Brief Information of the Compound and Protein
Compound Name
N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-2-[[(2R)-oxolan-2-yl]methylamino]pyridine-3-carboxamide
    Show/Hide
PubChem ID
CID: 44403528
Canonical SMILES
Clc1cnc(NC[C@H]2CCCO2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1
    Show/Hide
Compound Formula C24H29ClN4O4
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 50 nM
   TI
   LI
   LO
   TS