General Information of the Cell Line
Cell Line ID
CL000519
Cell Line Name
NB4
Synonyms
NB-4
NB.4
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0005
Tissue Information
Bone marrow
Disease
Acute promyelocytic leukemia with PML-RARA (NCIt: C3182)
Acute promyelocytic leukemia (ORDO: Orphanet_520)
Table of Molecular Bioactivities Related to the Cell Line
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007430
 Compound Info 
IBRUTINIB
   Show/Hide
 C25H24N6O2  1
1
GI50 = 3000 nM
   TI
   LI
   LO
   TS
CP0086044
 Compound Info 
(E)-N-hydroxy-3-(4-phenylphenyl)prop-2-enamide
   Show/Hide
 C15H13NO2  1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0140921
 Compound Info 
(E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)-acrylic acid
   Show/Hide
 C25H26O3  1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
CP0204175
 Compound Info 
(E)-N-hydroxy-3-[3-(4-hydroxyphenyl)phenyl]prop-2-enamide
   Show/Hide
 C15H13NO3  1
1
IC50 = 2850 nM
   TI
   LI
   LO
   TS
CP0381812
 Compound Info 
5-(Biphenyl-4-yl)-pentanoic acid N-hydroxyamide
   Show/Hide
 C17H19NO2  1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
CP0383413
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C25H19N5O2  1
1
GI50 = 3700 nM
   TI
   LI
   LO
   TS
CP0387825
 Compound Info 
(E)-N-hydroxy-3-[4-[4-(hydroxymethyl)phenyl]phenyl]prop-2-enamide
   Show/Hide
 C16H15NO3  1
1
IC50 = 1810 nM
   TI
   LI
   LO
   TS
CP0407625
 Compound Info 
(E)-N-hydroxy-3-(4-pyridin-4-ylphenyl)prop-2-enamide
   Show/Hide
 C14H12N2O2  1
1
IC50 = 3290 nM
   TI
   LI
   LO
   TS
CP0428395
 Compound Info 
(E)-N-hydroxy-3-[4-(4-hydroxyphenyl)cyclohexyl]prop-2-enamide
   Show/Hide
 C15H19NO3  1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0428396
 Compound Info 
(E)-3-[4-(3-chloro-4-hydroxyphenyl)phenyl]-N-hydroxyprop-2-enamide
   Show/Hide
 C15H12ClNO3  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0439505
 Compound Info 
(E)-N-hydroxy-3-[4-(1H-indol-5-yl)phenyl]prop-2-enamide
   Show/Hide
 C17H14N2O2  1
1
IC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0447341
 Compound Info 
N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(prop-2-enoylamino)anilino]-6-oxopyridin-3-yl]phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide
   Show/Hide
 C36H37N5O5S  1
1
GI50 = 2400 nM
   TI
   LI
   LO
   TS
CP0447342
 Compound Info 
4-tert-butyl-N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(propanoylamino)anilino]-6-oxopyridin-3-yl]phenyl]benzamide
   Show/Hide
 C38H43N5O5  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0467528
 Compound Info 
4-(dimethylamino)-N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(prop-2-enoylamino)anilino]-6-oxopyridin-3-yl]phenyl]benzamide
   Show/Hide
 C36H38N6O5  1
1
GI50 = 1900 nM
   TI
   LI
   LO
   TS
CP0472278
 Compound Info 
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[1-[2-chloro-4-(2-morpholin-4-ylethoxy)phenyl]triazol-4-yl]phenyl]urea
   Show/Hide
 C28H32ClN7O4  1
1
GI50 > 3000 nM
   TI
   LI
   LO
   TS
CP0501401
 Compound Info 
(E)-3-(3'-Cyclohexylmethyl-4'-hydroxy-biphenyl-4-yl)-acrylic acid
   Show/Hide
 C22H24O3  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0509651
 Compound Info 
(E)-3-(4'-Hydroxy-[1,1';3',1'']terphenyl-4-yl)-acrylic acid
   Show/Hide
 C21H16O3  1
1
IC50 = 45300 nM
   TI
   LI
   LO
   TS
CP0515364
 Compound Info 
(E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)-N-(4-hydroxy-phenyl)-acrylamide
   Show/Hide
 C31H31NO3  1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone marrow)
Cell Line Name Organism Disease
UT-7/Epo
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
UT-7
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
KG-1
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
KG-1a
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
RS4;11
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
Rh30
 Cell Line Info 
Homo sapiens (Human) Alveolar rhabdomyosarcoma
MEG-01
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
697
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SUP-B15
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
HAP1
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
OCI-Ly1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma
OCI-Ly3
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
TMD8
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
OCI-Ly19
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
TF-1
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
L-540
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
NCI-H345
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H526
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
Z-138
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
CAL-1 [Human melanoma]
 Cell Line Info 
Homo sapiens (Human) Melanoma
SH-SY5Y
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SH-EP1
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-SH
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(2)-C
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-BE(1)
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
SK-N-AS
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
GI-CA-N
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
LSCC-HD11
 Cell Line Info 
Gallus gallus (Chicken) -
IM-9
 Cell Line Info 
Homo sapiens (Human) -
LAD 2
 Cell Line Info 
Homo sapiens (Human) -
UE6E7T-2
 Cell Line Info 
Homo sapiens (Human) -
RBC
 Cell Line Info 
Homo sapiens (Human) -
Ba/F3
 Cell Line Info 
Mus musculus (Mouse) -
FDC-P1
 Cell Line Info 
Mus musculus (Mouse) -
S21
 Cell Line Info 
Mus musculus (Mouse) -
ANA-1 [Mouse macrophage]
 Cell Line Info 
Mus musculus (Mouse) -
Y16
 Cell Line Info 
Mus musculus (Mouse) -
32D
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 FLT3-ITD
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 c-Kit D816V
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized C57BL/6
 Cell Line Info 
Mus musculus (Mouse) -
BaF3-BCL
 Cell Line Info 
Mus musculus (Mouse) -
Ba/F3 NPM-ALK
 Cell Line Info 
Mus musculus (Mouse) -
Bone marrow macrophage immortalized BALB/c
 Cell Line Info 
Mus musculus (Mouse) -