Brief Information of the Compound and Protein
Compound Name
2-(4-(4-(4-(tert-butyl)phenoxy)butyl)piperazin-1-yl)pyrazine
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PubChem ID
CID: 145958342
Canonical SMILES
CC(C)(C)c1ccc(OCCCCN2CCN(c3cnccn3)CC2)cc1
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Compound Formula C22H32N4O
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 5477 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5477 nM