General Information of the Compound
| Compound ID |
CP0495479
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| Compound Name |
5-(4-Bromo-thiophen-2-yl)-6-cyclopropyl-7-(6-dimethylamino-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine
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| Structure |
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| Formula |
C21H19BrN6S
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| Molecular Weight |
467.396
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| Canonical SMILES |
CN(C)c1ccc(cn1)-c1nc2ncnc(N)c2c(-c2cc(Br)cs2)c1C1CC1
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| InChI |
InChI=1S/C21H19BrN6S/c1-28(2)15-6-5-12(8-24-15)19-16(11-3-4-11)17(14-7-13(22)9-29-14)18-20(23)25-10-26-21(18)27-19/h5-11H,3-4H2,1-2H3,(H2,23,25,26,27)
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| InChIKey |
VLNWWFUSUIJISD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound