Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-N-(1-((7-methoxybenzo[d][1,3]dioxol-5-yl)methyl)piperidin-4-yl)-1H-indazol-3-amine
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 PubChem ID
CID: 44405488
Canonical SMILES
COc1cc(CN2CCC(CC2)Nc2[nH]nc3ccc(Cl)cc23)cc2OCOc12
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Compound Formula C21H23ClN4O3
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS