Brief Information of the Compound and Protein
Compound Name
4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione
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PubChem ID
CID: 55191
SID: 14925895
Canonical SMILES
CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C1
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Compound Formula C19H29N5O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 114 nM
2 Kd = 79.43 nM
3 Ki = 31.8 nM