General Information of the Compound
| Compound ID |
CP0030899
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| Compound Name |
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
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| Synonyms |
(Chlorotrityl)imidazole
1-(o-Chlorotrityl)imidazole
B 5097
Bay b 9057
Bay-B 5097
Bayer Brand 1 of Clotrimazole
Bayer Brand 2 of Clotrimazole
C 6019
Cancap-VT (TN)
Candid - V Gel (TN)
Candid Vaginal (TN)
Candinil (TN)
Canesten
Canesten (TN)
Canesten 1-Day Cream Combi-Pak
Canesten 1-Day Therapy
Canesten 3-Day Therapy
Canesten 6-Day Therapy
Canesten Combi-Pak 1-Day Therapy
Canesten Combi-Pak 3-Day Therapy
Canesten Cream
Canesten Solution
Canestene
Canestine
Canifug
Chlotrimazole
Cimitidine
Clobrate VT (TN)
Clomatin
Clotrimaderm
Clotrimazol
Clotrimazol [INN-Spanish]
Clotrimazole
Clotrimazole (JP15/USP/INN)
Clotrimazole Schering Brand
Clotrimazole [USAN:INN:BAN:JAN]
Clotrimazolum
Clotrimazolum [INN-Latin]
Clotrimeizol
Cutistad
DRG-0072
Desamix F
Empecid
Esparol
FB 5097
FB b 5097
Fem Care
FemCare
Gino-Lotremine
Gyne lotrimin
Gyne-Lotrimin
Gyne-Lotrimin 3
Gyne-Lotrimin 3 Combination Pack
Gyne-Lotrimin Combination Pack
Gynix
Kanesten
Klotrimazole
Lotrimax
Lotrimin
Lotrimin (TN)
Lotrimin AF Cream
Lotrimin AF Jock-Itch Cream
Lotrimin AF Lotion
Lotrimin AF Solution
Lotrimin Af
Lotrimin Cream
Lotrimin Lotion
Lotrimin Solution
Mono-baycuten
Monobaycuten
Mycelax
Mycelex
Mycelex (TN)
Mycelex 7
Mycelex Cream
Mycelex G
Mycelex OTC
Mycelex Solution
Mycelex Troches
Mycelex Twin Pack
Mycelex-7
Mycelex-7 Combination Pack
Mycelex-G
Mycelex: MycosporinRimazole
Myclo Cream
Myclo Solution
Myclo Spray Solution
Myclo-Gyne
Mycofug
Mycosporin
Mykosporin
Nalbix
Neo-Zol Cream
Pan-Fungex
Pedisafe
Rimazole
Schering Brand of Clotrimazole
Stiemazol
Tibatin
Trimysten
Trivagizole 3
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| Structure |
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| Formula |
C22H17ClN2
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| Molecular Weight |
344.845
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| Canonical SMILES |
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1
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| InChI |
InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
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| InChIKey |
VNFPBHJOKIVQEB-UHFFFAOYSA-N
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| CAS |
117829-71-7
23593-75-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00820, Acetylcholinesterase
Protein ID: PT06079, ATP-dependent translocase ABCB1
Protein ID: PT01685, ATP-dependent translocase ABCB1
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT01049, Cytochrome P450 2C19
Protein ID: PT00905, Cytochrome P450 2C9
Protein ID: PT00986, Cytochrome P450 3A4
Protein ID: PT00967, Glucocorticoid receptor
Protein ID: PT03388, Indoleamine 2,3-dioxygenase 1
Protein ID: PT06300, Indoleamine 2,3-dioxygenase 2
Protein ID: PT00984, Intermediate conductance calcium-activated potassium channel protein 4
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT00901, Prostaglandin G/H synthase 2
Protein ID: PT03795, Solute carrier family 22 member 1
Protein ID: PT04908, Transient receptor potential cation channel subfamily M member 2
Protein ID: PT01102, Voltage-dependent L-type calcium channel subunit alpha-1C
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000150 | HaCaT | Homo sapiens (Human) | 1 |
| 1 |
LD50 = 40000 nM
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TI
LI
LO
TS
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Clinical Information about the Compound