General Information of the Compound
| Compound ID |
CP0485159
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| Compound Name |
1'-[2-(4-phenylpiperazin-1-yl)ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
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| Structure |
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| Formula |
C23H28N4O
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| Molecular Weight |
376.504
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| Canonical SMILES |
O=C1Nc2ccccc2C11CCN(CCN2CCN(CC2)c2ccccc2)C1
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| InChI |
InChI=1S/C23H28N4O/c28-22-23(20-8-4-5-9-21(20)24-22)10-11-26(18-23)13-12-25-14-16-27(17-15-25)19-6-2-1-3-7-19/h1-9H,10-18H2,(H,24,28)
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| InChIKey |
XMJQXVBVBFLUHR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Protein ID: PT00941, 5-hydroxytryptamine receptor 7