Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
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 PubChem ID
CID: 145976696
Canonical SMILES
COc1ccccc1N1CCN(CCOCCOc2c(C)cc(C)cc2C)CC1.Cl.Cl
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Compound Formula C24H36Cl2N2O3
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 56.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS