General Information of the Cell Line
Cell Line ID
CL000106
Cell Line Name
OCI-Ly3
Synonyms
OCI-LY3
OCI-ly3
OCI-LY-3
Oci-Ly-3
OCI-Ly 3
OCILY-3
OCI-Ly03
OCI Ly3
OCILY3
Ly3
LY3
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_8800
Tissue Information
Bone marrow
Disease
Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03110, MALT lymphoma-associated translocation
 Protein Info 
Compound ID Compound Name Compound Formula
CP0359950
 Compound Info 
1-(3-aminopyridin-2-yl)-N-[3-chloro-4-(triazol-2-yl)phenyl]piperidine-4-carboxamide
   Show/Hide
C19H20ClN7O
  1
1
EC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0389888
 Compound Info 
N-[3-chloro-4-[3-(methylcarbamoyl)-1,2,4-triazol-1-yl]phenyl]-1-(3-chloropyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C21H21Cl2N7O2
  1
1
EC50 = 210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074453
 Compound Info 
1-(3-chloropyridin-2-yl)-N-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]piperidine-4-carboxamide
   Show/Hide
C18H17Cl2N7O
  1
1
EC50 = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261160
 Compound Info 
N-(3-chloro-4-fluorophenyl)-1-(3-chloropyrazin-2-yl)piperidine-4-carboxamide
   Show/Hide
C16H15Cl2FN4O
  1
1
EC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475290
 Compound Info 
N-(5-chloro-6-methoxypyridin-3-yl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C17H18Cl2N4O2
  1
1
EC50 = 450 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0359945
 Compound Info 
1-(3-aminopyridin-2-yl)-N-(3-chloro-4-fluorophenyl)piperidine-4-carboxamide
   Show/Hide
C17H18ClFN4O
  1
1
EC50 = 540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0536081
 Compound Info 
1-(3-aminopyridin-2-yl)-N-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]piperidine-4-carboxamide
   Show/Hide
C18H19ClN8O
  1
1
EC50 = 560 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261159
 Compound Info 
N-(3-chloro-4-fluorophenyl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C17H16Cl2FN3O
  1
1
EC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0359944
 Compound Info 
N-(3-chloro-4-fluorophenyl)-1-(3-cyanopyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C18H16ClFN4O
  1
1
EC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236381
 Compound Info 
N-(3-chlorophenyl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C17H17Cl2N3O
  1
1
EC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0086265
 Compound Info 
N-(3-chloro-4-fluorophenyl)-1-pyrimidin-2-ylpiperidine-4-carboxamide
   Show/Hide
C16H16ClFN4O
  1
1
EC50 = 5400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0327621
 Compound Info 
N-(3-chloro-4-fluorophenyl)-1-phenylpiperidine-4-carboxamide
   Show/Hide
C18H18ClFN2O
  1
1
EC50 = 9200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532994
 Compound Info 
1-(5-chloro-6-methoxypyridin-3-yl)-3-[6-cyano-4-[(3S)-3-methylmorpholin-4-yl]quinolin-3-yl]urea
   Show/Hide
C22H21ClN6O3
  1
1
IC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402090
 Compound Info 
(2R,4R)-1-(3-bromopyridin-2-yl)-N-(3-chloro-4-methoxyphenyl)-2-methylpiperidine-4-carboxamide
   Show/Hide
C19H21BrClN3O2
  1
1
IC50 = 70 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575357
 Compound Info 
1-[2-chloro-7-(3,3-dimethylmorpholin-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]-3-(5-chloro-6-methoxypyridin-3-yl)urea
   Show/Hide
C19H21Cl2N7O3
  1
1
IC50 = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0431592
 Compound Info 
1-(3-bromopyridin-2-yl)-N-(3-chloro-4-methoxyphenyl)-2-methylpiperidine-4-carboxamide
   Show/Hide
C19H21BrClN3O2
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0554883
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-[6-cyano-4-[(3S)-3-methylmorpholin-4-yl]quinolin-3-yl]urea
   Show/Hide
C23H22ClN5O3
  1
1
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0258300
 Compound Info 
1-[2-chloro-7-[(3S,5S)-3,5-dimethylmorpholin-4-yl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)pyridin-4-yl]urea
   Show/Hide
C19H19ClF3N7O2
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0345345
 Compound Info 
1-(5-chloro-6-methoxypyridin-3-yl)-3-[6-cyano-4-[methyl(oxan-4-yl)amino]quinolin-3-yl]urea
   Show/Hide
C23H23ClN6O3
  1
1
IC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402170
 Compound Info 
N-(3-chloro-4-methoxyphenyl)-2-methyl-1-(3-methylpyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C20H24ClN3O2
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0512707
 Compound Info 
1-[2-chloro-7-(3,3-dimethylmorpholin-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)pyridin-4-yl]urea
   Show/Hide
C19H19ClF3N7O2
  1
1
IC50 = 280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528642
 Compound Info 
1-[2-chloro-7-[(3S,5S)-3,5-dimethylmorpholin-4-yl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-(5-chloro-6-methoxypyridin-3-yl)urea
   Show/Hide
C19H21Cl2N7O3
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575356
 Compound Info 
1-(6-bromo-4-chloroquinolin-3-yl)-3-(3-chloro-4-methoxyphenyl)urea
   Show/Hide
C17H12BrCl2N3O2
  1
1
IC50 = 510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0382831
 Compound Info 
N-(3-chloro-4-methoxyphenyl)-1-(3-methylpyridin-2-yl)piperidine-4-carboxamide
   Show/Hide
C19H22ClN3O2
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573419
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-[6-cyano-4-[methyl(oxan-4-yl)amino]quinolin-3-yl]urea
   Show/Hide
C24H24ClN5O3
  1
1
IC50 = 670 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0554884
 Compound Info 
1-[2-bromo-7-[(3S)-3-methylmorpholin-4-yl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-(5-chloro-6-methoxypyridin-3-yl)urea
   Show/Hide
C18H19BrClN7O3
  1
1
IC50 = 740 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0512706
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)urea
   Show/Hide
C17H16ClFN2O3
  1
1
IC50 = 1250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0431590
 Compound Info 
N-(3-chloro-4-methoxyphenyl)-1-thieno[3,2-c]pyridin-4-ylpiperidine-4-carboxamide
   Show/Hide
C20H20ClN3O2S
  1
1
IC50 = 1550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565126
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-(6-cyano-3,4-dihydro-2H-chromen-3-yl)urea
   Show/Hide
C18H16ClN3O3
  1
1
IC50 = 1920 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0345344
 Compound Info 
1-[(3R)-6-bromo-3,4-dihydro-2H-chromen-3-yl]-3-[3-chloro-4-(1,2,4-triazol-1-yl)phenyl]urea
   Show/Hide
C18H15BrClN5O2
  1
1
IC50 = 1960 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0142584
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-(3,4-dihydro-2H-chromen-3-yl)urea
   Show/Hide
C17H17ClN2O3
  1
1
IC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532993
 Compound Info 
1-(6-bromo-3,4-dihydro-2H-chromen-3-yl)-3-(5-chloro-6-methoxypyridin-3-yl)urea
   Show/Hide
C16H15BrClN3O3
  1
1
IC50 = 3540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0256471
 Compound Info 
1-(3-chloro-4-methoxyphenyl)-3-(6-fluoro-3,4-dihydro-2H-thiochromen-3-yl)urea
   Show/Hide
C17H16ClFN2O2S
  1
1
IC50 = 4270 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528641
 Compound Info 
1-(6-bromoquinolin-3-yl)-3-(3-chloro-4-methoxyphenyl)urea
   Show/Hide
C17H13BrClN3O2
  1
1
IC50 = 4820 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT05222, NF-kappa-B inhibitor alpha
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0074453
 Compound Info 
1-(3-chloropyridin-2-yl)-N-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]piperidine-4-carboxamide
   Show/Hide
 C18H17Cl2N7O  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0331609
 Compound Info 
(12S,14S,17E)-23-benzyl-7-chloro-12-(hydroxymethyl)-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C31H31ClN6O4  1
1
GI50 = 12589.25 nM
   TI
   LI
   LO
   TS
CP0412952
 Compound Info 
(12S,14S,17E)-7-chloro-12-(hydroxymethyl)-23-[(3-methoxyphenyl)methyl]-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C32H33ClN6O5  1
1
GI50 > 31622.78 nM
   TI
   LI
   LO
   TS
CP0461715
 Compound Info 
(12S,14S,17E)-7-chloro-12-(hydroxymethyl)-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C24H25ClN6O4  1
1
GI50 = 1995.26 nM
   TI
   LI
   LO
   TS
CP0461716
 Compound Info 
(12S,14S,17E)-7-chloro-12-(hydroxymethyl)-23-[(4-methylphenyl)methyl]-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C32H33ClN6O4  1
1
GI50 = 15848.93 nM
   TI
   LI
   LO
   TS
CP0461746
 Compound Info 
(12S,14S,17E)-7-chloro-23-[(3,3-difluorocyclobutyl)methyl]-12-(hydroxymethyl)-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C29H31ClF2N6O4  1
1
GI50 = 12589.25 nM
   TI
   LI
   LO
   TS
CP0521736
 Compound Info 
(12S,14S,17E)-7-chloro-12-(hydroxymethyl)-23-methyl-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C25H27ClN6O4  1
1
GI50 = 6309.57 nM
   TI
   LI
   LO
   TS
CP0558756
 Compound Info 
(12S,14S,17E)-7-chloro-12-(hydroxymethyl)-23-(pyridin-4-ylmethyl)-15,20-dioxa-2,4,5,9,11,23-hexazahexacyclo[19.7.1.13,10.111,14.04,8.022,27]hentriaconta-1(28),3(31),5,7,9,17,21(29),22(27)-octaen-24-one
   Show/Hide
 C30H30ClN7O4  1
1
GI50 = 12589.25 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone marrow)
Cell Line Name Organism Disease
NB4
 Cell Line Info 
Homo sapiens (Human) Acute promyelocytic leukemia with PML-RARA
UT-7/Epo
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
UT-7
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
KG-1
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
KG-1a
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
RS4;11
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
Rh30
 Cell Line Info 
Homo sapiens (Human) Alveolar rhabdomyosarcoma
MEG-01
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
697
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SUP-B15
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
HAP1
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
OCI-Ly1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma
TMD8
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
OCI-Ly19
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
TF-1
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
L-540
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
NCI-H345
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H526
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
Z-138
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
CAL-1 [Human melanoma]
 Cell Line Info 
Homo sapiens (Human) Melanoma
SH-SY5Y
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SH-EP1
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-SH
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)-C
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(1)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-AS
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
GI-CA-N
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
LSCC-HD11
 Cell Line Info 
Gallus gallus (Chicken) -
IM-9
 Cell Line Info 
Homo sapiens (Human) -
LAD 2
 Cell Line Info 
Homo sapiens (Human) -
UE6E7T-2
 Cell Line Info 
Homo sapiens (Human) -
RBC
 Cell Line Info 
Homo sapiens (Human) -
Ba/F3
 Cell Line Info 
Mus musculus (Mouse) -
FDC-P1
 Cell Line Info 
Mus musculus (Mouse) -
S21
 Cell Line Info 
Mus musculus (Mouse) -
ANA-1 [Mouse macrophage]
 Cell Line Info 
Mus musculus (Mouse) -
Y16
 Cell Line Info 
Mus musculus (Mouse) -
32D
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 FLT3-ITD
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 c-Kit D816V
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized C57BL/6
 Cell Line Info 
Mus musculus (Mouse) -
BaF3-BCL
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 NPM-ALK
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized BALB/c
 Cell Line Info 
Mus musculus (Mouse) -