Brief Information of the Compound and Protein
Compound Name
5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-[(furan-2-ylmethyl)-amino]-nicotinamide
    Show/Hide
PubChem ID
CID: 44403501
Canonical SMILES
Clc1ccc(CN2CCC(CC2)NC(=O)c2cc(Cl)cnc2NCc2ccco2)cc1
    Show/Hide
Compound Formula C23H24Cl2N4O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  2
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
2
IC50 = 1220 nM
   TI
   LI
   LO
   TS