General Information of the Cell Line
Cell Line ID
CL000289
Cell Line Name
SK-N-SH
Synonyms
SK N SH
SKN-SH
SK-NSH
SKNSH
NSH
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0531
Tissue Information
Bone marrow
Disease
Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01014, Cysteine protease CPP32
 Protein Info 
Compound ID Compound Name Compound Formula
CP0036823
 Compound Info 
(-)-etoposide
   Show/Hide
C29H32O13
  1
1
IC50 < 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00951, Cadherin family member 12
 Protein Info 
Protein ID: PT01206, Histamine H1 receptor
 Protein Info 
Protein ID: PT01515, Mu-type opioid receptor
 Protein Info 
Protein ID: PT01266, Muscarinic acetylcholine receptor M3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0086626
 Compound Info 
(1R,3aR,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-9-hydroxy-3a,5a,5b,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-8-carboxylic acid
   Show/Hide
 C30H48O3  1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0209125
 Compound Info 
1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
   Show/Hide
 C12H11N5O2S  1
1
CC50 = 9900 nM
   TI
   LI
   LO
   TS
CP0398971
 Compound Info 
1-ethyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C11H11N7O2  1
1
CC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0401010
 Compound Info 
1-butyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C16H17N5O2  2
1
CC50 = 9800 nM
   TI
   LI
   LO
   TS
2
EC50 = 490 nM
   TI
   LI
   LO
   TS
CP0407532
 Compound Info 
(2Z)-N-[3-(2,6-dimethylpiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C18H24ClN3O3  1
1
CC50 = 36200 nM
   TI
   LI
   LO
   TS
CP0407533
 Compound Info 
5-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
   Show/Hide
 C16H19ClFN3O3  1
1
CC50 = 62400 nM
   TI
   LI
   LO
   TS
CP0427354
 Compound Info 
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-1,3-benzothiazole-2-carboximidoyl chloride
   Show/Hide
 C16H20ClN3O2S  1
1
CC50 = 26500 nM
   TI
   LI
   LO
   TS
CP0427355
 Compound Info 
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-6-methyl-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C17H22ClN3O3  1
1
CC50 = 28000 nM
   TI
   LI
   LO
   TS
CP0429669
 Compound Info 
1-butyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
   Show/Hide
 C15H17N5O3S  1
1
EC50 = 190 nM
   TI
   LI
   LO
   TS
CP0429670
 Compound Info 
1-butyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
   Show/Hide
 C14H16N6O3  1
1
CC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0431030
 Compound Info 
1-ethyl-6-methyl-3-(5-methylfuran-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
   Show/Hide
 C13H13N5O4  1
1
CC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0431038
 Compound Info 
1-ethyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
   Show/Hide
 C12H12N6O3  1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CP0431039
 Compound Info 
3-(1H-benzo[d]imidazol-2-yl)-1-butyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C17H17N7O2  1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0438801
 Compound Info 
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-5-methyl-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C17H22ClN3O3  1
1
CC50 = 34600 nM
   TI
   LI
   LO
   TS
CP0439330
 Compound Info 
3-(benzo[d]thiazol-2-yl)-1-isobutyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C17H16N6O2S  2
1
CC50 = 3700 nM
   TI
   LI
   LO
   TS
2
EC50 = 270 nM
   TI
   LI
   LO
   TS
CP0454257
 Compound Info 
1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C13H13N5O2S  2
1
CC50 = 63500 nM
   TI
   LI
   LO
   TS
2
EC50 = 1330 nM
   TI
   LI
   LO
   TS
CP0471685
 Compound Info 
(Z,2R)-6-(1,3-benzoxazol-2-yl)-6-chloro-1-[propan-2-yl(propyl)amino]hex-5-en-2-ol
   Show/Hide
 C19H27ClN2O2  1
1
CC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0474588
 Compound Info 
(2Z)-N-[3-(3,5-dimethylpiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C18H24ClN3O3  1
1
CC50 = 34000 nM
   TI
   LI
   LO
   TS
CP0474640
 Compound Info 
3-(benzo[d]thiazol-2-yl)-1-benzyl-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C20H14N6O2S  1
1
CC50 = 5600 nM
   TI
   LI
   LO
   TS
CP0491210
 Compound Info 
1-ethyl-6-methyl-3-(5-methylfuran-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C13H13N5O3  1
1
CC50 = 8200 nM
   TI
   LI
   LO
   TS
CP0496180
 Compound Info 
1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine 4-oxide
   Show/Hide
 C13H13N5O3S  2
1
CC50 = 27200 nM
   TI
   LI
   LO
   TS
2
EC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0496181
 Compound Info 
1-butyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C13H15N7O2  1
1
CC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0496196
 Compound Info 
1-butyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C15H17N5O2S  1
1
CC50 = 18200 nM
   TI
   LI
   LO
   TS
CP0498237
 Compound Info 
1-ethyl-6-methyl-3-(1H-pyrrol-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
   Show/Hide
 C12H12N6O2  2
1
CC50 = 4300 nM
   TI
   LI
   LO
   TS
2
EC50 = 680 nM
   TI
   LI
   LO
   TS
CP0498383
 Compound Info 
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C16H20ClN3O3  1
1
CC50 = 26000 nM
   TI
   LI
   LO
   TS
CP0498384
 Compound Info 
(2Z)-N-[3-(3-fluoropiperidin-1-yl)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C16H19ClFN3O3  1
1
CC50 = 49800 nM
   TI
   LI
   LO
   TS
CP0498728
 Compound Info 
(2Z)-N-[3-(dibutylamino)-2-hydroxypropoxy]-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C19H28ClN3O3  1
1
CC50 = 41000 nM
   TI
   LI
   LO
   TS
CP0504814
 Compound Info 
(2Z)-N-(2-hydroxy-3-pyrrolidin-1-ylpropoxy)-1,3-benzothiazole-2-carboximidoyl chloride
   Show/Hide
 C15H18ClN3O2S  1
1
CC50 = 31100 nM
   TI
   LI
   LO
   TS
CP0506150
 Compound Info 
4-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
   Show/Hide
 C16H19ClFN3O3  1
1
CC50 = 20300 nM
   TI
   LI
   LO
   TS
CP0506151
 Compound Info 
6-(N,N-dimethylsulfamoyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride
   Show/Hide
 C18H25ClN4O5S  1
1
CC50 = 42400 nM
   TI
   LI
   LO
   TS
CP0509635
 Compound Info 
(2Z)-N-[2-hydroxy-3-[2-hydroxyethyl(propan-2-yl)amino]propoxy]-1,3-benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C16H22ClN3O4  1
1
CC50 = 30600 nM
   TI
   LI
   LO
   TS
CP0509654
 Compound Info 
(2Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)benzo[e][1,3]benzoxazole-2-carboximidoyl chloride
   Show/Hide
 C20H22ClN3O3  1
1
CC50 = 17400 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone marrow)
Cell Line Name Organism Disease
NB4
 Cell Line Info 
Homo sapiens (Human) Acute promyelocytic leukemia with PML-RARA
UT-7/Epo
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
UT-7
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
KG-1
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
KG-1a
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
RS4;11
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
Rh30
 Cell Line Info 
Homo sapiens (Human) Alveolar rhabdomyosarcoma
MEG-01
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
697
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SUP-B15
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
HAP1
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
OCI-Ly1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma
OCI-Ly3
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
TMD8
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
OCI-Ly19
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
TF-1
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
L-540
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
NCI-H345
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H526
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
Z-138
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
CAL-1 [Human melanoma]
 Cell Line Info 
Homo sapiens (Human) Melanoma
SH-SY5Y
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SH-EP1
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)-C
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(1)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-AS
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
GI-CA-N
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
LSCC-HD11
 Cell Line Info 
Gallus gallus (Chicken) -
IM-9
 Cell Line Info 
Homo sapiens (Human) -
LAD 2
 Cell Line Info 
Homo sapiens (Human) -
UE6E7T-2
 Cell Line Info 
Homo sapiens (Human) -
RBC
 Cell Line Info 
Homo sapiens (Human) -
Ba/F3
 Cell Line Info 
Mus musculus (Mouse) -
FDC-P1
 Cell Line Info 
Mus musculus (Mouse) -
S21
 Cell Line Info 
Mus musculus (Mouse) -
ANA-1 [Mouse macrophage]
 Cell Line Info 
Mus musculus (Mouse) -
Y16
 Cell Line Info 
Mus musculus (Mouse) -
32D
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 FLT3-ITD
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 c-Kit D816V
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized C57BL/6
 Cell Line Info 
Mus musculus (Mouse) -
BaF3-BCL
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 NPM-ALK
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized BALB/c
 Cell Line Info 
Mus musculus (Mouse) -