Brief Information of the Compound and Protein
Compound Name
6-chloro-1-methyl-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)-2-oxo-1,2-dihydroquinoline-3-carbonitrile
    Show/Hide
PubChem ID
CID: 44410944
Canonical SMILES
Cn1c2ccc(Cl)cc2c(NC2CCN(Cc3ccc4ccccc4c3)CC2)c(C#N)c1=O
    Show/Hide
Compound Formula C27H25ClN4O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  2
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
2
IC50 = 194 nM
   TI
   LI
   LO
   TS