Brief Information of the Compound and Protein
Compound Name
5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine
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PubChem ID
CID: 1973
SID: 14833946
Canonical SMILES
Nc1ncnc2nc(cc(-c3cccc(Br)c3)c12)-c1ccc(nc1)N1CCOCC1
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Compound Formula C22H19BrN6O
Compound Structure
Protein Name
Adenosine kinase
Protein Classification
Enzyme
Uniprot ID
P55263
Gene Name
ADK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.3 nM
2 IC50 = 1.7 nM
3 IC50 = 2 nM