General Information of the Compound
Compound ID
CP0485849
Compound Name
N-[3-[4-[4-(propan-2-ylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide
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Structure
Formula
C19H32N4O3S
Molecular Weight
396.557
Canonical SMILES
CC(C)S(=O)(=O)NCCCCN1CCN(CC1)c1cccc(NC(C)=O)c1
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InChI
InChI=1S/C19H32N4O3S/c1-16(2)27(25,26)20-9-4-5-10-22-11-13-23(14-12-22)19-8-6-7-18(15-19)21-17(3)24/h6-8,15-16,20H,4-5,9-14H2,1-3H3,(H,21,24)
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InChIKey
CPBIWHVJLGAGPZ-UHFFFAOYSA-N
Physicochemical Property
logP
1.875
Rotatable Bonds
9
Heavy Atom Count
27
Polar Areas
81.75
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10318597
SID: 15327912
ChEMBL ID
CHEMBL209985
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 24 nM
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