Brief Information of the Compound and Protein
Compound Name
US9359372, DC037032
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PubChem ID
CID: 71474026
SID: 163442109
Canonical SMILES
COc1ccc(OC)c2CN3CCc4cc5OCCOc5cc4[C@@H]3Cc12
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Compound Formula C21H23NO4
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 51.53 nM
   TI
   LI
   LO
   TS
2
Ki = 40.59 nM
   TI
   LI
   LO
   TS