Cell Line ID	CL000016
Cell Line Name	IMR-32
Synonyms	IMR 32 IMR32 Institute for Medical Research-32 GM03320 GM3320C GM03320D AG03320 AG3320
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0346
Tissue Information	Abdomen
Disease	Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635)

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Compound ID	Compound Name	Compound Formula
CP0071313  Compound Info	(2R,3R,4S,5R)-2-(2-amino-9-iodo-3,5,7-triazabicyclo[4.3.0]nona-1,3,5,8-tetraen-7-yl)-5-methyl-oxolane-3,4-diol    Show/Hide	C11H13IN4O3	1
1	IC50 = 22.8 nM  Bioactivity Info	TI    LI    LO    TS
CP0528733  Compound Info	5-(4-Bromo-thiophen-2-yl)-6-(3,4-dimethoxy-phenyl)-7-thiophen-2-yl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C23H17BrN4O2S2	1
1	IC50 = 25 nM  Bioactivity Info	TI    LI    LO    TS
CP0198332  Compound Info	5-(3-Bromo-phenyl)-7-(6-dimethylamino-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C20H17BrN6	1
1	IC50 = 32 nM  Bioactivity Info	TI    LI    LO    TS
CP0550871  Compound Info	5,6-Diphenyl-7-thiophen-2-yl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C23H16N4S	1
1	IC50 = 49 nM  Bioactivity Info	TI    LI    LO    TS
CP0103761  Compound Info	5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C22H19BrN6O	1
1	IC50 = 50 nM  Bioactivity Info	TI    LI    LO    TS
CP0507642  Compound Info	7-(6-Dimethylamino-pyridin-3-yl)-5,6-diphenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C26H22N6	1
1	IC50 = 53 nM  Bioactivity Info	TI    LI    LO    TS
CP0437004  Compound Info	5-(3-Chloro-phenyl)-7-(6-dimethylamino-pyridin-3-yl)-6-phenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C26H21ClN6	1
1	IC50 = 130 nM  Bioactivity Info	TI    LI    LO    TS
CP0518331  Compound Info	5-(3-Chloro-phenyl)-6-(4-dimethylamino-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C30H28ClN7O	1
1	IC50 = 130 nM  Bioactivity Info	TI    LI    LO    TS
CP0138070  Compound Info	(2R,3R,4S,5R)-2-[4-(4-Fluoro-phenylamino)-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl]-5-methyl-tetrahydro-furan-3,4-diol    Show/Hide	C23H21FN4O3	1
1	IC50 = 134 nM  Bioactivity Info	TI    LI    LO    TS
CP0492876  Compound Info	5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-6-phenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C28H23BrN6O	1
1	IC50 = 155 nM  Bioactivity Info	TI    LI    LO    TS
CP0402039  Compound Info	methyl 2-[4-amino-5-(3-bromophenyl)-7-thiophen-2-ylpyrido[2,3-d]pyrimidin-6-yl]acetate    Show/Hide	C20H15BrN4O2S	1
1	IC50 = 163 nM  Bioactivity Info	TI    LI    LO    TS
CP0200853  Compound Info	5-(3-Bromo-phenyl)-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C21H18BrN5	1
1	IC50 = 167 nM  Bioactivity Info	TI    LI    LO    TS
CP0383205  Compound Info	5-(3-Bromo-phenyl)-6-(4-fluoro-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C28H22BrFN6O	1
1	IC50 = 197 nM  Bioactivity Info	TI    LI    LO    TS
CP0425859  Compound Info	7-(4-Dimethylamino-phenyl)-5,6-diphenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C27H23N5	1
1	IC50 = 250 nM  Bioactivity Info	TI    LI    LO    TS
CP0431457  Compound Info	5,6-Bis-(3-fluoro-4-methyl-phenyl)-7-thiophen-2-yl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C25H18F2N4S	1
1	IC50 = 288 nM  Bioactivity Info	TI    LI    LO    TS
CP0366798  Compound Info	7-(4-Dimethylamino-phenyl)-6-phenyl-pteridin-4-ylamine    Show/Hide	C20H18N6	1
1	IC50 = 333 nM  Bioactivity Info	TI    LI    LO    TS
CP0480643  Compound Info	5-(3-Bromo-phenyl)-6-(3,4-dimethoxy-phenyl)-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C29H26BrN5O2	1
1	IC50 = 350 nM  Bioactivity Info	TI    LI    LO    TS
CP0460157  Compound Info	5-(4-Bromo-thiophen-2-yl)-6-(3,4-dimethoxy-phenyl)-7-{4-[(2-methoxy-ethyl)-methyl-amino]-phenyl}-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C29H28BrN5O3S	1
1	IC50 = 367 nM  Bioactivity Info	TI    LI    LO    TS
CP0406658  Compound Info	6-Benzyl-5-(3-bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C29H25BrN6O	1
1	IC50 = 450 nM  Bioactivity Info	TI    LI    LO    TS
CP0047724  Compound Info	7-(4-Dimethylamino-phenyl)-5-phenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C21H19N5	1
1	IC50 = 467 nM  Bioactivity Info	TI    LI    LO    TS
CP0134601  Compound Info	5-Cyclohexyl-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C21H25N5	1
1	IC50 = 467 nM  Bioactivity Info	TI    LI    LO    TS
CP0166322  Compound Info	7-(4-Dimethylamino-phenyl)-6-p-tolyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C22H21N5	1
1	IC50 = 500 nM  Bioactivity Info	TI    LI    LO    TS
CP0281006  Compound Info	7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C22H21N5O	1
1	IC50 = 567 nM  Bioactivity Info	TI    LI    LO    TS
CP0448113  Compound Info	5-(3-Bromo-phenyl)-7-(6-dimethylamino-pyridin-3-yl)-6-pentyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C25H27BrN6	1
1	IC50 = 625 nM  Bioactivity Info	TI    LI    LO    TS
CP0495479  Compound Info	5-(4-Bromo-thiophen-2-yl)-6-cyclopropyl-7-(6-dimethylamino-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C21H19BrN6S	1
1	IC50 = 625 nM  Bioactivity Info	TI    LI    LO    TS
CP0079164  Compound Info	3-[4-Amino-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-6-yl]-benzoic acid methyl ester    Show/Hide	C23H21N5O2	1
1	IC50 = 700 nM  Bioactivity Info	TI    LI    LO    TS
CP0276766  Compound Info	7-(4-Morpholin-4-yl-phenyl)-pteridin-4-ylamine    Show/Hide	C16H16N6O	1
1	IC50 = 1000 nM  Bioactivity Info	TI    LI    LO    TS
CP0281868  Compound Info	7-(4-Dimethylamino-phenyl)-6-phenyl-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C21H19N5	1
1	IC50 = 1500 nM  Bioactivity Info	TI    LI    LO    TS
CP0076829  Compound Info	7-(4-Dimethylamino-phenyl)-pteridin-4-ylamine    Show/Hide	C14H14N6	1
1	IC50 = 3600 nM  Bioactivity Info	TI    LI    LO    TS
CP0257633  Compound Info	(2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol    Show/Hide	C10H14N6O3	1
1	IC50 = 6330 nM  Bioactivity Info	TI    LI    LO    TS
CP0049447  Compound Info	7-(4-Dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C15H15N5	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0078974  Compound Info	7-Phenyl-pteridin-4-ylamine    Show/Hide	C12H9N5	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0220501  Compound Info	7-(4-Methoxy-phenyl)-pteridin-4-ylamine    Show/Hide	C13H11N5O	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0252859  Compound Info	7-(4-Amino-phenyl)-pteridin-4-ylamine    Show/Hide	C12H10N6	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0366787  Compound Info	7-(4-Nitro-phenyl)-pteridin-4-ylamine    Show/Hide	C12H8N6O2	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0382304  Compound Info	7-(4-Chloro-phenyl)-4-morpholin-4-yl-pteridine    Show/Hide	C16H14ClN5O	1
1	IC50 = 22000 nM  Bioactivity Info	TI    LI    LO    TS
CP0179736  Compound Info	(2R,3R,4S,5R)-2-(6-Amino-5-nitro-pyrimidin-4-ylamino)-5-hydroxymethyl-tetrahydro-furan-3,4-diol    Show/Hide	C9H13N5O6	1
1	IC50 = 26000 nM  Bioactivity Info	TI    LI    LO    TS
CP0161822  Compound Info	6-(4-tert-Butyl-phenyl)-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C25H27N5	1
1	IC50 > 1000 nM  Bioactivity Info	TI    LI    LO    TS
CP0399477  Compound Info	7-(4-Dimethylamino-phenyl)-5,6-bis-(4-isopropyl-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C33H35N5	1
1	IC50 > 1000 nM  Bioactivity Info	TI    LI    LO    TS
CP0503565  Compound Info	5-(3-Bromo-phenyl)-6-isopropyl-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C25H25BrN6O	1
1	IC50 > 1000 nM  Bioactivity Info	TI    LI    LO    TS
CP0505927  Compound Info	5-(3-Bromo-phenyl)-6-cyclohexyl-7-(6-dimethylamino-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine    Show/Hide	C26H27BrN6	1
1	IC50 > 1000 nM  Bioactivity Info	TI    LI    LO    TS

Compound ID	Compound Name	Compound Formula
CP0003832  Compound Info	N'-hydroxy-N-phenyloctanediamide    Show/Hide	C14H20N2O3	1
1	IC50 = 620 nM	TI    LI    LO    TS
CP0227869  Compound Info	3-methyl-1-[5-[4-(2-methylbutan-2-yl)phenoxy]pentyl]piperidine;oxalic acid    Show/Hide	C24H39NO5	1
1	IC50 = 30870 nM	TI    LI    LO    TS
CP0315357  Compound Info	3-methyl-1-(5-naphthalen-1-yloxypentyl)piperidine    Show/Hide	C21H29NO	1
1	IC50 = 32320 nM	TI    LI    LO    TS
CP0331699  Compound Info	1-(5-naphthalen-1-yloxypentyl)piperidine    Show/Hide	C20H27NO	1
1	IC50 > 50000 nM	TI    LI    LO    TS
CP0968036  Compound Info	4-(Dimethylamino)-N-(4-(hydroxycarbamoyl)benzyl)-N-(3-((4-methylbenzyl)amino)-3-oxopropyl)benzamide    Show/Hide	C28H32N4O4	1
1	IC50 = 260 nM	TI    LI    LO    TS

	Cell Line Name		Organism	Disease
	I3.4.2	Cell Line Info	Homo sapiens (Human)	Neuroblastoma