| Compound ID |
Compound Name |
Compound Formula |
|
CP0459720
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-1-benzyl-6-chloroquinolin-2(1H)-one
Show/Hide
|
C29H28ClN3O3
|
2
|
| 1 |
IC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0439546
|
6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)-1-(pyridin-2-ylmethyl)quinolin-2(1H)-one
Show/Hide
|
C31H29ClN4O
|
2
|
| 1 |
IC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 55 nM
|
|
|
|
CP0045213
|
7-fluoro-4-oxo-N-(1-((2-oxo-2H-chromen-7-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
|
C25H21FN2O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0382429
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-(pyridin-4-ylmethyl)quinolin-2(1H)-one
Show/Hide
|
C28H27ClN4O3
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0459724
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-(pyridin-2-ylmethyl)quinolin-2(1H)-one
Show/Hide
|
C28H27ClN4O3
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0059470
|
2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-6-yl)acetamide
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|
C28H30N4O2
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0339653
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-chloro-3-methyl-4-oxochromene-2-carboxamide
Show/Hide
|
C24H23ClN2O5
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
|
CP0352046
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6,7-difluoro-4-oxochromene-2-carboxamide
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|
C23H20F2N2O5
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 13 nM
|
|
|
|
CP0352047
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-7-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C24H23FN2O6
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0442415
|
N-[1-[[2-chloro-4-(2-pyrrolidin-1-ylethylcarbamoyl)phenyl]methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C29H32ClFN4O4
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 136 nM
|
|
|
|
CP0408093
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(1,3-thiazol-2-ylmethylamino)benzamide
Show/Hide
|
C24H25ClN4O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0184032
|
4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylamino)-6-chloro-chromen-2-one
Show/Hide
|
C22H21ClN2O4
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0439494
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one
Show/Hide
|
C23H22ClF3N4O3
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0045218
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H21FN2O5
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0077798
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-chloro-6-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20ClFN2O5
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 71 nM
|
|
|
|
CP0280205
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6,7-dichloro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20Cl2N2O5
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 83 nM
|
|
|
|
CP0526888
|
7-fluoro-N-(1-((1-methyl-2-oxo-1,2-dihydroquinolin-7-yl)methyl)piperidin-4-yl)-4-oxo-4H-chromene-2-carboxamide
Show/Hide
|
C26H24FN3O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0430633
|
N-[3-(2-aminoquinolin-8-yl)oxypropyl]-3-chlorobenzamide
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|
C19H18ClN3O2
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0444878
|
7-fluoro-N-[1-[[3-fluoro-4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C30H35F2N3O4
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 86 nM
|
|
|
|
CP0436213
|
4-(1-Benzooxazol-5-ylmethyl-piperidin-4-ylamino)-6-chloro-chromen-2-one
Show/Hide
|
C22H20ClN3O3
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 163 nM
|
|
|
|
CP0459734
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-methoxy-1-methylquinolin-2(1H)-one
Show/Hide
|
C24H27N3O4
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0442648
|
N-[1-(1-benzothiophen-5-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C24H21FN2O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0881251
|
N-(1-(4-(3-(2,4-dioxothiazolidin-3-yl)propoxy)-3-fluorobenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide
Show/Hide
|
C28H27F2N3O6S
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 545 nM
|
|
|
|
CP0438996
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(1,3-thiazol-4-ylmethylamino)pyridine-3-carboxamide
Show/Hide
|
C23H24ClN5O3S
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0911590
|
6-Methoxy-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C24H26N2O3
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 44 nM
|
|
|
|
CP0425169
|
4-(8-(benzo[d][1,3]dioxol-5-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ylamino)-6-chloro-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one
Show/Hide
|
C25H24ClF3N4O3
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0522985
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloroquinolin-2(1H)-one
Show/Hide
|
C22H22ClN3O3
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 26 nM
|
|
|
|
CP0352044
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-chloro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H21ClN2O5
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 79 nM
|
|
|
|
CP0502750
|
7-fluoro-N-[1-(1H-indol-6-ylmethyl)piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C24H22FN3O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0407899
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-1-benzyl-5-nitroindazol-3-amine
Show/Hide
|
C27H27N5O4
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 350 nM
|
|
|
|
CP0425170
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-(difluoromethoxy)-1-methylquinolin-2(1H)-one
Show/Hide
|
C24H25F2N3O4
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0442397
|
6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one
Show/Hide
|
C26H24ClF3N4O
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
|
CP0459725
|
6-chloro-1-methyl-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)quinolin-2(1H)-one
Show/Hide
|
C26H26ClN3O
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0527082
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-methylquinazolin-2(1H)-one
Show/Hide
|
C22H23ClN4O3
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
|
CP0495198
|
5-Chloro-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl)-2-[(thiazol-2-ylmethyl)-amino]-benzamide
Show/Hide
|
C27H27ClN4OS
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0495202
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(1,3-thiazol-2-ylmethylamino)pyridine-3-carboxamide
Show/Hide
|
C23H24ClN5O3S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0483705
|
4-(1-Benzo[b]thiophen-5-ylmethyl-piperidin-4-ylamino)-6-chloro-chromen-2-one
Show/Hide
|
C23H21ClN2O2S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 189 nM
|
|
|
|
CP0442382
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-nitro-1H-indazol-3-amine
Show/Hide
|
C20H21N5O4
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0442649
|
7-fluoro-4-oxo-N-(1-((2-oxo-1,2-dihydroquinolin-7-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
|
C25H22FN3O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0526123
|
N-[1-(1-benzofuran-5-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C24H21FN2O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0406586
|
N-[3-(2-aminoquinolin-8-yl)oxypropyl]-3-cyanobenzamide
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0495203
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(3-propan-2-yloxypropylamino)pyridine-3-carboxamide
Show/Hide
|
C25H33ClN4O4
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0442133
|
6-Chloro-4-[1-(1H-indol-5-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C23H22ClN3O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 63 nM
|
|
|
|
CP0562480
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-1-(pyridin-4-ylmethyl)indazol-3-amine
Show/Hide
|
C26H26ClN5O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 560 nM
|
|
|
|
CP0522986
|
6-chloro-1-methyl-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)quinazolin-2(1H)-one
Show/Hide
|
C25H25ClN4O
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 72 nM
|
|
|
|
CP0491959
|
1-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-(3-chloro-phenyl)-urea
Show/Hide
|
C19H19ClN4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0407896
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-1H-indazol-3-amine
Show/Hide
|
C21H24N4O3
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0431287
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-2-(pyrimidin-5-ylmethylamino)benzamide
Show/Hide
|
C26H29N5O4
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0484106
|
2-Amino-N-(1-benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-benzamide
Show/Hide
|
C20H22ClN3O3
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0495201
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(1H-imidazol-5-ylmethylamino)pyridine-3-carboxamide
Show/Hide
|
C23H25ClN6O3
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0378903
|
6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C23H23ClN2O2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 211 nM
|
|
|
|
CP0378010
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-1-(pyridin-2-ylmethyl)indazol-3-amine
Show/Hide
|
C26H26ClN5O2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 550 nM
|
|
|
|
CP0442720
|
N-[1-(1,3-benzoxazol-6-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20FN3O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0494620
|
N-[3-[2-[[5-(3-chlorophenyl)furan-2-yl]methylamino]quinolin-8-yl]oxypropyl]-3-cyanobenzamide
Show/Hide
|
C31H25ClN4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0403380
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(cyclopropylmethylamino)-5-methoxybenzamide
Show/Hide
|
C25H31N3O4
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
|
CP0408066
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(2-propan-2-yloxyethylamino)pyridine-3-carboxamide
Show/Hide
|
C24H31ClN4O4
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0502748
|
N-(1-benzylpiperidin-4-yl)-5-chloro-2-[(4-methoxyphenyl)methylamino]pyridine-3-carboxamide
Show/Hide
|
C26H29ClN4O2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0515862
|
N-[1-[(4-acetylphenyl)methyl]piperidin-4-yl]-5-chloro-2-(1H-imidazol-5-ylmethylamino)benzamide
Show/Hide
|
C25H28ClN5O2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 240 nM
|
|
|
|
CP0425168
|
(E)-6-chloro-4-(1-cinnamylpiperidin-4-ylamino)-1-methylquinolin-2(1H)-one
Show/Hide
|
C24H26ClN3O
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 88 nM
|
|
|
|
CP0146335
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C24H24N2O6
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 73 nM
|
|
|
|
CP0877511
|
4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylamino)-6-methoxy-chromen-2-one
Show/Hide
|
C23H24N2O5
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0110222
|
7-fluoro-N-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C22H20F2N2O3
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 966 nM
|
|
|
|
CP0376614
|
6-chloro-1-methyl-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)-2-oxo-1,2-dihydroquinoline-3-carbonitrile
Show/Hide
|
C27H25ClN4O
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 194 nM
|
|
|
|
CP0459718
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-pentylquinazolin-2(1H)-one
Show/Hide
|
C26H31ClN4O3
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0499986
|
6-chloro-1-methyl-4-(1-(quinolin-6-ylmethyl)piperidin-4-ylamino)quinazolin-2(1H)-one
Show/Hide
|
C24H24ClN5O
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 66 nM
|
|
|
|
CP0352050
|
7-fluoro-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C23H23FN2O4
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 101 nM
|
|
|
|
CP0051323
|
(S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]-propylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C31H37F2N5O6
|
1
|
| 1 |
IC50 = 15 nM
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CP0560227
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7-fluoro-N-[1-[[3-fluoro-4-[(2E)-2-(2-methylpropoxyimino)ethoxy]phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C28H31F2N3O5
|
2
|
| 1 |
IC50 = 15 nM
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| 2 |
IC50 = 1980 nM
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CP0386637
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4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile
Show/Hide
|
C23H21ClN4O3
|
2
|
| 1 |
IC50 = 15 nM
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| 2 |
IC50 = 20 nM
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CP0386628
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4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-methyl-3-(pyrrolidine-1-carbonyl)quinolin-2(1H)-one
Show/Hide
|
C28H31ClN4O4
|
2
|
| 1 |
IC50 = 16 nM
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| 2 |
IC50 = 53 nM
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CP0525307
|
7-fluoro-4-oxo-N-[1-[[4-(2-piperidin-1-ylethylcarbamoyl)phenyl]methyl]piperidin-4-yl]chromene-2-carboxamide
Show/Hide
|
C30H35FN4O4
|
2
|
| 1 |
IC50 = 17 nM
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| 2 |
IC50 = 519 nM
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CP0512340
|
7-fluoro-4-oxo-N-(1-((3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
|
C24H22FN3O5
|
1
|
| 1 |
IC50 = 19 nM
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CP0486688
|
6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C22H19ClF2N2O4
|
2
|
| 1 |
IC50 = 19 nM
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| 2 |
IC50 = 581 nM
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CP0406587
|
N-[3-(2-aminoquinolin-8-yl)oxypropyl]-3-(trifluoromethoxy)benzamide
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|
C20H18F3N3O3
|
1
|
| 1 |
IC50 = 20 nM
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CP0486393
|
3-Chloro-N-[3-(2-{[5-(2-chloro-phenyl)-furan-2-ylmethyl]-amino}-quinolin-8-yloxy)-propyl]-benzamide
Show/Hide
|
C30H25Cl2N3O3
|
1
|
| 1 |
IC50 = 20 nM
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CP0442411
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N-[1-[[4-[3-(dimethylamino)propoxy]-3-fluorophenyl]methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C27H31F2N3O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 773 nM
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CP0496770
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-[[(2R)-oxolan-2-yl]methylamino]pyridine-3-carboxamide
Show/Hide
|
C24H29ClN4O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 50 nM
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CP0503912
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(cyclopropylmethylamino)pyridine-3-carboxamide
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
IC50 = 20 nM
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CP0408065
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(2-methylpropylamino)pyridine-3-carboxamide
Show/Hide
|
C23H29ClN4O3
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 50 nM
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CP0431288
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(1H-imidazol-5-ylmethylamino)-5-methoxybenzamide
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C25H29N5O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 50 nM
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CP0461600
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-2-(pyridin-2-ylmethylamino)benzamide
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|
C27H30N4O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 370 nM
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CP0461609
|
N-[2-[[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]carbamoyl]-4-chlorophenyl]pyridine-2-carboxamide
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|
C26H25ClN4O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 370 nM
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CP0495199
|
5-Chloro-N-(1-quinolin-6-ylmethyl-piperidin-4-yl)-2-[(thiazol-2-ylmethyl)-amino]-benzamide
Show/Hide
|
C26H26ClN5OS
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 30 nM
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CP0495200
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(propan-2-ylamino)pyridine-3-carboxamide
Show/Hide
|
C22H27ClN4O3
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 30 nM
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CP0496768
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(1H-imidazol-2-ylmethylamino)pyridine-3-carboxamide
Show/Hide
|
C23H25ClN6O3
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 70 nM
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CP0514273
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-2-(oxolan-3-ylmethylamino)benzamide
Show/Hide
|
C26H33N3O5
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 40 nM
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CP0407895
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-1-(pyridin-3-ylmethyl)indazol-3-amine
Show/Hide
|
C26H26ClN5O2
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 290 nM
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CP0439039
|
(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-5-chloro-1H-indazol-1-yl)(thiazol-4-yl)methanone
Show/Hide
|
C24H22ClN5O3S
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 2540 nM
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CP0439040
|
(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-5-chloro-1H-indazol-1-yl)(pyridin-3-yl)methanone
Show/Hide
|
C26H24ClN5O3
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 930 nM
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CP0442381
|
5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl)-1-(pyridin-2-ylmethyl)-1H-indazol-3-amine
Show/Hide
|
C29H28ClN5
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 640 nM
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CP0495217
|
(1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-chloro-1Hindazol-3-yl)amine
Show/Hide
|
C20H21ClN4O2
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 260 nM
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CP0515610
|
1-(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-5-chloro-1H-indazol-1-yl)-2-morpholinoethanone
Show/Hide
|
C26H30ClN5O4
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 1140 nM
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CP0483656
|
6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-ylamino)-chromen-2-one
Show/Hide
|
C25H23ClN2O2
|
2
|
| 1 |
IC50 = 21 nM
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| 2 |
IC50 = 92 nM
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CP0179408
|
N-[1-[(6-chloro-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20ClFN2O5
|
2
|
| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 266 nM
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CP0854493
|
2-(4-Benzyloxy-benzylamino)-N-[3-(2-pyrrolidin-1-yl-ethyl)-3H-benzoimidazol-5-yl]-acetamide
Show/Hide
|
C29H31N3O2
|
2
|
| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 1470 nM
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CP0509434
|
8-[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
Show/Hide
|
C20H17F2N3O3
|
1
|
| 1 |
IC50 = 22.4 nM
|
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CP0449771
|
7-fluoro-N-[1-[[3-fluoro-4-(3-piperidin-1-ylpropanoylamino)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C30H34F2N4O4
|
2
|
| 1 |
IC50 = 23 nM
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| 2 |
IC50 = 120 nM
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CP0194259
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H21ClN2O5
|
2
|
| 1 |
IC50 = 24 nM
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| 2 |
IC50 > 10000 nM
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CP0289652
|
7-fluoro-N-[1-[(3-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C23H22F2N2O4
|
2
|
| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 168 nM
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CP0378909
|
6-Chloro-4-[1-(1H-indol-6-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C23H22ClN3O2
|
2
|
| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 28 nM
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CP0439495
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile
Show/Hide
|
C24H23ClN4O3
|
2
|
| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 69 nM
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CP0431566
|
2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-4-yl)acetamide
Show/Hide
|
C28H30N4O2
|
2
|
| 1 |
IC50 = 24.5 nM
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| 2 |
IC50 = 71 nM
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CP0442413
|
7-fluoro-N-[1-[[2-methoxy-4-(2-pyrrolidin-1-ylethylcarbamoyl)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C30H35FN4O5
|
2
|
| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 270 nM
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CP0442131
|
6-Chloro-4-[1-(2,3-dihydro-benzofuran-5-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
Show/Hide
|
C23H23ClN2O3
|
2
|
| 1 |
IC50 = 27 nM
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| 2 |
IC50 = 41 nM
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CP0458484
|
7-fluoro-N-[1-[[3-fluoro-4-(2-pyrrolidin-1-ylethylcarbamoyl)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C29H32F2N4O4
|
2
|
| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 420 nM
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CP0432857
|
8-[(S)-1-(4-tert-Butyl-benzyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
Show/Hide
|
C24H29N3O
|
1
|
| 1 |
IC50 = 30 nM
|
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CP0499081
|
8-((S)-1-Benzo[1,3]dioxol-5-ylmethyl-pyrrolidin-3-yloxy)-quinolin-2-ylamine
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 30 nM
|
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CP0379159
|
8-(2-Cyclopentylamino-1-methyl-ethoxy)-quinolin-2-ylamine
Show/Hide
|
C17H23N3O
|
1
|
| 1 |
IC50 = 30 nM
|
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CP0496911
|
N-[3-(2-aminoquinolin-8-yl)oxypropyl]-3-methoxybenzamide
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
IC50 = 30 nM
|
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CP0503911
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(cyclobutylamino)pyridine-3-carboxamide
Show/Hide
|
C23H27ClN4O3
|
2
|
| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 70 nM
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CP0393518
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-1-methylindazol-3-amine
Show/Hide
|
C22H26N4O3
|
2
|
| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 190 nM
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CP0515612
|
N-[1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)piperidin-4-yl]-5-nitro-1H-indazol-3-amine
Show/Hide
|
C21H23N5O4
|
2
|
| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 520 nM
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CP0110224
|
7-fluoro-N-[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C23H23FN2O4
|
2
|
| 1 |
IC50 = 31 nM
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| 2 |
IC50 = 390 nM
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CP0449770
|
7-fluoro-N-[1-[[3-fluoro-4-[(2E)-2-methoxyiminoethoxy]phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C25H25F2N3O5
|
2
|
| 1 |
IC50 = 31 nM
|
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| 2 |
IC50 = 480 nM
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CP0110215
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-bromo-4-oxochromene-2-carboxamide
Show/Hide
|
C23H21BrN2O5
|
2
|
| 1 |
IC50 = 32 nM
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| 2 |
IC50 = 82 nM
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CP0459721
|
4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-1-methyl-6-(trifluoromethoxy)quinolin-2(1H)-one
Show/Hide
|
C24H24F3N3O4
|
2
|
| 1 |
IC50 = 34 nM
|
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| 2 |
IC50 = 104 nM
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CP0514349
|
7-fluoro-N-[1-(1H-indol-5-ylmethyl)piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C24H22FN3O3
|
1
|
| 1 |
IC50 = 38 nM
|
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CP0352049
|
N-[1-[(4-acetylphenyl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C24H23FN2O4
|
2
|
| 1 |
IC50 = 39 nM
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| 2 |
IC50 = 581 nM
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CP0486372
|
N-[3-[2-[[5-(4-chlorophenyl)furan-2-yl]methylamino]quinolin-8-yl]oxypropyl]-3-cyanobenzamide
Show/Hide
|
C31H25ClN4O3
|
1
|
| 1 |
IC50 = 40 nM
|
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|
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CP0407894
|
(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-5-chloro-1H-indazol-1-yl)(cyclopropyl)methanone
Show/Hide
|
C24H25ClN4O3
|
2
|
| 1 |
IC50 = 40 nM
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| 2 |
IC50 > 10000 nM
|
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CP0498515
|
5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C23H23ClN4
|
2
|
| 1 |
IC50 = 40 nM
|
|
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| 2 |
IC50 = 1820 nM
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CP0515611
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-1-benzyl-5-chloroindazol-3-amine
Show/Hide
|
C27H27ClN4O2
|
2
|
| 1 |
IC50 = 40 nM
|
|
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| 2 |
IC50 = 5230 nM
|
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CP0485906
|
8-[1-[4-(2-methylpropyl)phenyl]pyrrolidin-3-yl]oxy-N-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methyl]quinolin-2-amine
Show/Hide
|
C35H34F3N3O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
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CP0431596
|
2-(4-Benzyloxy-phenyl)-N-[1-(2-pyrrolidin-1-yl-ethyl)-2H-indazol-4-yl]-acetamide
Show/Hide
|
C28H30N4O2
|
2
|
| 1 |
IC50 = 41.4 nM
|
|
|
| 2 |
IC50 = 287 nM
|
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CP0503189
|
7-fluoro-4-oxo-N-(1-((2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
|
C23H20FN3O5
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0153874
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-cyano-4-oxochromene-2-carboxamide
Show/Hide
|
C24H21N3O5
|
2
|
| 1 |
IC50 = 47 nM
|
|
|
| 2 |
IC50 = 137 nM
|
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|
|
CP0445992
|
N-[1-[(3-acetamidophenyl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C24H24FN3O4
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0502482
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(cyclohexylmethylamino)-5-methoxybenzamide
Show/Hide
|
C28H37N3O4
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 1060 nM
|
|
|
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CP0391615
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-1-phenylindazol-3-amine
Show/Hide
|
C26H25ClN4O2
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0407900
|
N-[1-(1H-indazol-6-ylmethyl)piperidin-4-yl]-5-methoxy-1H-indazol-3-amine
Show/Hide
|
C21H24N6O
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 380 nM
|
|
|
|
CP0407901
|
N-[1-(2,1,3-benzothiadiazol-5-ylmethyl)piperidin-4-yl]-5-chloro-1H-indazol-3-amine
Show/Hide
|
C19H19ClN6S
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 4910 nM
|
|
|
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CP0485472
|
8-[1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0382658
|
N-[1-[[4-[3-(dicyclopropylamino)propoxy]-3-fluorophenyl]methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
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C31H35F2N3O4
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2
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| 1 |
IC50 = 51 nM
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| 2 |
IC50 = 4010 nM
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CP0110221
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7-fluoro-N-[1-[(2-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
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C23H22F2N2O4
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2
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| 1 |
IC50 = 53 nM
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| 2 |
IC50 = 411 nM
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CP0485977
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8-[1-(4-Isobutyl-phenyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
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C23H27N3O
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1
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| 1 |
IC50 = 53.3 nM
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CP0352048
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N-[1-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
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C23H19F3N2O5
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2
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| 1 |
IC50 = 57 nM
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| 2 |
IC50 = 601 nM
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CP0194258
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-ethyl-4-oxochromene-2-carboxamide
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C25H26N2O5
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2
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| 1 |
IC50 = 59 nM
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| 2 |
IC50 = 529 nM
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CP0111441
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N-(1-benzylpiperidin-4-yl)-7-fluoro-4-oxochromene-2-carboxamide
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C22H21FN2O3
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2
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| 1 |
IC50 = 60 nM
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| 2 |
IC50 = 592 nM
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CP0461611
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5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-[(furan-2-ylmethyl)-amino]-nicotinamide
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C23H24Cl2N4O2
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2
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| 1 |
IC50 = 60 nM
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| 2 |
IC50 = 1220 nM
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CP0877869
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6-Chloro-4-[1-(1-methyl-1H-indol-6-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
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C24H24ClN3O2
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2
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| 1 |
IC50 = 60 nM
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| 2 |
IC50 = 162 nM
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CP0352045
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-(difluoromethoxy)-4-oxochromene-2-carboxamide
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C24H22F2N2O6
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2
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| 1 |
IC50 = 64 nM
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| 2 |
IC50 = 160 nM
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CP0523125
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7-fluoro-N-[1-[[3-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
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C24H21F5N2O4
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1
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| 1 |
IC50 = 64 nM
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CP0077797
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide
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C23H21FN2O5
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2
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| 1 |
IC50 = 65 nM
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| 2 |
IC50 = 196 nM
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CP0153875
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
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C23H22N2O5
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2
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| 1 |
IC50 = 66 nM
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| 2 |
IC50 = 192 nM
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CP0480681
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Benzo[1,3]dioxole-5-carboxylic acid [3-(2-amino-quinolin-8-yloxy)-propyl]-amide
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C20H19N3O4
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1
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| 1 |
IC50 = 70 nM
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CP0392096
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(1H-imidazol-2-ylmethylamino)-5-methoxybenzamide
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C25H29N5O4
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2
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| 1 |
IC50 = 70 nM
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| 2 |
IC50 = 220 nM
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CP0408064
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5-Chloro-N-[1-(2,3-dihydro-benzofuran-5-ylmethyl)-piperidin-4-yl]-2-isopropylamino-nicotinamide
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C23H29ClN4O2
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1
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| 1 |
IC50 = 70 nM
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CP0428236
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2-[(3H-Imidazol-4-ylmethyl)-amino]-5-methoxy-N-(1-quinolin-6-ylmethyl-piperidin-4-yl)-benzamide
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C27H30N6O2
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2
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| 1 |
IC50 = 70 nM
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| 2 |
IC50 = 100 nM
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CP0493122
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5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)piperidin-4-yl)-1H-indazol-3-amine
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C21H23ClN4O2
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2
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| 1 |
IC50 = 70 nM
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| 2 |
IC50 = 1890 nM
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CP0179407
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N-[1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
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C24H23FN2O5
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2
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| 1 |
IC50 = 73 nM
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| 2 |
IC50 = 171 nM
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CP0832694
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5,6-dichloro-4-oxo-4H-chromene-2-carboxamide
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C23H20Cl2N2O5
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2
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| 1 |
IC50 = 75 nM
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| 2 |
IC50 = 4750 nM
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CP0378908
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4-(1-Benzooxazol-6-ylmethyl-piperidin-4-ylamino)-6-chloro-chromen-2-one
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C22H20ClN3O3
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2
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| 1 |
IC50 = 75 nM
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| 2 |
IC50 = 461 nM
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CP0425151
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8-[1-(2-Benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
Show/Hide
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C23H25N3O3
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1
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| 1 |
IC50 = 79.2 nM
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CP0515938
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-hydroxybenzamide
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C20H21ClN2O4
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2
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| 1 |
IC50 = 80 nM
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| 2 |
IC50 = 510 nM
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CP0560226
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N-[1-[[4-[2-(4,4-difluoropiperidin-1-yl)ethylcarbamoyl]phenyl]methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
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C30H33F3N4O4
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2
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| 1 |
IC50 = 86 nM
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| 2 |
IC50 = 2930 nM
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CP0485820
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methoxy-2-[(3-methylimidazol-4-yl)methylamino]benzamide
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C26H31N5O4
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2
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| 1 |
IC50 = 90 nM
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| 2 |
IC50 = 100 nM
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CP0110218
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6,7,8-trifluoro-4-oxochromene-2-carboxamide
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C23H19F3N2O5
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2
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| 1 |
IC50 = 91 nM
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| 2 |
IC50 = 418 nM
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CP0512339
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N-[1-[(2-ethyl-1,3-benzoxazol-5-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C25H24FN3O4
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1
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| 1 |
IC50 = 95 nM
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CP0499987
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methyl 4-[[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]amino]-6-chloro-1-methyl-2-oxoquinoline-3-carboxylate
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C25H26ClN3O5
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2
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| 1 |
IC50 = 97 nM
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| 2 |
IC50 = 452 nM
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CP0179393
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6,8-difluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20F2N2O5
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2
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| 1 |
IC50 = 99 nM
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| 2 |
IC50 = 2720 nM
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CP0435409
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8-[3-(2,2-Difluoro-benzo[1,3]dioxol-5-ylamino)-propoxy]-quinolin-2-ylamine
Show/Hide
|
C19H17F2N3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0462005
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8-[2-(Cyclopentylmethyl-amino)-1-methyl-ethoxy]-quinolin-2-ylamine
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C18H25N3O
|
1
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| 1 |
IC50 = 100 nM
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CP0497062
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8-{2-[(Furan-3-ylmethyl)-amino]-1-methyl-ethoxy}-quinolin-2-ylamine
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C17H19N3O2
|
1
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| 1 |
IC50 = 100 nM
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CP0498529
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5-chloro-N-[1-[(3,4-dimethylphenyl)methyl]piperidin-4-yl]-1H-indazol-3-amine
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C21H25ClN4
|
2
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| 1 |
IC50 = 100 nM
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| 2 |
IC50 = 1380 nM
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CP0504934
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1-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-benzo[1,3]dioxol-5-yl-urea
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C20H20N4O4
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1
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| 1 |
IC50 = 110 nM
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CP0403379
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-3-chlorobenzamide
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C20H21ClN2O3
|
1
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| 1 |
IC50 = 110 nM
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CP0442181
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-methyl-1H-indazol-3-amine
Show/Hide
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C21H24N4O2
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2
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| 1 |
IC50 = 110 nM
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| 2 |
IC50 = 1060 nM
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CP0420125
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8-{2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-1-methyl-ethoxy}-quinolin-2-ylamine
Show/Hide
|
C20H21N3O3
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1
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| 1 |
IC50 = 130 nM
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CP0077795
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4-oxo-6-(trifluoromethoxy)chromene-2-carboxamide
Show/Hide
|
C24H21F3N2O6
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2
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| 1 |
IC50 = 132 nM
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| 2 |
IC50 > 9000 nM
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CP0451879
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N-[3-(2-aminoquinolin-8-yl)oxypropyl]-4-propan-2-ylbenzamide
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C22H25N3O2
|
1
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| 1 |
IC50 = 140 nM
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CP0505669
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6-(2-Isopropoxy-ethylamino)-[3,4']bipyridinyl-5-carboxylic acid (1-benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-amide
Show/Hide
|
C29H35N5O4
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1
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| 1 |
IC50 = 140 nM
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CP0436459
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2-(4-Benzyloxy-phenyl)-N-[2-(2-pyrrolidin-1-yl-ethyl)-2H-indazol-6-yl]-acetamide
Show/Hide
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C28H30N4O2
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2
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| 1 |
IC50 = 146 nM
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| 2 |
IC50 = 874 nM
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CP0485125
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8-{1-Methyl-2-[(thiophen-3-ylmethyl)-amino]-ethoxy}-quinolin-2-ylamine
Show/Hide
|
C17H19N3OS
|
1
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| 1 |
IC50 = 150 nM
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CP0407898
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5-chloro-N-[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]-1H-indazol-3-amine
Show/Hide
|
C20H23ClN4O
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2
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| 1 |
IC50 = 150 nM
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| 2 |
IC50 = 4500 nM
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CP0289650
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7-fluoro-N-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C22H20F2N2O3
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2
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| 1 |
IC50 = 159 nM
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| 2 |
IC50 = 789 nM
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CP0485819
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N-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-2-(methanesulfonamido)-5-methoxybenzamide
Show/Hide
|
C21H26ClN3O4S
|
1
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| 1 |
IC50 = 160 nM
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CP0528334
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5-Chloro-N-[1-(3-fluoro-4-methoxy-benzyl)-piperidin-4-yl]-2-isobutylamino-nicotinamide
Show/Hide
|
C23H30ClFN4O2
|
1
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| 1 |
IC50 = 160 nM
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CP0444877
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7-fluoro-N-[1-[[4-(3-methoxy-3-methylbutoxy)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
|
C28H33FN2O5
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2
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| 1 |
IC50 = 165 nM
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| 2 |
IC50 = 1750 nM
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CP0499938
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7-fluoro-4-oxo-N-(1-((3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
|
C24H22FN3O5
|
1
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| 1 |
IC50 = 166 nM
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CP0111455
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4-oxo-7-(trifluoromethyl)chromene-2-carboxamide
Show/Hide
|
C24H21F3N2O5
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2
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| 1 |
IC50 = 178 nM
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| 2 |
IC50 = 3070 nM
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CP0171126
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-bromo-4-oxochromene-2-carboxamide
Show/Hide
|
C23H21BrN2O5
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2
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| 1 |
IC50 = 187 nM
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| 2 |
IC50 > 6000 nM
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CP0431007
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8-(1-Methyl-2-morpholin-4-yl-ethoxy)-quinolin-2-ylamine
Show/Hide
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C16H21N3O2
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1
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| 1 |
IC50 = 190 nM
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CP0505668
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(2-propan-2-yloxyethylamino)-5-thiophen-2-ylpyridine-3-carboxamide
Show/Hide
|
C28H34N4O4S
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1
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| 1 |
IC50 = 190 nM
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CP0428052
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4-{1-[((E)-3-Phenyl)-allyl]-piperidin-4-ylamino}-chromen-2-one
Show/Hide
|
C23H24N2O2
|
2
|
| 1 |
IC50 = 191 nM
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| 2 |
IC50 = 1036 nM
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CP0524442
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5-chloro-N-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-indazol-3-amine
Show/Hide
|
C19H20Cl2N4
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2
|
| 1 |
IC50 = 200 nM
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| 2 |
IC50 = 6200 nM
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CP0464619
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8-[3-(4-Chloro-3-trifluoromethyl-benzylamino)-propoxy]-quinolin-2-ylamine
Show/Hide
|
C20H19ClF3N3O
|
1
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| 1 |
IC50 = 220 nM
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CP0498513
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N-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-5-methoxy-2-(propan-2-ylcarbamoylamino)benzamide
Show/Hide
|
C24H31ClN4O3
|
1
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| 1 |
IC50 = 220 nM
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CP0493121
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3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-1H-indazole-5-carbonitrile
Show/Hide
|
C21H21N5O2
|
2
|
| 1 |
IC50 = 220 nM
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| 2 |
IC50 = 3400 nM
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CP0485112
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8-[1-(1-Phenyl-propyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
Show/Hide
|
C22H25N3O
|
1
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| 1 |
IC50 = 224 nM
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CP0442184
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5-chloro-N-[1-[(2-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl]-1H-indazol-3-amine
Show/Hide
|
C20H22ClFN4O
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2
|
| 1 |
IC50 = 240 nM
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| 2 |
IC50 = 5200 nM
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CP0506264
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8-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-3-yl]oxy-N-methylquinolin-2-amine
Show/Hide
|
C22H23N3O3
|
1
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| 1 |
IC50 = 244 nM
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CP0515939
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(methanesulfonamido)-5-methoxybenzamide
Show/Hide
|
C22H27N3O6S
|
1
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| 1 |
IC50 = 260 nM
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CP0497074
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8-[3-(Benzo[1,3]dioxol-5-ylamino)-propoxy]-quinolin-2-ylamine
Show/Hide
|
C19H19N3O3
|
1
|
| 1 |
IC50 = 270 nM
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CP0407897
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5-chloro-N-(1-((7-methoxybenzo[d][1,3]dioxol-5-yl)methyl)piperidin-4-yl)-1H-indazol-3-amine
Show/Hide
|
C21H23ClN4O3
|
2
|
| 1 |
IC50 = 280 nM
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| 2 |
IC50 > 10000 nM
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CP0445583
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8-(1-Methyl-2-piperidin-1-yl-ethoxy)-quinolin-2-ylamine
Show/Hide
|
C17H23N3O
|
1
|
| 1 |
IC50 = 290 nM
|
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CP0431561
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2-(4-Phenoxy-benzylamino)-N-[3-(2-pyrrolidin-1-yl-ethyl)-3H-benzoimidazol-5-yl]-acetamide
Show/Hide
|
C28H31N5O2
|
2
|
| 1 |
IC50 = 299 nM
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| 2 |
IC50 = 1810 nM
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CP0480331
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-4-methoxy-1H-indazol-3-amine
Show/Hide
|
C21H24N4O3
|
2
|
| 1 |
IC50 = 330 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0430063
|
8-(2-Benzylamino-1-methyl-ethoxy)-quinolin-2-ylamine
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
IC50 = 340 nM
|
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|
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CP0194260
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4-oxo-7-trifluoromethyl-4H-chromene-2-carboxylic acid (1-benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)amide
Show/Hide
|
C24H21F3N2O5
|
1
|
| 1 |
IC50 = 351 nM
|
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CP0445582
|
8-(1-Methyl-2-pyrrolidin-1-yl-ethoxy)-quinolin-2-ylamine
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
IC50 = 360 nM
|
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CP0428235
|
2-[(3H-Imidazol-4-ylmethyl)-amino]-5-methoxy-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl)-benzamide
Show/Hide
|
C28H31N5O2
|
2
|
| 1 |
IC50 = 390 nM
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|
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| 2 |
IC50 = 1940 nM
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CP0339654
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-methyl-4-oxochromene-2-carboxamide
Show/Hide
|
C24H24N2O5
|
1
|
| 1 |
IC50 = 393 nM
|
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CP0461610
|
5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-(cyclopropylmethyl-amino)-nicotinamide
Show/Hide
|
C22H26Cl2N4O
|
1
|
| 1 |
IC50 = 410 nM
|
|
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CP0528333
|
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2-(1H-imidazol-5-ylmethylamino)benzamide
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
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CP0077800
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N-[1-[(3,4-dimethoxyphenyl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
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C24H25FN2O5
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1
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| 1 |
IC50 = 427 nM
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CP0515613
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-1H-indazol-3-amine
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C20H22N4O2
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2
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| 1 |
IC50 = 440 nM
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| 2 |
IC50 > 10000 nM
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CP0445606
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8-[2-(Cyclopropylmethyl-amino)-1-methyl-ethoxy]-quinolin-2-ylamine
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C16H21N3O
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1
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| 1 |
IC50 = 460 nM
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CP0430890
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N-[[5-(2-chlorophenyl)furan-2-yl]methyl]-8-(4,4-dimethylpentan-2-yloxy)quinolin-2-amine
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C27H29ClN2O2
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1
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| 1 |
IC50 = 530 nM
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CP0485478
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8-[(R)-1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
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C20H17F2N3O3
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1
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| 1 |
IC50 = 531 nM
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CP0475868
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2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)acetamide
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C28H30N4O2
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2
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| 1 |
IC50 = 558 nM
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| 2 |
IC50 > 10000 nM
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CP0515642
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(methanesulfonamido)benzamide
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C21H24ClN3O5S
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1
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| 1 |
IC50 = 560 nM
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CP0110223
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7-fluoro-N-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
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C22H20F2N2O3
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2
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| 1 |
IC50 = 566 nM
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| 2 |
IC50 = 2150 nM
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CP0430062
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8-(2-Cyclopropylamino-1-methyl-ethoxy)-quinolin-2-ylamine
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C15H19N3O
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1
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| 1 |
IC50 = 580 nM
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CP0429998
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8-[2-(3-Methoxy-benzylamino)-1-methyl-ethoxy]-quinolin-2-ylamine
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C20H23N3O2
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1
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| 1 |
IC50 = 600 nM
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CP0485711
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8-[3-(4-Isopropyl-benzylamino)-propoxy]-quinolin-2-ylamine
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C22H27N3O
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1
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| 1 |
IC50 = 630 nM
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CP0514272
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-(methylamino)benzamide
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C21H24ClN3O3
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1
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| 1 |
IC50 = 680 nM
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CP0339655
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-chloro-4-oxochromene-2-carboxamide
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C23H21ClN2O5
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2
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| 1 |
IC50 = 734 nM
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| 2 |
IC50 = 2050 nM
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CP0498530
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N-(1-benzylpiperidin-4-yl)-5-chloro-1H-indazol-3-amine
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C19H21ClN4
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2
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| 1 |
IC50 = 850 nM
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| 2 |
IC50 > 10000 nM
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CP0435402
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8-(1-Methyl-butoxy)-quinolin-2-ylamine
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C14H18N2O
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1
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| 1 |
IC50 = 860 nM
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CP0413189
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4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide
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C26H27FN2O
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1
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| 1 |
IC50 = 872 nM
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CP0499082
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3-Chloro-N-[3-(2-propylamino-quinolin-8-yloxy)-propyl]-benzamide
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C22H24ClN3O2
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1
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| 1 |
IC50 = 1120 nM
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CP0441714
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8-[(S)-1-(4-tert-Butyl-benzenesulfonyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
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C23H27N3O3S
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1
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| 1 |
IC50 = 1140 nM
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CP0419502
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N-[[1-(1,3-benzodioxol-5-ylmethyl)pyrrolidin-3-yl]methyl]-7-methoxy-4-oxochromene-2-carboxamide
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C24H24N2O6
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2
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| 1 |
IC50 = 1140 nM
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| 2 |
IC50 = 8300 nM
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CP0437086
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N-[4-[[(3S)-3-(2-aminoquinolin-8-yl)oxypyrrolidin-1-yl]methyl]phenyl]acetamide
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C22H24N4O2
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1
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| 1 |
IC50 = 1260 nM
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CP0514350
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N-[1-[(2-ethyl-1,3-benzoxazol-6-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
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C25H24FN3O4
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1
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| 1 |
IC50 = 1267 nM
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CP0420124
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8-(2-Ethyl-1-methyl-butoxy)-quinolin-2-ylamine
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C16H22N2O
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1
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| 1 |
IC50 = 1300 nM
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CP0497059
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8-(2-Methyl-cyclohexyloxy)-quinolin-2-ylamine
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C16H20N2O
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1
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| 1 |
IC50 = 1330 nM
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CP0111454
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-hydroxy-4-oxochromene-2-carboxamide
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C23H22N2O6
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2
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| 1 |
IC50 = 1480 nM
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| 2 |
IC50 > 10000 nM
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CP0382657
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7-fluoro-N-[1-[[3-fluoro-4-(2-pyrrolidin-1-ylethoxy)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
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C28H31F2N3O4
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2
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| 1 |
IC50 = 1520 nM
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| 2 |
IC50 > 10000 nM
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CP0420188
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8-((R)-1-Benzo[1,3]dioxol-5-ylmethyl-pyrrolidin-3-yloxy)-quinolin-2-ylamine
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C21H21N3O3
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1
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| 1 |
IC50 = 1600 nM
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CP0378075
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8-Cyclohexylmethoxy-quinolin-2-ylamine
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C16H20N2O
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1
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| 1 |
IC50 = 1680 nM
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CP0491955
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8-((S)-1-Benzyl-pyrrolidin-3-yloxy)-quinolin-2-ylamine
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C20H21N3O
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1
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| 1 |
IC50 = 1690 nM
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CP0339657
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N-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
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C24H24FN3O4
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3
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| 1 |
IC50 = 1690 nM
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| 2 |
IC50 = 1700 nM
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| 3 |
IC50 > 10000 nM
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CP0445777
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8-(Bicyclo[2.2.1]hept-2-ylmethoxy)-quinolin-2-ylamine
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C17H20N2O
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1
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| 1 |
IC50 = 1730 nM
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CP0515692
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5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-cyclobutylamino-nicotinamide
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C22H26Cl2N4O
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1
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| 1 |
IC50 = 1980 nM
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CP0393232
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2-(4-Benzyloxy-phenyl)-N-[1-(2-pyrrolidin-1-yl-ethyl)-2H-indazol-5-yl]-acetamide
Show/Hide
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C28H30N4O2
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2
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| 1 |
IC50 = 1985 nM
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| 2 |
IC50 > 10000 nM
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CP0499937
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7-fluoro-4-oxo-N-(1-((2-oxobenzo[d][1,3]dioxol-5-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide
Show/Hide
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C23H19FN2O6
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1
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| 1 |
IC50 = 2010 nM
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CP0515691
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-2,5-dichloropyridine-3-carboxamide
Show/Hide
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C19H19Cl2N3O3
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1
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| 1 |
IC50 = 2010 nM
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CP0509710
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8-(2-Cyclohexylamino-1-methyl-ethoxy)-quinolin-2-ylamine
Show/Hide
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C18H25N3O
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1
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| 1 |
IC50 = 2170 nM
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CP0436416
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8-Cyclopentylmethoxy-quinolin-2-ylamine
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C15H18N2O
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1
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| 1 |
IC50 = 2290 nM
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CP0467274
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1-Benzo[1,3]dioxol-5-yl-3-[3-(2-{[5-(2-chloro-phenyl)-furan-2-ylmethyl]-amino}-quinolin-8-yloxy)-propyl]-urea
Show/Hide
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C31H27ClN4O5
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1
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| 1 |
IC50 = 3110 nM
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CP0485903
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8-Cycloheptyloxy-quinolin-2-ylamine
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C16H20N2O
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1
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| 1 |
IC50 = 3480 nM
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CP0448790
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8-(3-Methoxy-3-methyl-butoxy)-quinolin-2-ylamine
Show/Hide
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C15H20N2O2
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1
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| 1 |
IC50 = 4670 nM
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CP0485495
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8-sec-Butoxy-quinolin-2-ylamine
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C13H16N2O
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1
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| 1 |
IC50 = 5310 nM
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CP0448792
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8-(4,4-dimethylpentan-2-yloxy)-N-methylquinolin-2-amine
Show/Hide
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C17H24N2O
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1
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| 1 |
IC50 = 6090 nM
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CP0430893
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8-(Tetrahydro-furan-3-ylmethoxy)-quinolin-2-ylamine
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C14H16N2O2
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1
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| 1 |
IC50 = 6240 nM
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CP0391245
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8-[2-(1H-Indazol-5-ylamino)-1-methyl-ethoxy]-quinolin-2-ylamine
Show/Hide
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C19H19N5O
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1
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| 1 |
IC50 = 8180 nM
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CP0485905
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8-{2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-ethoxy}-quinolin-2-ylamine
Show/Hide
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C19H19N3O3
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1
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| 1 |
IC50 = 8960 nM
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CP0425147
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[(3S)-3-(2-aminoquinolin-8-yl)oxypyrrolidin-1-yl]-(1,3-benzodioxol-5-yl)methanone
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C21H19N3O4
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1
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| 1 |
IC50 = 9140 nM
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CP0420128
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8-[1-(1,3-benzodioxol-5-yl)pyrrolidin-3-yl]oxy-N,N-dimethylquinolin-2-amine
Show/Hide
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C22H23N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0420129
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N-(cyclopropylmethyl)-8-[1-[4-(2-methylpropyl)phenyl]pyrrolidin-3-yl]oxyquinolin-2-amine
Show/Hide
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C27H33N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0491957
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8-((R)-1-Benzyl-pyrrolidin-3-yloxy)-quinolin-2-ylamine
Show/Hide
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C20H21N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0430891
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8-(4,4-dimethylpentan-2-yloxy)-N,N-dimethylquinolin-2-amine
Show/Hide
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C18H26N2O
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1
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| 1 |
IC50 > 10000 nM
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CP0495067
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N-(cyclopropylmethyl)-8-(4,4-dimethylpentan-2-yloxy)quinolin-2-amine
Show/Hide
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C20H28N2O
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1
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| 1 |
IC50 > 10000 nM
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CP0497233
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8-(1,3,3-Trimethyl-butoxy)-quinoline
Show/Hide
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C16H21NO
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1
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| 1 |
IC50 > 10000 nM
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CP0508708
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2-Pyrrolidin-1-yl-8-(1,3,3-trimethyl-butoxy)-quinoline
Show/Hide
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C20H28N2O
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1
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| 1 |
IC50 > 10000 nM
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CP0515905
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2-Piperidin-1-yl-8-(1,3,3-trimethyl-butoxy)-quinoline
Show/Hide
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C21H30N2O
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1
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| 1 |
IC50 > 10000 nM
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CP0522606
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8-{2-[(Furan-3-ylmethyl)-amino]-ethoxy}-quinolin-2-ylamine
Show/Hide
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C16H17N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0918943
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4-[1-(4-tert-Butyl-benzyl)-piperidin-4-ylamino]-6-chloro-chromen-2-one
Show/Hide
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C25H29ClN2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0442383
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N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-(trifluoromethyl)-1H-indazol-3-amine
Show/Hide
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C21H21F3N4O2
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
IC50 > 2000 nM
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CP0409076
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2-(4-Benzyloxy-phenyl)-N-[1-(2-pyrrolidin-1-yl-ethyl)-1H-benzoimidazol-5-yl]-acetamide
Show/Hide
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C28H30N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0486144
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2-(4-Benzyloxy-benzylamino)-N-[3-(2-pyrrolidin-1-yl-ethyl)-3H-benzoimidazol-5-yl]-acetamide
Show/Hide
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C28H30N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0408411
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N-[1-(1,3-benzodioxol-4-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
Show/Hide
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C23H21FN2O5
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1
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| 1 |
IC50 > 700 nM
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CP0408402
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7-methoxy-4-oxo-4H-chromene-2-carboxylic acid [2-(1-benzo-[1,3]dioxol-5-ylmethylpyrrolidin-2-yl)ethyl]amide
Show/Hide
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C25H26N2O6
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1
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| 1 |
IC50 > 2000 nM
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CP0424729
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7-methoxy-4-oxo-4H-chromene-2-carboxylic acid (4-{[(Benzo-[1,3]dioxol-5-ylmethyl)amino]methyl}cyclohexyl)amide
Show/Hide
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C25H26N2O6
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1
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| 1 |
IC50 > 2000 nM
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CP0432143
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7-methoxy-4-oxo-4H-chromene-2-carboxylic acid (1-benzo-[1,3]dioxol-5-ylmethylpiperidin-3-yl)amide
Show/Hide
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C24H24N2O6
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1
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| 1 |
IC50 > 2000 nM
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CP0453662
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7-methoxy-4-oxo-4H-chromene-2-carboxylic acid (1-benzo-[1,3]dioxol-5-ylmethylpyrrolidin-3-yl)amide
Show/Hide
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C23H22N2O6
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1
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| 1 |
IC50 > 2000 nM
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CP0521592
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2-(4-benzo[1,3]dioxol-5-ylmethylpiperazine-1-carbonyl)-7-methoxychromen-4-one
Show/Hide
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C23H22N2O6
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1
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| 1 |
IC50 > 2000 nM
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CP0501794
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7-fluoro-N-[1-[[3-fluoro-4-(2-morpholin-4-ylethoxy)phenyl]methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide
Show/Hide
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C28H31F2N3O5
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1
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| 1 |
IC50 > 2000 nM
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