General Information of the Compound
| Compound ID |
CP0398378
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| Compound Name |
(2S,4R)-N,N-dimethyl-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
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| Structure |
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| Formula |
C19H21ClF3N
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| Molecular Weight |
355.831
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| Canonical SMILES |
Cl.CN(C)[C@H]1C[C@H](c2ccc(cc2)C(F)(F)F)c2ccccc2C1
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| InChI |
InChI=1S/C19H20F3N.ClH/c1-23(2)16-11-14-5-3-4-6-17(14)18(12-16)13-7-9-15(10-8-13)19(20,21)22;/h3-10,16,18H,11-12H2,1-2H3;1H/t16-,18-;/m1./s1
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| InChIKey |
HWFFVVLUGHDJCD-PHJLCXHGSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01019, 5-hydroxytryptamine receptor 2B
Protein ID: PT00939, 5-hydroxytryptamine receptor 2C
Protein ID: PT01194, Histamine H3 receptor