Brief Information of the Compound and Protein
Compound Name
8-[1-[4-(2-methylpropyl)phenyl]pyrrolidin-3-yl]oxy-N-[[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methyl]quinolin-2-amine
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PubChem ID
CID: 44394826
Canonical SMILES
CC(C)Cc1ccc(cc1)N1CCC(C1)Oc1cccc2ccc(NCc3ccc(o3)-c3cccc(c3)C(F)(F)F)nc12
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Compound Formula C35H34F3N3O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000863 I3.4.2 Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS