Brief Information of the Compound and Protein
Compound Name
6-Chloro-4-[1-(1-methyl-1H-indol-6-ylmethyl)-piperidin-4-ylamino]-chromen-2-one
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Canonical SMILES
Cn1ccc2ccc(CN3CCC(/N=c4\cc(O)oc5ccc(Cl)cc45)CC3)cc21
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Compound Formula C24H24ClN3O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  2
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
2
IC50 = 162 nM
   TI
   LI
   LO
   TS