| Compound ID |
Compound Name |
Compound Formula |
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CP0431463
|
US10272079, Compound 002
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C50H66Cl4N8O10S2
|
2
|
| 1 |
IC50 = 0.5012 nM
|
|
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| 2 |
IC50 = 5.012 nM
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CP0571696
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N-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
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C51H68Cl4N6O13S2
|
1
|
| 1 |
IC50 = 1.259 nM
|
|
|
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CP0572279
|
N,N'-bis[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]butanediamide
Show/Hide
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C48H60Cl4N6O10S2
|
1
|
| 1 |
IC50 = 1.585 nM
|
|
|
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CP0576262
|
US10272079, Compound 003
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C52H62Cl4N8O10S2
|
1
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| 1 |
IC50 = 1.585 nM
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|
|
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CP0374441
|
US10272079, Compound 67
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C58H78Cl4N8O16S2
|
1
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| 1 |
IC50 = 1.995 nM
|
|
|
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CP0434866
|
US10272079, Compound 152
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C54H66Cl4N8O12S2
|
1
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| 1 |
IC50 = 1.995 nM
|
|
|
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CP0569506
|
1-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[3-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]propyl]urea
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|
C53H72Cl4N8O12S2
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
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CP0913562
|
N1,N19-bis(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
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C68H96Cl2N16O13
|
1
|
| 1 |
IC50 = 2.63 nM
|
|
|
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CP0958976
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N1-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-N19-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-5-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
Show/Hide
|
C68H96Cl2N16O13
|
1
|
| 1 |
IC50 = 2.63 nM
|
|
|
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CP0415048
|
US10272079, Compound 115
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C52H74N8O12S2
|
1
|
| 1 |
IC50 = 2.818 nM
|
|
|
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CP0875165
|
N1,N19-bis(2-(2-(2-(2-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
Show/Hide
|
C68H96Cl2N16O13
|
1
|
| 1 |
IC50 = 2.818 nM
|
|
|
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CP0447788
|
US10272079, Compound 174
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C54H73Cl4N7O12S2
|
1
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| 1 |
IC50 = 2.951 nM
|
|
|
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CP0399536
|
US10272079, Compound 97
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C52H68Cl2N6O12S2
|
1
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| 1 |
IC50 = 3.162 nM
|
|
|
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CP0390021
|
US10272079, Compound 135
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C58H80Cl4N10O12S2
|
1
|
| 1 |
IC50 = 3.548 nM
|
|
|
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CP0389176
|
US10272079, Compound 27
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C60H78F4N12O20S2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
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CP0396065
|
US10272079, Compound 166
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C52H70Cl2F2N8O12S2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0432131
|
US10272079, Compound 30
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C58H78F4N12O16S2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0877304
|
N1,N25-bis(2-(2-(2-(2-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16,19,22-heptaoxapentacosane-1,25-diamide
Show/Hide
|
C72H104Cl2N16O15
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0573166
|
N-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
Show/Hide
|
C47H60Cl4N6O11S2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
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CP0903666
|
(S)-N,N'-(15-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-10,20-dioxo-15-(3-((2S,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)ureido)-3,6,24,27-tetraoxa-9,11,19,21-tetraazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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|
C86H120Cl6N14O21S3
|
1
|
| 1 |
IC50 = 4.266 nM
|
|
|
|
CP0546592
|
US10272079, Compound 167
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|
C86H120Cl6N14O21S3
|
1
|
| 1 |
IC50 = 4.266 nM
|
|
|
|
CP0447786
|
US10272079, Compound 146
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|
C84H117Cl6N13O18S3
|
1
|
| 1 |
IC50 = 4.467 nM
|
|
|
|
CP0415651
|
US10272079, Compound 47
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|
C58H82N8O12S2
|
2
|
| 1 |
IC50 = 4.467 nM
|
|
|
| 2 |
IC50 = 15.85 nM
|
|
|
|
CP0389173
|
US10272079, Compound 116
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|
C52H72Cl2N8O12S2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0390017
|
US10272079, Compound 6
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|
C52H68Cl4N6O14S2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0390022
|
US10272079, Compound 127
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|
C52H70Cl4N8O12S2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0415047
|
US10272079, Compound 100
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|
C60H76N6O12S2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0438104
|
US10272079, Compound 96
Show/Hide
|
C52H68Cl2N6O11S2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0914428
|
26-(carboxymethyl)-1-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-29-(25-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
Show/Hide
|
C70H98Cl2N18O20
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0491017
|
US10272079, Compound 72
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|
C62H90N8O14S2
|
2
|
| 1 |
IC50 = 5.623 nM
|
|
|
| 2 |
IC50 = 12.59 nM
|
|
|
|
CP0415652
|
US10272079, Compound 87
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|
C56H74Cl4N8O14S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0434867
|
US10272079, Compound 117
Show/Hide
|
C64H84N6O14S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0451791
|
US10272079, Compound 165
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|
C56H74Cl2F2N8O14S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
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CP0871087
|
2,2'-(methylazanediyl)bis(N-(22-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
Show/Hide
|
C65H91Cl2N17O16
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0871091
|
26-(carboxymethyl)-1-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-29-(25-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
Show/Hide
|
C78H114Cl2N22O18
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0873091
|
(S)-N,N'-(18-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-oxo-3,6,9-trioxa-12,14-diazaheptadecan-17-yl)-13,23-dioxo-3,6,9,27,30,33-hexaoxa-12,14,18,22,24-pentaazapentatriacontane-1,35-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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|
C84H117Cl6N13O18S3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0877307
|
2,2'-(methylazanediyl)bis(N-(22-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
Show/Hide
|
C73H107Cl2N21O14
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0966083
|
(S,S)-N,N'-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis(4-((1S,2S)-4,6-dichloro-2-(dimethylamino)-2,3-dihydro-1H-inden-1-yloxy)-N-methylbenzenesulfonamide)
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|
C54H74Cl4N8O12S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0848360
|
TENAPANOR HYDROCHLORIDE
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|
C50H68Cl6N8O10S2
|
2
|
| 1 |
IC50 = 6.31 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0880614
|
1-[2-[2-[2-[[4-[(1S,2S)-6-chloro-4-fluoro-2-[(3R)-3-hydroxypyrrolidin-1-yl]indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[4-[(1S,2S)-4,6-dichloro-2-[(3R)-3-hydroxypyrrolidin-1-yl]indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
Show/Hide
|
C56H74Cl3FN8O14S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
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CP0956949
|
1-[2-[2-[2-[[4-[(1S,2S)-4,6-dichloro-2-(dimethylamino)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[[[4-[(1S,2S)-4,6-dichloro-2-(dimethylamino)indan-1-yl]oxyphenyl]sulfonyl-methyl-amino]methoxy]ethoxy]ethylcarbamoylamino]butyl]urea
Show/Hide
|
C52H70Cl4N8O12S2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0431669
|
US10272079, Compound 164
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|
C79H101Cl6N11O18S3
|
1
|
| 1 |
IC50 = 7.413 nM
|
|
|
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CP0864397
|
(S)-N,N'-(15-amino-15-(1-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-10,20-dioxo-3,6,24,27-tetraoxa-9,11,19,21-tetraazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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|
C79H107Cl6N13O15S3
|
1
|
| 1 |
IC50 = 7.413 nM
|
|
|
|
CP0554452
|
US10272079, Compound 168
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|
C76H101Cl6N13O15S3
|
1
|
| 1 |
IC50 = 7.413 nM
|
|
|
|
CP0386639
|
US10272079, Compound 109
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|
C79H108Cl6N13O15S3+
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
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CP0396066
|
US10272079, Compound 173
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|
C78H101Cl6N9O16S3
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0404361
|
US10272079, Compound 29
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|
C56H74F4N12O16S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0411224
|
US10272079, Compound 118
Show/Hide
|
C64H84N6O14S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0427529
|
US10272079, Compound 101
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|
C60H76N6O12S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0497760
|
US10272079, Compound 98
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|
C56H76N6O14S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0497762
|
US10272079, Compound 107
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|
C81H111Cl6N13O15S3
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
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CP0875557
|
1-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[4-[2-[2-[2-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]ethoxy]ethoxy]ethyl]urea
Show/Hide
|
C70H102Cl2N22O12
|
1
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| 1 |
IC50 = 7.943 nM
|
|
|
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CP0864398
|
(S)-N,N'-(2,2'-(2,2'-(2,2'-(1,4-phenylenebis(azanediyl))bis(oxomethylene)bis(azanediyl)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)dihydrochloride
Show/Hide
|
C52H64Cl6N8O10S2
|
2
|
| 1 |
IC50 = 7.943 nM
|
|
|
| 2 |
IC50 = 10 nM
|
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CP0900164
|
3-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-1-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoyl-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoyl-methyl-amino]propyl]amino]propyl]-1-methyl-urea
Show/Hide
|
C77H102Cl6N12O15S3
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
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CP0903014
|
1-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethyl]-3-[2-[2-[[4-[2-[2-[2-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]methoxy]ethoxy]ethyl]urea
Show/Hide
|
C69H100Cl2N22O12
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
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CP0545458
|
N-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetamide
Show/Hide
|
C48H60Cl4N6O11S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
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CP0568623
|
1,3-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]urea
Show/Hide
|
C49H64Cl4N6O11S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
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CP0387134
|
US10272079, Compound 149
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C50H64Cl4N6O13S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0458736
|
US10272079, Compound 150
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C50H64Cl4N6O14S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0548233
|
US10272079, Compound 128
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|
C80H105Cl6N11O16S3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0851375
|
3,12-bis(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-N1,N14-bis(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-diamide
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|
C110H148Cl8N14O26S4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0867115
|
1-[2-[2-[2-[2-[4-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[4-[2-[2-[2-[2-[2-[2-[2-[4-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]ethoxy]ethoxy]ethyl]urea
Show/Hide
|
C66H94Cl2N18O16
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0415046
|
US10272079, Compound 48
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|
C62H86N8O16S2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 79.43 nM
|
|
|
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CP0415653
|
US10272079, Compound 88
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|
C76H98Cl6N10O15S3
|
1
|
| 1 |
IC50 = 11.75 nM
|
|
|
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CP0390024
|
US10272079, Compound 81
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|
C54H70Cl4N8O14S2
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
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CP0446372
|
US10272079, Compound 155
Show/Hide
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C83H111Cl6N13O18S3
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1
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| 1 |
IC50 = 12.59 nM
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CP0510136
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US10272079, Compound 89
Show/Hide
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C85H114Cl6N10O19S3
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1
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| 1 |
IC50 = 12.59 nM
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CP0845574
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(2R,3R)-2,3-dihydroxy-N1,N4-bis(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)succinamide
Show/Hide
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C60H84N6O16S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0848305
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(S)-N,N'-(15-(2-(3-((S)-5,7-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)phenylsulfonyl)-12-oxo-5,8-dioxa-2,11,13-triazahexadecan-16-yl)-10,20-dioxo-3,6,24,27-tetraoxa-9,11,15,19,21-pentaazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-methylbenzenesulfonamide)
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C81H111Cl6N13O15S3
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1
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| 1 |
IC50 = 12.59 nM
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CP0872738
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2-[2-[carboxymethyl-[2-[2-[2-[2-[2-[2-[2-[2-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]amino]ethyl-[2-[2-[2-[2-[2-[2-[2-[2-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]amino]acetic acid
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C70H98Cl2N18O20
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1
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| 1 |
IC50 = 12.59 nM
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CP0873089
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26-(carboxymethyl)-1-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-29-(25-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
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C78H114Cl2N22O18
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1
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| 1 |
IC50 = 12.59 nM
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CP0875556
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(E)-N-(diaminomethylene)-3-(4-(4-(N-(1-(4-(4-((E)-3-(diaminomethyleneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluorophenoxy)phenylsulfonamido)-13,17-dioxo-3,6,9,15,21,25,28-heptaoxa-12,18-diazatriacontan-30-yl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylamide
Show/Hide
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C55H70F4N10O17S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0877308
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2,2'-(methylazanediyl)bis(N-(19-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecyl)acetamide)
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C69H99Cl2N21O12
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1
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| 1 |
IC50 = 12.59 nM
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CP0911853
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2,2'-(methylazanediyl)bis(N-(22-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
Show/Hide
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C73H107Cl2N21O14
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1
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| 1 |
IC50 = 12.59 nM
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CP0434880
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US10272079, Compound 15
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C54H68F4N10O17S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0487225
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US10272079, Compound 106
Show/Hide
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C81H111Cl6N13O15S3
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1
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| 1 |
IC50 = 12.59 nM
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CP0852587
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1-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
Show/Hide
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C62H90N8O14S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0945610
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2,3-dihydroxy-N,N'-bis[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]butanediamide
Show/Hide
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C60H84N6O16S2
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1
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| 1 |
IC50 = 12.59 nM
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CP0389179
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US10272079, Compound 5
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C54H68F4N10O18S2
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1
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| 1 |
IC50 = 14.13 nM
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CP0477877
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US10272079, Compound 90
Show/Hide
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C82H110Cl6N10O18S3
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1
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| 1 |
IC50 = 14.13 nM
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CP0379929
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US10272079, Compound 119
Show/Hide
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C61H86N6O14S2
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1
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| 1 |
IC50 = 15.85 nM
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CP0431403
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US10272079, Compound 16
Show/Hide
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C25H33ClN8O2
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1
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| 1 |
IC50 = 15.85 nM
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CP0431462
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US10272079, Compound 177
Show/Hide
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C83H108Cl6N10O19S3
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1
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| 1 |
IC50 = 15.85 nM
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CP0432134
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US10272079, Compound 61
Show/Hide
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C78H101Cl6N9O19S3
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1
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| 1 |
IC50 = 15.85 nM
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CP0440461
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US10272079, Compound 139
Show/Hide
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C80H102Cl6N10O19S3
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1
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| 1 |
IC50 = 15.85 nM
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CP0467846
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US10272079, Compound 148
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C50H64Cl4N6O12S2
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1
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| 1 |
IC50 = 15.85 nM
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CP0470943
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US10272079, Compound 123
Show/Hide
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C80H102Cl6N10O18S3
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1
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| 1 |
IC50 = 15.85 nM
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CP0911854
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4-[[4-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-1-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-1-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]-4-oxo-butyl]amino]-4-oxo-butanoic acid
Show/Hide
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C79H100Cl6N10O18S3
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1
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| 1 |
IC50 = 15.85 nM
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CP0954102
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1-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
Show/Hide
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C58H82N8O12S2
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1
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| 1 |
IC50 = 15.85 nM
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CP0404353
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US10272079, Compound 179
Show/Hide
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C58H77Cl4N7O15S2
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1
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| 1 |
IC50 = 16.98 nM
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CP0404355
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US10272079, Compound 144
Show/Hide
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C83H110Cl6N12O17S3
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1
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| 1 |
IC50 = 16.98 nM
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CP0415051
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US10272079, Compound 157
Show/Hide
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C79H103Cl6N11O19S4
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1
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| 1 |
IC50 = 16.98 nM
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CP0411218
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US10272079, Compound 31
Show/Hide
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C56H72F4N12O16S2
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1
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| 1 |
IC50 = 19.95 nM
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CP0415053
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US10272079, Compound 160
Show/Hide
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C58H78Cl2F2N8O12S2
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1
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| 1 |
IC50 = 19.95 nM
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CP0420506
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US10272079, Compound 132
Show/Hide
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C84H117Cl6N13O15S3
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1
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| 1 |
IC50 = 19.95 nM
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CP0427000
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US10272079, Compound 140
Show/Hide
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C58H80F2N8O12S2
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1
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| 1 |
IC50 = 19.95 nM
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CP0434987
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US10272079, Compound 84
Show/Hide
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C78H101Cl6N9O18S3
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1
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| 1 |
IC50 = 19.95 nM
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CP0471224
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US10272079, Compound 136
Show/Hide
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C52H72F2N8O12S2
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1
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| 1 |
IC50 = 19.95 nM
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CP0490143
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US10272079, Compound 26
Show/Hide
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C58H76F4N10O20S2
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1
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| 1 |
IC50 = 19.95 nM
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CP0864961
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(S)-2-(3-(1,25-bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-10,16-dioxo-3,6,20,23-tetraoxa-9,17-diazapentacosan-13-yl)ureido)succinic acid
Show/Hide
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C81H103Cl6N11O20S3
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1
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| 1 |
IC50 = 19.95 nM
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CP0913933
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2,2'-(methylazanediyl)bis(N-(22-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
Show/Hide
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C65H91Cl2N17O16
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1
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| 1 |
IC50 = 19.95 nM
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CP0390020
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US10272079, Compound 147
Show/Hide
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C79H107Cl6N13O15S3
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1
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| 1 |
IC50 = 21.38 nM
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CP0389073
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US10272079, Compound 14
Show/Hide
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C58H78F4N12O18S2
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1
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| 1 |
IC50 = 25.12 nM
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CP0415054
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US10272079, Compound 163
Show/Hide
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C80H103Cl6N11O19S3
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1
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| 1 |
IC50 = 25.12 nM
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CP0434864
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US10272079, Compound 161
Show/Hide
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C83H111Cl6N13O19S3
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1
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| 1 |
IC50 = 25.12 nM
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CP0494901
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US10272079, Compound 50
Show/Hide
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C57H79N7O12S2
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1
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| 1 |
IC50 = 25.12 nM
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CP0877306
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2-[methyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]-N-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]acetamide
Show/Hide
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C57H79N7O12S2
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1
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| 1 |
IC50 = 25.12 nM
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CP0390018
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US10272079, Compound 001
Show/Hide
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C22H26Cl2N2O6
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2
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| 1 |
IC50 = 25.12 nM
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| 2 |
IC50 = 39.81 nM
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CP0387135
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US10272079, Compound 151
Show/Hide
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C51H66Cl4N6O12S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0404359
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US10272079, Compound 57
Show/Hide
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C78H102Cl6N10O18S3
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1
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| 1 |
IC50 = 31.62 nM
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CP0434861
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US10272079, Compound 10
Show/Hide
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C21H25ClN6O3
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1
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| 1 |
IC50 = 31.62 nM
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CP0434877
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US10272079, Compound 37
Show/Hide
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C23H29ClN6O4
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1
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| 1 |
IC50 = 31.62 nM
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CP0861099
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N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(dimethylamino)heptanediamide
Show/Hide
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C78H102Cl6N10O15S3
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1
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| 1 |
IC50 = 31.62 nM
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CP0867116
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N1,N19-bis(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
Show/Hide
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C66H96N6O17S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0883781
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N1-(2-(2-(2-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-N7-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(4-methylpiperazine-1-carboxamido)heptanediamide
Show/Hide
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C82H108Cl6N12O16S3
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1
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| 1 |
IC50 = 31.62 nM
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CP0434865
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US10272079, Compound 153
Show/Hide
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C82H108Cl6N12O16S3
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1
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| 1 |
IC50 = 31.62 nM
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CP0900166
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3-[2-[2-[2-[2-[3-oxo-3-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]propoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
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C66H96N6O17S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0562995
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N-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-2-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetamide
Show/Hide
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C48H60Cl4N6O11S2
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1
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| 1 |
IC50 = 31.62 nM
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CP0409699
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US10272079, Compound 176
Show/Hide
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C83H111Cl6N11O16S3
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1
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| 1 |
IC50 = 39.81 nM
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CP0425002
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US10272079, Compound 19
Show/Hide
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C25H33ClN8O2
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1
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| 1 |
IC50 = 39.81 nM
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CP0425257
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(2R,3S,4R,5R)-N-[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]-2,3,4,5,6-pentahydroxyhexanamide
Show/Hide
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C22H26Cl2N2O6
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2
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| 1 |
IC50 = 39.81 nM
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| 2 |
IC50 = 50.12 nM
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CP0471883
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US10272079, Compound 13
Show/Hide
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C58H72F4N10O14S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0546591
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US10272079, Compound 175
Show/Hide
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C79H104Cl6N10O15S3
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1
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| 1 |
IC50 = 39.81 nM
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CP0864960
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(1S,2S)-2-(1,25-bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-10,16-dioxo-3,6,20,23-tetraoxa-9,17-diazapentacosan-13-ylcarbamoyl)cyclohexanecarboxylic acid
Show/Hide
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C84H108Cl6N10O18S3
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1
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| 1 |
IC50 = 39.81 nM
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CP0873090
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6-(carboxymethyl)-8-oxo-3-(2-oxo-14-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)-6,9,12-trioxa-3-azatetradecyl)-20-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)-12,15,18-trioxa-3,6,9-triazaicosan-1-oic acid
Show/Hide
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C66H94N8O18S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0875560
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N1,N19-bis(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
Show/Hide
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C70H104N6O19S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0913934
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2,2'-(methylazanediyl)bis(N-(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
Show/Hide
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C61H87N7O14S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0857135
|
2-[2-[carboxymethyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]ethyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]acetic acid
Show/Hide
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C66H94N8O18S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0857138
|
(1S,2S)-2-[[1,1-bis[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]-4-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethylamino]-4-oxo-butyl]carbamoyl]cyclohexanecarboxylic acid
Show/Hide
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C82H104Cl6N10O17S3
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1
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| 1 |
IC50 = 39.81 nM
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CP0900165
|
2-[methyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]-N-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]acetamide
Show/Hide
|
C61H87N7O14S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0900167
|
3-[2-[2-[2-[2-[3-oxo-3-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]propoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
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C70H104N6O19S2
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1
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| 1 |
IC50 = 39.81 nM
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CP0550395
|
N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)terephthalamide
Show/Hide
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C56H68Cl4N6O12S2
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1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0569571
|
N,N′-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,14,19,21-tetraazadotriacontane-1,32-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
Show/Hide
|
C54H74Cl4N8O12S2
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0434873
|
US10272079, Compound 77
Show/Hide
|
C78H105Cl6N13O15S3
|
1
|
| 1 |
IC50 = 44.67 nM
|
|
|
|
CP0415055
|
US10272079, Compound 178
Show/Hide
|
C80H105Cl6N11O18S3
|
1
|
| 1 |
IC50 = 46.77 nM
|
|
|
|
CP0415052
|
US10272079, Compound 159
Show/Hide
|
C81H106Cl6N12O18S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0425260
|
US10272079, Compound 59
Show/Hide
|
C81H111Cl6N13O18S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0425274
|
US10272079, Compound 58
Show/Hide
|
C112H152Cl8N16O24S4
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0447784
|
US10272079, Compound 133
Show/Hide
|
C77H99Cl6N11O16S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0447785
|
US10272079, Compound 137
Show/Hide
|
C81H104Cl6N10O18S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0458732
|
US10272079, Compound 138
Show/Hide
|
C81H105Cl6N11O18S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0849850
|
1-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea Dihydrochloride
Show/Hide
|
C50H68Cl6N8O10S2
|
2
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 = 2511.89 nM
|
|
|
|
CP0911880
|
2-[4,10-bis[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-7-[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-1,4,7,10-tetrazacyclododec-1-yl]-N-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]acetamide
Show/Hide
|
C109H146Cl8N16O23S4
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0945613
|
1-[2-[bis[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]amino]ethyl]-3-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]urea
Show/Hide
|
C81H111Cl6N13O18S3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0571697
|
N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)terephthalamide
Show/Hide
|
C56H68Cl4N6O12S2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0440489
|
US10272079, Compound 143
Show/Hide
|
C83H111Cl6N11O21S3
|
1
|
| 1 |
IC50 = 53.7 nM
|
|
|
|
CP0374440
|
US10272079, Compound 62
Show/Hide
|
C26H35Cl2N3O5S
|
1
|
| 1 |
IC50 = 56.23 nM
|
|
|
|
CP0411258
|
US10272079, Compound 7
Show/Hide
|
C21H26ClN7O4S
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0432126
|
US10272079, Compound 20
Show/Hide
|
C62H86Cl2N18O10
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0467845
|
US10272079, Compound 130
Show/Hide
|
C78H101Cl6N11O16S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0467849
|
US10272079, Compound 70
Show/Hide
|
C96H135Cl6N21O18S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0864448
|
3,3',3''-nitrilotris(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)propanamide)
Show/Hide
|
C81H108Cl6N10O18S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0869154
|
(S)-N,N'-(15-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-9-methyl-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-9,21-dimethyl-10,20-dioxo-3,6,24,27-tetraoxa-9,11,15,19,21-pentaazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
Show/Hide
|
C81H111Cl6N13O15S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0883790
|
N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(4-(2-(2-hydroxyethoxy)ethyl)piperazine-1-carboxamido)heptanediamide
Show/Hide
|
C85H114Cl6N12O18S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0885290
|
4-(2-(1H-tetrazol-5-yl)acetamido)-N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)heptanediamide
Show/Hide
|
C79H100Cl6N14O16S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0880615
|
N,N'-bis[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-4-[3-[2-[2-[2-[[4-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]propyl]-4-[[4-[2-(2-hydroxyethoxy)ethyl]piperazine-1-carbonyl]amino]heptanediamide
Show/Hide
|
C85H116Cl6N12O17S3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0468429
|
N,N'-bis[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]butanediamide
Show/Hide
|
C48H60Cl4N6O10S2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0529374
|
N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
Show/Hide
|
C49H64Cl4N6O11S2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0579777
|
N-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
Show/Hide
|
C47H60Cl4N6O11S2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0415045
|
US10272079, Compound 60
Show/Hide
|
C26H37N3O5S
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0415049
|
US10272079, Compound 142
Show/Hide
|
C84H113Cl6N11O21S3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0467848
|
US10272079, Compound 172
Show/Hide
|
C80H105Cl6N13O19S3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0871220
|
N1,N1,N19,N19-tetrakis(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
Show/Hide
|
C114H156Cl8N18O27S4
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0875164
|
N-(diaminomethylene)-3-[4-[4-[2-[2-[2-[2-[[2-[[2-[2-[2-[2-[2-[[4-[2,6-difluoro-4-[3-guanidino-2-methyl-3-oxo-prop-1-enyl]phenoxy]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-methyl-amino]acetyl]amino]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]phenoxy]-3,5-difluoro-phenyl]-2-methyl-prop-2-enamide
Show/Hide
|
C55H71F4N11O16S2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0860425
|
4-[2-[2-[2-[3-[bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]amino]-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]-N,N-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]butanamide
Show/Hide
|
C113H154Cl8N18O26S4
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0872737
|
2-[2-[carboxymethyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]ethyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]acetic acid
Show/Hide
|
C62H86N8O16S2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0911879
|
N-(diaminomethylene)-3-[4-[4-[2-[2-[2-[2-[[2-[[2-[2-[2-[2-[2-[[4-[2,6-difluoro-4-[3-guanidino-2-methyl-3-oxo-prop-1-enyl]phenoxy]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-methyl-amino]acetyl]amino]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]phenoxy]-3,5-difluoro-phenyl]-2-methyl-prop-2-enamide
Show/Hide
|
C55H71F4N11O16S2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0569542
|
N-[2-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
Show/Hide
|
C51H68Cl4N6O13S2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0434882
|
US10272079, Compound 12
Show/Hide
|
C23H30ClN7O5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0487224
|
US10272079, Compound 56
Show/Hide
|
C81H99Cl6N9O18S3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0915642
|
N1,N1,N31,N31-tetrakis(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-diamide
Show/Hide
|
C122H172Cl8N18O31S4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0916649
|
2,2'-((1R,2R)-2-(1-(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-3-(2-(2-(2-(2-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)ureido)cyclohexylazanediyl)bis(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
Show/Hide
|
C109H144Cl8N14O24S4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0947280
|
2,2'-(methylazanediyl)bis(N-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
Show/Hide
|
C59H79Cl2N17O8
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0434884
|
US10272079, Compound 71
Show/Hide
|
C109H144Cl8N14O24S4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952974
|
2-((14-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-2-oxo-6,9,12-trioxa-3-azatetradecyl)(methyl)amino)-N-(2-(2-(3-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-5-yl)phenyl)piperazin-1-yl)ethoxy)propoxy)ethoxy)ethyl)acetamide
Show/Hide
|
C60H81Cl2N17O8
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0573164
|
2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]acetic acid
Show/Hide
|
C18H18Cl2N2O4S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0431405
|
US10272079, Compound 22
Show/Hide
|
C24H33Cl2N3O5S
|
2
|
| 1 |
IC50 = 112.2 nM
|
|
|
| 2 |
IC50 = 501.19 nM
|
|
|
|
CP0434872
|
US10272079, Compound 80
Show/Hide
|
C75H96Cl6N10O15S3
|
1
|
| 1 |
IC50 = 117.49 nM
|
|
|
|
CP0389072
|
US10272079, Compound 18
Show/Hide
|
C27H37ClN8O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0404354
|
US10272079, Compound 158
Show/Hide
|
C81H107Cl6N11O19S3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0420504
|
US10272079, Compound 129
Show/Hide
|
C79H103Cl6N11O16S3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0888102
|
2,2'-(20-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-3,6-bis(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-8-oxo-12,15,18-trioxa-3,6,9-triazaicosylazanediyl)bis(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
Show/Hide
|
C134H178Cl10N18O30S5
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0536231
|
US10272079, Compound 75
Show/Hide
|
C134H178Cl10N18O30S5
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0374426
|
US10272079, Compound 122
Show/Hide
|
C77H100Cl6N10O17S4
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0389178
|
US10272079, Compound 11
Show/Hide
|
C21H25ClN6O3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0404352
|
US10272079, Compound 4
Show/Hide
|
C25H33F2N5O7S
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0415050
|
US10272079, Compound 154
Show/Hide
|
C81H102Cl6N12O16S3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0444143
|
US10272079, Compound 74
Show/Hide
|
C72H90Cl6N10O15S3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0550397
|
N-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
Show/Hide
|
C51H68Cl4N6O13S2
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0420760
|
US10272079, Compound 69
Show/Hide
|
C93H126Cl6N18O18S3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0571350
|
N-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
Show/Hide
|
C51H68Cl4N6O13S2
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0572958
|
N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
Show/Hide
|
C49H64Cl4N6O11S2
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0446392
|
US10272079, Compound 17
Show/Hide
|
C54H68Cl2N16O8
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0875166
|
(S)-N-(2-(2-(2-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)ethoxy)ethoxy)ethyl)-2-(14-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyloxy)acetamide
Show/Hide
|
C49H60Cl3N9O11S
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0883789
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17-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-5,5-bis(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-3,8-dioxo-12,15-dioxa-2,4,9-triazaheptadecylphosphonic acid
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C78H102Cl6N11O19PS3
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1
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| 1 |
IC50 = 251.19 nM
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CP0389071
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US10272079, Compound 25
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C49H60Cl3N9O11S
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1
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| 1 |
IC50 = 251.19 nM
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CP0431668
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US10272079, Compound 162
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C79H105Cl6N12O19PS3
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1
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| 1 |
IC50 = 251.19 nM
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CP0446364
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US10272079, Compound 126
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C60H84N10O10
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1
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| 1 |
IC50 = 281.84 nM
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CP0380071
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US10272079, Compound 78
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C72H89Cl6N9O16S3
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1
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| 1 |
IC50 = 316.23 nM
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CP0411800
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US10272079, Compound 134
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C78H102Cl6N10O15S3
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1
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| 1 |
IC50 = 316.23 nM
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CP0420758
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US10272079, Compound 2
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C19H22Cl2N2O3S
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1
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| 1 |
IC50 = 316.23 nM
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CP0866811
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3-[bis[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonyl-methyl-amino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]amino]-N-[2-[2-[2-[[4-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonyl-methyl-amino]ethoxy]ethoxy]ethyl]propanamide
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C78H102Cl6N10O15S3
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1
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| 1 |
IC50 = 316.23 nM
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CP0573234
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N-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethyl]-3-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethylamino]-2,3-dihydroxypropanamide
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C43H52Cl4N6O9S2
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1
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| 1 |
IC50 = 316.23 nM
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CP0374444
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US10272079, Compound 76
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C75H99Cl6N13O15S3
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1
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| 1 |
IC50 = 398.11 nM
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CP0432124
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US10272079, Compound 8
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C21H26ClN7O4S
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1
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| 1 |
IC50 = 398.11 nM
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CP0380550
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US10272079, Compound 73
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C81H102Cl6N16O15S3
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1
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| 1 |
IC50 = 501.19 nM
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CP0446394
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US10272079, Compound 169
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C78H99Cl6N9O16S3
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1
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| 1 |
IC50 = 630.96 nM
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CP0958975
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1-[3,3-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]-4-oxo-pentyl]-3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]urea
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C78H102Cl6N12O16S3
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1
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| 1 |
IC50 = 630.96 nM
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CP0434883
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US10272079, Compound 1
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C16H16Cl2N2O2S
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1
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| 1 |
IC50 = 630.96 nM
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CP0497758
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US10272079, Compound 85
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C102H132Cl8N14O22S4
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1
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| 1 |
IC50 = 794.33 nM
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CP0569106
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N-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethyl]-3-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethylamino]-2,3-dihydroxypropanamide
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C39H44Cl4N6O7S2
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1
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| 1 |
IC50 = 1000 nM
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CP0913565
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(S)-N,N'-(14-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-14-(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-10,15-dioxo-3,6-dioxa-9,11,14,16-tetraazaoctacosan-28-ylcarbamoyl)-10,18-dioxo-3,6,22,25-tetraoxa-9,11,14,17,19-pentaazaheptacosane-1,27-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C114H158Cl8N20O22S4
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1
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| 1 |
IC50 = 1258.93 nM
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CP0572302
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3-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]propane-1-sulfonic acid
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C19H22Cl2N2O5S2
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1
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| 1 |
IC50 = 1584.89 nM
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CP0572956
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N,N′-(10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecane-1,19-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C45H56Cl4N6O9S2
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1
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| 1 |
IC50 = 1995.26 nM
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CP0406309
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US10272079, Compound 38
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C20H24N2O3S
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1
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| 1 |
IC50 = 2511.89 nM
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CP0477878
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US10272079, Compound 94
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C87H118Cl6N10O16S3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0863055
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(R)-N,N'-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)dihydrochloride
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C50H68Cl6N8O10S2
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1
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| 1 |
IC50 = 2511.89 nM
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CP0957148
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4-[2-(1-piperidyl)indan-1-yl]oxybenzenesulfonamide
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C20H24N2O3S
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1
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| 1 |
IC50 = 2511.89 nM
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CP0572270
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US10272079, Compound 3
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C22H26Cl2N2O6
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1
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| 1 |
IC50 = 2511.89 nM
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CP0550392
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3-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]propylphosphonic acid
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C19H23Cl2N2O5PS
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1
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| 1 |
IC50 = 5011.87 nM
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CP0573165
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3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)-N-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]benzenesulfonamide
Show/Hide
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C38H42Cl4N4O6S2
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1
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| 1 |
IC50 = 5011.87 nM
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CP0379944
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US10272079, Compound 68
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C58H78Cl4N8O12S2
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1
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| 1 |
IC50 > 10000 nM
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CP0380073
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US10272079, Compound 113
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C89H107Cl7N10O15S3
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1
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| 1 |
IC50 > 10000 nM
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CP0389074
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US10272079, Compound 91
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C95H117Cl7N10O19S3
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1
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| 1 |
IC50 > 10000 nM
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CP0404358
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US10272079, Compound 99
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C56H78N8O12S2
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1
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| 1 |
IC50 = 10000 nM
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CP0415043
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US10272079, Compound 004
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C50H66Cl4N8O10S2
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1
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| 1 |
IC50 > 10000 nM
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CP0431400
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US10272079, Compound 83
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C112H152Cl8N18O22S4
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1
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| 1 |
IC50 > 10000 nM
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CP0941818
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4-((4'-chlorobiphenyl-4-yl)methylamino)-4-(1-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-oxo-3,6,9-trioxa-12-azapentadecan-15-yl)-N1,N7-bis(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)heptanediamide
Show/Hide
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C95H119Cl7N10O18S3
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1
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| 1 |
IC50 > 10000 nM
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CP0559117
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US10272079, Compound 114
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C95H119Cl7N10O18S3
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1
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| 1 |
IC50 > 10000 nM
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CP0902826
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1-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea Dihydrochloride
Show/Hide
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C50H68Cl6N8O10S2
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1
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| 1 |
IC50 > 10000 nM
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CP0550393
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N-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
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C51H68Cl4N6O13S2
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1
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| 1 |
IC50 > 31622.78 nM
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CP0466743
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N,N′-(10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecane-1,19-diyl)bis(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C45H56Cl4N6O9S2
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1
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| 1 |
IC50 > 3162.28 nM
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CP0550394
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N1,N4-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)terephthalamide
Show/Hide
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C52H60Cl4N6O10S2
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1
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| 1 |
IC50 > 3162.28 nM
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CP0565542
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N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)terephthalamide
Show/Hide
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C52H60Cl4N6O10S2
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1
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| 1 |
IC50 > 3162.28 nM
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