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| 1 |
Ki = 36 nM
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CP0042614
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[1-[(2-aminopyridin-4-yl)methyl]-4-fluoropiperidin-4-yl]-[4-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)piperidin-1-yl]methanone
Show/Hide
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C27H36FN5O
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1
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| 1 |
Ki = 36 nM
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CP0549760
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2-amino-4-phenyl-7-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C25H26N4O2
|
1
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| 1 |
Ki = 36 nM
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CP0541921
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4-(2-cyclohexylethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
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C16H25N5
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1
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| 1 |
Ki = 36.31 nM
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CP0478960
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4-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)benzonitrile
Show/Hide
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C19H23N5S
|
1
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| 1 |
Ki = 36.4 nM
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CP0284455
|
4-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]benzonitrile
Show/Hide
|
C23H25N5O
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1
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| 1 |
Ki = 37 nM
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CP0391372
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6-(6-chloropyridin-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
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C21H24ClN5O
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1
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| 1 |
Ki = 37 nM
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CP0503210
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2-(4-piperidin-1-ylpiperidin-1-yl)-6-pyridin-4-yl-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
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C21H25N5O
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1
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| 1 |
Ki = 37 nM
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CP0552696
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1-[4-(4-tert-butylphenoxy)butyl]-4-pyridin-4-ylpiperazine
Show/Hide
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C23H33N3O
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1
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| 1 |
Ki = 37.8 nM
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CP0565357
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tert-butyl 5,6-dimethyl-2,4-dioxo-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-1-carboxylate
Show/Hide
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C26H37N3O5
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1
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| 1 |
Ki = 38.02 nM
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CP0405289
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2-(1,4'-bipiperidin-1'-yl)-5-(4-fluorophenyl)-1,3,4-thiadiazole
Show/Hide
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C18H23FN4S
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1
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| 1 |
Ki = 39 nM
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CP0429651
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(2E)-2-benzylidene-6-(3-piperidin-1-ylpropoxy)-3H-inden-1-one
Show/Hide
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C24H27NO2
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1
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| 1 |
Ki = 39 nM
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CP0576695
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(3S,6S)-3-benzyl-6-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione
Show/Hide
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C26H33N3O3
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1
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| 1 |
Ki = 39 nM
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CP0466767
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2-(1,4'-bipiperidin-1'-yl)-5-(2-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
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C19H26N4OS
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1
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| 1 |
Ki = 40 nM
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CP0228058
|
diethyl 2,6-dimethyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C27H38N2O5
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1
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| 1 |
Ki = 40 nM
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CP0379582
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2-(1,4'-bipiperidin-1'-yl)-5-(4-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C19H26N4OS
|
1
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| 1 |
Ki = 40.1 nM
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CP0535855
|
1-[2-(4-methoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C13H19NO
|
1
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| 1 |
Ki = 41 nM
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CP0095052
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)pyridin-2-ol
Show/Hide
|
C21H25N5OS
|
1
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| 1 |
Ki = 42 nM
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CP0282258
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-3-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C21H24FN5S
|
1
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| 1 |
Ki = 42 nM
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CP0552647
|
[2-(4-cyanophenyl)-5-methyl-1,3-thiazol-4-yl] 4-piperidin-1-ylpiperidine-1-carboxylate
Show/Hide
|
C22H26N4O2S
|
1
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| 1 |
Ki = 42 nM
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CP0435627
|
2-chloro-7-[(4-chlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H27Cl2N5
|
1
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| 1 |
Ki = 42 nM
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CP0480912
|
3-methyl-1-(5-naphthalen-2-yloxypentyl)piperidine
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 42.3 nM
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CP0527645
|
3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)benzonitrile
Show/Hide
|
C19H23N5S
|
1
|
| 1 |
Ki = 42.6 nM
|
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CP0891660
|
3-(1H-Imidazol-4-yl)propyl N-Benzyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C19H27BrN4S
|
1
|
| 1 |
Ki = 42.66 nM
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CP0488555
|
(2S)-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylamino]propanamide
Show/Hide
|
C18H29N3O2
|
1
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| 1 |
Ki = 42.66 nM
|
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CP0382236
|
N,N-dimethyl-4-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]aniline
Show/Hide
|
C15H24N2
|
1
|
| 1 |
Ki = 43 nM
|
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CP0517392
|
1-(3-(4-(2-fluoroethyl)phenoxy)propyl)piperidine
Show/Hide
|
C16H24FNO
|
1
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| 1 |
Ki = 43 nM
|
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CP0430408
|
(S)-3-(1H-imidazol-4-yl)propyl octan-2-ylcarbamate
Show/Hide
|
C15H27N3O2
|
1
|
| 1 |
Ki = 43 nM
|
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CP0463014
|
6-(2-methoxypyridin-4-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 43 nM
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|
|
CP0478170
|
4-methyl-1-(5-naphthalen-1-yloxypentyl)piperidine
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 43.3 nM
|
|
|
|
CP0073734
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-4-yl)thiazolo[4,5-c]pyridine
Show/Hide
|
C21H24FN5S
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0487150
|
2-(4-chlorophenyl)-5-methyl-4-(2-piperidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0541202
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)-2-fluorobenzonitrile
Show/Hide
|
C23H24FN5S
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0099745
|
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
Show/Hide
|
C16H18N2O2
|
2
|
| 1 |
Ki = 46 nM
|
|
|
| 2 |
Ki = 224 nM
|
|
|
|
CP0402790
|
3-methyl-1-[4-[4-(2-methylbutan-2-yl)phenoxy]butyl]piperidine;oxalic acid
Show/Hide
|
C23H37NO5
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0868684
|
3-(1H-Imidazol-4-yl)propyl N-Butyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C16H29BrN4S
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0397760
|
tert-butyl 5-methyl-2,4-dioxo-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-1-carboxylate
Show/Hide
|
C25H35N3O5
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0525393
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-pyridin-2-yl-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C21H25N5O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0552646
|
5-methyl-2-phenyl-4-(2-pyrrolidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C16H20N2OS
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0520047
|
3-methyl-1-(6-naphthalen-1-yloxyhexyl)piperidine
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 47.6 nM
|
|
|
|
CP0167796
|
1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)-3-cyclopentylurea
Show/Hide
|
C18H30N6OS
|
1
|
| 1 |
Ki = 48.6 nM
|
|
|
|
CP0871058
|
1-[3-(3-(3-Methoxyphenoxy)propoxy)propyl]-3-methylpiperidine hydrogen oxalate
Show/Hide
|
C21H33NO7
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0525292
|
2-(1,4'-bipiperidin-1'-yl)-5-(3-chlorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H23ClN4S
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0378542
|
2-(1,4'-bipiperidin-1'-yl)-5-(3,5-difluorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H22F2N4S
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0951221
|
5-(4-(3-(Piperidin-1-yl)propoxy)benzyl)thiazolidine-2,4-dione
Show/Hide
|
C18H24N2O3S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0565358
|
tert-butyl 2,4-dioxo-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrimidine-1-carboxylate
Show/Hide
|
C24H33N3O5
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0850329
|
1-[3-(3-(4-tert-Butylphenoxy)propoxy)propyl]-3-methyl piperidine hydrogen oxalate
Show/Hide
|
C24H39NO6
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0544075
|
2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0480910
|
1-(6-naphthalen-1-yloxyhexyl)piperidine
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 52.9 nM
|
|
|
|
CP0376957
|
N-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]acetamide
Show/Hide
|
C18H25N5OS
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0390198
|
1-(5-naphthalen-2-yloxypentyl)piperidine
Show/Hide
|
C20H27NO
|
1
|
| 1 |
Ki = 53.5 nM
|
|
|
|
CP0425443
|
US8796297, 2
Show/Hide
|
C8H15N5
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0477336
|
[2-(4-chlorophenyl)-5-methyl-1,3-thiazol-4-yl] 4-piperidin-1-ylpiperidine-1-carboxylate
Show/Hide
|
C21H26ClN3O2S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0477179
|
2-chloro-7-[(2,6-dichlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H26Cl3N5
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0569226
|
3-methyl-1-(6-naphthalen-2-yloxyhexyl)piperidine
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 55.9 nM
|
|
|
|
CP0435965
|
5-methyl-4-(2-piperidin-1-ylethoxy)-2-pyridin-4-yl-1,3-thiazole
Show/Hide
|
C16H21N3OS
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0564018
|
1-(5-naphthalen-2-yloxypentyl)azepane
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 57.3 nM
|
|
|
|
CP0391370
|
3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]benzaldehyde
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0401265
|
4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)phenol
Show/Hide
|
C22H26N4OS
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0527646
|
2-(1,4'-bipiperidin-1'-yl)-5-m-tolyl-1,3,4-thiadiazole
Show/Hide
|
C19H26N4S
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0398376
|
(2R,4S)-4-(3-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0483365
|
(2R,4R)-4-(2-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0266720
|
6-methyl-2-[4-[6-(3-methylpiperidin-1-yl)hexoxy]phenyl]chromen-4-one
Show/Hide
|
C28H35NO3
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0434002
|
diethyl 2,6-dimethyl-4-[4-(4-pyrrolidin-1-ylbutoxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C27H38N2O5
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0381034
|
4-(1-cyclohexylethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 60.26 nM
|
|
|
|
CP0468445
|
US8796297, 6
Show/Hide
|
C7H13N5
|
1
|
| 1 |
Ki = 61.7 nM
|
|
|
|
CP0480911
|
1-(6-naphthalen-2-yloxyhexyl)piperidine
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 61.8 nM
|
|
|
|
CP0485073
|
1-(3-(2-(3-methoxyphenoxy)ethoxy)propyl)azepane
Show/Hide
|
C18H29NO3
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0437302
|
2-(1,4'-bipiperidin-1'-yl)-5-(3-fluorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H23FN4S
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0230695
|
2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C21H24FN5S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0520548
|
5-phenyl-2-(4-(piperidin-1-yl)butyl)oxazole
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0218637
|
4-(4-methylpiperazin-1-yl)-7-thiophen-3-ylquinazolin-2-amine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0397757
|
5-methyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-1H-pyrimidine-2,4-dione
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0047136
|
(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0253732
|
2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-yl)thiazolo[4,5-c]pyridine
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0454761
|
5-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]-1,3-dihydroindol-2-one
Show/Hide
|
C20H25N5OS
|
1
|
| 1 |
Ki = 64.4 nM
|
|
|
|
CP0382233
|
(2S)-1-[2-(3-methoxyphenyl)ethyl]-2-methylpyrrolidine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0379948
|
1-(4-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)phenyl)ethanone
Show/Hide
|
C20H26N4OS
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0042243
|
5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)pyrazin-2-amine
Show/Hide
|
C20H25N7S
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0385794
|
US8796297, 23
Show/Hide
|
C11H17N5
|
1
|
| 1 |
Ki = 67.6 nM
|
|
|
|
CP0917434
|
3-(1H-imidazol-4-yl)propyl N-tert-butyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C16H29BrN4S
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0943377
|
1-(4-(4-(tert-Pentyl)phenoxy)butyl)azepane hydrogen oxalate
Show/Hide
|
C23H37NO5
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0496745
|
2-(1,4'-bipiperidin-1'-yl)-5-(2-chlorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H23ClN4S
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0551853
|
1-(6-naphthalen-1-yloxyhexyl)azepane
Show/Hide
|
C22H31NO
|
2
|
| 1 |
Ki = 69 nM
|
|
|
| 2 |
Ki = 69.3 nM
|
|
|
|
CP0162934
|
1-(6-naphthalen-2-yloxyhexyl)azepane
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 69.3 nM
|
|
|
|
CP0454318
|
4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C12H18N2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0503211
|
6-(6-fluoropyridin-3-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C21H24FN5O
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0441304
|
4-cyclohexyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C14H21N5
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
|
CP0503639
|
2-(1,4'-bipiperidin-1'-yl)-5-(3,5-dichlorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H22Cl2N4S
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0552652
|
5-methyl-2-pyrazin-2-yl-4-[[4-(pyrrolidin-1-ylmethyl)phenyl]methoxy]-1,3-thiazole
Show/Hide
|
C20H22N4OS
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0544850
|
US8796297, 12
Show/Hide
|
C16H21N5
|
1
|
| 1 |
Ki = 72.4 nM
|
|
|
|
CP0473928
|
2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-amine
Show/Hide
|
C16H23N5S
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0543964
|
(3S)-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione
Show/Hide
|
C19H27N3O3
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0502554
|
4-(1-cyclohexylethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0411110
|
5,5-diphenyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]imidazolidine-2,4-dione
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0542571
|
oxalic acid;1-[5-(3-phenylphenoxy)pentyl]piperidine
Show/Hide
|
C24H31NO5
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0489820
|
azetidin-1-yl-[3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]phenyl]methanone
Show/Hide
|
C22H29N5OS
|
1
|
| 1 |
Ki = 78.9 nM
|
|
|
|
CP0534154
|
2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-amine
Show/Hide
|
C16H23N5S
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0077932
|
6-(4-methoxyquinolin-8-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0463015
|
6-(6-ethylpyridin-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C23H29N5O
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0390893
|
1-(3-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)phenyl)ethanone
Show/Hide
|
C24H28N4OS
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0428882
|
(2R,4S)-4-(3-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0523989
|
2-(1,4'-bipiperidin-1'-yl)-5-phenyl-1,3,4-thiadiazole
Show/Hide
|
C18H24N4S
|
1
|
| 1 |
Ki = 80.1 nM
|
|
|
|
CP0457788
|
1-[2-(4-methylphenyl)ethyl]pyrrolidine
Show/Hide
|
C13H19N
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0502233
|
4-benzyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H17N5
|
1
|
| 1 |
Ki = 81.28 nM
|
|
|
|
CP0423901
|
2-methyl-6-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]chromen-4-one
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
Ki = 82.8 nM
|
|
|
|
CP0490811
|
diethyl 2,6-dimethyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C26H36N2O5
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0119046
|
1-[6-(4-ethylphenoxy)hexyl]azepane
Show/Hide
|
C20H33NO
|
1
|
| 1 |
Ki = 84.3 nM
|
|
|
|
CP0435969
|
5-[5-methyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazol-2-yl]-3H-2-benzofuran-1-one
Show/Hide
|
C20H24N2O3S
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0554672
|
4-methyl-1-[5-(4-phenylphenoxy)pentyl]piperidine;oxalic acid
Show/Hide
|
C25H33NO5
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0500526
|
4-(cyclopentylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C14H21N5
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0554669
|
oxalic acid;1-[6-(4-phenylphenoxy)hexyl]piperidine
Show/Hide
|
C25H33NO5
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0404791
|
4-methyl-1-(6-naphthalen-2-yloxyhexyl)piperidine
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 92.1 nM
|
|
|
|
CP0042241
|
2-(1,4'-bipiperidin-1'-yl)-6-(6-methoxypyridin-3-yl)thiazolo[4,5-c]pyridine
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0527813
|
(2R,4S)-4-(3-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0503856
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-pyridin-3-yl-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C21H25N5O
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0404792
|
4-methyl-1-(5-naphthalen-2-yloxypentyl)piperidine
Show/Hide
|
C21H29NO
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0486791
|
2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]phenol
Show/Hide
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C13H19NO
|
1
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| 1 |
Ki = 96 nM
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CP0510854
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(2R)-2-methyl-1-[2-(4-nitrophenyl)ethyl]pyrrolidine
Show/Hide
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C13H18N2O2
|
1
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| 1 |
Ki = 96 nM
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CP0441269
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4-heptyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
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C15H25N5
|
1
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| 1 |
Ki = 97.72 nM
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CP0335770
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7-(furan-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
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C17H19N5O
|
1
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| 1 |
Ki = 98 nM
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CP0477337
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[2-(3-chlorophenyl)-5-methyl-1,3-thiazol-4-yl] 4-piperidin-1-ylpiperidine-1-carboxylate
Show/Hide
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C21H26ClN3O2S
|
1
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| 1 |
Ki = 98 nM
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CP0459810
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5-methoxy-2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]-1H-indole
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C16H22N2O
|
1
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| 1 |
Ki = 100 nM
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CP0475437
|
4-(4-cyclopentylpiperazin-1-yl)quinazoline
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C17H22N4
|
1
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| 1 |
Ki = 100 nM
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CP0121280
|
7-[2-[2-(3-chlorophenyl)ethylamino]ethyl]quinolin-2-amine
Show/Hide
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C19H20ClN3
|
1
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| 1 |
Ki < 100 nM
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CP0513322
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5-methyl-2-pyridin-4-yl-4-(2-pyrrolidin-1-ylethoxy)-1,3-thiazole
Show/Hide
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C15H19N3OS
|
1
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| 1 |
Ki = 100 nM
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CP0474962
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3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)-N-methylpropan-1-amine
Show/Hide
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C22H21FN4O
|
1
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| 1 |
Ki = 101 nM
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CP0437303
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2-(1,4'-bipiperidin-1'-yl)-5-(pyrimidin-2-yl)-1,3,4-thiadiazole
Show/Hide
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C16H22N6S
|
1
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| 1 |
Ki = 103 nM
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CP0290723
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2-(1,4'-bipiperidin-1'-yl)-6-(6-methylpyridin-3-yl)thiazolo[4,5-c]pyridine
Show/Hide
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C22H27N5S
|
1
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| 1 |
Ki = 104 nM
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CP0500525
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1-[3-(1H-imidazol-5-yl)propyl]-4-pentyltriazole
Show/Hide
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C13H21N5
|
1
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| 1 |
Ki = 104.71 nM
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CP0289053
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2-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)-1,2,3,4-tetrahydroisoquinoline
Show/Hide
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C30H27FN4O
|
1
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| 1 |
Ki = 107 nM
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CP0205481
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5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]-1,3-dihydroindol-2-one
Show/Hide
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C24H27N5O2
|
1
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| 1 |
Ki = 109 nM
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CP0457789
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(2S)-2-methyl-1-(2-thiophen-2-ylethyl)pyrrolidine
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C11H17NS
|
1
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| 1 |
Ki = 110 nM
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CP0479121
|
5-(4-(piperidin-1-yl)butyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
Show/Hide
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C16H22N4O
|
1
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| 1 |
Ki = 110 nM
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CP0552649
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N,N-dimethyl-3-[(5-methyl-2-pyridin-4-yl-1,3-thiazol-4-yl)oxy]propan-1-amine
Show/Hide
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C14H19N3OS
|
1
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| 1 |
Ki = 110 nM
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CP0262404
|
cyclopropyl-[4-[3-(4-phenylpiperazin-1-yl)propoxy]phenyl]methanone
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C23H28N2O2
|
1
|
| 1 |
Ki = 111 nM
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CP0502583
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4-(cycloheptylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
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C16H25N5
|
1
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| 1 |
Ki = 112.2 nM
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CP0502556
|
4-(cyclopentylmethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
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C13H19N5
|
1
|
| 1 |
Ki = 114.82 nM
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CP0532789
|
1-[4-[4-(4-pyridin-4-ylpiperazin-1-yl)butoxy]phenyl]ethanone
Show/Hide
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C21H27N3O2
|
1
|
| 1 |
Ki = 115 nM
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CP0420700
|
oxalic acid;1-[5-(3-phenylphenoxy)pentyl]azepane
Show/Hide
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C25H33NO5
|
1
|
| 1 |
Ki = 115 nM
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CP0130340
|
6-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
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C24H28N4O3
|
1
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| 1 |
Ki = 117 nM
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CP0205482
|
7-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C24H26N6O2
|
1
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| 1 |
Ki = 119 nM
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CP0398380
|
(2R,4S)-N,N-dimethyl-4-(2-methylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
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C19H24ClN
|
1
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| 1 |
Ki = 120 nM
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CP0862786
|
1-(4-(4-(tert-pentyl)phenoxy)butyl)-4-(pyridin-4-yl)piperazine
Show/Hide
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C24H35N3O
|
1
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| 1 |
Ki = 120 nM
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CP0920208
|
1-((1-(3-(piperidin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methyl)piperidine fumarate salt
Show/Hide
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C20H33N5O4
|
1
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| 1 |
Ki = 120.23 nM
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CP0435629
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7-(2-morpholin-4-ylethyl)-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C22H35N7O
|
1
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| 1 |
Ki = 121 nM
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CP0437990
|
oxalic acid;1-[6-(3-phenylphenoxy)hexyl]piperidine
Show/Hide
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C25H33NO5
|
1
|
| 1 |
Ki = 122 nM
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CP0540165
|
2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-b]pyridine
Show/Hide
|
C16H21ClN4S
|
1
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| 1 |
Ki = 125 nM
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CP0503562
|
4-(cyclohexylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 125.89 nM
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CP0430728
|
4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)benzonitrile
Show/Hide
|
C23H25N5S
|
1
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| 1 |
Ki = 126 nM
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CP0520048
|
4-methyl-1-(6-naphthalen-1-yloxyhexyl)piperidine
Show/Hide
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C22H31NO
|
1
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| 1 |
Ki = 126 nM
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CP0455322
|
2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridine
Show/Hide
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C16H22N4S
|
1
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| 1 |
Ki = 128 nM
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CP0345088
|
1-[7-(4-chlorophenoxy)heptyl]piperidine
Show/Hide
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C18H28ClNO
|
1
|
| 1 |
Ki = 128 nM
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CP0552650
|
5-methyl-4-(3-piperidin-1-ylpropoxy)-2-pyridin-4-yl-1,3-thiazole
Show/Hide
|
C17H23N3OS
|
1
|
| 1 |
Ki = 130 nM
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CP0462545
|
2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1H-indole
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 132 nM
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CP0044000
|
2-(1,4'-bipiperidin-1'-yl)-6-(6-methylpyridin-3-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5S
|
1
|
| 1 |
Ki = 133 nM
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CP0180438
|
1-[5-(4-chlorophenoxy)pentyl]-3-methylpiperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 133 nM
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CP0534152
|
2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridine
Show/Hide
|
C16H22N4S
|
1
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| 1 |
Ki = 139 nM
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CP0457792
|
4-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C12H18N2
|
1
|
| 1 |
Ki = 140 nM
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CP0401264
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2-(1,4'-bipiperidin-1'-yl)-6-(3-methoxyphenyl)thiazolo[4,5-b]pyridine
Show/Hide
|
C23H28N4OS
|
1
|
| 1 |
Ki = 140 nM
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CP0943378
|
1-(4-(4-(tert-Pentyl)phenoxy)butyl)piperidine hydrogen oxalate
Show/Hide
|
C22H35NO5
|
1
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| 1 |
Ki = 140 nM
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CP0502841
|
2-(1,4'-bipiperidin-1'-yl)-6-bromothiazolo[4,5-b]pyrazine
Show/Hide
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C16H21BrN4S
|
1
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| 1 |
Ki = 141 nM
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CP0525394
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-[6-(trifluoromethyl)pyridin-2-yl]-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H24F3N5O
|
1
|
| 1 |
Ki = 143 nM
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CP0659150
|
(R)-7-isopropyl-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C15H22N6
|
1
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| 1 |
Ki = 144.54 nM
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CP0503209
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6-[(2R)-2-methylpyrrolidin-1-yl]-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C21H31N5O
|
1
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| 1 |
Ki = 150 nM
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CP0443907
|
oxalic acid;1-[6-(4-phenylphenoxy)hexyl]azepane
Show/Hide
|
C26H35NO5
|
1
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| 1 |
Ki = 151 nM
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CP0331875
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7-cyclopentyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C16H22N6
|
1
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| 1 |
Ki = 151.36 nM
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CP0338988
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7-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]-3H-quinazolin-4-one
Show/Hide
|
C24H26N6O2
|
1
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| 1 |
Ki = 153 nM
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CP0899613
|
7-cyclopropyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
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C15H19N5
|
1
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| 1 |
Ki = 154.88 nM
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CP0542570
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4-methyl-1-[5-(3-phenylphenoxy)pentyl]piperidine;oxalic acid
Show/Hide
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C25H33NO5
|
1
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| 1 |
Ki = 157 nM
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CP0539618
|
US8796297, 19
Show/Hide
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C17H21N5
|
1
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| 1 |
Ki = 158 nM
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CP0574206
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(3R)-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione
Show/Hide
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C19H27N3O3
|
1
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| 1 |
Ki = 158.3 nM
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CP0744165
|
7-cyclopentyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H23N5
|
1
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| 1 |
Ki = 158.49 nM
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CP0429652
|
5-(3-piperidin-1-ylpropoxy)-2,3-dihydroinden-1-one
Show/Hide
|
C17H23NO2
|
1
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| 1 |
Ki = 159 nM
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CP0551924
|
4-methyl-1-[6-(3-phenylphenoxy)hexyl]piperidine;oxalic acid
Show/Hide
|
C26H35NO5
|
1
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| 1 |
Ki = 159 nM
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CP0574207
|
(3S,6S)-3-methyl-6-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-2,5-dione
Show/Hide
|
C20H29N3O3
|
1
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| 1 |
Ki = 159 nM
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CP0125672
|
2-[4-[6-(azepan-1-yl)hexoxy]phenyl]-6-methylchromen-4-one
Show/Hide
|
C28H35NO3
|
1
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| 1 |
Ki = 159.8 nM
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CP0408042
|
2-(1,4'-bipiperidin-1'-yl)-5-(4-chlorophenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H23ClN4S
|
1
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| 1 |
Ki = 161 nM
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CP0437304
|
2-(4-ethylpiperazin-1-yl)-5-(4-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C15H20N4OS
|
1
|
| 1 |
Ki = 161.8 nM
|
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CP0411385
|
US8796297, 21
Show/Hide
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C17H23N5
|
1
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| 1 |
Ki = 162 nM
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CP0528600
|
2-(1,4'-bipiperidin-1'-yl)-5-p-tolyl-1,3,4-thiadiazole
Show/Hide
|
C19H26N4S
|
1
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| 1 |
Ki = 163 nM
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CP0457929
|
2-(4-chlorophenyl)-5-ethyl-4-(3-pyrrolidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C18H23ClN2OS
|
1
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| 1 |
Ki = 170 nM
|
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CP0541064
|
1-[6-(3-chlorophenoxy)hexyl]-3-methylpiperidine;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
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| 1 |
Ki = 174 nM
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CP0150249
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1-[6-(3-chlorophenoxy)hexyl]-3-methylpiperidine
Show/Hide
|
C18H28ClNO
|
1
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| 1 |
Ki = 174 nM
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CP0861813
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(R)-7-cyclopropyl-4-(3-(methylamino)pyrrolidin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H21N5
|
1
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| 1 |
Ki = 177.83 nM
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CP0429153
|
US8796297, 10
Show/Hide
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C9H17N5
|
1
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| 1 |
Ki = 178 nM
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CP0569753
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1-[7-(4-chlorophenoxy)heptyl]-3-methylpiperidine;oxalic acid
Show/Hide
|
C21H32ClNO5
|
1
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| 1 |
Ki = 180 nM
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CP0162933
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1-[7-(4-chlorophenoxy)heptyl]-3-methylpiperidine
Show/Hide
|
C19H30ClNO
|
1
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| 1 |
Ki = 180 nM
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CP0098830
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1-[6-(4-ethylphenoxy)hexyl]-4-methylpiperidine
Show/Hide
|
C20H33NO
|
1
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| 1 |
Ki = 181.5 nM
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CP0379583
|
2-(4-cyclopentylpiperazin-1-yl)-5-(4-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C18H24N4OS
|
1
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| 1 |
Ki = 182.3 nM
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CP0220828
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4-N-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C13H22N6
|
1
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| 1 |
Ki = 186.21 nM
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CP0373662
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2-(3-(piperidin-1-yl)propylthio)-5-(pyridin-4-yl)-1,3,4-oxadiazole
Show/Hide
|
C15H20N4OS
|
1
|
| 1 |
Ki = 187 nM
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CP0146662
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7-(furan-3-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki = 188 nM
|
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CP0474373
|
1-[6-(4-chlorophenoxy)hexyl]-4-methylpiperidine;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 189 nM
|
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CP0430360
|
1-[6-(4-chlorophenoxy)hexyl]-4-methylpiperidine
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 189 nM
|
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CP0454317
|
5-(2-pyrrolidin-1-ylethyl)-1,2-thiazole
Show/Hide
|
C9H14N2S
|
1
|
| 1 |
Ki = 190 nM
|
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CP0386626
|
(2S,4S)-4-(2-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 190 nM
|
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CP0552651
|
4-[5-methyl-4-[[4-(pyrrolidin-1-ylmethyl)phenyl]methoxy]-1,3-thiazol-2-yl]benzonitrile
Show/Hide
|
C23H23N3OS
|
1
|
| 1 |
Ki = 190 nM
|
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CP0503455
|
4-tert-butyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C12H19N5
|
1
|
| 1 |
Ki = 190.55 nM
|
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CP0466087
|
2-(1,4'-bipiperidin-1'-yl)-5-(1H-pyrazol-4-yl)-1,3,4-thiadiazole
Show/Hide
|
C15H22N6S
|
1
|
| 1 |
Ki = 192 nM
|
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CP0564570
|
1-[4-[3-(4-pyridin-3-ylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 192 nM
|
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CP0549127
|
N,N-dimethyl-3-[5-(4-piperidin-1-ylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]benzamide
Show/Hide
|
C21H29N5OS
|
1
|
| 1 |
Ki = 192.4 nM
|
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CP0495137
|
6-(2-methylpyridin-4-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
Ki = 196 nM
|
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|
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CP0462549
|
2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C12H18N2
|
1
|
| 1 |
Ki = 200 nM
|
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|
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CP0502022
|
1-[2-(3-methylphenyl)ethyl]pyrrolidine
Show/Hide
|
C13H19N
|
1
|
| 1 |
Ki = 200 nM
|
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|
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CP0398760
|
(2S,4R)-N,N-dimethyl-4-(3-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C24H26ClN
|
1
|
| 1 |
Ki = 200 nM
|
|
|
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CP0476818
|
5-methyl-2-phenyl-4-(2-piperidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
Ki = 200 nM
|
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|
CP0563121
|
2-(4-chlorophenyl)-5-ethyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C19H25ClN2OS
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0425165
|
1-[7-(4-chlorophenoxy)heptyl]azepane;oxalic acid
Show/Hide
|
C21H32ClNO5
|
1
|
| 1 |
Ki = 203 nM
|
|
|
|
CP0352200
|
1-[7-(4-chlorophenoxy)heptyl]azepane
Show/Hide
|
C19H30ClNO
|
1
|
| 1 |
Ki = 203 nM
|
|
|
|
CP0562134
|
1-[6-(4-chlorophenoxy)hexyl]-3-methylpiperidine;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0569601
|
5-(2-piperidin-1-ylethoxy)-2,3-dihydroinden-1-one
Show/Hide
|
C16H21NO2
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0249394
|
1-[6-(4-chlorophenoxy)hexyl]-3-methylpiperidine
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0388452
|
4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)phenol
Show/Hide
|
C22H26N4OS
|
1
|
| 1 |
Ki = 213 nM
|
|
|
|
CP0659153
|
7-ethyl-4-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
Ki = 213.8 nM
|
|
|
|
CP0917026
|
7-ethyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0462546
|
2-(2-pyrrolidin-1-ylethyl)-1H-indole
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0575289
|
(3S,6S)-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-6-propan-2-ylpiperazine-2,5-dione
Show/Hide
|
C22H33N3O3
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0487149
|
5-methyl-4-[(1-methylpiperidin-4-yl)methoxy]-2-phenyl-1,3-thiazole
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0119043
|
6-methyl-2-[4-(6-piperidin-1-ylhexoxy)phenyl]chromen-4-one
Show/Hide
|
C27H33NO3
|
1
|
| 1 |
Ki = 228.2 nM
|
|
|
|
CP0440957
|
5-ethyl-2-(2-pyrrolidin-1-ylethyl)pyridine
Show/Hide
|
C13H20N2
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0502021
|
5-methoxy-2-(2-pyrrolidin-1-ylethyl)-1H-indole
Show/Hide
|
C15H20N2O
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0455337
|
2-(1,4'-bipiperidin-1'-yl)-6-(3-methoxyphenyl)thiazolo[4,5-c]pyridine
Show/Hide
|
C23H28N4OS
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0398752
|
(2R,4S)-N,N-dimethyl-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0542186
|
(2S,4R)-N,N-dimethyl-4-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0463011
|
N-[4-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]phenyl]acetamide
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
Ki = 233 nM
|
|
|
|
CP0420469
|
1-[6-(4-chlorophenoxy)hexyl]azepane;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0273509
|
1-[6-(4-chlorophenoxy)hexyl]azepane
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0503855
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-[4-(trifluoromethyl)phenyl]-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C23H25F3N4O
|
1
|
| 1 |
Ki = 238 nM
|
|
|
|
CP0953726
|
4-Methyl-1-(4-(4-(tert-pentyl)phenoxy)butyl)piperidine hydrogen oxalate
Show/Hide
|
C23H37NO5
|
1
|
| 1 |
Ki = 238 nM
|
|
|
|
CP0525391
|
[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]phenyl]methanol
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 249 nM
|
|
|
|
CP0503857
|
5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]pyridine-3-carbonitrile
Show/Hide
|
C22H24N6O
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0385046
|
1-[6-(3-chlorophenoxy)hexyl]piperidine;oxalic acid
Show/Hide
|
C19H28ClNO5
|
1
|
| 1 |
Ki = 255 nM
|
|
|
|
CP0150200
|
1-[6-(3-chlorophenoxy)hexyl]piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 255 nM
|
|
|
|
CP0385078
|
US8796297, 3
Show/Hide
|
C9H17N5
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0486789
|
1-[2-(3-methoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0416907
|
6-(1,3-dihydroisoindol-2-yl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0486617
|
1-[6-(4-chlorophenoxy)hexyl]piperidine;oxalic acid
Show/Hide
|
C19H28ClNO5
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0272658
|
1-[6-(4-chlorophenoxy)hexyl]piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0565088
|
4-methyl-1-[6-(4-phenylphenoxy)hexyl]piperidine;oxalic acid
Show/Hide
|
C26H35NO5
|
1
|
| 1 |
Ki = 266 nM
|
|
|
|
CP0502024
|
2-(2-pyrrolidin-1-ylethyl)phenol
Show/Hide
|
C12H17NO
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0392131
|
5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]pyridin-2-amine
Show/Hide
|
C21H26N6O
|
1
|
| 1 |
Ki = 278 nM
|
|
|
|
CP0563120
|
3-[[2-(4-chlorophenyl)-5-methyl-1,3-thiazol-4-yl]oxy]-N,N-dimethylpropan-1-amine
Show/Hide
|
C15H19ClN2OS
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0525392
|
4-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]benzamide
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 288 nM
|
|
|
|
CP0420470
|
1-[6-(3-chlorophenoxy)hexyl]azepane;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 293 nM
|
|
|
|
CP0549242
|
1-[6-(3-chlorophenoxy)hexyl]azepane
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 293 nM
|
|
|
|
CP0457791
|
5-ethyl-2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C14H22N2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0510855
|
3-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C12H18N2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0552648
|
2-(3-chlorophenyl)-5-methyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C18H23ClN2OS
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0546588
|
US8796297, 20
Show/Hide
|
C9H15N5
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0412803
|
6-(3-piperidin-1-ylpropoxy)-2,3-dihydroinden-1-one
Show/Hide
|
C17H23NO2
|
1
|
| 1 |
Ki = 304 nM
|
|
|
|
CP0528102
|
1-[4-[3-(4-pyridin-2-ylpiperazin-1-yl)propoxy]phenyl]ethanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 315 nM
|
|
|
|
CP0468440
|
US8796297, 8
Show/Hide
|
C8H15N5
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0202795
|
2-(diaminomethylideneamino)ethyl carbamimidothioate
Show/Hide
|
C4H11N5S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0397748
|
4-[1-[2-chloro-7-(2-morpholin-4-ylethyl)pyrrolo[2,3-d]pyrimidin-4-yl]piperidin-4-yl]morpholine
Show/Hide
|
C21H31ClN6O2
|
1
|
| 1 |
Ki = 317 nM
|
|
|
|
CP0549126
|
4-(cyclohexylmethyl)-1-[4-(1H-imidazol-5-yl)butyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0462746
|
US8796297, 24
Show/Hide
|
C9H15N5
|
1
|
| 1 |
Ki = 324 nM
|
|
|
|
CP0744166
|
7-cyclopentyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H23N5
|
1
|
| 1 |
Ki = 331.13 nM
|
|
|
|
CP0569752
|
1-[7-(3-chlorophenoxy)heptyl]piperidine;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 333 nM
|
|
|
|
CP0273510
|
1-[7-(3-chlorophenoxy)heptyl]piperidine
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 333 nM
|
|
|
|
CP0505151
|
1-[2-(2-methoxyphenyl)ethyl]pyrrolidine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0525663
|
2-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]pyridine
Show/Hide
|
C12H18N2
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0569602
|
5-(2-pyrrolidin-1-ylethoxy)-2,3-dihydroinden-1-one
Show/Hide
|
C15H19NO2
|
1
|
| 1 |
Ki = 345 nM
|
|
|
|
CP0232365
|
4-(2-pyrrolidin-1-ylethyl)pyridine
Show/Hide
|
C11H16N2
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0392129
|
2-(4-piperidin-1-ylpiperidin-1-yl)-6-(1-pyrimidin-2-ylpiperidin-4-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C25H33N7O
|
1
|
| 1 |
Ki = 357 nM
|
|
|
|
CP0440956
|
1-[2-(4-nitrophenyl)ethyl]pyrrolidine
Show/Hide
|
C12H16N2O2
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0539524
|
6-ethenyl-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C18H24N4O
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0486618
|
1-[5-(4-chlorophenoxy)pentyl]azepane;oxalic acid
Show/Hide
|
C19H28ClNO5
|
1
|
| 1 |
Ki = 371 nM
|
|
|
|
CP0273501
|
1-[5-(4-chlorophenoxy)pentyl]azepane
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 371 nM
|
|
|
|
CP0397749
|
4-[1-[7-(2-morpholin-4-ylethyl)pyrrolo[2,3-d]pyrimidin-4-yl]piperidin-4-yl]morpholine
Show/Hide
|
C21H32N6O2
|
1
|
| 1 |
Ki = 374 nM
|
|
|
|
CP0562883
|
1-[4-[3-(4-pyridin-2-ylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 377 nM
|
|
|
|
CP0463010
|
2-methyl-1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]phenyl]propan-1-ol
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 379 nM
|
|
|
|
CP0435971
|
5-ethyl-2-phenyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C19H26N2OS
|
1
|
| 1 |
Ki = 380 nM
|
|
|
|
CP0469139
|
1-[[1-[3-(1H-imidazol-5-yl)propyl]triazol-4-yl]methyl]piperidine
Show/Hide
|
C14H22N6
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0502555
|
4-benzyl-1-[2-(1H-imidazol-5-yl)ethyl]triazole
Show/Hide
|
C14H15N5
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0502023
|
1-[2-(2,4,6-trimethylphenyl)ethyl]pyrrolidine
Show/Hide
|
C15H23N
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0398381
|
(2S,4R)-N,N-dimethyl-4-(2-methylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H24ClN
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0476819
|
5-methyl-2-pyridin-4-yl-4-(3-pyrrolidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C16H21N3OS
|
1
|
| 1 |
Ki = 410 nM
|
|
|
|
CP0385094
|
1-[6-(3-chlorophenoxy)hexyl]-4-methylpiperidine;oxalic acid
Show/Hide
|
C20H30ClNO5
|
1
|
| 1 |
Ki = 412 nM
|
|
|
|
CP0273511
|
1-[6-(3-chlorophenoxy)hexyl]-4-methylpiperidine
Show/Hide
|
C18H28ClNO
|
1
|
| 1 |
Ki = 412 nM
|
|
|
|
CP0262528
|
diethyl 2,6-dimethyl-4-[4-(5-pyrrolidin-1-ylpentoxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C28H40N2O5
|
1
|
| 1 |
Ki = 425 nM
|
|
|
|
CP0538132
|
1-[5-(4-chlorophenoxy)pentyl]piperidine;oxalic acid
Show/Hide
|
C18H26ClNO5
|
1
|
| 1 |
Ki = 427 nM
|
|
|
|
CP0224672
|
1-[5-(4-chlorophenoxy)pentyl]piperidine
Show/Hide
|
C16H24ClNO
|
1
|
| 1 |
Ki = 427 nM
|
|
|
|
CP0398355
|
(2S,4R)-4-cyclooctyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C20H32ClN
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0566449
|
2-(3-chlorophenyl)-5-methyl-4-(3-pyrrolidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0352198
|
1-[7-(3-chlorophenoxy)heptyl]-3-methylpiperidine
Show/Hide
|
C19H30ClNO
|
1
|
| 1 |
Ki = 446 nM
|
|
|
|
CP0554358
|
2-(4-chlorophenyl)-5-methyl-4-(3-pyrrolidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0560745
|
4-[5-methyl-4-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]-1,3-thiazol-2-yl]benzonitrile
Show/Hide
|
C24H25N3OS
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0388840
|
1-[7-(3-chlorophenoxy)heptyl]-3-methylpiperidine;oxalic acid
Show/Hide
|
C21H32ClNO5
|
1
|
| 1 |
Ki = 466 nM
|
|
|
|
CP0425166
|
1-[7-(4-chlorophenoxy)heptyl]-4-methylpiperidine;oxalic acid
Show/Hide
|
C21H32ClNO5
|
1
|
| 1 |
Ki = 467 nM
|
|
|
|
CP0574674
|
1-[7-(4-chlorophenoxy)heptyl]-4-methylpiperidine
Show/Hide
|
C19H30ClNO
|
1
|
| 1 |
Ki = 467 nM
|
|
|
|
CP0958099
|
1-(4-(4-(tert-pentyl)phenoxy)butyl)-4-(pyridin-2-yl)piperazine
Show/Hide
|
C24H35N3O
|
1
|
| 1 |
Ki = 482 nM
|
|
|
|
CP0503456
|
1-[3-[4-(cyclohexylmethyl)triazol-1-yl]propyl]piperidine
Show/Hide
|
C17H30N4
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0768043
|
7-tert-butyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H23N5
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0470594
|
1-[4-[3-(4-pyridin-3-ylpiperazin-1-yl)propoxy]phenyl]ethanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 499 nM
|
|
|
|
CP0003459
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
Ki = 509 nM
|
|
|
|
CP0477335
|
5-methyl-2-phenyl-4-(3-pyrrolidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C17H22N2OS
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0167934
|
6-[6-(3-methylpiperidin-1-yl)hexoxy]-2-phenyl-2,3-dihydrochromen-4-one
Show/Hide
|
C27H35NO3
|
1
|
| 1 |
Ki = 522.8 nM
|
|
|
|
CP0428878
|
(2R,4S)-4-(4-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 530 nM
|
|
|
|
CP0461101
|
5,5-diphenyl-3-(3-piperidin-1-ylpropyl)imidazolidine-2,4-dione
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 562.34 nM
|
|
|
|
CP0262529
|
diethyl 2,6-dimethyl-4-[4-(5-piperidin-1-ylpentoxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C29H42N2O5
|
1
|
| 1 |
Ki = 565 nM
|
|
|
|
CP0502234
|
4-benzyl-1-[4-(1H-imidazol-5-yl)butyl]triazole
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0392619
|
3-(2-piperidin-1-ylethyl)-[1,2,4]triazolo[1,5-a]benzimidazole
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0552239
|
2-(3-chlorophenyl)-5-methyl-4-(2-piperidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0426629
|
2-(4-methoxyphenyl)-5-(4-(pyrrolidin-1-yl)piperidin-1-yl)-1,3,4-thiadiazole
Show/Hide
|
C18H24N4OS
|
1
|
| 1 |
Ki = 600.9 nM
|
|
|
|
CP0673020
|
(R)-7-ethyl-4-(3-(methylamino)pyrrolidin-1-yl)quinazolin-2-amine
Show/Hide
|
C15H21N5
|
1
|
| 1 |
Ki = 602.56 nM
|
|
|
|
CP0744164
|
7-ethyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 616.6 nM
|
|
|
|
CP0271676
|
7-cyclopropyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H18N6
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0468242
|
2-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-5-(4-methoxyphenyl)-1,3,4-thiadiazole
Show/Hide
|
C16H20N4OS
|
1
|
| 1 |
Ki = 652.6 nM
|
|
|
|
CP0463009
|
N-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]acetamide
Show/Hide
|
C18H25N5O2
|
1
|
| 1 |
Ki = 657 nM
|
|
|
|
CP0428879
|
(2R,4S)-N,N-dimethyl-4-(4-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 680 nM
|
|
|
|
CP0795071
|
2-(4-(4-(4-(tert-pentyl)phenoxy)butyl)piperazin-1-yl)pyrazine
Show/Hide
|
C23H34N4O
|
1
|
| 1 |
Ki = 683 nM
|
|
|
|
CP0673021
|
7-cyclopropyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 691.83 nM
|
|
|
|
CP0558092
|
(2E)-2-benzylidene-6-(2-piperidin-1-ylethoxy)-3H-inden-1-one
Show/Hide
|
C23H25NO2
|
1
|
| 1 |
Ki = 696 nM
|
|
|
|
CP0459651
|
2-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)-2,3-dihydro-1H-benzo[de]isoquinoline
Show/Hide
|
C33H27FN4O
|
1
|
| 1 |
Ki = 713 nM
|
|
|
|
CP0221098
|
7-ethyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C13H18N6
|
1
|
| 1 |
Ki = 776.25 nM
|
|
|
|
CP0378016
|
1-[3-[4-(cyclohexylmethyl)triazol-1-yl]propyl]-4-methylpiperazine
Show/Hide
|
C17H31N5
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0398353
|
(2S,4R)-N,N-dimethyl-4-(3-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0474374
|
1-[5-(4-chlorophenoxy)pentyl]-4-methylpiperidine;oxalic acid
Show/Hide
|
C19H28ClNO5
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0180431
|
1-[5-(4-chlorophenoxy)pentyl]-4-methylpiperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0538119
|
1-[7-(3-chlorophenoxy)heptyl]-4-methylpiperidine;oxalic acid
Show/Hide
|
C21H32ClNO5
|
1
|
| 1 |
Ki = 805 nM
|
|
|
|
CP0528544
|
1-[7-(3-chlorophenoxy)heptyl]-4-methylpiperidine
Show/Hide
|
C19H30ClNO
|
1
|
| 1 |
Ki = 805 nM
|
|
|
|
CP0659152
|
7-isopropyl-4-(3-(methylamino)azetidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
Ki = 831.76 nM
|
|
|
|
CP0391412
|
7-(2-morpholin-4-ylethyl)-4-(4-morpholin-4-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C21H33N7O2
|
1
|
| 1 |
Ki = 848 nM
|
|
|
|
CP0659372
|
7-tert-butyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H23N5
|
1
|
| 1 |
Ki = 851.14 nM
|
|
|
|
CP0566445
|
5-methyl-2-phenyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C18H24N2OS
|
1
|
| 1 |
Ki = 870 nM
|
|
|
|
CP0862785
|
2-(4-(4-(4-(tert-butyl)phenoxy)butyl)piperazin-1-yl)pyrimidine
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 883 nM
|
|
|
|
CP0352542
|
1-[4-[4-(4-pyridin-3-ylpiperazin-1-yl)butoxy]phenyl]ethanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 908 nM
|
|
|
|
CP0487151
|
2-(4-chlorophenyl)-5-methyl-4-(3-piperidin-1-ylpropoxy)-1,3-thiazole
Show/Hide
|
C18H23ClN2OS
|
1
|
| 1 |
Ki = 930 nM
|
|
|
|
CP0673019
|
(R)-7-cyclopropyl-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C15H20N6
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0398759
|
(2R,4S)-N,N-dimethyl-4-(3-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0387512
|
6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C9H16N6
|
1
|
| 1 |
Ki = 1080 nM
|
|
|
|
CP0428880
|
(2S,4R)-4-(4-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0476820
|
5-methyl-4-(3-piperidin-1-ylpropoxy)-2-pyrazin-2-yl-1,3-thiazole
Show/Hide
|
C16H22N4OS
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0552644
|
N-(3,5-dimethoxyphenyl)-5-(2-piperidin-1-ylethyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C17H24N4O3
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0520235
|
3-benzoyl-1-(3-piperidin-1-ylpropyl)pyrimidine-2,4-dione
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
Ki = 1148.15 nM
|
|
|
|
CP0525395
|
2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C16H22N4O
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0352541
|
1-[4-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butoxy]phenyl]ethanone
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0477332
|
N-phenyl-5-(3-piperidin-1-ylpropyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C16H22N4O
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0554357
|
5-(2-piperidin-1-ylethyl)-N-[4-(trifluoromethoxy)phenyl]-1,3,4-oxadiazol-2-amine
Show/Hide
|
C16H19F3N4O2
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0396768
|
1-[4-[4-(4-pyridin-3-ylpiperazin-1-yl)butoxy]phenyl]propan-1-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 1392 nM
|
|
|
|
CP0426700
|
1-[4-[3-[4-(oxolan-2-yl)piperazin-1-yl]propoxy]phenyl]propan-1-one
Show/Hide
|
C20H30N2O3
|
1
|
| 1 |
Ki = 1392 nM
|
|
|
|
CP0562882
|
1-[4-[4-(4-pyridin-2-ylpiperazin-1-yl)butoxy]phenyl]propan-1-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 1444 nM
|
|
|
|
CP0043846
|
7-ethyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
Ki = 1513.56 nM
|
|
|
|
CP0366178
|
N-[2-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl]phenyl]acetamide
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
Ki = 1526 nM
|
|
|
|
CP0477333
|
N-(4-chlorophenyl)-5-(2-piperidin-1-ylethyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C15H19ClN4O
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0477334
|
N-(4-methoxyphenyl)-5-(2-piperidin-1-ylethyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C16H22N4O2
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0574692
|
diethyl 4-[3-ethoxy-4-(3-piperidin-1-ylpropoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C29H42N2O6
|
1
|
| 1 |
Ki = 1619 nM
|
|
|
|
CP0376706
|
(2S)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
Ki = 1621.81 nM
|
|
|
|
CP0396769
|
1-[4-[4-(4-pyrazin-2-ylpiperazin-1-yl)butoxy]phenyl]ethanone
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 1634 nM
|
|
|
|
CP0388382
|
2-(1,4'-bipiperidin-1'-yl)-5-chlorothiazolo[5,4-b]pyridine
Show/Hide
|
C16H21ClN4S
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0516955
|
1-[4-[3-(4-pyrazin-2-ylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 1720 nM
|
|
|
|
CP0435962
|
N-phenyl-5-(2-piperidin-1-ylethyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C15H20N4O
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0435968
|
5-methyl-2-pyrazin-2-yl-4-(2-pyrrolidin-1-ylethoxy)-1,3-thiazole
Show/Hide
|
C14H18N4OS
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0718475
|
2-(4-(4-(4-(tert-pentyl)phenoxy)butyl)piperazin-1-yl)pyrimidine
Show/Hide
|
C23H34N4O
|
1
|
| 1 |
Ki = 2264 nM
|
|
|
|
CP0532197
|
1-[4-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propoxy]phenyl]ethanone
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 2316 nM
|
|
|
|
CP0532791
|
1-[4-[3-(4-pyrazin-2-ylpiperazin-1-yl)propoxy]phenyl]ethanone
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 2453 nM
|
|
|
|
CP0398354
|
(2R,4R)-4-(2-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 2600 nM
|
|
|
|
CP0469140
|
1-[[1-[3-(1H-imidazol-5-yl)propyl]triazol-4-yl]methyl]-4-methylpiperazine
Show/Hide
|
C14H23N7
|
1
|
| 1 |
Ki = 2691.53 nM
|
|
|
|
CP0415883
|
4-[4-[1-[4-[1-[6-[(2-methylpropan-2-yl)oxycarbonylamino]hexyl]triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
Show/Hide
|
C46H54F3N5O4
|
1
|
| 1 |
Ki = 2770 nM
|
|
|
|
CP0842770
|
1-(4-(4-(tert-butyl)phenoxy)butyl)-4-(pyridin-2-yl)piperazine
Show/Hide
|
C23H33N3O
|
1
|
| 1 |
Ki = 2957 nM
|
|
|
|
CP0081459
|
7-(furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine
Show/Hide
|
C16H17N5O
|
2
|
| 1 |
Ki = 3388.44 nM
|
|
|
| 2 |
Ki = 3408 nM
|
|
|
|
CP0470593
|
1-[4-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 3390 nM
|
|
|
|
CP0842769
|
1-(4-(4-(tert-butyl)phenoxy)butyl)-4-(pyridin-3-yl)piperazine
Show/Hide
|
C23H33N3O
|
1
|
| 1 |
Ki = 3420 nM
|
|
|
|
CP0560738
|
1-[4-[4-(4-pyrazin-2-ylpiperazin-1-yl)butoxy]phenyl]propan-1-one
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Ki = 3627 nM
|
|
|
|
CP0924186
|
1-(3-(4-(tert-pentyl)phenoxy)propyl)-4-(pyridin-3-yl)piperazine
Show/Hide
|
C23H33N3O
|
1
|
| 1 |
Ki = 3654 nM
|
|
|
|
CP0396770
|
1-[4-[4-(4-pyridin-2-ylpiperazin-1-yl)butoxy]phenyl]ethanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 3697 nM
|
|
|
|
CP0718476
|
2-(4-(3-(4-(tert-butyl)phenoxy)propyl)piperazin-1-yl)pyrimidine
Show/Hide
|
C21H30N4O
|
1
|
| 1 |
Ki = 3827 nM
|
|
|
|
CP0525396
|
6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]oxazolo[4,5-b]pyridine
Show/Hide
|
C16H21BrN4O
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0561115
|
1-[4-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butoxy]phenyl]propan-1-one
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Ki = 4040 nM
|
|
|
|
CP0398382
|
(2R,4S)-N,N-dimethyl-4-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0552645
|
N,N-dimethyl-3-[(5-methyl-2-phenyl-1,3-thiazol-4-yl)oxy]propan-1-amine
Show/Hide
|
C15H20N2OS
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0428881
|
(2S,4S)-4-(2-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 4200 nM
|
|
|
|
CP0561116
|
1-[4-[3-[4-(oxolan-2-yl)piperazin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C19H28N2O3
|
1
|
| 1 |
Ki = 4889 nM
|
|
|
|
CP0041262
|
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 5011.87 nM
|
|
|
|
CP0398378
|
(2S,4R)-N,N-dimethyl-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 5100 nM
|
|
|
|
CP0960941
|
1-(3-(4-(tert-pentyl)phenoxy)propyl)-4-(pyridin-2-yl)piperazine
Show/Hide
|
C23H33N3O
|
1
|
| 1 |
Ki = 5196 nM
|
|
|
|
CP0949240
|
2-(4-(3-(4-(tert-pentyl)phenoxy)propyl)piperazin-1-yl)pyrimidine
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 5405 nM
|
|
|
|
CP0833058
|
2-(4-(4-(4-(tert-butyl)phenoxy)butyl)piperazin-1-yl)pyrazine
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 5477 nM
|
|
|
|
CP0435964
|
N-(4-chlorophenyl)-5-[3-(dimethylamino)propyl]-1,3,4-oxadiazol-2-amine
Show/Hide
|
C13H17ClN4O
|
1
|
| 1 |
Ki = 5700 nM
|
|
|
|
CP0566446
|
(5-methyl-2-phenyl-1,3-thiazol-4-yl) 4-methylpiperazine-1-carboxylate
Show/Hide
|
C16H19N3O2S
|
1
|
| 1 |
Ki = 5800 nM
|
|
|
|
CP0435967
|
N,N-dimethyl-3-[(5-methyl-2-pyrazin-2-yl-1,3-thiazol-4-yl)oxy]propan-1-amine
Show/Hide
|
C13H18N4OS
|
1
|
| 1 |
Ki = 5900 nM
|
|
|
|
CP0542870
|
6-(2-pyrrolidin-1-ylethoxy)-2,3-dihydroinden-1-one
Show/Hide
|
C15H19NO2
|
1
|
| 1 |
Ki = 6118 nM
|
|
|
|
CP0958098
|
2-(4-(3-(4-(tert-pentyl)phenoxy)propyl)piperazin-1-yl)pyrazine
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 6212 nM
|
|
|
|
CP0503458
|
4-(cyclohexylmethyl)-1-(3-imidazol-1-ylpropyl)triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 6309.57 nM
|
|
|
|
CP0397759
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1-(3-piperidin-1-ylpropyl)pyrimidine-2,4-dione
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C12H19N3O2
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1
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| 1 |
Ki = 7079.46 nM
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CP0930618
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1-(3-(4-(tert-butyl)phenoxy)propyl)-4-(pyridin-3-yl)piperazine
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C22H31N3O
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1
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| 1 |
Ki = 8156 nM
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CP0494462
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2-[4-[3-(4-tert-butylphenoxy)propyl]piperazin-1-yl]pyrazine
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C21H30N4O
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1
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| 1 |
Ki = 8740 nM
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CP0674429
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2-amino-4-(3-(methylamino)azetidin-1-yl)pyrido[3,2-d]pyrimidine-7-carbonitrile
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C12H13N7
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1
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| 1 |
Ki = 9549.93 nM
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CP0002070
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1-(1H-Indol-3-yl)-2-propanamine
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C11H14N2
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1
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| 1 |
Ki > 10000 nM
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CP0002071
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N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
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C17H22N2O
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1
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| 1 |
Ki > 10000 nM
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CP0635067
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2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
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C8H9Cl2N3
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1
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| 1 |
Ki > 10000 nM
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CP0398755
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(2R,4S)-N,N-dimethyl-4-(3-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
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C24H26ClN
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1
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| 1 |
Ki > 10000 nM
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CP0518738
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(2R,4S)-4-cyclooctyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
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C20H32ClN
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1
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| 1 |
Ki > 10000 nM
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CP0862784
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(4-(3-(4-(tert-butyl)phenoxy)propyl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
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C21H34N2O2
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1
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| 1 |
Ki > 10000 nM
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CP0915464
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(4-(4-(4-(tert-pentyl)phenoxy)butyl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
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C23H38N2O2
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1
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| 1 |
Ki > 10000 nM
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CP0930619
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(4-(3-(4-(tert-pentyl)phenoxy)propyl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
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C22H36N2O2
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1
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| 1 |
Ki > 10000 nM
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CP0943915
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1-(3-(4-(tert-Butyl)phenoxy)propyl)-4-(pyridin-2-yl)piperazine
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C22H31N3O
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1
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| 1 |
Ki > 10000 nM
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CP0949327
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1-(4-(4-(tert-pentyl)phenoxy)butyl)-4-(pyridin-3-yl)piperazine
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C24H35N3O
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1
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| 1 |
Ki > 10000 nM
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CP0952106
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(4-(4-(4-(tert-butyl)phenoxy)butyl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
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C22H36N2O2
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1
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| 1 |
Ki > 10000 nM
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CP0482947
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(5-methyl-2-pyrazin-2-yl-1,3-thiazol-4-yl) 4-methylpiperazine-1-carboxylate
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C14H17N5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0560740
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1-[4-[4-[4-(oxolan-2-yl)piperazin-1-yl]butoxy]phenyl]ethanone
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C20H30N2O3
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1
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| 1 |
Ki > 10000 nM
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CP0562881
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1-[4-[4-[4-(oxolan-2-yl)piperazin-1-yl]butoxy]phenyl]propan-1-one
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C21H32N2O3
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1
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| 1 |
Ki > 10000 nM
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CP0209146
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4-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C14H17ClN6
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1
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| 1 |
Ki = 13200 nM
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CP0319491
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4-(4-bromophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C14H17BrN6
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1
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| 1 |
Ki = 15000 nM
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CP0884652
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4-(3-(4-(cyclohexylmethyl)-1H-1,2,3-triazol-1-yl)propyl)morpholine fumarate salt
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C20H32N4O5
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1
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| 1 |
Ki = 18620.87 nM
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CP0482188
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6-(4-fluorophenyl)-4-piperazin-1-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
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C16H17FN6
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1
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| 1 |
Ki = 84660 nM
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CP0521795
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3-[2-[(2S)-2-methylpyrrolidin-1-yl]ethyl]pyridine
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C12H18N2
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1
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| 1 |
Ki > 330 nM
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CP0414030
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US8796297, 4
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C7H13N5
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1
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| 1 |
Ki > 331 nM
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CP0470059
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US8796297, 11
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C9H17N5
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1
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| 1 |
Ki > 339 nM
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CP0475529
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US8796297, 5
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C8H15N5
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1
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| 1 |
Ki > 339 nM
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CP0510856
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3-(2-pyrrolidin-1-ylethyl)pyridine
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C11H16N2
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1
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| 1 |
Ki > 340 nM
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CP0050247
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2-(2-pyrrolidin-1-ylethyl)pyridine
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C11H16N2
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1
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| 1 |
Ki > 350 nM
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CP0413795
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US8796297, 15
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C15H25N5O2
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1
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| 1 |
Ki > 355 nM
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CP0502025
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N,N-dimethyl-4-(2-pyrrolidin-1-ylethyl)aniline
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C14H22N2
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1
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| 1 |
Ki > 360 nM
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CP0535859
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1-(2-thiophen-2-ylethyl)pyrrolidine
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C10H15NS
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1
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| 1 |
Ki > 360 nM
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CP0411040
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US8796297, 16
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C10H17N5
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1
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| 1 |
Ki > 363 nM
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CP0441410
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US8796297, 18
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C8H13N5
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1
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| 1 |
Ki > 363 nM
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CP0549770
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US8796297, 17
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C13H21N5O2
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1
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| 1 |
Ki > 363 nM
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CP0458991
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US8796297, 14
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C13H21N5O2
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1
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| 1 |
Ki > 380 nM
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CP0025667
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2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
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C18H19ClN4
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1
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| 1 |
Ki > 1000 nM
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CP0033479
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(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
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C17H19ClN2S
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1
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| 1 |
Ki > 1000 nM
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CP0047409
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2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride
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C22H26F3N3OS
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1
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| 1 |
Ki > 1000 nM
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CP0058675
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N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
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C20H23N
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1
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| 1 |
Ki > 1000 nM
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CP0060491
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10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
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C20H23N
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1
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| 1 |
Ki > 1000 nM
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CP0134204
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(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
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C18H18ClNS
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1
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| 1 |
Ki > 1000 nM
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CP0439299
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4-(3-(4,4-difluoropiperidin-1-yl)propoxy)benzonitrile
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C15H18F2N2O
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1
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| 1 |
Ki > 1000 nM
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CP0388207
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1-(4-methyl-2-(3-(piperidin-1-yl)propylthio)thiazol-5-yl)ethanone
Show/Hide
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C14H22N2OS2
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1
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| 1 |
Ki > 1000 nM
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CP0435961
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5-[3-(dimethylamino)propyl]-N-phenyl-1,3,4-oxadiazol-2-amine
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C13H18N4O
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1
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| 1 |
Ki > 5000 nM
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CP0487147
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N-[3-(diethylamino)propyl]-3-(4-methoxyphenyl)-1,2,4-oxadiazole-5-carboxamide
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C17H24N4O3
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1
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| 1 |
Ki > 5000 nM
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CP0513318
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N-(3,5-dimethoxyphenyl)-5-[(dimethylamino)methyl]-1,3,4-oxadiazol-2-amine
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C13H18N4O3
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1
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| 1 |
Ki > 5000 nM
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CP0513319
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N-[3-(diethylamino)propyl]-3-phenyl-1,2,4-oxadiazole-5-carboxamide
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C16H22N4O2
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1
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| 1 |
Ki > 5000 nM
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CP0559556
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N-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1,3,4-oxadiazol-2-amine
Show/Hide
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C14H17ClN4O
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1
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| 1 |
Ki > 5000 nM
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CP0560744
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5-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
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C12H16N4O2
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1
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| 1 |
Ki > 5000 nM
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CP0563117
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5-(1-methylpiperidin-4-yl)-N-phenyl-1,3,4-oxadiazol-2-amine
Show/Hide
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C14H18N4O
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1
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| 1 |
Ki > 5000 nM
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CP0563118
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N-(4-methoxyphenyl)-5-(1-methylpiperidin-4-yl)-1,3,4-oxadiazol-2-amine
Show/Hide
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C15H20N4O2
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1
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| 1 |
Ki > 5000 nM
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CP0566444
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3-phenyl-N-(3-piperidin-1-ylpropyl)-1,2,4-oxadiazole-5-carboxamide
Show/Hide
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C17H22N4O2
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1
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| 1 |
Ki > 5000 nM
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