Brief Information of the Cell Line and Protein
Cell Line ID: CL000016 , IMR-32
 Cell Line Info 
Synonyms
IMR 32
IMR32
Institute for Medical Research-32
GM03320
GM3320C
GM03320D
AG03320
AG3320
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0346
Protein ID: PT02515 , Neuronal acetylcholine receptor subunit alpha-3
 Protein Info 
Gene Name CHRNA3
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID P32297
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000016
 Cell Line Info 
 Protein ID: PT02515
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0000212
 Compound Info 
()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane
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C11H13ClN2
  1
1
EC50 = 7 nM
 Bioactivity Info 
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CP0496090
 Compound Info 
2-Chloro-5-((R)-1-pyrrolidin-2-ylmethoxy)-pyridine
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C10H13ClN2O
  1
1
EC50 = 500 nM
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CP0004216
 Compound Info 
(S)-3-(azetidin-2-ylmethoxy)pyridine
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C9H12N2O
  1
1
EC50 = 700 nM
 Bioactivity Info 
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CP0304433
 Compound Info 
3-((R)-1-Azetidin-2-ylmethoxy)-pyridine
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C9H12N2O
  1
1
EC50 = 1100 nM
 Bioactivity Info 
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CP0399352
 Compound Info 
2-Chloro-5-((S)-1-pyrrolidin-2-ylmethoxy)-pyridine
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C10H13ClN2O
  1
1
EC50 = 1190 nM
 Bioactivity Info 
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CP0453429
 Compound Info 
2-Chloro-5-((S)-1-methyl-azetidin-2-ylmethoxy)-pyridine
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C10H13ClN2O
  1
1
EC50 = 28900 nM
 Bioactivity Info 
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CP0637450
 Compound Info 
(1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one
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C11H13BrN2O
  1
1
IC50 = 15.6 nM
 Bioactivity Info 
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CP0496691
 Compound Info 
3-benzoyl-4-bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C21H21BrN2O3
  1
1
IC50 = 1390 nM
 Bioactivity Info 
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CP0460435
 Compound Info 
4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C14H16BrClN2O2
  1
1
IC50 = 2090 nM
 Bioactivity Info 
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CP0398406
 Compound Info 
4-bromo-3-methylphenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C15H19BrN2O2
  1
1
IC50 = 4020 nM
 Bioactivity Info 
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CP0396962
 Compound Info 
3,4-dichlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C14H16Cl2N2O2
  1
1
IC50 = 4750 nM
 Bioactivity Info 
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CP0473866
 Compound Info 
naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C18H20N2O2
  1
1
IC50 = 4910 nM
 Bioactivity Info 
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CP0503928
 Compound Info 
4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C14H16ClFN2O2
  1
1
IC50 = 9960 nM
 Bioactivity Info 
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CP0407567
 Compound Info 
4-chlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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C14H17ClN2O2
  1
1
IC50 > 5000 nM
 Bioactivity Info 
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CP0047123
 Compound Info 
1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl carbamate
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C14H17BrN2O2
  1
1
IC50 > 6480 nM
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