Brief Information of the Compound and Protein
Compound Name
[(1S)-16,18-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-19-yl]methanol
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PubChem ID
CID: 70690497
SID: 163442739
Canonical SMILES
COc1cc(OC)c2CN3CCc4cc5OCOc5cc4[C@@H]3Cc2c1CO
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Compound Formula C21H23NO5
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 758.03 nM
   TI
   LI
   LO
   TS
2
Ki = 599.89 nM
   TI
   LI
   LO
   TS