Brief Information of the Compound and Protein
Compound Name
1-[2-chloro-7-[(3S,5S)-3,5-dimethylmorpholin-4-yl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)pyridin-4-yl]urea
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PubChem ID
CID: 146680905
Canonical SMILES
C[C@H]1COC[C@H](C)N1c1c(NC(=O)Nc2ccnc(c2)C(F)(F)F)cnc2cc(Cl)nn12
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Compound Formula C19H19ClF3N7O2
Compound Structure
Protein Name
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9UDY8
Gene Name
MALT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CL000106 OCI-Ly3 Homo sapiens (Human)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM