Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-propan-2-yl-1,4-diazepan-1-yl)-[1-[6-(trifluoromethyl)pyridin-3-yl]piperidin-4-yl]methanone
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 PubChem ID
CID: 11452311
SID: 16551353
Canonical SMILES
CC(C)N1CCCN(CC1)C(=O)C1CCN(CC1)c1ccc(nc1)C(F)(F)F
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Compound Formula C20H29F3N4O
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.1259 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.512 nM
2 Ki = 0.3162 nM