General Information of the Cell Line
Cell Line ID
CL000755
Cell Line Name
Ba/F3 c-Kit D816V
Category
Factor-dependent cell line
Organism
Mus musculus (Mouse)
Tissue Information
Bone marrow
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
 Protein Info 
Compound ID Compound Name Compound Formula
CP0254853
 Compound Info 
(NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium
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C18H17N2O+
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0280315
 Compound Info 
5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol
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C17H14N2O
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0483641
 Compound Info 
1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-ol
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C24H30N4O
  1
1
IC50 < 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0559614
 Compound Info 
2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium
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C23H28N3O+
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0051733
 Compound Info 
5,11-dimethyl-2H-pyrido[4,3-b]carbazole
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C17H14N2
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0541581
 Compound Info 
9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
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C17H13BrN2
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0232374
 Compound Info 
9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
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C18H16N2O
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0483642
 Compound Info 
N',N'-diethyl-N-(2-methyl-6,15,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1,3(8),4,6,9,11(16),12,14-octaen-7-yl)propane-1,3-diamine
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C22H27N5
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0483638
 Compound Info 
N',N'-diethyl-N-(9-methoxy-5-methyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine
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C24H30N4O
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0002778
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
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C29H31N7O
  1
1
IC50 = 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone marrow)
Cell Line Name Organism Disease
NB4
 Cell Line Info 
Homo sapiens (Human) Acute promyelocytic leukemia with PML-RARA
UT-7/Epo
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
UT-7
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
KG-1
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
KG-1a
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
RS4;11
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
Rh30
 Cell Line Info 
Homo sapiens (Human) Alveolar rhabdomyosarcoma
MEG-01
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
697
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SUP-B15
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
HAP1
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
OCI-Ly1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma
OCI-Ly3
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
TMD8
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
OCI-Ly19
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
TF-1
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
L-540
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
NCI-H345
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H526
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
Z-138
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
CAL-1 [Human melanoma]
 Cell Line Info 
Homo sapiens (Human) Melanoma
SH-SY5Y
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SH-EP1
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-SH
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)-C
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(1)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-AS
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
GI-CA-N
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
LSCC-HD11
 Cell Line Info 
Gallus gallus (Chicken) -
IM-9
 Cell Line Info 
Homo sapiens (Human) -
LAD 2
 Cell Line Info 
Homo sapiens (Human) -
UE6E7T-2
 Cell Line Info 
Homo sapiens (Human) -
RBC
 Cell Line Info 
Homo sapiens (Human) -
Ba/F3
 Cell Line Info 
Mus musculus (Mouse) -
FDC-P1
 Cell Line Info 
Mus musculus (Mouse) -
S21
 Cell Line Info 
Mus musculus (Mouse) -
ANA-1 [Mouse macrophage]
 Cell Line Info 
Mus musculus (Mouse) -
Y16
 Cell Line Info 
Mus musculus (Mouse) -
32D
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 FLT3-ITD
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized C57BL/6
 Cell Line Info 
Mus musculus (Mouse) -
BaF3-BCL
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 NPM-ALK
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized BALB/c
 Cell Line Info 
Mus musculus (Mouse) -