| Compound ID |
Compound Name |
Compound Formula |
|
CP0386020
|
1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
EC50 = 0.03162 nM
|
|
|
|
CP0024732
|
5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide
Show/Hide
|
C26H27N5O2
|
4
|
| 1 |
EC50 = 0.12 nM
|
|
|
| 2 |
EC50 = 0.79 nM
|
|
|
| 3 |
Ki = 0.2 nM
|
|
|
| 4 |
Ki = 28 nM
|
|
|
|
CP0086279
|
methyl 3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-1-yl)piperazin-1-yl]butyl]-1H-indole-5-carboxylate
Show/Hide
|
C31H37N5O2
|
1
|
| 1 |
EC50 < 0.14 nM
|
|
|
|
CP0246515
|
8-[4-[4-(5-methoxy-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C30H37N5O
|
1
|
| 1 |
EC50 < 0.14 nM
|
|
|
|
CP0516898
|
8-[4-[4-(5-bromo-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C29H34BrN5
|
1
|
| 1 |
EC50 = 0.35 nM
|
|
|
|
CP0114508
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-1-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H34N6
|
1
|
| 1 |
EC50 = 0.36 nM
|
|
|
|
CP0261286
|
3-[4-[4-(9-amino-2,3-dihydro-1H-cyclopenta[b]quinolin-8-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C29H32N6
|
1
|
| 1 |
EC50 = 0.58 nM
|
|
|
|
CP0236109
|
8-[4-[4-(5-methyl-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C30H37N5
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0564524
|
8-[4-[4-(5-fluoro-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C29H34FN5
|
1
|
| 1 |
EC50 = 0.72 nM
|
|
|
|
CP0241040
|
8-[4-[4-(5-chloro-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C29H34ClN5
|
1
|
| 1 |
EC50 = 0.75 nM
|
|
|
|
CP0512804
|
8-[4-[4-(1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C29H35N5
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0466386
|
7-[butyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
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|
C17H27NO
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0369904
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-4-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H34N6
|
1
|
| 1 |
EC50 = 1.55 nM
|
|
|
|
CP0170130
|
(6aR,9R)-N-[(2R,5S,8S,8aS)-8-benzyl-8a-hydroxy-2-methyl-5-(2-methylpropyl)-3,6-dioxo-7,8-dihydro-5H-[1,3]oxazolo[3,2-a]pyrazin-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Show/Hide
|
C34H39N5O5
|
2
|
| 1 |
EC50 = 1.995 nM
|
|
|
| 2 |
Ki = 0.0631 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C16H25NO
|
8
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
EC50 = 6 nM
|
|
|
| 3 |
IC50 = 0.53 nM
|
|
|
| 4 |
IC50 = 6 nM
|
|
|
| 5 |
Ki = 0.4 nM
|
|
|
| 6 |
Ki = 0.75 nM
|
|
|
| 7 |
Ki = 2.1 nM
|
|
|
| 8 |
Ki = 5.1 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
Show/Hide
|
C10H12N2O
|
8
|
| 1 |
EC50 = 3.75 nM
|
|
|
| 2 |
EC50 = 8.71 nM
|
|
|
| 3 |
EC50 = 19 nM
|
|
|
| 4 |
Ki = 0.62 nM
|
|
|
| 5 |
Ki = 0.9 nM
|
|
|
| 6 |
Ki = 1.2 nM
|
|
|
| 7 |
Ki = 3.981 nM
|
|
|
| 8 |
Ki < 50 nM
|
|
|
|
CP0532000
|
N-cyclohexyl-2-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]-N-phenylacetamide
Show/Hide
|
C29H37FN4O
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0572042
|
3-[4-[4-[4-[3-(1-prop-2-enylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C34H43N5O
|
1
|
| 1 |
EC50 = 8.6 nM
|
|
|
|
CP0577453
|
3-[4-[4-[4-[3-(1-ethylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C33H43N5O
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0567601
|
3-[4-[4-[4-[3-[1-(cyclopropylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C35H45N5O
|
1
|
| 1 |
EC50 = 9.1 nM
|
|
|
|
CP0369905
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-2-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H34N6
|
1
|
| 1 |
EC50 = 14.93 nM
|
|
|
|
CP0569866
|
3-[4-[4-[4-[3-[1-[(3-methylphenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C39H47N5O
|
1
|
| 1 |
EC50 = 17.92 nM
|
|
|
|
CP0573136
|
3-[4-[4-[4-[3-[1-(furan-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C36H43N5O2
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0077913
|
5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C29H28ClN5O
|
1
|
| 1 |
EC50 = 19.05 nM
|
|
|
|
CP0576308
|
3-[4-[4-[4-[3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C37H44N6O
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0575679
|
3-[4-[4-[4-[3-[1-(1H-pyrrol-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C36H44N6O
|
1
|
| 1 |
EC50 = 22.2 nM
|
|
|
|
CP0542636
|
methyl 3-[4-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carboxylate
Show/Hide
|
C39H48N4O3
|
1
|
| 1 |
EC50 = 22.4 nM
|
|
|
|
CP0483492
|
N-propan-2-yl-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C22H30N4O
|
1
|
| 1 |
EC50 = 22.8 nM
|
|
|
|
CP0528554
|
N-(cyclopropylmethyl)-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
EC50 = 24.9 nM
|
|
|
|
CP0579382
|
3-[4-[4-[4-[3-(1-butylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C35H47N5O
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0569868
|
3-[3-[4-[4-[3-[1-(1H-pyrrol-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C35H42N6O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0576776
|
3-[3-[4-[4-[3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C36H42N6O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0498404
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5-methoxy-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
|
C38H48N4O2
|
1
|
| 1 |
EC50 = 28.3 nM
|
|
|
|
CP0386754
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-3-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H34N6
|
1
|
| 1 |
EC50 = 28.8 nM
|
|
|
|
CP0567306
|
3-[4-[4-[4-[3-(1-prop-2-ynylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C34H41N5O
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0578725
|
3-[3-[4-[4-[3-[1-(furan-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C35H41N5O2
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0576304
|
3-[4-[4-[4-[3-[1-(cyclobutylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C36H47N5O
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0530863
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-4-yl)piperazin-1-yl]butanoyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H32N6O
|
1
|
| 1 |
EC50 = 34.98 nM
|
|
|
|
CP0966610
|
3-(4-(4-(2-((1-Benzylpiperidin-4-yl)methyl)-3-oxo-2,3-dihydro-1H-inden-4-yl)piperazin-1-yl)butyl)-1H-indole-5-carbonitrile
Show/Hide
|
C39H45N5O
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0424880
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propan-2-ylbenzamide
Show/Hide
|
C23H29Cl2N3O
|
1
|
| 1 |
EC50 = 46.1 nM
|
|
|
|
CP0576305
|
3-[4-[4-[4-[3-[1-(cyclopentylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C37H49N5O
|
1
|
| 1 |
EC50 = 49.82 nM
|
|
|
|
CP0561909
|
3-[3-[4-(9-amino-5,6,7,8-tetrahydroacridin-1-yl)piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C29H32N6
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0483491
|
N-propyl-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C22H30N4O
|
1
|
| 1 |
EC50 = 54.5 nM
|
|
|
|
CP0317610
|
1,1-dioxo-2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
2
|
| 1 |
EC50 = 56 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0916862
|
3-(4-(4-(2-((1-Benzylpiperidin-4-yl)methyl)-3-oxo-2,3-dihydro-1H-inden-5-yl)piperazin-1-yl)butyl)-1H-indole-5-carbonitrile
Show/Hide
|
C39H45N5O
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0498403
|
3-[4-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H45N5O
|
1
|
| 1 |
EC50 = 58.6 nM
|
|
|
|
CP0364518
|
3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-1-yl)piperazin-1-yl]butanoyl]-1H-indole-5-carbonitrile
Show/Hide
|
C30H32N6O
|
1
|
| 1 |
EC50 = 62.43 nM
|
|
|
|
CP0542638
|
3-[4-[4-[4-[3-[1-(cyclohexylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H51N5O
|
1
|
| 1 |
EC50 = 65.24 nM
|
|
|
|
CP0542639
|
3-[3-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C37H43N5O
|
1
|
| 1 |
EC50 = 65.53 nM
|
|
|
|
CP0573137
|
3-[4-[4-[4-[3-[1-(thiophen-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C36H43N5OS
|
1
|
| 1 |
EC50 = 66.6 nM
|
|
|
|
CP0327581
|
N-[8-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1,2,3,4-tetrahydroacridin-9-yl]acetamide
Show/Hide
|
C32H36N6O
|
1
|
| 1 |
EC50 = 93.37 nM
|
|
|
|
CP0576306
|
3-[4-[4-[4-[3-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H44FN5O
|
1
|
| 1 |
EC50 = 99.61 nM
|
|
|
|
CP0575795
|
3-[4-[4-[4-[3-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H44FN5O
|
1
|
| 1 |
EC50 = 106.6 nM
|
|
|
|
CP0575682
|
3-[4-[4-[3-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H45N5O
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0577897
|
3-[4-[4-[4-[3-[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C39H47N5O2
|
1
|
| 1 |
EC50 = 123.78 nM
|
|
|
|
CP0401481
|
4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine
Show/Hide
|
C17H17F2NO
|
1
|
| 1 |
EC50 = 137 nM
|
|
|
|
CP0386755
|
3-[4-[4-(11-amino-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-1-yl)piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C31H36N6
|
1
|
| 1 |
EC50 = 146.01 nM
|
|
|
|
CP0576309
|
3-[3-[4-[4-[3-[1-(thiophen-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]propyl]-1H-indole-5-carbonitrile
Show/Hide
|
C35H41N5OS
|
1
|
| 1 |
EC50 = 160.5 nM
|
|
|
|
CP0574888
|
3-[4-[4-[4-[3-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H44FN5O
|
1
|
| 1 |
EC50 = 161.74 nM
|
|
|
|
CP0577452
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5-bromo-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
|
C37H45BrN4O
|
1
|
| 1 |
EC50 = 169 nM
|
|
|
|
CP0552800
|
N-(cyclopropylmethyl)-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
|
C24H29Cl2N3O
|
1
|
| 1 |
EC50 = 175.1 nM
|
|
|
|
CP0574889
|
3-[4-[4-[4-[3-[1-[(3-bromophenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H44BrN5O
|
1
|
| 1 |
EC50 = 175.6 nM
|
|
|
|
CP0570984
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5-fluoro-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
|
C37H45FN4O
|
1
|
| 1 |
EC50 = 184 nM
|
|
|
|
CP0169939
|
(-)-Corydalmine
Show/Hide
|
C20H23NO4
|
2
|
| 1 |
EC50 = 190 nM
|
|
|
| 2 |
Ki = 149 nM
|
|
|
|
CP0498398
|
3-[4-[4-[4-[3-[1-[(3-chlorophenyl)methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C38H44ClN5O
|
1
|
| 1 |
EC50 = 202.54 nM
|
|
|
|
CP0576303
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5-chloro-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
|
C37H45ClN4O
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0401448
|
4-(2-(3-fluorophenoxy)phenyl)piperidine
Show/Hide
|
C17H18FNO
|
1
|
| 1 |
EC50 = 219 nM
|
|
|
|
CP0567569
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5-methyl-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
|
C38H48N4O
|
1
|
| 1 |
EC50 = 278.8 nM
|
|
|
|
CP0967935
|
3-(3-(4-(2-((1-Benzylpiperidin-4-yl)methyl)-1-oxo-2,3-dihydro-1H-inden-5-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile
Show/Hide
|
C38H45N5O
|
1
|
| 1 |
EC50 = 316 nM
|
|
|
|
CP0498399
|
3-[4-[4-[4-[3-[1-[[3-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
|
C39H44F3N5O
|
1
|
| 1 |
EC50 = 323.46 nM
|
|
|
|
CP0568984
|
3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
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C37H46N4O
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1
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| 1 |
EC50 = 334 nM
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CP0424885
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N-(oxetan-3-yl)-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
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C22H28N4O2
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1
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| 1 |
EC50 = 373.8 nM
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CP0577451
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3-[4-[4-[2-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
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C38H45N5O
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1
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| 1 |
EC50 = 405 nM
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CP0532001
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propylbenzamide
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C23H29Cl2N3O
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1
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| 1 |
EC50 = 451.6 nM
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CP0574890
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3-[2-[4-[4-[3-[1-(furan-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C34H39N5O2
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1
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| 1 |
EC50 = 467 nM
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CP0969997
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(1-Benzylpiperidin-4-yl)methyl)-1-oxo-2,3-dihydro-1H-inden-5-yl)piperazin-1-yl)butyl)-1H-indole-5-carbonitrle
Show/Hide
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C39H45N5O
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1
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| 1 |
EC50 = 521 nM
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CP0498400
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3-[2-[4-[4-[3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C35H40N6O
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1
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| 1 |
EC50 = 547 nM
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CP0072679
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3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-3-yl)piperazin-1-yl]butanoyl]-1H-indole-5-carbonitrile
Show/Hide
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C30H32N6O
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1
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| 1 |
EC50 = 567 nM
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CP0424883
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
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C23H27Cl2N3O2
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1
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| 1 |
EC50 = 583.2 nM
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CP0498405
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3-[2-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C36H41N5O
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1
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| 1 |
EC50 = 619.88 nM
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CP0542635
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3-[4-[4-[(2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-1-oxo-3H-inden-5-yl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
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C39H43N5O
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1
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| 1 |
EC50 = 653 nM
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CP0438753
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4-(3-fluoro-2-phenoxyphenyl)piperidine
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C17H18FNO
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1
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| 1 |
EC50 = 877 nM
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CP0430772
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4-(2-(3-chlorophenoxy)phenyl)piperidine
Show/Hide
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C17H18ClNO
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1
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| 1 |
EC50 = 1150 nM
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CP0123293
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3-[4-[4-(9-amino-5,6,7,8-tetrahydroacridin-2-yl)piperazin-1-yl]butanoyl]-1H-indole-5-carbonitrile
Show/Hide
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C30H32N6O
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1
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| 1 |
EC50 = 1563.21 nM
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CP0373835
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1-(2-(benzyloxy)phenyl)piperazine
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C17H20N2O
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1
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| 1 |
EC50 > 10000 nM
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CP0261287
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3-[2-[4-(9-amino-5,6,7,8-tetrahydroacridin-1-yl)piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C28H30N6
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1
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| 1 |
EC50 > 10000 nM
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CP0044469
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(1S)-16-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-17-ol
Show/Hide
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C19H19NO4
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2
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| 1 |
EC50 = 13500 nM
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| 2 |
Ki = 908 nM
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CP0515605
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1-(3-chlorophenyl)sulfonyl-2-ethyl-4-piperazin-1-ylimidazo[4,5-c]pyridine
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C18H20ClN5O2S
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1
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| 1 |
EC50 > 20000 nM
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CP0498401
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3-[[4-[4-[3-[1-(thiophen-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]methyl]-1H-indole-5-carbonitrile
Show/Hide
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C33H37N5OS
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1
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| 1 |
EC50 > 1000 nM
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CP0498402
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3-[2-[4-[4-[3-[1-(thiophen-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C34H39N5OS
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1
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| 1 |
EC50 > 1000 nM
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CP0542640
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3-[[4-[4-[3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]methyl]-1H-indole-5-carbonitrile
Show/Hide
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C34H38N6O
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1
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| 1 |
EC50 > 1000 nM
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CP0542641
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3-[2-[4-[4-[3-[1-(1H-pyrrol-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]ethyl]-1H-indole-5-carbonitrile
Show/Hide
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C34H40N6O
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1
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| 1 |
EC50 > 1000 nM
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CP0569867
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3-[[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]methyl]-1H-indole-5-carbonitrile
Show/Hide
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C35H39N5O
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1
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| 1 |
EC50 > 1000 nM
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CP0575681
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3-[[4-[4-[3-[1-(furan-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]methyl]-1H-indole-5-carbonitrile
Show/Hide
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C33H37N5O2
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1
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| 1 |
EC50 > 1000 nM
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CP0576307
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3-[4-[4-[4-[3-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
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C42H47N5O
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1
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| 1 |
EC50 > 1000 nM
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CP0576385
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3-[[4-[4-[3-[1-(1H-pyrrol-3-ylmethyl)piperidin-4-yl]propanoyl]phenyl]piperazin-1-yl]methyl]-1H-indole-5-carbonitrile
Show/Hide
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C33H38N6O
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1
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| 1 |
EC50 > 1000 nM
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CP0577896
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3-(1-benzylpiperidin-4-yl)-1-[4-[4-[4-(5,6-dichloro-1H-indol-3-yl)butyl]piperazin-1-yl]phenyl]propan-1-one
Show/Hide
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C37H44Cl2N4O
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1
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| 1 |
EC50 > 1000 nM
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CP0578724
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3-[4-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-6-carbonitrile
Show/Hide
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C38H45N5O
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1
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| 1 |
EC50 > 1000 nM
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CP0950361
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3-((4-(2-((1-Benzylpiperidin-4-yl)methyl)-1-oxo-2,3-dihydro-1H-inden-5-yl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile
Show/Hide
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C36H39N5O
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1
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| 1 |
EC50 > 1000 nM
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CP0965915
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3-(2-(4-(2-((1-Benzylpiperidin-4-yl)methyl)-1-oxo-2,3-dihydro-1H-inden-5-yl)piperazin-1-yl)ethyl)-1H-indole-5-carbonitrile
Show/Hide
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C37H41N5O
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1
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| 1 |
EC50 > 1000 nM
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CP0795225
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1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
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C19H16N2O2S
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1
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| 1 |
IC50 = 1 nM
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CP0037866
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CAS_146714-97-8
Show/Hide
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C25H34N4O2
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2
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| 1 |
IC50 = 11.3 nM
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| 2 |
Ki = 2.2 nM
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CP0476547
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5-bromo-3-[3-[4-[3-(1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C26H31BrN4
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1
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| 1 |
IC50 = 15 nM
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CP0476546
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5-fluoro-3-[3-[4-[3-(1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C26H31FN4
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1
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| 1 |
IC50 = 16 nM
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CP0545110
|
US9359372, DC037032
Show/Hide
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C21H23NO4
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2
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| 1 |
IC50 = 51.53 nM
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| 2 |
Ki = 40.59 nM
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CP0429931
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3-[3-[4-[3-(5-bromo-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-5-methoxy-1H-indole
Show/Hide
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C27H33BrN4O
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1
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| 1 |
IC50 = 128 nM
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CP0724162
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2-Benzyl-N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
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C21H23ClN4
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1
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| 1 |
IC50 = 394.8 nM
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CP0218398
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6-[5-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]pentanoyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
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C28H30FN3O3
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1
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| 1 |
IC50 = 587.8 nM
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CP0484502
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5-methoxy-3-[3-[4-[3-(5-methoxy-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C28H36N4O2
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1
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| 1 |
IC50 = 599 nM
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CP0272711
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US9359372, DC037030
Show/Hide
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C20H23NO4
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2
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| 1 |
IC50 = 626.4 nM
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| 2 |
Ki = 493.48 nM
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CP0411958
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US9359372, DC037013
Show/Hide
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C20H21NO4
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2
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| 1 |
IC50 = 631.4 nM
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| 2 |
Ki = 497.43 nM
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CP0416777
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[(1S)-16,18-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-19-yl]methanol
Show/Hide
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C21H23NO5
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2
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| 1 |
IC50 = 758.03 nM
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| 2 |
Ki = 599.89 nM
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CP0673446
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2-Benzyl-N-(3-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
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C22H25ClN4O
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1
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| 1 |
IC50 = 822.8 nM
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CP0437785
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(13aS)-2,3,9,11-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Show/Hide
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C21H25NO4
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2
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| 1 |
IC50 = 922.44 nM
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| 2 |
Ki = 730.02 nM
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CP0674236
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2-Benzyl-N-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
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C21H22Cl2N4
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1
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| 1 |
IC50 = 1057 nM
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CP0484501
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5-bromo-3-[3-[4-[3-(5-bromo-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C26H30Br2N4
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1
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| 1 |
IC50 = 1200 nM
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CP0673445
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2-Benzyl-N-(3-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
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C21H22ClFN4
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1
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| 1 |
IC50 = 1252 nM
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CP0569708
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3-[3-[4-[3-(1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C26H32N4
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1
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| 1 |
IC50 = 2700 nM
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CP0484500
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3-[3-[4-[3-(1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-5-methoxy-1H-indole
Show/Hide
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C27H34N4O
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1
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| 1 |
IC50 = 4500 nM
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CP0523120
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3-[3-[4-[3-(5-bromo-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-5-fluoro-1H-indole
Show/Hide
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C26H30BrFN4
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1
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| 1 |
IC50 = 4900 nM
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CP0386073
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5-fluoro-3-[3-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C26H30F2N4
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1
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| 1 |
IC50 = 5700 nM
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CP0386072
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3-[3-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]propyl]-5-methoxy-1H-indole
Show/Hide
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C27H33FN4O
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1
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| 1 |
IC50 = 7200 nM
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CP0068074
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carboxamide
Show/Hide
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C27H28N6O2
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2
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| 1 |
Kd = 0.2042 nM
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| 2 |
Ki = 0.3162 nM
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CP0560060
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N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]quinolin-2-amine
Show/Hide
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C25H32N4O
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1
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| 1 |
Ki = 0.03 nM
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CP0218850
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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1
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| 1 |
Ki = 0.0631 nM
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CP0579231
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(3-chloro-4-fluorophenyl)-[4-[[3-(5-fluoro-1H-indol-3-yl)propylamino]methyl]piperidin-1-yl]methanone
Show/Hide
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C24H26ClF2N3O
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1
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| 1 |
Ki = 0.069 nM
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CP0068072
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3-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,3]triazolo[1,5-d][1,4]oxazine
Show/Hide
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C26H28N6O
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1
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| 1 |
Ki = 0.07943 nM
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CP0126585
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4-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 0.07943 nM
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CP0126586
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1-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]oxazine
Show/Hide
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C26H28N6O
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1
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| 1 |
Ki = 0.07943 nM
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CP0570555
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(3,4-dichlorophenyl)-[4-[[3-(5-fluoro-1H-indol-3-yl)propylamino]methyl]piperidin-1-yl]methanone
Show/Hide
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C24H26Cl2FN3O
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1
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| 1 |
Ki = 0.097 nM
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CP0064904
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,2-d][1,4]oxazine
Show/Hide
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C26H27N5O
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1
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| 1 |
Ki = 0.1259 nM
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CP0089790
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(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(pyrrolidin-1-yl)methanone
Show/Hide
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C31H34N6O2
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1
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| 1 |
Ki = 0.1259 nM
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CP0104145
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N-cyclopropyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C30H32N6O2
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1
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| 1 |
Ki = 0.1259 nM
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CP0216068
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N-(cyclopropylmethyl)-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C31H34N6O2
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1
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| 1 |
Ki = 0.1259 nM
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CP0068073
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N,N-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C29H32N6O2
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1
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| 1 |
Ki = 0.1585 nM
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CP0096954
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N-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C28H30N6O2
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1
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| 1 |
Ki = 0.1585 nM
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CP0226445
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azetidin-1-yl-[6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazin-3-yl]methanone
Show/Hide
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C30H32N6O2
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1
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| 1 |
Ki = 0.1585 nM
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CP0233604
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-2-(trifluoromethyl)-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
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C27H26F3N5O
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1
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| 1 |
Ki = 0.1585 nM
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CP0260884
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N-cyclobutyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C31H34N6O2
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1
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| 1 |
Ki = 0.1585 nM
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CP0270386
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4-methyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 0.1585 nM
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CP0036194
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1,2-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C28H31N5O
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1
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| 1 |
Ki = 0.1995 nM
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CP0036547
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine
Show/Hide
|
C26H27N5O
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1
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| 1 |
Ki = 0.1995 nM
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CP0069977
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2-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C27H29N5O
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1
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| 1 |
Ki = 0.1995 nM
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CP0097108
|
6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-N-propan-2-yl-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C30H34N6O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0440559
|
7-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinolin-2-amine
Show/Hide
|
C24H30N4O2
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0471417
|
6-methoxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quinolin-2-amine
Show/Hide
|
C25H32N4O2
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0420077
|
ethyl N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]carbamate
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0420806
|
(5Z)-3-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-[(3,4-dimethoxyphenyl)methylidene]imidazolidine-2,4-dione
Show/Hide
|
C26H30Cl2N4O4
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0530059
|
5-fluoro-3-[1-[2-(4-fluoro-2-phenylphenoxy)ethyl]piperidin-4-yl]-1H-indole
Show/Hide
|
C27H26F2N2O
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0283739
|
8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0332161
|
N-cyclopentyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C32H36N6O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0096953
|
1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone
Show/Hide
|
C28H29N5O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0099712
|
3-(2-aminoethyl)-1H-indole-5-carboxamide
Show/Hide
|
C11H13N3O
|
2
|
| 1 |
Ki = 0.34 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0405045
|
2-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2,6-diamine
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
Ki = 0.38 nM
|
|
|
|
CP0068076
|
(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(piperidin-1-yl)methanone
Show/Hide
|
C32H36N6O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0096951
|
(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(morpholino)methanone
Show/Hide
|
C31H34N6O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0406079
|
5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0502082
|
6-fluoro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H27FN4O
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0506561
|
5-(Dimethylamino)-2-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]-1H-isoindole-1,3(2H)-dione
Show/Hide
|
C24H30N4O3
|
1
|
| 1 |
Ki = 0.47 nM
|
|
|
|
CP0528277
|
7-methoxy-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]quinolin-2-amine
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0538117
|
5-(Dimethylamino)-2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-1H-isoindole-1,3(2H)-dione
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0041018
|
6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]tetrazolo[1,5-d][1,4]oxazine
Show/Hide
|
C24H25N7O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0407446
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C24H31N5OS
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0405600
|
5-fluoro-3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethyl]-1H-indole
Show/Hide
|
C26H26FN3
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0471416
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-6-methylquinolin-2-amine
Show/Hide
|
C25H32N4O
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0388497
|
ethyl N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]carbamate
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
Ki = 0.57 nM
|
|
|
|
CP0042265
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
Show/Hide
|
C23H27N3O3
|
2
|
| 1 |
Ki = 0.6 nM
|
|
|
| 2 |
Ki = 4.49 nM
|
|
|
|
CP0553478
|
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0124306
|
ethyl 6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxylate
Show/Hide
|
C29H31N5O3
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0406077
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0406080
|
1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0479139
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0502083
|
5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
|
C25H26N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0438702
|
6-Amino-2-[5-[4-(2-methoxyphenyl)-1-piperazinyl]pentyl]-1Hbenz[de]isoquinoline-1,3(2H)-dione
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
Ki = 0.67 nM
|
|
|
|
CP0432150
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]acetamide
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 0.69 nM
|
|
|
|
CP0402936
|
[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]piperidin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
Ki = 0.72 nM
|
|
|
|
CP0504542
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0258551
|
1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-methyl-5,5-diphenylimidazolidine-2,4-dione
Show/Hide
|
C31H36N4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0451765
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]cyclopropanecarboxamide
Show/Hide
|
C23H32N4OS
|
1
|
| 1 |
Ki = 0.92 nM
|
|
|
|
CP0170167
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-methylbenzenesulfonamide
Show/Hide
|
C22H31N3O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0233605
|
6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carbonitrile
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0406075
|
5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0406078
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0454396
|
5-[2-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0399644
|
(3S)-2-[6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C27H36N4O2S
|
3
|
| 1 |
Ki < 1 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
| 3 |
Ki = 98 nM
|
|
|
|
CP0400693
|
1-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]-7-[4-(2-propan-2-ylphenyl)piperazin-1-yl]heptan-1-one
Show/Hide
|
C30H48N4O2
|
3
|
| 1 |
Ki = 1 nM
|
|
|
| 2 |
Ki = 30 nM
|
|
|
| 3 |
Ki = 100 nM
|
|
|
|
CP0429607
|
1-[(2,4,6-trimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride (4)
Show/Hide
|
C23H32N2O2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0420807
|
(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazolidine-2,4-dione
Show/Hide
|
C31H40N4O5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0540392
|
2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C21H23Cl2N3O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0548332
|
2-[6-(4-phenylpiperazin-1-yl)hexyl]isoindole-1,3-dione
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0569767
|
2-[6-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0491320
|
2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxohexyl]isoindoline
Show/Hide
|
C25H33N3OS
|
1
|
| 1 |
Ki = 1.07 nM
|
|
|
|
CP0407447
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]propane-1-sulfonamide
Show/Hide
|
C22H34N4O2S2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0414596
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-2,2,2-trifluoroacetamide
Show/Hide
|
C21H27F3N4OS
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0420075
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-sulfonamide
Show/Hide
|
C23H30N4O2S3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0420079
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C24H30N4OS2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0507842
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea
Show/Hide
|
C22H33N5OS
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0045725
|
(4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0406076
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperidin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C28H31N3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0502075
|
1,6-dimethyl-5-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C28H32N4O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0505428
|
5-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0432750
|
N-[3-[4-[4-[cyclohexylmethylsulfonyl(methyl)amino]butyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
|
C24H40N4O3S
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0402937
|
ethyl 4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]piperidine-1-carboxylate
Show/Hide
|
C21H30N4O2S
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0432149
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]methanesulfonamide
Show/Hide
|
C20H30N4O2S2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0388496
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1-ethyl-1-methylurea
Show/Hide
|
C23H35N5OS
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0432151
|
1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-phenylurea
Show/Hide
|
C26H33N5OS
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0451760
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]propanamide
Show/Hide
|
C22H32N4OS
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0578946
|
(3-chloro-4-fluorophenyl)-[4-[[(6-pyrazol-1-ylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C22H23ClFN5O
|
1
|
| 1 |
Ki = 1.54 nM
|
|
|
|
CP0089820
|
1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone O-methyl oxime
Show/Hide
|
C29H32N6O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0502072
|
5-[2-[2,2-dimethyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C28H32N4O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0402331
|
3-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C22H23FN4S
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0468921
|
3-[4-[2-(5-fluoro-1H-indol-3-yl)ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C21H21FN4S
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0453904
|
1,5-bis-[3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-ethyl]phenoxy]pentane
Show/Hide
|
C43H56N4O4
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0446080
|
CHEMBL3920252
Show/Hide
|
C26H32N4OS
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0160735
|
OXITRIPTAN
Show/Hide
|
C11H12N2O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0312260
|
2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8-diol
Show/Hide
|
C16H26N2O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0416177
|
(3S)-2-[7-[4-(2-methylsulfanylphenyl)piperazin-1-yl]heptanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C28H38N4O2S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0867161
|
1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
Show/Hide
|
C22H31ClN2O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0056386
|
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Show/Hide
|
C21H21ClN4OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0548362
|
Revospirone
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C18H21N5O3S
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1
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| 1 |
Ki = 2 nM
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CP0501834
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2-[6-[4-(2-Methylthiophenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline
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C26H35N3OS
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1
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| 1 |
Ki = 2.04 nM
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CP0497873
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7-methoxy-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]quinolin-2-amine
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C23H28N4O2
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1
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| 1 |
Ki = 2.1 nM
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CP0420132
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]pyridine-3-carboxamide
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C25H31N5OS
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1
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| 1 |
Ki = 2.1 nM
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CP0512492
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]butanamide
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C23H34N4OS
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1
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| 1 |
Ki = 2.1 nM
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CP0463820
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
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C24H30N4O2S
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1
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| 1 |
Ki = 2.2 nM
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CP0407444
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3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-di(propan-2-yl)urea
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C26H41N5OS
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1
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| 1 |
Ki = 2.3 nM
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CP0505002
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1-(3-methoxyphenethyl)-4-(2-methoxyphenyl)piperazine
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C20H26N2O2
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1
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| 1 |
Ki = 2.4 nM
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CP0538636
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6-methoxy-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]quinolin-2-amine
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C26H34N4O2
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1
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| 1 |
Ki = 2.6 nM
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CP0118796
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Cariprazine
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C21H32Cl2N4O
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2
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| 1 |
Ki = 2.6 nM
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| 2 |
Ki = 3.1 nM
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CP0554504
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3-[4-(4-phenylpiperazin-1-yl)butyl]-1,3-benzoxazine-2,4-dione
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C22H25N3O3
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1
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| 1 |
Ki = 2.8 nM
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CP0402935
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-N-methylthiophene-2-sulfonamide
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C24H32N4O2S3
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1
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| 1 |
Ki = 2.9 nM
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CP0407445
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-2-methoxyacetamide
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C22H32N4O2S
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1
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| 1 |
Ki = 3 nM
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CP0540390
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2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
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C23H29N3O4S
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1
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| 1 |
Ki = 3 nM
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CP0563462
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2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexoxy]benzamide
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C24H33N3O3
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1
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| 1 |
Ki = 3 nM
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CP0568316
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2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
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C25H30N6O
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1
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| 1 |
Ki = 3 nM
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CP0446892
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1-methyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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C27H30N4O
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1
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| 1 |
Ki = 3.162 nM
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CP0547088
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2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexyl]isoindoline
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C25H33N3O2
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1
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| 1 |
Ki = 3.2 nM
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CP0571673
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3-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-1,3-benzoxazine-2,4-dione
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C23H27N3O4
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1
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| 1 |
Ki = 3.2 nM
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CP0452642
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2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline
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C28H39N3O
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1
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| 1 |
Ki = 3.7 nM
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CP0463824
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-4-methylbenzenesulfonamide
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C26H34N4O2S2
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1
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| 1 |
Ki = 3.9 nM
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CP0386021
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6-chloro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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C26H27ClN4O
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1
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| 1 |
Ki = 3.981 nM
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CP0406074
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1,6-dimethyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
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C28H32N4O
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1
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| 1 |
Ki = 3.981 nM
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CP0437527
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5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
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C28H31FN4O
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1
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| 1 |
Ki = 3.981 nM
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CP0434646
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(2S)-1-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
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C21H30Cl2N4O2
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1
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| 1 |
Ki = 4 nM
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CP0037955
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METHIOTHEPIN
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C20H24N2S2
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1
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| 1 |
Ki = 4 nM
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CP0462115
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1,1-dioxo-2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
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C26H30N4O3S
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1
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| 1 |
Ki = 4 nM
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CP0473055
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(1R,2S,6R,7S)-4-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
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C26H37N3O3
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1
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| 1 |
Ki = 4 nM
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CP0548127
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2-[5-[4-(3-methoxyphenyl)piperazin-1-yl]pentoxy]benzamide
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C23H31N3O3
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1
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| 1 |
Ki = 4 nM
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CP0542762
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2-N-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
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C19H28Cl2N8
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1
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| 1 |
Ki = 4 nM
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CP0568014
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2-N-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
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C20H32N8O
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1
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| 1 |
Ki = 4 nM
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CP0486719
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8-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-8-azaspiro[4.5]decane-7,9-dione
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C28H39ClN2O2
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1
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| 1 |
Ki = 4.3 nM
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CP0490610
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7-methoxy-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinolin-2-amine
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C25H32N4O2
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1
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| 1 |
Ki = 4.6 nM
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CP0513237
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3-chloro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
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C19H23ClN2O3S2
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1
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| 1 |
Ki = 5 nM
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CP0864251
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1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
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C24H36Cl2N2O3
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1
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| 1 |
Ki = 5 nM
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CP0408250
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5-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
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C27H32N4O4S
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1
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| 1 |
Ki = 5 nM
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CP0445925
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5-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
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C27H31N5O2S
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1
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| 1 |
Ki = 5 nM
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CP0473056
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3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-benzoxazol-2-one
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C24H28N4O2S
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1
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| 1 |
Ki = 5 nM
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CP0571683
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2-N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
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C18H26Cl2N8
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1
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| 1 |
Ki = 5 nM
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CP0039091
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N-[3-[4-[4-(cyclohexylmethylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide
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C23H38N4O3S
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1
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| 1 |
Ki = 5.1 nM
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CP0522135
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1-(2-methoxyphenyl)-4-pentylpiperazine
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C16H26N2O
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1
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| 1 |
Ki = 5.16 nM
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CP0407443
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3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1-methyl-1-phenylurea
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C27H35N5OS
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1
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| 1 |
Ki = 5.2 nM
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CP0456300
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1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-benzylurea
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C27H35N5OS
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1
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| 1 |
Ki = 5.3 nM
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CP0517451
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N-[[4-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]furan-2-carboxamide
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C24H30N4O2S
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1
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| 1 |
Ki = 5.3 nM
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CP0486717
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N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-1-carboxamide
Show/Hide
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C24H36ClN3O
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1
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| 1 |
Ki = 5.3 nM
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CP0401239
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1-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]propyl]-3-methyl-5,5-diphenylimidazolidine-2,4-dione
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C31H36N4O3
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1
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| 1 |
Ki = 5.5 nM
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CP0042927
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7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
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C23H27Cl2N3O2
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2
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| 1 |
Ki = 5.6 nM
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| 2 |
Ki = 30 nM
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CP0446003
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
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C26H38N4OS
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1
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| 1 |
Ki = 5.6 nM
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CP0455706
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5-fluoro-3-[2-[4-[2-(3-fluorophenyl)phenyl]piperazin-1-yl]ethyl]-1H-indole
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C26H25F2N3
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1
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| 1 |
Ki = 5.6 nM
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CP0059583
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1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one
Show/Hide
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C19H23N5O3S
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2
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| 1 |
Ki = 6 nM
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| 2 |
Ki = 7.9 nM
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CP0396073
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4-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 6 nM
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CP0396619
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5-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 6 nM
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CP0466249
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4-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
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C27H31N5O2S
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1
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| 1 |
Ki = 6 nM
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CP0548406
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1,1-dioxo-2-[5-(4-pyrimidin-2-ylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
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C20H25N5O3S
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1
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| 1 |
Ki = 6 nM
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CP0545014
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2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C26H31N5O
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1
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| 1 |
Ki = 6 nM
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CP0434333
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5-fluoro-3-[3-[4-[4-fluoro-2-(1H-pyrazol-4-yl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C24H25F2N5
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1
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| 1 |
Ki = 6.3 nM
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CP0457198
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1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-methyl-5,5-diphenylimidazolidine-2,4-dione
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C30H34N4O3
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1
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| 1 |
Ki = 6.5 nM
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CP0486718
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CHEMBL4762024
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C27H37ClN2O2
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1
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| 1 |
Ki = 6.6 nM
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CP0379280
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2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
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C28H30N4O4S
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1
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| 1 |
Ki = 6.7 nM
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CP0040625
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N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]acetamide
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C23H32N4O3S
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1
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| 1 |
Ki = 6.8 nM
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CP0388449
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6-Amino-2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
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C27H30N4O3
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1
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| 1 |
Ki = 6.8 nM
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CP0416052
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4-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 7 nM
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CP0427793
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(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazolidine-2,4-dione
Show/Hide
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C27H34N4O5
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1
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| 1 |
Ki = 7 nM
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CP0562769
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2-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C17H24Cl2N8
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1
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| 1 |
Ki = 7 nM
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CP0568318
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2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C22H27Cl2N5O
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1
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| 1 |
Ki = 7 nM
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CP0420085
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4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexan-1-amine
Show/Hide
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C19H28N4S
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1
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| 1 |
Ki = 7.2 nM
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CP0572401
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2-[5-[4-(3-methoxyphenyl)piperazin-1-yl]pentyl]isoindole-1,3-dione
Show/Hide
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C24H29N3O3
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1
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| 1 |
Ki = 7.2 nM
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CP0446002
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1H-indole-2-carboxamide
Show/Hide
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C28H33N5OS
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1
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| 1 |
Ki = 7.6 nM
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CP0494742
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5-(Dimethylamino)-2-[5-[4-(2-methoxyphenyl)-1-piperazinyl]pentyl]-1H-isoindole-1,3(2H)-dione
Show/Hide
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C26H34N4O3
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1
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| 1 |
Ki = 7.8 nM
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CP0408251
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4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylisoquinoline
Show/Hide
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C29H34N4O2S2
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1
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| 1 |
Ki = 8 nM
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CP0487624
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4-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H31N5O2S
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1
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| 1 |
Ki = 8 nM
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CP0414548
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzenesulfonamide
Show/Hide
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C23H30N4O2S2
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1
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| 1 |
Ki = 8 nM
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CP0492230
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5-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(4-propan-2-ylphenyl)pentanamide;hydrochloride
Show/Hide
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C25H36ClN3O2
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1
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| 1 |
Ki = 8 nM
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CP0450959
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5-fluoro-3-[3-[4-[2-(3-fluorophenyl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H27F2N3
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1
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| 1 |
Ki = 8.1 nM
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CP0459679
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4-(2-Methylthiophenyl)-N-(4-pyridinylmethyl)-1-piperazinehexanamide
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C23H32N4OS
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1
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| 1 |
Ki = 8.2 nM
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CP0485520
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5-fluoro-3-[3-[4-(4-fluoro-2-thiophen-3-ylphenyl)piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C25H25F2N3S
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1
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| 1 |
Ki = 8.4 nM
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CP0564673
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2-[5-(4-Phenyl-piperazin-1-yl)-pentyl]-isoindole-1,3-dione
Show/Hide
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C23H27N3O2
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1
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| 1 |
Ki = 8.5 nM
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CP0425240
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6-[(2R)-2-hydroxy-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propoxy]-2-methyl-4H-1,4-benzoxazin-3-one
Show/Hide
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C29H33N3O5
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1
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| 1 |
Ki = 8.7 nM
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CP0407909
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N-[3-[4-[4-(cyclohexylmethylsulfonylamino)butyl]piperazin-1-yl]phenyl]cyclopropanecarboxamide
Show/Hide
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C25H40N4O3S
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1
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| 1 |
Ki = 8.9 nM
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CP0445255
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4-fluoro-N-[1-(2-phenoxyethyl)pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C18H21FN2O3S
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1
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| 1 |
Ki = 9 nM
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CP0399639
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7-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]heptan-1-one
Show/Hide
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C33H46N4O2
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1
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| 1 |
Ki = 9 nM
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CP0396074
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5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylquinoline
Show/Hide
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C26H28N4O2S2
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1
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| 1 |
Ki = 9 nM
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CP0429636
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2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C27H31N3O3S
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1
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| 1 |
Ki = 9 nM
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CP0109693
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N-[3-[4-[4-(2-methylpropylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide
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C20H34N4O3S
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1
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| 1 |
Ki = 9.2 nM
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CP0394360
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1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine
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C18H22N2S
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1
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| 1 |
Ki = 9.5 nM
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CP0407907
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N-[3-[4-[4-[methyl(2-methylpropylsulfonyl)amino]butyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
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C21H36N4O3S
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1
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| 1 |
Ki = 9.7 nM
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CP0432751
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N-[3-[4-[[1-(cyclohexylmethylsulfonyl)piperidin-4-yl]methyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
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C25H40N4O3S
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1
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| 1 |
Ki = 10 nM
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CP0453912
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4-fluoro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C19H23FN2O3S2
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1
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| 1 |
Ki = 10 nM
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CP0486997
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2,5-difluoro-N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C22H26F2N2O3S
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1
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| 1 |
Ki = 10 nM
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CP0416050
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5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H30N4O2S2
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1
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| 1 |
Ki = 10 nM
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CP0538566
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2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexylsulfanyl]-1,3-benzoxazole
Show/Hide
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C24H28N4OS2
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1
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| 1 |
Ki = 10 nM
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CP0467727
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2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C24H31N3O4S
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2
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| 1 |
Ki = 10 nM
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| 2 |
Ki = 91 nM
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CP0558695
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2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-isoindole-1,3-dione
Show/Hide
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C22H25N3O2
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1
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| 1 |
Ki = 10 nM
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CP0459678
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[4-[[6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]hexanoylamino]methyl]phenyl] methanesulfonate
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C25H35N3O4S2
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1
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| 1 |
Ki = 10.3 nM
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CP0510438
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1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2-phenylpyridazine-3,6-dione
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C25H30N4O3
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1
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| 1 |
Ki = 10.96 nM
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CP0388495
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CHEMBL3933256
Show/Hide
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C24H31N5O2S2
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1
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| 1 |
Ki = 11 nM
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CP0491001
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2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C23H28N6OS
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1
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| 1 |
Ki = 11 nM
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CP0506463
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1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
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C26H27N3O
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1
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| 1 |
Ki = 11.5 nM
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CP0522720
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N-benzyl-6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]hexanamide
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C24H33N3OS
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1
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| 1 |
Ki = 12 nM
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CP0042717
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(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
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C21H31N5O2
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6
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| 1 |
Ki = 12 nM
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| 2 |
Ki = 20 nM
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| 3 |
Ki = 21 nM
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| 4 |
Ki = 22 nM
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| 5 |
Ki = 32.2 nM
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| 6 |
Ki = 34.3 nM
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CP0411733
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(3S)-2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C27H36N4O3
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1
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| 1 |
Ki = 12 nM
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CP0420130
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1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-pyridin-3-ylurea
Show/Hide
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C25H32N6OS
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1
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| 1 |
Ki = 12 nM
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CP0390936
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5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylquinoline
Show/Hide
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C29H34N4O2S2
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1
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| 1 |
Ki = 12 nM
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CP0472430
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4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
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C28H32N4O2S2
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1
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| 1 |
Ki = 12 nM
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CP0432718
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2-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H28FN3O3S
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1
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| 1 |
Ki = 12 nM
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CP0420924
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(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]imidazolidine-2,4-dione
Show/Hide
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C23H28N6O4
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1
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| 1 |
Ki = 12 nM
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CP0525902
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(1S,2R,6S,7R)-4-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C25H34ClN3O2
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1
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| 1 |
Ki = 12 nM
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CP0542758
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2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C28H37N9O
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1
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| 1 |
Ki = 12 nM
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CP0542761
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2-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C19H30N8O
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1
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| 1 |
Ki = 12 nM
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CP0394364
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5-fluoro-3-[3-[4-(4-fluoro-2-phenylphenyl)piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H27F2N3
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2
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| 1 |
Ki = 12 nM
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| 2 |
Ki = 28 nM
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CP0501836
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N-benzyl-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide
Show/Hide
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C24H33N3O2
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1
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| 1 |
Ki = 13 nM
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CP0471418
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinolin-2-amine
Show/Hide
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C23H28N4O
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1
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| 1 |
Ki = 13 nM
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CP0234687
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4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione
Show/Hide
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C19H29N5O2
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1
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| 1 |
Ki = 13 nM
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CP0394236
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N-[3-[4-[[1-(4-fluorophenyl)sulfonylpiperidin-4-yl]methyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
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C24H31FN4O3S
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1
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| 1 |
Ki = 13 nM
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CP0453914
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N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
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C20H26N2O3S2
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1
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| 1 |
Ki = 13 nM
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CP0396076
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5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H30N4O2S2
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1
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| 1 |
Ki = 13 nM
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CP0450842
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5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H30N4O2S2
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1
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| 1 |
Ki = 13 nM
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CP0467698
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5-fluoro-3-[3-[4-(2-phenylphenyl)piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H28FN3
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1
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| 1 |
Ki = 13 nM
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CP0432567
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1,1-dioxo-2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
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C22H28N4O3S
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1
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| 1 |
Ki = 13 nM
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CP0424512
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(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]imidazolidine-2,4-dione
Show/Hide
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C26H32N4O5
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1
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| 1 |
Ki = 13 nM
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CP0543385
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1,1-dioxo-2-[5-(4-pyridin-2-ylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
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C21H26N4O3S
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1
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| 1 |
Ki = 13 nM
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CP0548363
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2-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]isoindole-1,3-dione
Show/Hide
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C22H25N3O3
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1
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| 1 |
Ki = 13 nM
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CP0411591
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3-methyl-5,5-diphenyl-1-[5-(4-phenylpiperazin-1-yl)pentyl]imidazolidine-2,4-dione;hydrochloride
Show/Hide
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C31H36N4O2
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1
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| 1 |
Ki = 13.2 nM
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CP0862690
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1-[2-(2-Methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
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C17H21ClN2S
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1
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| 1 |
Ki = 14 nM
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CP0418456
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-7-sulfonamide
Show/Hide
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C22H24Cl2N4O2S
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1
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| 1 |
Ki = 14 nM
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CP0542060
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(2S)-1-[6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C22H34N4O2S
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1
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| 1 |
Ki = 14 nM
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CP0452857
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1-[(3S)-3-(piperidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-7-[4-(2-propan-2-ylphenyl)piperazin-1-yl]heptan-1-one
Show/Hide
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C35H50N4O2
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1
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| 1 |
Ki = 14 nM
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CP0391293
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5-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H31N5O2S
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1
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| 1 |
Ki = 14 nM
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CP0445918
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3-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C26H29N5O2S2
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1
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| 1 |
Ki = 14 nM
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CP0542419
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N-(4-butan-2-ylphenyl)-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
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C26H38ClN3O2
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1
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| 1 |
Ki = 14 nM
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CP0528199
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-6-nitroquinolin-2-amine
Show/Hide
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C22H25N5O3
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1
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| 1 |
Ki = 14.2 nM
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CP0552960
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3-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-1,1-dimethylurea
Show/Hide
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C22H34ClN3O
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1
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| 1 |
Ki = 14.5 nM
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CP0496197
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5-(Dimethylamino)-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1H-isoindole-1,3(2H)-dione
Show/Hide
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C23H28N4O3
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1
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| 1 |
Ki = 15 nM
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CP0446000
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N-[[4-[[4-(6-chloro-1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]furan-2-carboxamide
Show/Hide
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C24H29ClN4O2S
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1
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| 1 |
Ki = 15 nM
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CP0451761
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N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]morpholine-4-carboxamide
Show/Hide
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C24H35N5O2S
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1
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| 1 |
Ki = 15 nM
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CP0396080
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5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H30N4O2S2
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1
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| 1 |
Ki = 15 nM
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CP0445915
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5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C28H32N4O2S2
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1
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| 1 |
Ki = 15 nM
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CP0394365
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5-fluoro-3-[3-[4-[5-fluoro-2-(3-fluorophenyl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H26F3N3
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1
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| 1 |
Ki = 15 nM
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CP0412084
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5-fluoro-3-[3-[4-[4-fluoro-2-(furan-3-yl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C25H25F2N3O
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1
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| 1 |
Ki = 15 nM
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CP0497898
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1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
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C27H31N3O
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1
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| 1 |
Ki = 16 nM
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CP0416178
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(3S)-2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C26H32Cl2N4O2
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1
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| 1 |
Ki = 16 nM
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CP0410884
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1-[(3S)-3-(morpholine-4-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-7-[4-(2-phenylphenyl)piperazin-1-yl]heptan-1-one
Show/Hide
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C37H46N4O3
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1
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| 1 |
Ki = 16 nM
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CP0452855
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(2S)-1-[7-[4-(2-propan-2-ylphenyl)piperazin-1-yl]heptanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C25H40N4O2
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1
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| 1 |
Ki = 16 nM
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CP0452856
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1-[(3S)-3-(piperidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-6-[4-(2-propan-2-ylphenyl)piperazin-1-yl]hexan-1-one
Show/Hide
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C34H48N4O2
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1
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| 1 |
Ki = 16 nM
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CP0396077
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3-[4-[2-[(2R)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C26H29N5O2S2
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1
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| 1 |
Ki = 16 nM
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CP0466254
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4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H28N4O2S2
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1
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| 1 |
Ki = 16 nM
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CP0484413
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3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1H-benzimidazol-2-one
Show/Hide
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C24H29N5OS
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1
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| 1 |
Ki = 16 nM
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CP0512457
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N-(3-tert-butylphenyl)-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
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C26H38ClN3O2
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1
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| 1 |
Ki = 16 nM
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CP0548407
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2-[5-(4-naphthalen-1-ylpiperazin-1-yl)pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C26H29N3O3S
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1
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| 1 |
Ki = 16 nM
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CP0558696
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1,1-dioxo-2-[5-(4-phenylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C22H27N3O3S
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1
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| 1 |
Ki = 16 nM
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CP0418454
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-7-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
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1
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| 1 |
Ki = 17 nM
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CP0472348
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1-[(2S)-2-(morpholine-4-carbonyl)pyrrolidin-1-yl]-7-[4-(2-propan-2-ylphenyl)piperazin-1-yl]heptan-1-one
Show/Hide
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C29H46N4O3
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1
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| 1 |
Ki = 17 nM
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CP0568317
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2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C23H28F3N5O
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1
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| 1 |
Ki = 17 nM
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CP0408129
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N-[3-[4-[4-[(4-fluorophenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
|
C22H29FN4O3S
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1
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| 1 |
Ki = 18 nM
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CP0381348
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3-chloro-N-[[1-[2-(2-methylsulfanylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C21H27ClN2O3S2
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1
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| 1 |
Ki = 18 nM
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CP0411608
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(3S)-2-[5-[4-(2-methylsulfanylphenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C26H34N4O2S
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1
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| 1 |
Ki = 18 nM
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CP0399642
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6-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]hexan-1-one
Show/Hide
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C32H44N4O2
|
1
|
| 1 |
Ki = 18 nM
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CP0086335
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4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H30N4O2S2
|
1
|
| 1 |
Ki = 18 nM
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CP0446202
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5-fluoro-3-[3-[4-[3-fluoro-2-(3-fluorophenyl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H26F3N3
|
1
|
| 1 |
Ki = 18 nM
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CP0348615
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2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-hexyl]-isoindole-1,3-dione
Show/Hide
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C25H28N4O2S
|
1
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| 1 |
Ki = 18 nM
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CP0530032
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(1S,2R,6S,7R)-4-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C25H34ClN3O2
|
1
|
| 1 |
Ki = 18 nM
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CP0565308
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3-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-benzoxazine-2,4-dione
Show/Hide
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C25H31N3O4
|
1
|
| 1 |
Ki = 18 nM
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CP0569929
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2-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C24H32N6O
|
1
|
| 1 |
Ki = 18 nM
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CP0506462
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1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pentyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
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C24H29N5O
|
1
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| 1 |
Ki = 18.1 nM
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CP0459680
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4-(2-Methoxyphenyl)-N-(4-pyridinylmethyl)-1-piperazinehexanamide
Show/Hide
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C23H32N4O2
|
1
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| 1 |
Ki = 19 nM
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CP0399641
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6-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(3S)-3-(piperidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]hexan-1-one
Show/Hide
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C37H46N4O2
|
1
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| 1 |
Ki = 19 nM
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CP0853989
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5-(4-Fluorophenyl)-3-{2-hydroxy-3-[4-(naphthalen-1-yl)-piperazin-1-yl]propyl}-5-methylimidazolidine-2,4-dione
Show/Hide
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C27H29FN4O3
|
1
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| 1 |
Ki = 19 nM
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CP0459145
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2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C24H31N3O4S
|
1
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| 1 |
Ki = 19 nM
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CP0417068
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3-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C27H36N4O2
|
1
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| 1 |
Ki = 19 nM
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CP0569927
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2-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C23H28Cl2N6
|
1
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| 1 |
Ki = 19 nM
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CP0487766
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(3S)-2-[7-[4-(2-propan-2-ylphenyl)piperazin-1-yl]heptanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C30H42N4O2
|
1
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| 1 |
Ki = 20 nM
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CP0873148
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1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
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C20H27Cl3N2O
|
1
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| 1 |
Ki = 20 nM
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CP0311502
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1,1-dioxo-2-[6-(4-phenylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
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C23H29N3O3S
|
1
|
| 1 |
Ki = 20 nM
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CP0417090
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2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
|
1
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| 1 |
Ki = 20 nM
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CP0526779
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6-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C26H32N4O2S
|
1
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| 1 |
Ki = 20 nM
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CP0548333
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3-[5-[4-(3-methoxyphenyl)piperazin-1-yl]pentyl]-1,3-benzoxazine-2,4-dione
Show/Hide
|
C24H29N3O4
|
1
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| 1 |
Ki = 20 nM
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CP0486996
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N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H26N2O3S2
|
1
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| 1 |
Ki = 21 nM
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CP0432719
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2-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
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| 1 |
Ki = 21 nM
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CP0425221
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5-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(3-propan-2-ylphenyl)pentanamide;hydrochloride
Show/Hide
|
C25H36ClN3O2
|
1
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| 1 |
Ki = 21 nM
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CP0425222
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N-(4-tert-butylphenyl)-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
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C26H38ClN3O2
|
1
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| 1 |
Ki = 21 nM
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CP0543362
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1,1-dioxo-2-[5-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
Ki = 21 nM
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CP0571674
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2-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propoxy]benzamide
Show/Hide
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C21H27N3O3
|
1
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| 1 |
Ki = 21 nM
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CP0576365
|
1-(3-chlorophenyl)-4-[6-(sulfamoylamino)hexyl]piperazine
Show/Hide
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C16H27ClN4O2S
|
1
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| 1 |
Ki = 21 nM
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CP0459681
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2-[6-[4-(2-(1-Methylethyl)phenyl)-1-piperazinyl]-1-oxohexyl]isoindoline
Show/Hide
|
C27H37N3O
|
1
|
| 1 |
Ki = 22 nM
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CP0522774
|
6-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinolin-2-amine
Show/Hide
|
C24H30N4O2
|
1
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| 1 |
Ki = 22 nM
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CP0485850
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N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]cyclopropanecarboxamide
Show/Hide
|
C25H34N4O3S
|
1
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| 1 |
Ki = 22 nM
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CP0439674
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1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C26H29N3O
|
1
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| 1 |
Ki = 22 nM
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CP0445256
|
4-fluoro-N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C22H27FN2O3S
|
1
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| 1 |
Ki = 22 nM
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CP0486998
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4-fluoro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H25FN2O3S
|
1
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| 1 |
Ki = 22 nM
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CP0384573
|
1-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
|
C30H32N4O
|
1
|
| 1 |
Ki = 22 nM
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CP0417089
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1-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C29H35N3O2
|
1
|
| 1 |
Ki = 22 nM
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CP0525896
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzamide
Show/Hide
|
C24H30N4OS
|
1
|
| 1 |
Ki = 22 nM
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CP0525901
|
(1R,2S,6R,7S)-4-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H34F3N3O2
|
1
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| 1 |
Ki = 22 nM
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CP0511830
|
2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]isoindole-1,3-dione
Show/Hide
|
C25H31N3O3
|
1
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| 1 |
Ki = 22 nM
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CP0484397
|
CHEMBL4788140
Show/Hide
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C28H35ClN2O2
|
1
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| 1 |
Ki = 22.8 nM
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CP0426093
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N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-8-sulfonamide
Show/Hide
|
C24H29N3O3S
|
1
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| 1 |
Ki = 23 nM
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CP0418452
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-3-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
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| 1 |
Ki = 23 nM
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CP0434356
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6-chloro-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-3-sulfonamide
Show/Hide
|
C22H23Cl3N4O2S
|
1
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| 1 |
Ki = 23 nM
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CP0484019
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(2S)-1-[7-[4-(2-methylsulfanylphenyl)piperazin-1-yl]heptanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C23H36N4O2S
|
1
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| 1 |
Ki = 23 nM
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CP0511148
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3-chloro-N-[1-[2-(2-phenylphenoxy)ethyl]azetidin-3-yl]benzenesulfonamide
Show/Hide
|
C23H23ClN2O3S
|
1
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| 1 |
Ki = 23 nM
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CP0472438
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4-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
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| 1 |
Ki = 23 nM
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CP0429637
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2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H28N4O3S2
|
1
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| 1 |
Ki = 23 nM
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CP0382640
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1-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-3,5-dimethyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H36N4O3
|
1
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| 1 |
Ki = 23.3 nM
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CP0485849
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N-[3-[4-[4-(propan-2-ylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
|
C19H32N4O3S
|
1
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| 1 |
Ki = 24 nM
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CP0876492
|
3-Methoxy-5-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-9H-xanthen-9-one hydrochloride
Show/Hide
|
C26H27ClN2O4
|
1
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| 1 |
Ki = 24 nM
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CP0415732
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
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| 1 |
Ki = 24 nM
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CP0450839
|
3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
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| 1 |
Ki = 24 nM
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CP0487358
|
3-[4-[2-[(2R)-1-quinolin-4-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
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| 1 |
Ki = 24 nM
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CP0391600
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1,1-dioxo-2-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C21H27N5O3S
|
1
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| 1 |
Ki = 24 nM
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CP0486724
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(1S,2S,6R,7R)-4-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C28H37ClN2O2
|
1
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| 1 |
Ki = 24.9 nM
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CP0453618
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-6-sulfonamide
Show/Hide
|
C22H24Cl2N4O2S
|
1
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| 1 |
Ki = 25 nM
|
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CP0416051
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
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| 1 |
Ki = 25 nM
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CP0446201
|
5-fluoro-3-[2-[4-[2-(2-fluorophenyl)phenyl]piperazin-1-yl]ethyl]-1H-indole
Show/Hide
|
C26H25F2N3
|
1
|
| 1 |
Ki = 25 nM
|
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CP0526645
|
1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C26H25N3O
|
1
|
| 1 |
Ki = 26 nM
|
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CP0510464
|
3-benzyl-1-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C28H39ClN4O3
|
1
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| 1 |
Ki = 26 nM
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CP0487764
|
(3S)-2-[6-[4-(2-phenylphenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C32H38N4O2
|
1
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| 1 |
Ki = 26 nM
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CP0482089
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2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
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| 1 |
Ki = 26 nM
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CP0396620
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4-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
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| 1 |
Ki = 27 nM
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CP0530031
|
(1R,2S,6R,7S)-4-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H34N4O2S
|
1
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| 1 |
Ki = 27 nM
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CP0372863
|
6-methoxy-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]quinolin-2-amine
Show/Hide
|
C23H28N4O2
|
1
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| 1 |
Ki = 28 nM
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CP0381395
|
5-chloro-N-[1-[2-(2,3-dichlorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H17Cl3N2O3S2
|
1
|
| 1 |
Ki = 28 nM
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CP0541049
|
3-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]azetidin-3-yl]benzenesulfonamide
Show/Hide
|
C20H25FN2O3S
|
1
|
| 1 |
Ki = 28 nM
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CP0396615
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3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
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| 1 |
Ki = 28 nM
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CP0384574
|
2-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C30H35N3O3
|
1
|
| 1 |
Ki = 28 nM
|
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CP0452641
|
[4-[[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanoylamino]methyl]phenyl] methanesulfonate
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
Ki = 29 nM
|
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CP0430723
|
5-(Dimethylamino)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-1-naphthalenesulfonamide
Show/Hide
|
C26H34N4O3S
|
1
|
| 1 |
Ki = 29 nM
|
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CP0448728
|
4-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
|
| 1 |
Ki = 29 nM
|
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CP0471323
|
tert-butyl 3-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanoylamino]benzoate;hydrochloride
Show/Hide
|
C27H38ClN3O4
|
1
|
| 1 |
Ki = 29 nM
|
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CP0548405
|
2-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C22H25Cl2N3O3S
|
1
|
| 1 |
Ki = 29 nM
|
|
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CP0369765
|
6-[4-(2-fluorophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C26H34FN3O
|
1
|
| 1 |
Ki = 29.2 nM
|
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CP0508202
|
N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-2-carboxamide
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
Ki = 30 nM
|
|
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CP0891182
|
1-(2-Phenylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C16H19ClN2S
|
1
|
| 1 |
Ki = 30 nM
|
|
|
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CP0375468
|
4-fluoro-N-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H29FN2O3S
|
1
|
| 1 |
Ki = 30 nM
|
|
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CP0475051
|
4-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31F3N4O2S
|
1
|
| 1 |
Ki = 30 nM
|
|
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CP0497330
|
2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-phenylphthalazine-1,4-dione
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
Ki = 30.2 nM
|
|
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CP0453916
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3-chloro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
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C21H27ClN2O3S
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1
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| 1 |
Ki = 31 nM
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CP0722890
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1-[2-(2,3-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
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C18H23ClN2S
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1
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| 1 |
Ki = 31 nM
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CP0546805
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N-(2-hydroxyphenyl)-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
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C22H30ClN3O3
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1
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| 1 |
Ki = 31 nM
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CP0545013
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2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]cyclohexyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C24H30ClN5O
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1
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| 1 |
Ki = 31 nM
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CP0433625
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4-fluoro-N-[(3S)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C24H25FN2O3S
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1
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| 1 |
Ki = 32 nM
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CP0448727
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4-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
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C26H31ClN4O2S
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1
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| 1 |
Ki = 32 nM
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CP0873149
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1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
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C24H36Cl2N2O3
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1
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| 1 |
Ki = 32 nM
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CP0384570
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1-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
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C26H30N4O
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1
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| 1 |
Ki = 32 nM
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CP0530033
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(1R,2S,6R,7S)-4-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C25H33Cl2N3O2
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1
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| 1 |
Ki = 32 nM
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CP0532783
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-methyl-N-phenylbenzenesulfonamide
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C30H36N4O2S2
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1
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| 1 |
Ki = 32 nM
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CP0941206
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Paynantheine
Show/Hide
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C23H28N2O4
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1
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| 1 |
Ki = 32 nM
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CP0542766
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2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C27H35N9
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1
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| 1 |
Ki = 32 nM
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CP0471419
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]quinolin-2-amine
Show/Hide
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C22H26N4O
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1
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| 1 |
Ki = 33 nM
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CP0451764
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N-[4-[2-[4-(6-amino-1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
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C24H31N5O2S
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1
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| 1 |
Ki = 33 nM
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CP0418455
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-sulfonamide
Show/Hide
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C23H26Cl2N4O2S
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1
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| 1 |
Ki = 34 nM
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CP0554727
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(3S)-2-[5-[4-(2-propan-2-ylphenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C28H38N4O2
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1
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| 1 |
Ki = 34 nM
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CP0486486
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6-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(3-propan-2-ylphenyl)hexanamide;hydrochloride
Show/Hide
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C26H38ClN3O2
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1
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| 1 |
Ki = 34 nM
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CP0915073
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2-(2-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)vinyl)-1-(6-(3-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)phenoxy)-6-oxohexyl)-3,3-dimethyl-3H-indolium bromide
Show/Hide
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C50H59BrN4O5
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1
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| 1 |
Ki = 35 nM
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CP0399640
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5-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(2S)-2-(piperidine-1-carbonyl)pyrrolidin-1-yl]pentan-1-one
Show/Hide
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C31H42N4O2
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1
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| 1 |
Ki = 35 nM
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CP0410885
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1-[(2S)-2-(morpholine-4-carbonyl)pyrrolidin-1-yl]-7-[4-(2-phenylphenyl)piperazin-1-yl]heptan-1-one
Show/Hide
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C32H44N4O3
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1
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| 1 |
Ki = 35 nM
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CP0417065
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3-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
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C25H30N4O2S
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1
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| 1 |
Ki = 35 nM
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CP0569187
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4-(3-chlorophenyl)-N-[6-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2-yl)hexyl]piperazine-1-carboxamide
Show/Hide
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C23H29ClN6O2
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1
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| 1 |
Ki = 35 nM
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CP0410887
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1-[(3S)-3-(morpholine-4-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-[4-(2-phenylphenyl)piperazin-1-yl]pentan-1-one
Show/Hide
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C35H42N4O3
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1
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| 1 |
Ki = 36 nM
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CP0390940
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4-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
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C26H29N5O4S
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1
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| 1 |
Ki = 36 nM
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CP0486725
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CHEMBL4750939
Show/Hide
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C23H36ClN3O
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1
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| 1 |
Ki = 36 nM
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CP0371909
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3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quinazolin-4(3H)-one
Show/Hide
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C23H28N4O2
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1
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| 1 |
Ki = 36.31 nM
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CP0092295
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6-[4-(pyridin-2-yl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
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C25H34N4O
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1
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| 1 |
Ki = 36.4 nM
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CP0219574
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3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C26H29N5O2S2
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1
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| 1 |
Ki = 37 nM
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CP0487359
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3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C26H29N5O2S2
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1
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| 1 |
Ki = 37 nM
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CP0427792
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(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]imidazolidine-2,4-dione
Show/Hide
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C30H38N4O5
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1
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| 1 |
Ki = 37 nM
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CP0471318
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N-(4-butan-2-ylphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
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C25H36ClN3O2
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1
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| 1 |
Ki = 37 nM
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CP0513135
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(2S)-1-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C21H31ClN4O2
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1
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| 1 |
Ki = 38 nM
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CP0542141
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5-fluoro-3-[3-[4-(4-fluoro-2-thiophen-2-ylphenyl)piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C25H25F2N3S
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1
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| 1 |
Ki = 38 nM
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CP0570983
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2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butoxy]benzamide
Show/Hide
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C22H29N3O3
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1
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| 1 |
Ki = 38 nM
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CP0915741
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Speciogynine
Show/Hide
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C23H30N2O4
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1
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| 1 |
Ki = 38.5 nM
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CP0493808
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1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
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C26H27N3O
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1
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| 1 |
Ki = 39 nM
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CP0658701
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1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
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C18H23ClN2S
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1
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| 1 |
Ki = 39 nM
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CP0852401
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1-[2-(4-Fluoro-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
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C16H18ClFN2S
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1
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| 1 |
Ki = 39 nM
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CP0432153
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N-[4-[2-[4-(6-nitro-1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
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C24H29N5O4S
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1
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| 1 |
Ki = 39 nM
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CP0478914
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-1-sulfonamide
Show/Hide
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C27H32N4O2S2
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1
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| 1 |
Ki = 39 nM
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CP0568128
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6-[4-(3-chlorophenyl)piperazin-1-yl]hexylurea
Show/Hide
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C17H27ClN4O
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1
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| 1 |
Ki = 39 nM
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CP0484627
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2-[6-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline
Show/Hide
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C26H35N3O2
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1
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| 1 |
Ki = 40 nM
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CP0408128
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4-methyl-N-(4-(4-phenylpiperazin-1-yl)butyl)benzenesulfonamide
Show/Hide
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C21H29N3O2S
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1
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| 1 |
Ki = 40 nM
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CP0525971
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N-[3-[4-[4-(cyclohexylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
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C22H36N4O3S
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1
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| 1 |
Ki = 40 nM
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CP0480608
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7-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(3S)-3-(piperidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]heptan-1-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
Ki = 40 nM
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CP0475050
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5-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C27H31F3N4O2S
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1
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| 1 |
Ki = 40 nM
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CP0425229
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N-(4-tert-butylphenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
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C27H40ClN3O2
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1
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| 1 |
Ki = 40 nM
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CP0527898
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Show/Hide
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C30H33F3N4O2S2
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1
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| 1 |
Ki = 42 nM
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CP0510440
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2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-phenylphthalazine-1,4-dione
Show/Hide
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C29H32N4O3
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1
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| 1 |
Ki = 42.66 nM
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CP0522875
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N-[(4-cyanophenyl)methyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide
Show/Hide
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C25H32N4O2
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1
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| 1 |
Ki = 43 nM
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CP0478414
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1-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
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C27H31Cl2N3O
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1
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| 1 |
Ki = 43 nM
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CP0486487
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6-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(4-propan-2-ylphenyl)hexanamide;hydrochloride
Show/Hide
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C26H38ClN3O2
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1
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| 1 |
Ki = 43 nM
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CP0534678
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N-[(2-hydroxyphenyl)methyl]-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
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C23H32ClN3O3
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1
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| 1 |
Ki = 43 nM
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CP0498925
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6-Amino-2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Show/Hide
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C25H26N4O3
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1
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| 1 |
Ki = 44 nM
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CP0658702
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1-(2-p-Tolylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
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C17H21ClN2S
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1
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| 1 |
Ki = 44 nM
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CP0382373
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(2S)-1-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C22H34N4O3
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1
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| 1 |
Ki = 44 nM
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CP0414533
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3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C27H33N5OS
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1
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| 1 |
Ki = 44 nM
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CP0426091
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N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-2-carboxamide
Show/Hide
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C28H27N3O2
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1
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| 1 |
Ki = 45 nM
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CP0508203
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N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
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C22H24N2O3S2
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1
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| 1 |
Ki = 45 nM
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CP0382801
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3-benzyl-1-[5-[4-(3-methoxyphenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
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C28H38N4O3
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1
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| 1 |
Ki = 45 nM
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CP0541025
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4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]azetidin-3-yl]benzenesulfonamide
Show/Hide
|
C20H25FN2O3S
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1
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| 1 |
Ki = 45 nM
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CP0417575
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5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C26H30Cl2N4O2S
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1
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| 1 |
Ki = 45 nM
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CP0420923
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(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-3-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
Show/Hide
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C24H30N6O4
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1
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| 1 |
Ki = 45 nM
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CP0432717
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N-[4-[4-[3-(methanesulfonamido)phenyl]piperazin-1-yl]butyl]-4-methylbenzenesulfonamide
Show/Hide
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C22H32N4O4S2
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1
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| 1 |
Ki = 46 nM
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CP0447110
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1-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]azetidin-3-yl]pyrazole-4-sulfonamide
Show/Hide
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C21H24N4O3S
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1
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| 1 |
Ki = 46 nM
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CP0416668
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3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
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1
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| 1 |
Ki = 46 nM
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CP0569511
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3-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]-1,3-benzoxazine-2,4-dione
Show/Hide
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C22H25N3O4
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1
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| 1 |
Ki = 46 nM
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CP0436937
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4-methyl-N-(4-{4-[3-(propane-2-sulfonylamino)-phenyl]-piperazin-1-yl}-butyl)-benzenesulfonamide
Show/Hide
|
C24H36N4O4S2
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1
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| 1 |
Ki = 47 nM
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CP0411730
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(2S)-1-[5-[4-(2-methylsulfanylphenyl)piperazin-1-yl]pentanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C21H32N4O2S
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1
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| 1 |
Ki = 47 nM
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CP0410886
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5-[4-(2-phenylphenyl)piperazin-1-yl]-1-[(3S)-3-(piperidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]pentan-1-one
Show/Hide
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C36H44N4O2
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1
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| 1 |
Ki = 47 nM
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CP0417067
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2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
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1
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| 1 |
Ki = 47 nM
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CP0417069
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1-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C28H33N3O2
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1
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| 1 |
Ki = 47 nM
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CP0381349
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2,3-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzamide
Show/Hide
|
C25H24F2N2O2
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1
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| 1 |
Ki = 48 nM
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CP0476720
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3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
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1
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| 1 |
Ki = 48 nM
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CP0483351
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3-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C28H35N3O3S
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1
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| 1 |
Ki = 48 nM
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CP0569637
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2-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8O
|
1
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| 1 |
Ki = 48 nM
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CP0445257
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5-chloro-N-[(3R)-1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H25ClN2O3S2
|
1
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| 1 |
Ki = 49 nM
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CP0390937
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3-[4-[2-[(2S)-1-quinolin-4-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
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1
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| 1 |
Ki = 50 nM
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CP0120218
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3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]quinazolin-4-one
Show/Hide
|
C22H25ClN4O
|
1
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| 1 |
Ki = 50.12 nM
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CP0475149
|
1-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-2-phenylpyridazine-3,6-dione
Show/Hide
|
C24H27ClN4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0447109
|
2,5-difluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C24H30F2N2O3S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0411731
|
(2S)-1-[5-[4-(2-hydroxyphenyl)piperazin-1-yl]pentanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0545010
|
2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H24ClN5O
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0090070
|
6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C27H37N3OS
|
1
|
| 1 |
Ki = 52.7 nM
|
|
|
|
CP0452640
|
N-[(4-cyanophenyl)methyl]-6-[4-(2-propan-2-ylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C27H36N4O
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0689936
|
1-[2-(3,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0468980
|
(2S)-1-[7-[4-(2-phenylphenyl)piperazin-1-yl]heptanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H38N4O2
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0424508
|
(5Z)-3-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-5-[(3,4-dimethoxyphenyl)methylidene]imidazolidine-2,4-dione
Show/Hide
|
C25H28Cl2N4O4
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0572545
|
N-(3-tert-butylphenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C27H40ClN3O2
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0430963
|
1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-2-phenylpyridazine-3,6-dione
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0430724
|
5-(Dimethylamino)-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1-naphthalenesulfonamide
Show/Hide
|
C28H38N4O3S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0472682
|
5-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31ClN4O2S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0415694
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C25H27N5O2S2
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0471830
|
2-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H27Cl2N3O3S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0384692
|
1-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0473054
|
(1S,2R,6S,7R)-4-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0394232
|
N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]butanamide
Show/Hide
|
C25H36N4O3S
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0390938
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C25H27N5O2S2
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0542765
|
2-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C17H26N8
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0484588
|
[4-[[6-[4-(2-propan-2-ylphenyl)piperazin-1-yl]hexanoylamino]methyl]phenyl] methanesulfonate
Show/Hide
|
C27H39N3O4S
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0416732
|
2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H27Cl2N3O3S
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0848955
|
1-[2-(2-Methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0418453
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-4-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0397956
|
3-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H25Cl2FN4O3
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0286143
|
6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C30H43N3O
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0344729
|
6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C32H39N3O
|
1
|
| 1 |
Ki = 60.9 nM
|
|
|
|
CP0471048
|
(3S)-2-[7-[4-(2-phenylphenyl)piperazin-1-yl]heptanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C33H40N4O2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0534677
|
N-(5-tert-butyl-2-hydroxyphenyl)-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
|
C26H38ClN3O3
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0375466
|
N-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H30N2O3S
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0477204
|
5-fluoro-3-[3-[4-[4-fluoro-2-(3-fluorophenyl)phenyl]piperazin-1-yl]propyl]-1H-indole
Show/Hide
|
C27H26F3N3
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0526780
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0557796
|
3-[5-[[2-(5-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0424507
|
(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
Show/Hide
|
C28H36N6O4
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0384691
|
1-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31ClFN3O
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0560721
|
N-[(2-methoxyphenyl)methyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C25H36ClN3O3
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0462945
|
5-chloro-N-[1-(2-phenoxyethyl)pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H19ClN2O3S2
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0870586
|
1-[2-(2,4-Dimethyl-phenoxy)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0906009
|
sodium 4-(2-(2-(3-(2-(3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indolium-2-yl)vinyl)-2-(4-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentylcarbamoyl)phenylthio)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)butane-1-sulfonate chloride
Show/Hide
|
C61H76ClN5Na2O8S3
|
1
|
| 1 |
Ki = 65.8 nM
|
|
|
|
CP0399643
|
(3S)-2-[5-[4-(2-phenylphenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C31H36N4O2
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0382643
|
N-[(1S)-1-phenylethyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0391303
|
4-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0416669
|
1-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0881043
|
1-[2-(2,3-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0912453
|
1-[2-(3,4-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0718265
|
1-[2-(4-Chloro-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C16H18Cl2N2S
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0545853
|
N-(4-butan-2-ylphenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C27H40ClN3O2
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0501835
|
4-(2-Diphenyl)-N-(4-pyridinylmethyl)-1-piperazinehexanamide
Show/Hide
|
C28H34N4O
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0553045
|
N-[(2-hydroxyphenyl)methyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C24H34ClN3O3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0545009
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene 2,2-dioxide
Show/Hide
|
C25H33ClN4O2S
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0414547
|
1-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H30N4OS
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0542994
|
2-N-[5-(4-phenylpiperazin-1-yl)pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0439937
|
(3S)-2-[6-[4-(2-hydroxyphenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0447657
|
5-(Dimethylamino)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-naphthalenesulfonamide
Show/Hide
|
C25H32N4O3S
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0526778
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H32N4O2S2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0542763
|
4-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C27H33Cl2N9
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0850795
|
4-N-{1-[2-(Biphenyl-2-yloxy)ethyl]piperidin-4-yl}-isoquinolinesulfonamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0955711
|
2-Methylpropane-N-{(1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-sulfonamide
Show/Hide
|
C23H32N2O3S
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0458932
|
3,4-difluoro-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C27H28F2N2O3S
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0530888
|
N-[[4-[(dimethylamino)methyl]phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C32H42N4O
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0545006
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C26H33ClN4O
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0484398
|
(2S)-N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-2-carboxamide
Show/Hide
|
C24H36ClN3O
|
1
|
| 1 |
Ki = 74.7 nM
|
|
|
|
CP0445258
|
5-chloro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C22H23ClN2O3S2
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0717003
|
1-[2-(2,3-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0382641
|
3-benzyl-1-[5-[4-(2-fluorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H36ClFN4O2
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0419910
|
(3S)-2-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]benzoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C29H32N4O3
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0514794
|
2-[[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenyl]methyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C26H27N3O4S
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0408126
|
2-methyl-N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]propanamide
Show/Hide
|
C25H36N4O3S
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0689934
|
1-[2-(2-Chloro-4-methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H20Cl2N2S
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0689935
|
1-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0449729
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-6-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0480126
|
3-benzyl-5,5-dimethyl-1-[5-(4-phenylpiperazin-1-yl)pentyl]imidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H36N4O2
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0483352
|
3-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0337376
|
6-[4-(2-ethylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C28H39N3O
|
1
|
| 1 |
Ki = 79.2 nM
|
|
|
|
CP0406918
|
N,1-dimethyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C24H30N4O3S
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0376752
|
N-[(1R)-1-phenylethyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0381351
|
2,5-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H24F2N2O3S
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0384693
|
3-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31ClFN3O2S
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0471322
|
N-(5-tert-butyl-2-hydroxyphenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C27H40ClN3O3
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0534674
|
2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanoylamino]benzamide;hydrochloride
Show/Hide
|
C23H31ClN4O3
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0573258
|
N-[(2-methoxyphenyl)methyl]-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
|
C24H34ClN3O3
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0542757
|
2-N-[6-(4-phenylpiperazin-1-yl)hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H30N8
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0552304
|
(2R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-pyrazin-2-yloxypropan-2-ol
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
Ki = 82.9 nM
|
|
|
|
CP0526461
|
(2S)-1-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C20H28Cl2N4O2
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0416728
|
2-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0548044
|
5-(4-bromophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30BrClN4O4
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0458060
|
(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]imidazolidine-2,4-dione
Show/Hide
|
C27H34N6O4
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0382642
|
N-[[4-(methoxymethoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C31H39N3O3
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0529086
|
3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0532785
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C29H30N4O2S
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0482397
|
6-chloro-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-3-sulfonamide
Show/Hide
|
C23H25Cl3N4O2S
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0401242
|
3-[(2,4-dichlorophenyl)methyl]-1-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H32Cl4N4O2
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0453913
|
5-chloro-N-[(3S)-1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H25ClN2O3S2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0411577
|
(3S)-2-[7-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]heptanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C28H35N5O3
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0476721
|
5-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0426437
|
2-(5-methoxy-1H-indol-3-yl)-N-[[5-(3-methoxyphenyl)furan-2-yl]methyl]ethanamine
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0938821
|
sunepitron
Show/Hide
|
C17H23N5O2
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0481685
|
3,4-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H24F2N2O3S
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0534303
|
1-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-2,5-dione
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
Ki = 93.4 nM
|
|
|
|
CP0485908
|
N-[(4-cyanophenyl)methyl]-6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C25H32N4OS
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0891181
|
1-[2-(2-Chloro-4-methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H20Cl2N2OS
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0417064
|
1-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0529593
|
2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C31H37N3O
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0578872
|
N-(2-hydroxyphenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanamide;hydrochloride
Show/Hide
|
C23H32ClN3O3
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0391297
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0498535
|
CHEMBL4780335
Show/Hide
|
C24H31ClN2O2
|
1
|
| 1 |
Ki = 96.9 nM
|
|
|
|
CP0240250
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0402811
|
4-fluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0397957
|
3-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C25H31FN4O4
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0532952
|
CHEMBL4745809
Show/Hide
|
C24H35ClN2O2
|
1
|
| 1 |
Ki = 98.3 nM
|
|
|
|
CP0477244
|
3,4-difluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C24H30F2N2O3S
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0531665
|
3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-chlorophenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C30H34Cl2N4O3
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0439203
|
3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinazolin-4-one
Show/Hide
|
C22H26N4O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0912456
|
1-[2-(3-Methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0476106
|
3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-(4-methoxyphenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C25H33ClN4O5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0371905
|
2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1, 2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
|
C22H24F3N3O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0525831
|
5-chloro-N-[[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]methyl]thiophene-2-sulfonamide
Show/Hide
|
C24H27ClN2O3S2
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0445704
|
N-benzyl-6-[(2R)-2-methyl-4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0514793
|
2-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C22H26ClN3O3S
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0850603
|
5-N-{1-[2-(Biphenyl-2-yloxy)ethyl]piperidin-4-yl}-quinoline-sulfonamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0954040
|
4-N-(1-{2-[(Propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-isoquinoline sulfonamide
Show/Hide
|
C25H31N3O3S
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0538554
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[(1S)-1-phenylethyl]hexanamide
Show/Hide
|
C31H39N3O2
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0486994
|
3-chloro-N-[[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C23H31ClN2O3S
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0445705
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]hexanamide
Show/Hide
|
C37H50N4O4
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0534679
|
2-[5-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-4,4-dimethylpentoxy]pyrazine
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0501833
|
[4-[[6-[4-(2-phenylphenyl)piperazin-1-yl]hexanoylamino]methyl]phenyl] methanesulfonate
Show/Hide
|
C30H37N3O4S
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0495707
|
3-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0468102
|
(3S)-2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0445710
|
N-[(1R)-1-(4-cyanophenyl)ethyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H38N4O2
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0426411
|
5-(4-chlorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30Cl2N4O4
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0396617
|
6-fluoro-3-[1-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 111 nM
|
|
|
|
CP0390983
|
N-[3-[4-[(1-propan-2-ylsulfonylpiperidin-4-yl)methyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
|
C21H34N4O3S
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0185316
|
6-{4-[2-(dimethylamino)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C28H40N4O
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0449784
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-8-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0430722
|
6-Amino-2-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Show/Hide
|
C26H28N4O3
|
1
|
| 1 |
Ki = 116 nM
|
|
|
|
CP0909449
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-9H-xanthen-9-one hydrochloride
Show/Hide
|
C25H25ClN2O3
|
1
|
| 1 |
Ki = 117 nM
|
|
|
|
CP0899691
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-4-methyl-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0389125
|
6-fluoro-3-[1-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0426435
|
4-[5-[[2-(5-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0382069
|
5-(4-fluorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0419908
|
(2S)-1-[7-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]heptanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C23H33N5O3
|
1
|
| 1 |
Ki = 122 nM
|
|
|
|
CP0419909
|
(3S)-2-[4-[[4-(2-methylsulfanylphenyl)piperazin-1-yl]methyl]benzoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C29H32N4O2S
|
1
|
| 1 |
Ki = 122 nM
|
|
|
|
CP0417077
|
1-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H30Cl3N3O
|
1
|
| 1 |
Ki = 122 nM
|
|
|
|
CP0447115
|
3-fluoro-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C27H29FN2O3S
|
1
|
| 1 |
Ki = 123 nM
|
|
|
|
CP0098968
|
3-(3-ethylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
Ki = 123 nM
|
|
|
|
CP0452643
|
2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]isoindoline
Show/Hide
|
C30H35N3O
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0424212
|
1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-indolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0095010
|
1-[5-[4-(2-fluorophenyl)piperazin-1-yl]pentyl]-3,5-dimethyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C26H33FN4O2
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0443912
|
2-(1H-indol-3-yl)-N-[(5-phenylfuran-2-yl)methyl]ethanamine
Show/Hide
|
C21H20N2O
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0435198
|
4-[[4-(5-methoxy-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]methyl]-1H-quinolin-2-one
Show/Hide
|
C24H23N3O2
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0567510
|
tert-butyl 4-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexanoylamino]benzoate;hydrochloride
Show/Hide
|
C28H40ClN3O4
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0183577
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid ((S)-3-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-4-methoxy-phenyl)-amide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0445706
|
N-[(4-cyanophenyl)methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C31H36N4O2
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0519609
|
5-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C17H15ClN4O2S
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0557041
|
6-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]-2-methyl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C30H35N3O4
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0853986
|
3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-2-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H32N4O4
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0852965
|
3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-2-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H29N5O3
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0848958
|
1-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0438711
|
(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]imidazolidine-2,4-dione
Show/Hide
|
C30H36Cl2N4O4
|
1
|
| 1 |
Ki = 132 nM
|
|
|
|
CP0478413
|
3-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 132 nM
|
|
|
|
CP0333596
|
6-{4-[2-(methylamino)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C27H38N4O
|
1
|
| 1 |
Ki = 133 nM
|
|
|
|
CP0507071
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[(1R)-1-phenylethyl]hexanamide
Show/Hide
|
C31H39N3O2
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0424240
|
5-methoxy-3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0095011
|
3,5-dimethyl-5-phenyl-1-[5-(4-phenylpiperazin-1-yl)pentyl]imidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0435204
|
5-methoxy-3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0552305
|
8-chloro-7-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C31H33ClN2O4
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0471321
|
N-[(4-tert-butylphenyl)methyl]-5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanamide;hydrochloride
Show/Hide
|
C27H40ClN3O2
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0501837
|
N-benzyl-6-[4-(2-propan-2-ylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C26H37N3O
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0435199
|
5-ethoxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C20H22N2OS
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0435202
|
3-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-methoxy-1H-indole
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0882249
|
1-[2-(3-Methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0385629
|
N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H32N2O3S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0475930
|
2-[4-[3-[4-(4-bromophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C24H27BrClN5O3
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0424841
|
N-[4-[4-[3-(ethylsulfonylamino)phenyl]piperazin-1-yl]butyl]-4-methylbenzenesulfonamide
Show/Hide
|
C23H34N4O4S2
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0413769
|
4-fluoro-N-[[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0467984
|
(2S)-1-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C21H31FN4O2
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0390348
|
3-fluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
Ki = 143 nM
|
|
|
| 2 |
Ki = 180 nM
|
|
|
|
CP0565409
|
2-[3-(4-phenylpiperazin-1-yl)propoxy]benzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0853338
|
1-[3-(Mesityloxy)propyl]-4-(4-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
Ki = 146 nM
|
|
|
|
CP0396072
|
5-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 146 nM
|
|
|
|
CP0443917
|
2-(5-methoxy-1H-indol-3-yl)-N-[[5-(1H-pyrazol-4-yl)furan-2-yl]methyl]ethanamine
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
Ki = 146 nM
|
|
|
|
CP0433627
|
5-chloro-N-[(3S)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C22H23ClN2O3S2
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0377051
|
N-[(1S)-1-(4-cyanophenyl)ethyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H38N4O2
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0390939
|
6-fluoro-3-[1-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0396618
|
4-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0447114
|
3-chloro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C26H27ClN2O2
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0376749
|
N-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C36H48N4O3
|
1
|
| 1 |
Ki = 149 nM
|
|
|
|
CP0483144
|
3-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
|
1
|
| 1 |
Ki = 149 nM
|
|
|
|
CP0565302
|
4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(4-propan-2-ylphenyl)butanamide;hydrochloride
Show/Hide
|
C24H34ClN3O2
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0147561
|
5-(Dimethylamino)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-naphthalenesulfonamide
Show/Hide
|
C27H36N4O3S
|
1
|
| 1 |
Ki = 151 nM
|
|
|
|
CP0376750
|
N-[[4-(2-hydroxyethoxy)phenyl]methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H41N3O4
|
1
|
| 1 |
Ki = 152 nM
|
|
|
|
CP0569512
|
2-[2-[4-(3-methoxyphenyl)piperazin-1-yl]ethoxy]benzamide
Show/Hide
|
C20H25N3O3
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0469370
|
1,1-dioxo-2-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
Ki = 156 nM
|
|
|
|
CP0435205
|
5-methoxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C19H20N2OS
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0385588
|
N-(cyclopropylmethyl)-3-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H35FN2O3S
|
1
|
| 1 |
Ki = 158 nM
|
|
|
|
CP0111551
|
5-chloro-N-(4-piperazin-1-ylquinolin-6-yl)naphthalene-2-sulfonamide
Show/Hide
|
C23H21ClN4O2S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0850794
|
4-Fluoro-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
|
C25H27FN2O3S
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0403500
|
N-(cyclopropylmethyl)-1-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C27H34N4O3S
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0881044
|
1-[2-(3,4-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0376759
|
N-[[4-(methoxymethoxy)phenyl]methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H41N3O4
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0377049
|
N-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C35H46N4O3
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0424237
|
5-ethoxy-3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0445708
|
N-benzyl-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C29H35N3O
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0416667
|
1-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H30Cl3N3O
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0476102
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]hexanamide
Show/Hide
|
C36H48N4O4
|
1
|
| 1 |
Ki = 163 nM
|
|
|
|
CP0286141
|
6-{4-[2-(propan-2-yl)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C29H41N3O
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0065211
|
6-[4-(2-propylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C29H41N3O
|
1
|
| 1 |
Ki = 168 nM
|
|
|
|
CP0511150
|
4-fluoro-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C27H29FN2O3S
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0541083
|
2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
Ki = 172 nM
|
|
|
|
CP0849206
|
3-Chloro-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-benzenesulfonamide
Show/Hide
|
C22H29ClN2O3S
|
1
|
| 1 |
Ki = 178 nM
|
|
|
|
CP0391298
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 179 nM
|
|
|
|
CP0375465
|
4-fluoro-N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0383840
|
1-(4-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C30H29N3O
|
1
|
| 1 |
Ki = 181 nM
|
|
|
|
CP0483353
|
1-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
|
| 1 |
Ki = 181 nM
|
|
|
|
CP0849205
|
2,5-Difluoro-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
|
C25H26F2N2O3S
|
1
|
| 1 |
Ki = 183 nM
|
|
|
|
CP0411952
|
3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methyl-5-(4-methylphenyl)imidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C25H33ClN4O4
|
1
|
| 1 |
Ki = 184 nM
|
|
|
|
CP0534675
|
4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(3-propan-2-ylphenyl)butanamide;hydrochloride
Show/Hide
|
C24H34ClN3O2
|
1
|
| 1 |
Ki = 187 nM
|
|
|
|
CP0070944
|
N-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H34N4O
|
1
|
| 1 |
Ki = 188 nM
|
|
|
|
CP0385646
|
5-chloro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]thiophene-2-sulfonamide
Show/Hide
|
C23H25ClN2O3S2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0420682
|
3-fluoro-N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0483154
|
1-(4-fluorophenyl)-3-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]urea
Show/Hide
|
C23H30FN3O2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0477980
|
3-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C25H33ClN4O4
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0530412
|
CHEMBL4756826
Show/Hide
|
C23H33ClN2O
|
1
|
| 1 |
Ki = 191.4 nM
|
|
|
|
CP0286140
|
1-oxido-2-{4-[5-(1,2,3,4-tetrahydronaphthalen-1-ylcarbamoyl)pentyl]piperazin-1-yl}pyridin-1-ium
Show/Hide
|
C25H34N4O2
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0435206
|
5-ethoxy-3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0508131
|
3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-5-methoxy-1H-indole
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 195 nM
|
|
|
|
CP0472948
|
4-fluoro-N-[1-[2-(2-propan-2-yloxyphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H29FN2O4S
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0480662
|
3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5,5-diphenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C29H33ClN4O4
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0495706
|
3-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0546050
|
2-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]pyrazine
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0472949
|
4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C23H29FN2O2
|
1
|
| 1 |
Ki = 199 nM
|
|
|
|
CP0165719
|
N-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0528511
|
4-fluoro-5-methoxy-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12FN3O
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0553509
|
2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-isoindole-1,3-dione
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0489716
|
3-benzyl-1-[5-[4-(4-fluorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H35FN4O2
|
1
|
| 1 |
Ki = 201 nM
|
|
|
|
CP0476100
|
N-benzyl-6-[(2S)-2-methyl-4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 202 nM
|
|
|
|
CP0466465
|
4-[5-[[2-(6-fluoro-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C21H19FN2O2
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1
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| 1 |
Ki = 202 nM
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CP0435201
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3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-5-propan-2-yloxy-1H-indole
Show/Hide
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C23H26N2O
|
1
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| 1 |
Ki = 203 nM
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CP0502989
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1-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-phenylpyridazine-3,6-dione
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C23H25ClN4O2
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1
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| 1 |
Ki = 204.17 nM
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CP0487916
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3-chloro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
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C24H31ClN2O3S
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1
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| 1 |
Ki = 206 nM
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CP0545007
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3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-2-thione
Show/Hide
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C26H33ClN4S
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1
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| 1 |
Ki = 206 nM
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CP0419312
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(1S)-17-methoxy-5,8-dioxa-14-azapentacyclo[12.8.0.02,11.04,9.016,21]docosa-2,4(9),10,16(21),17,19-hexaen-18-ol
Show/Hide
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C20H21NO4
|
1
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| 1 |
Ki = 208 nM
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CP0860096
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2,5-Difluoro-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-benzenesulfonamide
Show/Hide
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C22H28F2N2O3S
|
1
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| 1 |
Ki = 208 nM
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CP0911543
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1-[2-(2-Methoxy-4-methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
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C18H23ClN2OS
|
1
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| 1 |
Ki = 210 nM
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CP0411735
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(3S)-2-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C25H31ClN4O2
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1
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| 1 |
Ki = 211 nM
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CP0382296
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(3S)-2-[4-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]benzoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C28H28Cl2N4O2
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1
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| 1 |
Ki = 212 nM
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CP0434816
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(2S)-1-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C21H32N4O3
|
1
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| 1 |
Ki = 214 nM
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CP0542063
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(2S)-1-[6-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C22H31N5O3
|
1
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| 1 |
Ki = 214 nM
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CP0429858
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N-(cyclopropylmethyl)-1-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
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C24H36N4O3S
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1
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| 1 |
Ki = 214 nM
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CP0435200
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5-propan-2-yloxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
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C21H24N2OS
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1
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| 1 |
Ki = 214 nM
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CP0443914
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N-[[5-(4-chlorophenyl)furan-2-yl]methyl]-2-(5-methoxy-1H-indol-3-yl)ethanamine
Show/Hide
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C22H21ClN2O2
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1
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| 1 |
Ki = 218 nM
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CP0383842
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1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-dihydro-2Hindol-2-one
Show/Hide
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C21H24N2O
|
1
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| 1 |
Ki = 219 nM
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CP0477977
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2-[4-[2-hydroxy-3-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]propyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
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C25H30ClN5O4
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1
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| 1 |
Ki = 219 nM
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CP0435203
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3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-5-ethoxy-1H-indole
Show/Hide
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C22H24N2O
|
1
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| 1 |
Ki = 220 nM
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CP0757055
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3-(1-methyl-1H-imidazol-5-yl)-1H-indole-5-carboxamide
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C13H12N4O
|
1
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| 1 |
Ki = 220 nM
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CP0486488
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N-(3-tert-butylphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
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C25H36ClN3O2
|
1
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| 1 |
Ki = 224 nM
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CP0484847
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3,4-difluoro-N-[1-[2-(3-fluorophenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C18H19F3N2O3S
|
1
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| 1 |
Ki = 230 nM
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CP0513136
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(3S)-2-[6-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C27H33N5O3
|
1
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| 1 |
Ki = 230 nM
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CP0416176
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(2S)-1-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
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C21H31ClN4O2
|
1
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| 1 |
Ki = 232 nM
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CP0850796
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5-N-(1-{2-[(Propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-quinolinesulfonamide
Show/Hide
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C25H31N3O3S
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1
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| 1 |
Ki = 232 nM
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CP0849204
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3-Chloro-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
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C25H27ClN2O3S
|
1
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| 1 |
Ki = 234 nM
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CP0497329
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3-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]quinazolin-4-one
Show/Hide
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C21H23ClN4O
|
1
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| 1 |
Ki = 234.42 nM
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CP0510463
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3-benzyl-1-[5-[4-(2,4-difluorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
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C27H34F2N4O2
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1
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| 1 |
Ki = 235 nM
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CP0469504
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(3S)-2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C26H33ClN4O2
|
1
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| 1 |
Ki = 236 nM
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CP0381350
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N-[1-(2-phenoxyethyl)piperidin-4-yl]thiophene-2-sulfonamide
Show/Hide
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C17H22N2O3S2
|
1
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| 1 |
Ki = 237 nM
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CP0852399
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1-[2-(4-Trifluoromethyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
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C17H18ClF3N2S
|
1
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| 1 |
Ki = 240 nM
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CP0424239
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3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
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C21H22N2O
|
1
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| 1 |
Ki = 243 nM
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CP0424242
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3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
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C21H22N2O
|
1
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| 1 |
Ki = 243 nM
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CP0846357
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N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-benzenesulfonamide
Show/Hide
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C22H30N2O3S
|
1
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| 1 |
Ki = 249 nM
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CP0385589
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N-(cyclopropylmethyl)-4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H35FN2O3S
|
1
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| 1 |
Ki = 249 nM
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CP0061062
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6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethyl}-pyrrolidine-1-sulfonyl)-1H-indole; hydrochloride
Show/Hide
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C25H30ClN3O3S
|
2
|
| 1 |
Ki = 250 nM
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| 2 |
Ki = 562.34 nM
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CP0185590
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4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
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C18H22BrN3O3S
|
1
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| 1 |
Ki = 251.19 nM
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CP0208303
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5-chloro-2-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-3-sulfonamide
Show/Hide
|
C22H21ClN4O2S2
|
1
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| 1 |
Ki = 251.19 nM
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CP0407076
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3-chloro-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
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C27H29ClN2O3S
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1
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| 1 |
Ki = 254 nM
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CP0417576
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5-[4-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C26H30Cl2N4O2S
|
1
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| 1 |
Ki = 257 nM
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CP0555809
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2-(4-fluorophenyl)sulfonyl-5-[2-(2-propan-2-ylphenoxy)ethyl]-2,5-diazabicyclo[2.2.1]heptane
Show/Hide
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C22H27FN2O3S
|
1
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| 1 |
Ki = 260 nM
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CP0528509
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3-(3-ethylimidazol-4-yl)-4-fluoro-5-methoxy-1H-indole
Show/Hide
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C14H14FN3O
|
1
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| 1 |
Ki = 263 nM
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CP0546048
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2-[5-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3,3-dimethylpentoxy]pyrazine
Show/Hide
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C28H36N4O2
|
1
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| 1 |
Ki = 264 nM
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CP0572596
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(2R)-1-(4-chloro-2-fluorophenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propan-2-ol
Show/Hide
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C26H28ClFN2O3
|
1
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| 1 |
Ki = 264 nM
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CP0453915
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N-[1-[2-(3-fluorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
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C16H19FN2O3S2
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1
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| 1 |
Ki = 270 nM
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CP0963763
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2-Methylpropane-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-sulfonamide
Show/Hide
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C20H34N2O3S
|
1
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| 1 |
Ki = 278 nM
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CP0947175
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N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
|
C25H28N2O3S
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1
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| 1 |
Ki = 279 nM
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CP0455245
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3-chloro-N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
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C20H24ClFN2O3S
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1
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| 1 |
Ki = 283 nM
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CP0537958
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(2R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperidin-1-yl]-3-pyrazin-2-yloxypropan-2-ol
Show/Hide
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C25H29N3O3
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1
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| 1 |
Ki = 287 nM
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CP0512458
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tert-butyl 4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butanoylamino]benzoate;hydrochloride
Show/Hide
|
C26H36ClN3O4
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1
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| 1 |
Ki = 287 nM
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CP0484860
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4-fluoro-N-[[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H29FN2O3S
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1
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| 1 |
Ki = 290 nM
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CP0558519
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3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-5-propan-2-yloxy-1H-indole
Show/Hide
|
C24H28N2O2
|
1
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| 1 |
Ki = 290 nM
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CP0384571
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1-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H33N3O2
|
1
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| 1 |
Ki = 291 nM
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CP0457522
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4-[5-[[2-(1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C21H20N2O2
|
1
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| 1 |
Ki = 292 nM
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CP0512459
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N-[(2-methoxyphenyl)methyl]-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
|
C23H32ClN3O3
|
1
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| 1 |
Ki = 292 nM
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CP0513126
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1-[5-[4-(2,4-difluorophenyl)piperazin-1-yl]pentyl]-3-[(4-fluorophenyl)methyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H33F3N4O2
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1
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| 1 |
Ki = 299 nM
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CP0382802
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3-[(2,4-dichlorophenyl)methyl]-1-[5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H32Cl4N4O2
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1
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| 1 |
Ki = 301 nM
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CP0510465
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3-[(4-fluorophenyl)methyl]-1-[5-[4-(4-fluorophenyl)piperazin-1-yl]pentyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H34F2N4O2
|
1
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| 1 |
Ki = 305 nM
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CP0476109
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2-[4-[3-[4-(4-chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C24H27Cl2N5O3
|
1
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| 1 |
Ki = 305 nM
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CP0424241
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3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C18H18N2S
|
1
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| 1 |
Ki = 305 nM
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CP0930877
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1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-[1,4]diazepane Hydrochloride
Show/Hide
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C19H25ClN2S
|
1
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| 1 |
Ki = 310 nM
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CP0381352
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3,4-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C25H26F2N2O3S
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1
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| 1 |
Ki = 313 nM
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CP0513134
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(2S)-1-[4-[[4-(2-methylsulfanylphenyl)piperazin-1-yl]methyl]benzoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
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| 1 |
Ki = 313 nM
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CP0421834
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5-bromo-3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
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C13H11BrFN3
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1
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| 1 |
Ki = 316 nM
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CP0271460
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(R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
|
C18H26Cl2N2O2S
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1
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| 1 |
Ki = 316.23 nM
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CP0434556
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2-[4-[3-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C24H26FN5O3
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1
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| 1 |
Ki = 319 nM
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CP0861986
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1-Methyl-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-1H-pyrazole-4-sulfonamide
Show/Hide
|
C23H28N4O3S
|
1
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| 1 |
Ki = 321 nM
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CP0382070
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1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propyl]-3-methyl-5,5-diphenylimidazolidine-2,4-dione
Show/Hide
|
C29H32N4O3
|
1
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| 1 |
Ki = 324 nM
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CP0448742
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4-[4-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
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| 1 |
Ki = 324 nM
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CP0481424
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4-[2-(1-Methylethyl)phenyl]-N-(4-pyridinylmethyl)-1-piperazinehexanamide
Show/Hide
|
C25H36N4O
|
1
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| 1 |
Ki = 325 nM
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CP0945583
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3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H32N4O4
|
1
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| 1 |
Ki = 326 nM
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CP0554601
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2-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H31N3O4S
|
1
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| 1 |
Ki = 327 nM
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CP0904235
|
1-[2-(2,4-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
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| 1 |
Ki = 330 nM
|
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CP0421349
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2-(5-methoxy-1H-indol-3-yl)-N-[[5-(4-methoxyphenyl)furan-2-yl]methyl]ethanamine
Show/Hide
|
C23H24N2O3
|
1
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| 1 |
Ki = 334 nM
|
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CP0425220
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N-[(2-hydroxyphenyl)methyl]-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
|
C22H30ClN3O3
|
1
|
| 1 |
Ki = 339 nM
|
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CP0412016
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2-[4-[3-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C29H30ClN5O3
|
1
|
| 1 |
Ki = 341 nM
|
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CP0403510
|
N-(cyclopropylmethyl)-4-fluoro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C29H33FN2O3S
|
1
|
| 1 |
Ki = 342 nM
|
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CP0375463
|
N,1-dimethyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C21H32N4O3S
|
1
|
| 1 |
Ki = 346 nM
|
|
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CP0300421
|
3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-1H-indole
Show/Hide
|
C20H20N2
|
1
|
| 1 |
Ki = 354 nM
|
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|
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CP0107214
|
3-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H29FN2O3S
|
1
|
| 1 |
Ki = 356 nM
|
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CP0371906
|
2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 360 nM
|
|
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CP0470858
|
3-[2-[4-(3-phenylpyridin-2-yl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
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C28H31F3N4O2
|
1
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| 1 |
Ki = 365 nM
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CP0904397
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3-Fluoro-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
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C25H27FN2O3S
|
1
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| 1 |
Ki = 368 nM
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CP0448724
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4-[4-[2-[4-(3-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
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C26H31FN4O2S
|
1
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| 1 |
Ki = 370 nM
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CP0563418
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N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]pyridine-3-sulfonamide
Show/Hide
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C21H29N3O3S
|
1
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| 1 |
Ki = 371 nM
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CP0904396
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3,4-Difluoro-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-benzenesulfonamide
Show/Hide
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C22H28F2N2O3S
|
1
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| 1 |
Ki = 373 nM
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CP0511149
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N-[1-[2-(2-cyclopentylphenoxy)ethyl]piperidin-4-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C24H31FN2O3S
|
1
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| 1 |
Ki = 373 nM
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CP0495705
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2-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C28H30N4O4
|
1
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| 1 |
Ki = 373 nM
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CP0469505
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(3S)-2-[5-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
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C26H31N5O3
|
1
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| 1 |
Ki = 377 nM
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CP0535812
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3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-5-propan-2-yloxy-1H-indole
Show/Hide
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C24H28N2O2
|
1
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| 1 |
Ki = 378 nM
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CP0414140
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N-[1-[2-(3-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
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C22H30N2O3S
|
1
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| 1 |
Ki = 388 nM
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CP0466922
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2-(3-chlorophenyl)sulfonyl-5-[2-(2-propan-2-ylphenoxy)ethyl]-2,5-diazabicyclo[2.2.1]heptane
Show/Hide
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C22H27ClN2O3S
|
1
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| 1 |
Ki = 393 nM
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CP0381931
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3-[3-[4-(2-chlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
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C23H26ClFN4O3
|
1
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| 1 |
Ki = 397 nM
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CP0674190
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5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-methoxy-3-piperazin-1-yl-phenyl)-amide hydrochloride
Show/Hide
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C20H23Cl2N3O3S2
|
1
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| 1 |
Ki = 398.11 nM
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CP0051242
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(R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
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C18H27BrN2O2S
|
1
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| 1 |
Ki = 398.11 nM
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CP0041243
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5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
Show/Hide
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C20H22ClN3O3S2
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1
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| 1 |
Ki = 398.11 nM
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CP0430964
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2-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3-phenylphthalazine-1,4-dione
Show/Hide
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C28H29ClN4O2
|
1
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| 1 |
Ki = 398.11 nM
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CP0426434
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4-[5-[[2-(5-methyl-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C22H22N2O2
|
1
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| 1 |
Ki = 399 nM
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CP0561688
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1,1-dioxo-2-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]-1,2-benzothiazol-3-one
Show/Hide
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C21H22F3N3O3S
|
1
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| 1 |
Ki = 400 nM
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CP0572402
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3-[3-(4-phenylpiperazin-1-yl)propyl]-1,3-benzoxazine-2,4-dione
Show/Hide
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C21H23N3O3
|
1
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| 1 |
Ki = 402 nM
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CP0569052
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2-[(2R)-2-hydroxy-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propoxy]benzonitrile
Show/Hide
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C27H29N3O3
|
1
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| 1 |
Ki = 403 nM
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CP0550811
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N-(2-hydroxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
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C21H28ClN3O3
|
1
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| 1 |
Ki = 405 nM
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CP0568683
|
4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C25H31N9
|
1
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| 1 |
Ki = 405 nM
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CP0447118
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4-amino-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
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C25H29N3O3S
|
1
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| 1 |
Ki = 407 nM
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CP0321515
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6-[4-(2-aminophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
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C26H36N4O
|
1
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| 1 |
Ki = 415 nM
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CP0491475
|
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-3-phenylphthalazine-1,4-dione
Show/Hide
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C27H27ClN4O2
|
1
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| 1 |
Ki = 416.87 nM
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CP0866034
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-6-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
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C19H25ClN2S
|
1
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| 1 |
Ki = 420 nM
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CP0426410
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3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H31ClN4O4
|
1
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| 1 |
Ki = 421 nM
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CP0442148
|
N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]propanamide
Show/Hide
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C24H34N4O3S
|
1
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| 1 |
Ki = 426 nM
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CP0876491
|
6-Methoxy-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-9H-xanthen-9-one hydrochloride
Show/Hide
|
C26H27ClN2O4
|
1
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| 1 |
Ki = 429 nM
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CP0534331
|
1-methyl-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]pyrazole-4-sulfonamide
Show/Hide
|
C22H32N4O3S
|
1
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| 1 |
Ki = 431 nM
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CP0478896
|
4-[5-[[2-(5-chloro-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C21H19ClN2O2
|
1
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| 1 |
Ki = 431 nM
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CP0491789
|
3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-5-propan-2-yloxy-1H-indole
Show/Hide
|
C21H24N2O2
|
1
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| 1 |
Ki = 431 nM
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CP0486999
|
4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H29FN2O3S
|
1
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| 1 |
Ki = 436 nM
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CP0507070
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N-[(4-cyanophenyl)methyl]-3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C29H32N4O2
|
1
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| 1 |
Ki = 437 nM
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CP0537956
|
(2R)-1-(4-chloro-3-fluorophenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propan-2-ol
Show/Hide
|
C26H28ClFN2O3
|
1
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| 1 |
Ki = 449 nM
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CP0850793
|
5-Chloro-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-thiophene-2-sulfonamide
Show/Hide
|
C20H27ClN2O3S2
|
1
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| 1 |
Ki = 455 nM
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CP0433626
|
2-ethoxy-N-[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C22H27FN2O3
|
1
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| 1 |
Ki = 456 nM
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CP0513628
|
2-bromo-N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H22Br2N2O3S
|
1
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| 1 |
Ki = 462 nM
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CP0555810
|
4-fluoro-N-[1-[2-(2-methoxyphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H25FN2O4S
|
1
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| 1 |
Ki = 463 nM
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CP0545011
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2-[[4-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H24ClN5O
|
1
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| 1 |
Ki = 467 nM
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CP0563078
|
8-chloro-6-[(2R)-2-hydroxy-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C30H31ClN2O5
|
1
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| 1 |
Ki = 475 nM
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CP0569053
|
2-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]benzonitrile
Show/Hide
|
C28H31N3O2
|
1
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| 1 |
Ki = 477 nM
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CP0417091
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3-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C26H30N4O4S
|
1
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| 1 |
Ki = 482 nM
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CP0424238
|
5-ethoxy-3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C20H22N2O2
|
1
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| 1 |
Ki = 486 nM
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CP0853987
|
3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C19H28N4O4
|
1
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| 1 |
Ki = 489 nM
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CP0469655
|
2-iodo-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23IN2O3S
|
1
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| 1 |
Ki = 496 nM
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CP0411734
|
(3S)-2-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C26H33ClN4O2
|
1
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| 1 |
Ki = 499 nM
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CP0113176
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Show/Hide
|
C21H24ClN3O3S2
|
1
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| 1 |
Ki = 501.19 nM
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CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
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C38H47F6N3O5
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1
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| 1 |
Ki = 501.19 nM
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CP0541050
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4-amino-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H31N3O3S
|
1
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| 1 |
Ki = 502 nM
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CP0520754
|
N-[1-[2-(3-iodophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23IN2O3S
|
1
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| 1 |
Ki = 509 nM
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CP0311351
|
2-[4-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]phenyl]imidazo[1,2-a]pyridine
Show/Hide
|
C34H36N4O2
|
1
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| 1 |
Ki = 521 nM
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CP0549463
|
2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butanoylamino]benzamide;hydrochloride
Show/Hide
|
C22H29ClN4O3
|
1
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| 1 |
Ki = 526 nM
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CP0447119
|
N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]pyridine-3-sulfonamide
Show/Hide
|
C24H27N3O3S
|
1
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| 1 |
Ki = 536 nM
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CP0417078
|
1-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
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| 1 |
Ki = 536 nM
|
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CP0512456
|
N-(5-tert-butyl-2-hydroxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
|
C25H36ClN3O3
|
1
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| 1 |
Ki = 539 nM
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CP0870587
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-3-methyl-phenyl]-piperazine
Show/Hide
|
C19H25ClN2S
|
1
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| 1 |
Ki = 540 nM
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CP0460397
|
4-[4-[2-(4-phenylpiperazin-1-yl)ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H32N4O2S
|
1
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| 1 |
Ki = 543 nM
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CP0413781
|
N-[1-[2-(2-cyclopentylphenoxy)ethyl]piperidin-4-yl]-3-fluorobenzenesulfonamide
Show/Hide
|
C24H31FN2O3S
|
1
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| 1 |
Ki = 545 nM
|
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CP0902025
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C25H38Cl2N2O2
|
1
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| 1 |
Ki = 552 nM
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CP0495732
|
3-chloro-N-[1-[2-(2-cyclopentylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C24H31ClN2O3S
|
1
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| 1 |
Ki = 556 nM
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CP0513137
|
(2S)-1-[6-[4-(4-fluorophenyl)piperazin-1-yl]hexanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C21H31FN4O2
|
1
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| 1 |
Ki = 573 nM
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CP0376742
|
3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C29H32F3N3O2
|
1
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| 1 |
Ki = 582 nM
|
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CP0476108
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2-[4-[2-hydroxy-3-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)propyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C24H28ClN5O3
|
1
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| 1 |
Ki = 585 nM
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CP0344919
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3-(3-ethylimidazol-4-yl)-4-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
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| 1 |
Ki = 589 nM
|
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CP0425219
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N-(4-tert-butylphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide;hydrochloride
Show/Hide
|
C25H36ClN3O2
|
1
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| 1 |
Ki = 590 nM
|
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CP0447117
|
1-(3-chlorophenyl)-3-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]urea
Show/Hide
|
C23H30ClN3O2
|
1
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| 1 |
Ki = 591 nM
|
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CP0376747
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-(3-phenylpyridin-2-yl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
Ki = 595 nM
|
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CP0417075
|
1-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 599 nM
|
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CP0417574
|
5-[4-[2-[4-(3-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
Ki = 609 nM
|
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CP0853601
|
1-Methyl-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-1H-pyrazole-4-sulfonamide
Show/Hide
|
C20H30N4O3S
|
1
|
| 1 |
Ki = 616 nM
|
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CP0469653
|
N-[1-[2-(2-iodophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23IN2O3S
|
1
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| 1 |
Ki = 619 nM
|
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CP0339112
|
4-phenyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
|
C25H24N4O2S
|
1
|
| 1 |
Ki = 630.96 nM
|
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CP0216543
|
N-[3-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H28ClN3O3S2
|
1
|
| 1 |
Ki = 630.96 nM
|
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CP0434535
|
(3S)-2-[6-[4-(4-fluorophenyl)piperazin-1-yl]hexanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C26H33FN4O2
|
1
|
| 1 |
Ki = 643 nM
|
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CP0528508
|
3-(3-ethylimidazol-4-yl)-5-methoxy-1H-indole
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
Ki = 661 nM
|
|
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CP0421837
|
3-(3-ethylimidazol-4-yl)-7-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
|
| 1 |
Ki = 676 nM
|
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CP0301336
|
N-[[4-[5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]pentoxy]phenyl]methyl]-N-methylprop-2-yn-1-amine
Show/Hide
|
C34H40N4O3S
|
1
|
| 1 |
Ki = 684 nM
|
|
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CP0416670
|
1-[6-[4-(4-bromophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31BrClN3O
|
1
|
| 1 |
Ki = 688 nM
|
|
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CP0544200
|
4-N-[2-(2,3-dichlorophenyl)ethyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7
|
1
|
| 1 |
Ki = 706 nM
|
|
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CP0426092
|
5-chloro-N-[1-[2-(2,5-dichlorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H17Cl3N2O3S2
|
1
|
| 1 |
Ki = 717 nM
|
|
|
|
CP0447113
|
1-(3-chlorophenyl)-3-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]urea
Show/Hide
|
C26H28ClN3O2
|
1
|
| 1 |
Ki = 718 nM
|
|
|
|
CP0416657
|
[(13aS)-2,3,9,11-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-12-yl]methanol
Show/Hide
|
C22H27NO5
|
1
|
| 1 |
Ki = 730.02 nM
|
|
|
|
CP0421348
|
4-[5-[[2-(4-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
Ki = 732 nM
|
|
|
|
CP0448726
|
5-[4-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31ClN4O2S
|
1
|
| 1 |
Ki = 740 nM
|
|
|
|
CP0447112
|
4-fluoro-N-[1-[2-(2-methylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H25FN2O3S
|
1
|
| 1 |
Ki = 745 nM
|
|
|
|
CP0470500
|
5-[4-[2-(4-phenylpiperazin-1-yl)ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H32N4O2S
|
1
|
| 1 |
Ki = 749 nM
|
|
|
|
CP0424236
|
3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
Ki = 752 nM
|
|
|
|
CP0417573
|
5-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
Ki = 759 nM
|
|
|
|
CP0414194
|
3-bromo-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0046432
|
N-[(4-cyanophenyl)methyl]-6-[4-[4-fluoro-2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C31H35FN4O2
|
1
|
| 1 |
Ki = 771 nM
|
|
|
|
CP0443918
|
2-(1H-indol-3-yl)-N-methyl-N-[(5-phenylfuran-2-yl)methyl]ethanamine
Show/Hide
|
C22H22N2O
|
1
|
| 1 |
Ki = 775 nM
|
|
|
|
CP0081712
|
4-tert-butyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0082421
|
5-chloro-3-methyl-N-(2-methyl-4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0306083
|
5-chloro-3-methyl-N-[4-(4-methylpiperazin-1-yl)quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0853819
|
(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0525594
|
3-[2-[4-(2-phenylpyridin-3-yl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H31F3N4O2
|
1
|
| 1 |
Ki = 802 nM
|
|
|
|
CP0551133
|
2-[4-[4-[2-(4-methoxyphenyl)phenyl]piperidin-1-yl]butoxy]pyrazine
Show/Hide
|
C26H31N3O2
|
1
|
| 1 |
Ki = 811 nM
|
|
|
|
CP0397958
|
3-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H25Cl2FN4O3
|
1
|
| 1 |
Ki = 821 nM
|
|
|
|
CP0440392
|
5-iodo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H10IN3
|
1
|
| 1 |
Ki = 832 nM
|
|
|
|
CP0481686
|
N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]thiophene-2-sulfonamide
Show/Hide
|
C18H23FN2O3S2
|
1
|
| 1 |
Ki = 841 nM
|
|
|
|
CP0484861
|
4-fluoro-N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C20H24F2N2O3S
|
1
|
| 1 |
Ki = 903 nM
|
|
|
|
CP0421836
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole-5-carboxamide
Show/Hide
|
C14H13FN4O
|
1
|
| 1 |
Ki = 933 nM
|
|
|
|
CP0541027
|
1-methyl-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]pyrazole-4-sulfonamide
Show/Hide
|
C25H30N4O3S
|
1
|
| 1 |
Ki = 947 nM
|
|
|
|
CP0537957
|
1-[4-(4-chloro-2-fluorophenoxy)butyl]-4-[2-(4-methoxyphenyl)phenyl]piperazine
Show/Hide
|
C27H30ClFN2O2
|
1
|
| 1 |
Ki = 967 nM
|
|
|
|
CP0448725
|
4-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
Ki = 975 nM
|
|
|
|
CP0417076
|
3-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 989 nM
|
|
|
|
CP0182705
|
(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)
Show/Hide
|
C19H30N2O2S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0198069
|
(R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)
Show/Hide
|
C22H30N2O2S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0173778
|
5-chloro-3-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H21ClN4O2S2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0343547
|
5-chloro-3-methyl-N-[4-[(3S)-3-methylpiperazin-1-yl]quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0434555
|
3-[3-[4-(3,4-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C25H31FN4O3
|
1
|
| 1 |
Ki = 1004 nM
|
|
|
|
CP0249646
|
4-[5-[[2-(5-fluoro-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C21H19FN2O2
|
1
|
| 1 |
Ki = 1010 nM
|
|
|
|
CP0413064
|
3-(3-ethylimidazol-4-yl)-5-iodo-1H-indole
Show/Hide
|
C13H12IN3
|
2
|
| 1 |
Ki = 1047 nM
|
|
|
| 2 |
Ki = 1053 nM
|
|
|
|
CP0478897
|
2-(5-methoxy-1H-indol-3-yl)-N-[(5-quinolin-3-ylfuran-2-yl)methyl]ethanamine
Show/Hide
|
C25H23N3O2
|
1
|
| 1 |
Ki = 1052 nM
|
|
|
|
CP0382644
|
3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]-N-(pyridin-4-ylmethyl)propanamide
Show/Hide
|
C27H32N4O2
|
1
|
| 1 |
Ki = 1055 nM
|
|
|
|
CP0487915
|
2-(4-fluorophenyl)sulfonyl-5-[2-(2-phenylphenoxy)ethyl]-2,5-diazabicyclo[2.2.1]heptane
Show/Hide
|
C25H25FN2O3S
|
1
|
| 1 |
Ki = 1068 nM
|
|
|
|
CP0528449
|
5-bromo-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9BrFN3
|
1
|
| 1 |
Ki = 1072 nM
|
|
|
|
CP0456107
|
1'-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 1096 nM
|
|
|
|
CP0852396
|
1-[2-(4-Fluoro-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H20ClFN2S
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0852397
|
1-(5-Methyl-2-phenylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0864861
|
3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
Ki = 1155 nM
|
|
|
|
CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
|
| 1 |
Ki = 1169 nM
|
|
|
|
CP0575067
|
2-N-[2-(2,3-dichlorophenoxy)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7O
|
1
|
| 1 |
Ki = 1188 nM
|
|
|
|
CP0333597
|
6-[4-(2-tert-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C30H43N3O
|
1
|
| 1 |
Ki = 1196 nM
|
|
|
|
CP0874391
|
3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H29N5O3
|
1
|
| 1 |
Ki = 1225 nM
|
|
|
|
CP0421835
|
5-bromo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H10BrN3
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0440391
|
5-bromo-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12BrN3
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0525726
|
3-bromo-N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H22Br2N2O3S
|
1
|
| 1 |
Ki = 1266 nM
|
|
|
|
CP0511767
|
(2R)-1-(4-imidazo[1,2-a]pyridin-2-ylphenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propan-2-ol
Show/Hide
|
C33H34N4O3
|
1
|
| 1 |
Ki = 1270 nM
|
|
|
|
CP0518072
|
N-[1-[2-(2-chlorophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
Ki = 1285 nM
|
|
|
|
CP0404556
|
3-[3-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C25H31FN4O3
|
1
|
| 1 |
Ki = 1304 nM
|
|
|
|
CP0417452
|
3-[(3-chlorophenyl)methyl]-2-ethyl-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22ClN5
|
1
|
| 1 |
Ki = 1354 nM
|
|
|
|
CP0500596
|
2,2-dimethyl-N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]propanamide
Show/Hide
|
C26H38N4O3S
|
1
|
| 1 |
Ki = 1360 nM
|
|
|
|
CP0552306
|
2-[4-[4-[4-[2-(4-methoxyphenyl)phenyl]piperidin-1-yl]butoxy]phenyl]imidazo[1,2-a]pyridine
Show/Hide
|
C35H37N3O2
|
1
|
| 1 |
Ki = 1370 nM
|
|
|
|
CP0895089
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-4-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0402394
|
N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]-3-chlorobenzenesulfonamide
Show/Hide
|
C19H22BrClN2O3S
|
1
|
| 1 |
Ki = 1411 nM
|
|
|
|
CP0469654
|
3-chloro-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
Ki = 1428 nM
|
|
|
|
CP0525728
|
N-[1-[2-(3-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
Ki = 1456 nM
|
|
|
|
CP0518057
|
N-[1-[2-(3-tert-butylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H32N2O3S
|
1
|
| 1 |
Ki = 1545 nM
|
|
|
|
CP0900155
|
5-(4-Fluorophenyl)-3-[2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C22H24FN3O3
|
1
|
| 1 |
Ki = 1551 nM
|
|
|
|
CP0712961
|
(R)-sulfonamide1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
|
C23H32N2O2S
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0382742
|
4-[(2,4-dichlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H18Cl2N6O
|
1
|
| 1 |
Ki = 1610 nM
|
|
|
|
CP0402393
|
N-[1-[2-(3-chlorophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
Ki = 1637 nM
|
|
|
|
CP0462367
|
5-(4-fluorophenyl)-3-[3-[4-(2-fluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H26F2N4O3
|
1
|
| 1 |
Ki = 1646 nM
|
|
|
|
CP0846085
|
6-methoxy-2-{[4-(benzyl)piperazin-1-yl]methyl}-9H-xanthen-9-one dihydrochloride
Show/Hide
|
C26H28Cl2N2O3
|
1
|
| 1 |
Ki = 1671 nM
|
|
|
|
CP0438623
|
4-[(2-chlorophenyl)sulfanylmethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6S
|
1
|
| 1 |
Ki = 1680 nM
|
|
|
|
CP0528510
|
5-chloro-3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki = 1698 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
1
|
| 1 |
Ki = 1703 nM
|
|
|
|
CP0537948
|
4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C13H11FN4O
|
1
|
| 1 |
Ki = 1738 nM
|
|
|
|
CP0541026
|
4-fluoro-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23FN2O3S
|
1
|
| 1 |
Ki = 1764 nM
|
|
|
|
CP0377050
|
3-[2-[4-[3-(4-fluorophenyl)pyridin-2-yl]piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H30F4N4O2
|
1
|
| 1 |
Ki = 1836 nM
|
|
|
|
CP0495733
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-3-chlorobenzenesulfonamide
Show/Hide
|
C23H31ClN2O3S
|
1
|
| 1 |
Ki = 1847 nM
|
|
|
|
CP0391906
|
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14FN3
|
1
|
| 1 |
Ki = 1866 nM
|
|
|
|
CP0530224
|
6-[3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C22H19N3O2S
|
1
|
| 1 |
Ki = 1872 nM
|
|
|
|
CP0416045
|
(3S)-2-[5-[4-(4-fluorophenyl)piperazin-1-yl]pentanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C25H31FN4O2
|
1
|
| 1 |
Ki = 1914 nM
|
|
|
|
CP0525727
|
N-[1-[2-[3-(trifluoromethyl)phenoxy]ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H23F3N2O3S
|
1
|
| 1 |
Ki = 1951 nM
|
|
|
|
CP0383121
|
4-bromo-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
Ki = 1961 nM
|
|
|
|
CP0538843
|
2-chloro-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
Ki = 2058 nM
|
|
|
|
CP0469656
|
2-bromo-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
Ki = 2077 nM
|
|
|
|
CP0411230
|
N-[1-[2-(3-methylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
Ki = 2108 nM
|
|
|
|
CP0440388
|
3-(3-ethylimidazol-4-yl)-5-methyl-1H-indole
Show/Hide
|
C14H15N3
|
1
|
| 1 |
Ki = 2138 nM
|
|
|
|
CP0489717
|
1-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-3-[(2,4-dichlorophenyl)methyl]-5,5-dimethylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C27H33Cl3N4O2
|
1
|
| 1 |
Ki = 2178 nM
|
|
|
|
CP0469657
|
N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
Ki = 2211 nM
|
|
|
|
CP0476107
|
3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-methoxyphenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C31H37ClN4O4
|
1
|
| 1 |
Ki = 2249 nM
|
|
|
|
CP0417454
|
3-[(3-chlorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24ClN5
|
1
|
| 1 |
Ki = 2277 nM
|
|
|
|
CP0421838
|
3-(3-ethylimidazol-4-yl)-5-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki = 2344 nM
|
|
|
|
CP0541120
|
5-chloro-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9ClFN3
|
1
|
| 1 |
Ki = 2344 nM
|
|
|
|
CP0385628
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-methylbenzenesulfonamide
Show/Hide
|
C24H34N2O3S
|
1
|
| 1 |
Ki = 2346 nM
|
|
|
|
CP0518071
|
N-[1-[2-(2-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
Ki = 2349 nM
|
|
|
|
CP0518070
|
N-[1-[2-(2-methylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
Ki = 2368 nM
|
|
|
|
CP0073333
|
3-benzenesulfonyl-8-piperazin-1-ylquinoline
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
Ki = 2370 nM
|
|
|
|
CP0425238
|
1-[4-(4-chloro-3-fluorophenoxy)butyl]-4-[2-(4-methoxyphenyl)phenyl]piperazine
Show/Hide
|
C27H30ClFN2O2
|
1
|
| 1 |
Ki = 2394 nM
|
|
|
|
CP0400394
|
5'-Chloro-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4c)
Show/Hide
|
C24H16ClN3O
|
1
|
| 1 |
Ki = 2450 nM
|
|
|
|
CP0554271
|
7-[5-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C22H18ClN3O2S
|
1
|
| 1 |
Ki = 2467 nM
|
|
|
|
CP0040627
|
6-[4-(2-acetamidophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
|
C28H38N4O2
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0852398
|
1-[2-(4-tert-Butyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C20H27ClN2S
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0882250
|
1-[2-(4-Chloro-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H20Cl2N2S
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0376744
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-[3-(4-fluorophenyl)pyridin-2-yl]piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H30FN5O2
|
1
|
| 1 |
Ki = 2630 nM
|
|
|
|
CP0458453
|
2-(3-chlorophenyl)sulfonyl-5-[2-(2-phenylphenoxy)ethyl]-2,5-diazabicyclo[2.2.1]heptane
Show/Hide
|
C25H25ClN2O3S
|
1
|
| 1 |
Ki = 2667 nM
|
|
|
|
CP0411233
|
4-bromo-N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H22Br2N2O3S
|
1
|
| 1 |
Ki = 2669 nM
|
|
|
|
CP0469659
|
N-[1-[2-(3-bromo-2-iodophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H22BrIN2O3S
|
1
|
| 1 |
Ki = 2677 nM
|
|
|
|
CP0456103
|
1'-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 2687 nM
|
|
|
|
CP0912420
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-5-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
|
CP0472031
|
5-(4-fluorophenyl)-3-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
Ki = 2733 nM
|
|
|
|
CP0379115
|
10-[(4-chloro-2-fluorophenyl)methyl]phenothiazine 5,5-dioxide
Show/Hide
|
C19H13ClFNO2S
|
1
|
| 1 |
Ki = 2745 nM
|
|
|
|
CP0486336
|
(2R)-1-(4-imidazo[1,2-a]pyridin-2-ylphenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperidin-1-yl]propan-2-ol
Show/Hide
|
C34H35N3O3
|
1
|
| 1 |
Ki = 2750 nM
|
|
|
|
CP0073332
|
2-ethyl-3-[(3-fluorophenyl)methyl]-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22FN5
|
1
|
| 1 |
Ki = 2790 nM
|
|
|
|
CP0914964
|
1-(5-Methyl-2-p-tolylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0376748
|
6-[4-[2-(4-cyanophenyl)-4-fluorophenyl]piperazin-1-yl]-N-[(4-cyanophenyl)methyl]hexanamide
Show/Hide
|
C31H32FN5O
|
1
|
| 1 |
Ki = 2870 nM
|
|
|
|
CP0383204
|
1'-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H29ClN4O
|
1
|
| 1 |
Ki = 2891 nM
|
|
|
|
CP0411737
|
(2S)-1-[5-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]pentanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C21H29N5O3
|
1
|
| 1 |
Ki = 2908 nM
|
|
|
|
CP0430227
|
5-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 2944 nM
|
|
|
|
CP0381934
|
5-(4-fluorophenyl)-3-[2-hydroxy-3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
Ki = 2969 nM
|
|
|
|
CP0867162
|
2-(2-{4-[2-(Mesityloxy)ethyl]piperazin-1-yl}ethoxy)ethanol dihydrochloride
Show/Hide
|
C19H34Cl2N2O3
|
1
|
| 1 |
Ki = 3168 nM
|
|
|
|
CP0382740
|
4-(4-methylpiperazin-1-yl)-6-(phenylselanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6Se
|
1
|
| 1 |
Ki = 3176 nM
|
|
|
|
CP0568664
|
4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyphenoxy)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
Ki = 3177 nM
|
|
|
|
CP0538852
|
4-chloro-N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
Ki = 3198 nM
|
|
|
|
CP0541126
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethoxy)-1H-indole
Show/Hide
|
C14H12F3N3O
|
1
|
| 1 |
Ki = 3311 nM
|
|
|
|
CP0402157
|
4-[1-(2-chlorophenyl)sulfanylethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6S
|
1
|
| 1 |
Ki = 3384 nM
|
|
|
|
CP0382746
|
4-[1-(3-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 3438 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
Ki = 3442 nM
|
|
|
|
CP0417063
|
2-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C29H33N3O3
|
1
|
| 1 |
Ki = 3569 nM
|
|
|
|
CP0431612
|
4-[(4-chloro-3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 3584 nM
|
|
|
|
CP0845451
|
1-Dehydro-10-gingerdione
Show/Hide
|
C21H30O4
|
1
|
| 1 |
Ki = 3590 nM
|
|
|
|
CP0518056
|
N-[1-(2-phenoxyethyl)piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H24N2O3S
|
1
|
| 1 |
Ki = 3614 nM
|
|
|
|
CP0323182
|
10-Gingerol
Show/Hide
|
C21H34O4
|
1
|
| 1 |
Ki = 3740 nM
|
|
|
|
CP0456102
|
1'-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 3755 nM
|
|
|
|
CP0384209
|
4-chloro-N-(2-isoquinolin-1-ylphenyl)benzenesulfonamide
Show/Hide
|
C21H15ClN2O2S
|
1
|
| 1 |
Ki = 3842 nM
|
|
|
|
CP0445867
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-(2-phenylpyridin-3-yl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
Ki = 3842 nM
|
|
|
|
CP0217150
|
IDALOPIRDINE
Show/Hide
|
C20H19F5N2O
|
1
|
| 1 |
Ki = 3936 nM
|
|
|
|
CP0456104
|
1'-[2-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H26FN3O
|
1
|
| 1 |
Ki = 3949 nM
|
|
|
|
CP0667134
|
1-[2-(4-Methoxy-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C18H23ClN2OS
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0412404
|
1'-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H26Cl2N4O
|
1
|
| 1 |
Ki = 4054 nM
|
|
|
|
CP0469561
|
N-[1-[2-(3-bromophenoxy)ethyl]piperidin-4-yl]-4-chlorobenzenesulfonamide
Show/Hide
|
C19H22BrClN2O3S
|
1
|
| 1 |
Ki = 4067 nM
|
|
|
|
CP0379113
|
5-bromo-N-[1-(naphthalen-1-ylmethyl)pyrazol-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C18H14BrN3O2S2
|
1
|
| 1 |
Ki = 4307 nM
|
|
|
|
CP0411229
|
N-[1-[2-[2-(trifluoromethyl)phenoxy]ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C20H23F3N2O3S
|
1
|
| 1 |
Ki = 4358 nM
|
|
|
|
CP0530508
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethyl)-1H-indole
Show/Hide
|
C14H12F3N3
|
1
|
| 1 |
Ki = 4365 nM
|
|
|
|
CP0382741
|
4-(4-methylpiperazin-1-yl)-6-(phenylsulfanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6S
|
1
|
| 1 |
Ki = 4389 nM
|
|
|
|
CP0876490
|
3-Chloro-5-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-9H-xanthen-9-one dihydrochloride
Show/Hide
|
C20H24Cl4N2O3
|
1
|
| 1 |
Ki = 4503 nM
|
|
|
|
CP0385587
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-3-fluoro-N-methylbenzenesulfonamide
Show/Hide
|
C24H33FN2O3S
|
1
|
| 1 |
Ki = 4511 nM
|
|
|
|
CP0402156
|
4-[1-(2-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 4540 nM
|
|
|
|
CP0447116
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 4570 nM
|
|
|
|
CP0400005
|
5-chloro-2-(3,4-dihydro-1H-isoquinolin-2-yl)-4-(4-methylphenyl)sulfonyl-1,3-thiazole
Show/Hide
|
C19H17ClN2O2S2
|
1
|
| 1 |
Ki = 4592 nM
|
|
|
|
CP0548225
|
2-(cyclohexen-1-yl)-N-[(3-methoxy-4-phenylmethoxyphenyl)methyl]ethanamine
Show/Hide
|
C23H29NO2
|
1
|
| 1 |
Ki = 4900 nM
|
|
|
|
CP0430226
|
4-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylisoquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 5009 nM
|
|
|
|
CP0430225
|
7-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 5036 nM
|
|
|
|
CP0864860
|
5-(4-Fluorophenyl)-3-[2-hydroxy-3-(4-phenoxypiperidin-1-yl)-propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H28FN3O4
|
1
|
| 1 |
Ki = 5211 nM
|
|
|
|
CP0434552
|
3-[3-[4-(4-chlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H26ClFN4O3
|
1
|
| 1 |
Ki = 5298 nM
|
|
|
|
CP0402058
|
4-(4-methylpiperazin-1-yl)-6-(1-phenylselanylethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6Se
|
1
|
| 1 |
Ki = 5311 nM
|
|
|
|
CP0382744
|
4-[(2-chlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O
|
1
|
| 1 |
Ki = 5467 nM
|
|
|
|
CP0447111
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-1-methylpyrazole-4-sulfonamide
Show/Hide
|
C21H32N4O3S
|
1
|
| 1 |
Ki = 5555 nM
|
|
|
|
CP0122652
|
3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
Ki = 5570 nM
|
|
|
|
CP0900154
|
5-(4-Fluorophenyl)-3-(2-hydroxy-3-{4-[(naphthalen-1-yl)-methyl]piperazin-1-yl}propyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C28H31FN4O3
|
1
|
| 1 |
Ki = 5577 nM
|
|
|
|
CP0562326
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki = 5623 nM
|
|
|
|
CP0845450
|
(10)-Shagaol
Show/Hide
|
C21H32O3
|
1
|
| 1 |
Ki = 5840 nM
|
|
|
|
CP0389653
|
3-[(3-fluorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24FN5
|
1
|
| 1 |
Ki = 5934 nM
|
|
|
|
CP0485159
|
1'-[2-(4-phenylpiperazin-1-yl)ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H28N4O
|
1
|
| 1 |
Ki = 6005 nM
|
|
|
|
CP0376746
|
3-[2-[4-[2-(4-fluorophenyl)pyridin-3-yl]piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H30F4N4O2
|
1
|
| 1 |
Ki = 6064 nM
|
|
|
|
CP0534907
|
3-(furan-2-yl)-3-(2-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]propan-1-amine
Show/Hide
|
C22H25NO3
|
1
|
| 1 |
Ki = 6100 nM
|
|
|
|
CP0552435
|
3-(4-fluorophenyl)-3-(furan-2-yl)-N-[1-(4-methylphenyl)ethyl]propan-1-amine
Show/Hide
|
C22H24FNO
|
1
|
| 1 |
Ki = 6100 nM
|
|
|
|
CP0539867
|
N-[1-[2-[2,6-di(propan-2-yl)phenoxy]ethyl]piperidin-4-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C25H35FN2O3S
|
1
|
| 1 |
Ki = 6147 nM
|
|
|
|
CP0135185
|
4-[5-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
Ki = 6204 nM
|
|
|
|
CP0853988
|
3-[3-(4-Benzoylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H27FN4O4
|
1
|
| 1 |
Ki = 6216 nM
|
|
|
|
CP0445431
|
(2S)-1-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]benzoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C24H30N4O3
|
1
|
| 1 |
Ki = 6307 nM
|
|
|
|
CP0852189
|
6-Dehydrogingerdione
Show/Hide
|
C17H22O4
|
1
|
| 1 |
Ki = 6530 nM
|
|
|
|
CP0859565
|
1-Dehydro-8-gingerdione
Show/Hide
|
C19H26O4
|
1
|
| 1 |
Ki = 6540 nM
|
|
|
|
CP0376741
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-[2-(4-fluorophenyl)pyridin-3-yl]piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H30FN5O2
|
1
|
| 1 |
Ki = 6631 nM
|
|
|
|
CP0544198
|
6-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C23H24Cl2N8
|
1
|
| 1 |
Ki = 6806 nM
|
|
|
|
CP0381937
|
5-(4-fluorophenyl)-3-[3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H26F2N4O3
|
1
|
| 1 |
Ki = 6862 nM
|
|
|
|
CP0545394
|
4-(3-chlorophenyl)piperazine-1-carboxamide
Show/Hide
|
C11H14ClN3O
|
1
|
| 1 |
Ki = 7014 nM
|
|
|
|
CP0387337
|
N-[1-(4-chlorophenyl)ethyl]-3-(furan-2-yl)-4-phenylbutan-1-amine
Show/Hide
|
C22H24ClNO
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0438624
|
4-[(3-chlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O
|
1
|
| 1 |
Ki = 7505 nM
|
|
|
|
CP0431613
|
4-[(4-chloro-2-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 7688 nM
|
|
|
|
CP0518068
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H32N2O3S
|
1
|
| 1 |
Ki = 8687 nM
|
|
|
|
CP0382745
|
4-(4-methylpiperazin-1-yl)-6-(phenoxymethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6O
|
1
|
| 1 |
Ki = 8726 nM
|
|
|
|
CP0518073
|
N-[1-[2-(5-bromo-2-iodophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C19H22BrIN2O3S
|
1
|
| 1 |
Ki = 8966 nM
|
|
|
|
CP0403509
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-4-fluoro-N-methylbenzenesulfonamide
Show/Hide
|
C24H33FN2O3S
|
1
|
| 1 |
Ki = 9054 nM
|
|
|
|
CP0387335
|
N-[1-(4-chlorophenyl)ethyl]-3-(furan-2-yl)-3-(4-methylphenyl)propan-1-amine
Show/Hide
|
C22H24ClNO
|
1
|
| 1 |
Ki = 9100 nM
|
|
|
|
CP0440390
|
5-chloro-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12ClN3
|
1
|
| 1 |
Ki = 9120 nM
|
|
|
|
CP0392641
|
3-[3-[4-(2,4-difluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H25F3N4O3
|
1
|
| 1 |
Ki = 9167 nM
|
|
|
|
CP0417066
|
1-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C27H30N4O3
|
1
|
| 1 |
Ki = 9473 nM
|
|
|
|
CP0372356
|
6-Dihydroparadol
Show/Hide
|
C17H28O3
|
1
|
| 1 |
Ki = 9530 nM
|
|
|
|
CP0375464
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N,1-dimethylpyrazole-4-sulfonamide
Show/Hide
|
C22H34N4O3S
|
1
|
| 1 |
Ki = 9626 nM
|
|
|
|
CP0372923
|
2-[3-[(2S,5S)-5-[(6-bromo-1H-indol-3-yl)methyl]-3,6-dioxopiperazin-2-yl]propyl]guanidine
Show/Hide
|
C17H21BrN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0845072
|
(cyclo[(6-bromo-8-entryptophan)arginine])
Show/Hide
|
C17H19BrN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391901
|
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14ClN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391904
|
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C14H17N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391907
|
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13ClN2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391908
|
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13FN2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0456120
|
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0144741
|
4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0159204
|
5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0159262
|
5-methyl-4-(1-naphthalen-1-ylsulfonylindol-3-yl)-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C22H19ClN4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0420831
|
4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C19H18ClFN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0423253
|
N-[4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424446
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C20H21ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424449
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C22H21FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435386
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435387
|
N-[4-[1-(benzenesulfonyl)-2-methylindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435391
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-1H-imidazo[1,2-a]pyrimidin-4-ium;bromide
Show/Hide
|
C22H19BrN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435403
|
4-(5-methoxy-1-naphthalen-1-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435405
|
N-[4-[1-(benzenesulfonyl)-5-fluoroindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H19FN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438423
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine;hydrochloride
Show/Hide
|
C22H23ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438428
|
4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440887
|
1-[3-[1-(benzenesulfonyl)indol-3-yl]-2-methyl-6,7-dihydro-5H-imidazo[1,2-a]pyrimidin-8-yl]ethanone
Show/Hide
|
C23H22N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440888
|
2-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazo[1,2-a]pyrimidin-4-ium;bromide
Show/Hide
|
C20H15BrN4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476615
|
1-[5-[1-(benzenesulfonyl)indol-3-yl]-6-methyl-2,3-dihydroimidazo[1,2-a]imidazol-1-yl]ethanone
Show/Hide
|
C22H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489682
|
N-[5-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C19H16N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489683
|
N-[5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489684
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489725
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C19H19ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0519613
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H19FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0521248
|
N-[4-[1-(benzenesulfonyl)indol-4-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0859942
|
3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-sulfonamide
Show/Hide
|
C13H14N4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0900183
|
methyl 3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-carboxylate
Show/Hide
|
C15H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421663
|
5-chloro-3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421833
|
5-ethoxy-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421839
|
3-(3-ethylimidazol-4-yl)-4,5-difluoro-1H-indole
Show/Hide
|
C13H11F2N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0426679
|
4,5-difluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9F2N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541121
|
3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0553532
|
3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H13N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0000082
|
CAS_68647
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0542760
|
2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[2-(2-methoxyphenyl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 10280 nM
|
|
|
|
CP0908603
|
1-(1H-indol-3-yl)-2-(phenylsulfonyl)-1,2-dihydroisoquinoline
Show/Hide
|
C23H18N2O2S
|
1
|
| 1 |
Ki = 10330 nM
|
|
|
|
CP0374185
|
8-Gingerol
Show/Hide
|
C19H30O4
|
1
|
| 1 |
Ki = 11710 nM
|
|
|
|
CP0504617
|
4-[(4-chlorophenyl)methylsulfanyl]-6-fluoro-3-(4-methylphenyl)sulfonylquinoline
Show/Hide
|
C23H17ClFNO2S2
|
1
|
| 1 |
Ki = 11860 nM
|
|
|
|
CP0378964
|
4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-ethylsulfonyl-1,3-thiazole
Show/Hide
|
C20H19ClN2O4S3
|
1
|
| 1 |
Ki = 12200 nM
|
|
|
|
CP0418580
|
N-(3-chlorophenyl)-2-(3-methoxyphenyl)-N-methyl-1-oxoisoquinoline-4-carboxamide
Show/Hide
|
C24H19ClN2O3
|
1
|
| 1 |
Ki = 12490 nM
|
|
|
|
CP0402158
|
4-(4-methylpiperazin-1-yl)-6-[(5-methyl-2-propan-2-ylphenoxy)methyl]-1,3,5-triazin-2-amine
Show/Hide
|
C19H28N6O
|
1
|
| 1 |
Ki = 12530 nM
|
|
|
|
CP0575068
|
2-N-[2-(1H-indol-3-yl)ethyl]-6-(4-phenylpiperazin-1-yl)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C23H26N8
|
1
|
| 1 |
Ki = 12960 nM
|
|
|
|
CP0542764
|
2-N-[2-(1H-indol-3-yl)ethyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C24H28N8O
|
1
|
| 1 |
Ki = 12970 nM
|
|
|
|
CP0845452
|
8-shogaol
Show/Hide
|
C19H28O3
|
1
|
| 1 |
Ki = 13050 nM
|
|
|
|
CP0850785
|
3-Chloro-5-[(4-methylpiperazin-1-yl)methyl]-9H-xanthen-9-one dihydrochloride
Show/Hide
|
C19H22Cl4N2O2
|
1
|
| 1 |
Ki = 13340 nM
|
|
|
|
CP0056178
|
4-fluoranyl-N-(4-oxidanyl-3-quinolin-8-ylsulfanyl-naphthalen-1-yl)benzenesulfonamide
Show/Hide
|
C25H17FN2O3S2
|
1
|
| 1 |
Ki = 13490 nM
|
|
|
|
CP0379116
|
3-(benzenesulfonyl)-6-chloro-N-(4-methylphenyl)quinolin-4-amine
Show/Hide
|
C22H17ClN2O2S
|
1
|
| 1 |
Ki = 13700 nM
|
|
|
|
CP0456106
|
1'-[2-[4-(4-chlorophenoxy)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H28ClN3O2
|
1
|
| 1 |
Ki = 13790 nM
|
|
|
|
CP0375469
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-(cyclopropylmethyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C27H37FN2O3S
|
1
|
| 1 |
Ki = 14030 nM
|
|
|
|
CP0485157
|
1'-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27FN4O
|
1
|
| 1 |
Ki = 14160 nM
|
|
|
|
CP0382743
|
4-[(2-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 14160 nM
|
|
|
|
CP0456105
|
1'-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H28ClN3O
|
1
|
| 1 |
Ki = 14900 nM
|
|
|
|
CP0402155
|
4-[(3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 15070 nM
|
|
|
|
CP0913770
|
3-{3-[4-(Diphenylmethyl)piperazin-1-yl]-2-hydroxypropyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 15150 nM
|
|
|
|
CP0400393
|
N-[(E)-(6-chloro-2,3,4,9-tetrahydrocarbazol-1-ylidene)amino]-4-methylbenzenesulfonamide
Show/Hide
|
C19H18ClN3O2S
|
1
|
| 1 |
Ki = 15560 nM
|
|
|
|
CP0412479
|
(3-Benzo[1,3]dioxol-5-yl-3-phenyl-propyl)-(4-methoxy-benzyl)-amine
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
Ki = 15600 nM
|
|
|
|
CP0856666
|
6-Methoxy-2-[(4-methylpiperazin-1-yl)methyl]-9H-xanthen-9-one dihydrochloride
Show/Hide
|
C20H24Cl2N2O3
|
1
|
| 1 |
Ki = 15840 nM
|
|
|
|
CP0375470
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-(cyclopropylmethyl)-1-methylpyrazole-4-sulfonamide
Show/Hide
|
C25H38N4O3S
|
1
|
| 1 |
Ki = 17770 nM
|
|
|
|
CP0257148
|
6-Shogaol
Show/Hide
|
C17H24O3
|
1
|
| 1 |
Ki = 18020 nM
|
|
|
|
CP0411953
|
5-(3-fluorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30ClFN4O4
|
1
|
| 1 |
Ki = 18290 nM
|
|
|
|
CP0412015
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5-(2-fluorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
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C24H30ClFN4O4
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1
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| 1 |
Ki = 18430 nM
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CP0379117
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1-[3-(benzenesulfonyl)-6-chloroquinolin-4-yl]piperidine-4-carboxamide
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C21H20ClN3O3S
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1
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| 1 |
Ki = 18490 nM
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CP0481865
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N-(5-chloro-2-methylphenyl)-2-(2,4-difluorophenyl)-N-methyl-1-oxoisoquinoline-4-carboxamide
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C24H17ClF2N2O2
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1
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| 1 |
Ki = 19670 nM
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CP0400395
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3-(4-chlorophenyl)sulfonyl-1-(2-methoxyethyl)-4,5-dimethylpyrrol-2-amine
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C15H19ClN2O3S
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1
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| 1 |
Ki = 19890 nM
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CP0504618
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N-(10a-morpholin-4-yl-7,8,9,10-tetrahydro-6bH-naphtho[1,2-b][1]benzofuran-5-yl)benzenesulfonamide
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C26H28N2O4S
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1
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| 1 |
Ki = 20600 nM
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CP0852964
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3-{3-[4-(4-Chlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
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C24H27ClFN3O4
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1
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| 1 |
Ki = 21470 nM
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CP0418579
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2-(benzenesulfonyl)-4,6-diphenylthieno[2,3-b]pyridin-3-amine
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C25H18N2O2S2
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1
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| 1 |
Ki = 21610 nM
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CP0523197
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2-(4-fluorophenyl)sulfonyl-1-(1H-indol-3-yl)-3H-isoquinoline
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C23H17FN2O2S
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1
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| 1 |
Ki = 23510 nM
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CP0544199
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2-N-[2-(2,3-dichloroanilino)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
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C21H22Cl2N8
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1
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| 1 |
Ki = 23590 nM
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CP0147070
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N-(4-hydroxy-3-quinolin-8-ylsulfanylnaphthalen-1-yl)benzenesulfonamide
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C25H18N2O3S2
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1
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| 1 |
Ki = 23740 nM
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CP0413125
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5-(6-oxo-1H-pyridazin-3-yl)-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-2-sulfonamide
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C18H17N3O3S2
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1
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| 1 |
Ki = 24070 nM
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CP0400006
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4-benzyl-12-bromo-1,4-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-9(16),10(15),11,13-tetraene
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C21H21BrN2
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1
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| 1 |
Ki = 26360 nM
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CP0431614
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4-[(4-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C16H22N6O
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1
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| 1 |
Ki = 28510 nM
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CP0438306
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4-methyl-4-(5-methylfuran-2-yl)-N-[[4-(trifluoromethyl)phenyl]methyl]pentan-2-amine
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C19H24F3NO
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1
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| 1 |
Ki = 31400 nM
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CP0548183
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N-[(3,4-dimethoxyphenyl)methyl]-2-[2-ethyl-2-methyl-4-(4-methylphenyl)oxan-4-yl]ethanamine
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C26H37NO3
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1
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| 1 |
Ki = 36800 nM
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CP0542759
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4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyanilino)ethyl]-1,3,5-triazine-2,4,6-triamine
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C22H26N8O
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1
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| 1 |
Ki = 37040 nM
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CP0542995
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2-N-(2-anilinoethyl)-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
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C21H24N8
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1
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| 1 |
Ki = 38220 nM
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CP0383123
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N-[1-[2-(4-chlorophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
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C19H23ClN2O3S
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1
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| 1 |
Ki = 38290 nM
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CP0387336
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N-benzyl-2-[2-ethyl-2-methyl-4-(4-methylphenyl)oxan-4-yl]ethanamine
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C24H33NO
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1
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| 1 |
Ki = 41800 nM
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CP0456108
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1'-[2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
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C24H27ClN4O2
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1
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| 1 |
Ki = 48240 nM
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CP0412402
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1'-[2-[4-(4-fluorophenyl)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
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C24H28FN3O
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1
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| 1 |
Ki = 52010 nM
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CP0469658
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N-[1-[2-(4-bromophenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
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C19H23BrN2O3S
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1
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| 1 |
Ki = 52610 nM
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CP0647624
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SID26756481
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C17H26O4
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1
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| 1 |
Ki > 100000 nM
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CP0371912
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2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinone
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C23H29N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0383839
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1-[5-(4-Phenylpiperazin-1-yl)pentyl]-1,3-dihydro-2H-indol-2-one
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C23H29N3O
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1
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| 1 |
Ki > 1000 nM
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CP0383841
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1-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethyl]-1,3-dihydro-2H-indol-2-one
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C19H20N2O
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1
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| 1 |
Ki > 1000 nM
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CP0424211
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1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one
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C23H29N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0439675
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1-{5-[4-(2-Methoxyphenyl)piperazin-1-yl]pentyl}-1,3-dihydro-2H-indol-2-one
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C24H31N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0459793
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1-[4-(4-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H-indol-2-one
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C23H28N2O
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1
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| 1 |
Ki > 1000 nM
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CP0493335
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2-[5-(4-Phenylpiperazin-1-yl)pentyl]isoindolin-1-one
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C23H29N3O
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1
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| 1 |
Ki > 1000 nM
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CP0493810
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1-[4-(3-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H-indol-2-one
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C23H28N2O
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1
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| 1 |
Ki > 1000 nM
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CP0506464
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1-(3-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)-1,3-dihydro-2H-indol-2-one
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C30H29N3O
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1
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| 1 |
Ki > 1000 nM
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CP0522888
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1-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)propyl]-1,3-dihydro-2H-indol-2-one
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C20H22N2O
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1
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| 1 |
Ki > 1000 nM
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CP0420922
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(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-3-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]imidazolidine-2,4-dione
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C29H34Cl2N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0548401
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2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-isoindole-1,3-dione
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C20H21N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0572400
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2-[2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl]isoindole-1,3-dione
Show/Hide
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C21H23N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0170807
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5-chloro-3-ethyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
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C23H23ClN4O2S2
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1
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| 1 |
Ki < 3981.07 nM
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CP0096286
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(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
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C18H28N2O3S
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2
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| 1 |
Ki > 5000 nM
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| 2 |
Ki < 10000 nM
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CP0089986
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STEPHOLIDINE
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C19H21NO4
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1
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| 1 |
Ki > 5000 nM
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CP0105348
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(S)-2,9-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-3,10-diol
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C19H21NO4
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1
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| 1 |
Ki > 5000 nM
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CP0181209
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(-)-Tetrahydroberberine
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C20H21NO4
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1
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| 1 |
Ki > 5000 nM
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CP0230384
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(-)-Tetrahydropalmatine
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C21H25NO4
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1
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| 1 |
Ki > 5000 nM
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CP0377500
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(13aS)-12-(hydroxymethyl)-3,9,11-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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C21H25NO5
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1
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| 1 |
Ki > 5000 nM
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CP0440159
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(1S)-17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-ol
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C19H19NO4
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1
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| 1 |
Ki > 5000 nM
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CP0443216
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(1S)-16-methoxy-5-oxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-17-ol
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C20H21NO3
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1
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| 1 |
Ki > 5000 nM
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CP0317609
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1,1-dioxo-2-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1,2-benzothiazol-3-one
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C20H20F3N3O3S
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1
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| 1 |
Ki > 5000 nM
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CP0156235
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3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
Show/Hide
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C18H30N2O2S
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1
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| 1 |
Ki < 7943.28 nM
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CP0425239
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1-[4-(4-chloro-3-fluorophenoxy)but-2-ynyl]-4-[2-(4-methoxyphenyl)phenyl]piperazine
Show/Hide
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C27H26ClFN2O2
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1
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| 1 |
Ki > 8000 nM
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