| Compound ID |
Compound Name |
Compound Formula |
|
CP0160666
|
N-[2-(dimethylamino)ethyl]-N-methyl-4-[[4-[4-morpholin-4-yl-6-[(3S)-oxolan-3-yl]oxy-1,3,5-triazin-2-yl]phenyl]carbamoylamino]benzamide
Show/Hide
|
C30H38N8O5
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0108539
|
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Show/Hide
|
C32H41N9O4
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0341848
|
N-[2-(dimethylamino)ethyl]-4-[[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoylamino]-N-methylbenzamide
Show/Hide
|
C27H34N8O4
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0380703
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-8-(1H-pyrazol-4-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C19H18N6OS
|
1
|
| 1 |
IC50 < 0.5 nM
|
|
|
|
CP0380704
|
8-(azetidin-3-yl)-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C19H21N5OS
|
1
|
| 1 |
IC50 < 0.5 nM
|
|
|
|
CP0231518
|
N-[2-(dimethylamino)ethyl]-4-[[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoylamino]benzamide
Show/Hide
|
C26H32N8O4
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0282348
|
1-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3-[4-[4-morpholin-4-yl-6-(oxetan-3-yloxy)-1,3,5-triazin-2-yl]phenyl]urea
Show/Hide
|
C29H34N8O5
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0341849
|
4-[[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoylamino]-N-methyl-N-[2-(methylamino)ethyl]benzamide
Show/Hide
|
C26H32N8O4
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0044691
|
N-[2-(dimethylamino)ethyl]-N-methyl-4-[[4-(4-morpholin-4-yl-6-propan-2-yloxy-1,3,5-triazin-2-yl)phenyl]carbamoylamino]benzamide
Show/Hide
|
C29H38N8O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0044692
|
1-[4-[4-(dimethylamino)piperidine-1-carbonyl]phenyl]-3-[4-[4-morpholin-4-yl-6-[(3S)-oxolan-3-yl]oxy-1,3,5-triazin-2-yl]phenyl]urea
Show/Hide
|
C32H40N8O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0095286
|
1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo-[4,5-d]pyrimidin-5-yl)phenyl]-3-{4-[(4-methylpiperazin-1-yl)carbonyl]-phenyl}urea
Show/Hide
|
C29H34N10O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0231504
|
1-[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea
Show/Hide
|
C27H32N8O4
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0375072
|
8-(1-methylimidazol-4-yl)-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C20H20N6OS
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0409920
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole-8-carboxamide
Show/Hide
|
C17H17N5O2S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0231521
|
1-[4-(3,3-dimethylpiperazine-1-carbonyl)phenyl]-3-[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Show/Hide
|
C28H34N8O4
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0303113
|
4-[[4-[4-morpholin-4-yl-6-[(3S)-oxolan-3-yl]oxy-1,3,5-triazin-2-yl]phenyl]carbamoylamino]-N-(2-piperidin-1-ylethyl)benzamide
Show/Hide
|
C32H40N8O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0341850
|
4-[[4-[4-morpholin-4-yl-6-[(3S)-oxolan-3-yl]oxy-1,3,5-triazin-2-yl]phenyl]carbamoylamino]-N-(2-pyrrolidin-1-ylethyl)benzamide
Show/Hide
|
C31H38N8O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0404178
|
5-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyridin-2-amine
Show/Hide
|
C21H20N6OS
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0468673
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-8-pyrrolidin-3-yl-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C20H23N5OS
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0281944
|
1-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3-[4-[4-morpholin-4-yl-6-[(3S)-oxolan-3-yl]oxy-1,3,5-triazin-2-yl]phenyl]urea
Show/Hide
|
C30H36N8O5
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0313931
|
4-[[4-(4-methoxy-6-morpholin-4-yl-1,3,5-triazin-2-yl)phenyl]carbamoylamino]-N-(2-piperidin-1-ylethyl)benzamide
Show/Hide
|
C29H36N8O4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0375073
|
8-(1H-imidazol-2-yl)-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C19H18N6OS
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0376489
|
8-piperidin-4-yl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0404180
|
[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]methanol
Show/Hide
|
C17H18N4O2S
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0007893
|
4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
Show/Hide
|
C23H27N7O3S2
|
3
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
Ki = 2.6 nM
|
|
|
| 3 |
Ki = 10.2 nM
|
|
|
|
CP0515618
|
3-{6-[(dimethylamino)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}phenol
Show/Hide
|
C19H22N4O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0303112
|
1-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3-[4-(4-morpholin-4-yl-6-propan-2-yloxy-1,3,5-triazin-2-yl)phenyl]urea
Show/Hide
|
C29H36N8O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0345631
|
N-[2-(dimethylamino)ethyl]-4-[[4-(4-morpholin-4-yl-6-propan-2-yloxy-1,3,5-triazin-2-yl)phenyl]carbamoylamino]benzamide
Show/Hide
|
C28H36N8O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0090561
|
N-[2-chloro-5-(3-morpholin-4-ylquinoxalin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H19ClFN5O3S
|
2
|
| 1 |
IC50 = 3.1 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
|
CP0456044
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0272045
|
4-[[4-[4-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy]-6-morpholin-4-yl-1,3,5-triazin-2-yl]phenyl]carbamoylamino]benzamide
Show/Hide
|
C29H34N8O4
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0524072
|
N-methyl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole-8-carboxamide
Show/Hide
|
C18H19N5O2S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0529637
|
N-methyl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-9-carboxamide
Show/Hide
|
C18H20N6O2
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0380449
|
2-[[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]methylamino]ethanol
Show/Hide
|
C19H23N5O2S
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0375576
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0522831
|
3-(6-{[(2-methoxyethyl)(methyl)amino]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl)phenol
Show/Hide
|
C21H26N4O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0333717
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydrothieno[3,2-d][1]benzoxepine-8-carboxamide
Show/Hide
|
C18H18N4O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0090562
|
N-[2-chloro-5-[4-[4-(pyridin-4-ylmethyl)piperazin-1-yl]quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C30H26ClFN6O2S
|
2
|
| 1 |
IC50 = 4.6 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0252844
|
N-[2-chloro-5-(4-morpholin-4-ylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C24H20ClFN4O3S
|
2
|
| 1 |
IC50 = 4.6 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
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CP0380434
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-8-pyrrolidin-2-yl-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C20H23N5OS
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0210324
|
N-[2-chloro-5-(4-pyridin-3-ylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C25H16ClFN4O2S
|
2
|
| 1 |
IC50 = 5.4 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0298054
|
N-[2-chloro-5-[3-(4-propan-2-ylpiperazin-1-yl)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C26H26ClFN6O2S
|
2
|
| 1 |
IC50 = 5.4 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
|
CP0351967
|
5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)benzene-1,3-diol
Show/Hide
|
C19H16N4O4
|
4
|
| 1 |
IC50 = 5.9 nM
|
|
|
| 2 |
IC50 = 53.4 nM
|
|
|
| 3 |
IC50 = 61.3 nM
|
|
|
| 4 |
IC50 = 139.8 nM
|
|
|
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CP0547141
|
3-[6-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl]phenol
Show/Hide
|
C17H17N3O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0380436
|
1-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]ethane-1,2-diol
Show/Hide
|
C18H20N4O3S
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0152367
|
N-[2-chloro-5-(4-pyridin-4-ylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C25H16ClFN4O2S
|
2
|
| 1 |
IC50 = 6.5 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
|
CP0509990
|
3-(6-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl)phenol
Show/Hide
|
C23H29N5O3S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0245774
|
3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol
Show/Hide
|
C16H15N3O2S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0460277
|
3-{6-[(4-methylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}phenol
Show/Hide
|
C22H27N5O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0409919
|
N-[[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]methyl]acetamide
Show/Hide
|
C19H21N5O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0020505
|
(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0^{2,10}.0^{5,9}.0^{15,19}]nonadeca-2(10),12(19),14-trien-3-yl acetate
Show/Hide
|
C23H24O8
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0252843
|
N-[2-chloro-5-[3-(2-morpholin-4-ylethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C25H24ClFN6O3S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
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CP0376488
|
3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]-1H-pyridin-2-one
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0303297
|
1-[4-(4-methylpiperazine-1-carbonyl)phenyl]-3-[4-(4-morpholin-4-yl-6-oxo-1H-1,3,5-triazin-2-yl)phenyl]urea
Show/Hide
|
C26H30N8O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0013755
|
3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol
Show/Hide
|
C19H16N4O3
|
4
|
| 1 |
IC50 = 17.9 nM
|
|
|
| 2 |
IC50 = 74 nM
|
|
|
| 3 |
IC50 = 796.3 nM
|
|
|
| 4 |
IC50 = 1034.4 nM
|
|
|
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CP0519360
|
3-amino-5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 = 20.6 nM
|
|
|
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CP0474404
|
3-[7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl]phenol
Show/Hide
|
C17H17N3O2S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
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CP0468710
|
9-chloro-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydro-[1,2,4]triazolo[1,5-d][1,4]benzoxazepine
Show/Hide
|
C15H15ClN6O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
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CP0453880
|
5-[3-[4-[3-(4-methoxyphenyl)pyrazin-2-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
Show/Hide
|
C25H25N7O3S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0487285
|
3-fluoro-5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Show/Hide
|
C19H15FN4O3
|
1
|
| 1 |
IC50 = 40.9 nM
|
|
|
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CP0415534
|
4-[2-(1H-indazol-4-yl)-6-[(4-methylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
Show/Hide
|
C23H27N7OS
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0467053
|
2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-c]pyrazole
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0522306
|
(4aS,11cS)-9,10-Dihydroxy-4,4,11c-trimethyl-1,2,3,4,4a,5,6,11c-octahydro-benzo[b]naphtho[1,2-d]furan-8-carbaldehyde
Show/Hide
|
C20H24O4
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0426527
|
2-[2-(4-bromo-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C18H19BrN4O3
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0134138
|
2-[2-(4-chloro-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C18H19ClN4O3
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0456950
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3-amino-6-[4-chloro-3-[(3-chlorophenyl)sulfonylamino]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15Cl2N5O3S
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1
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| 1 |
IC50 = 90 nM
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CP0488589
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3-amino-6-(4-chloro-3-sulfamoylphenyl)-N-methylpyrazine-2-carboxamide
Show/Hide
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C12H12ClN5O3S
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1
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| 1 |
IC50 = 97 nM
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CP0265356
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(4aS,7R,12cS)-10,11-Dihydroxy-4,4,7,12c-tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulene-9-carbaldehyde
Show/Hide
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C22H28O4
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1
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| 1 |
IC50 = 100 nM
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CP0300568
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4-[2-(1H-indazol-4-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine
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C17H15N5OS
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1
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| 1 |
IC50 = 102 nM
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CP0533679
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5-[2-amino-4-(2,2,2-trifluoroethoxy)pyrimidin-5-yl]-2-chloro-N-(2,3-difluorophenyl)benzenesulfonamide
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C18H12ClF5N4O3S
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1
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| 1 |
IC50 = 110 nM
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CP0431538
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2-[2-(4-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 138 nM
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CP0525766
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2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1,2,4]triazolo[5,1-d][1,5]benzoxazepine
Show/Hide
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C15H16N6O
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1
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| 1 |
IC50 = 140 nM
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CP0413763
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3-amino-6-[4-chloro-3-[(4-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15Cl2N5O3S
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1
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| 1 |
IC50 = 142 nM
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CP0525817
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3-amino-6-[4-chloro-3-(methylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C13H14ClN5O3S
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1
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| 1 |
IC50 = 142 nM
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CP0433674
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3-amino-6-[4-chloro-3-[(3-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15Cl2N5O3S
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1
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| 1 |
IC50 = 174 nM
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CP0455223
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3-amino-6-[4-chloro-3-(phenylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H16ClN5O3S
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1
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| 1 |
IC50 = 174 nM
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CP0433670
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3-amino-6-[6-amino-5-(phenylsulfamoyl)pyridin-3-yl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C17H17N7O3S
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1
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| 1 |
IC50 = 200 nM
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CP0456951
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3-amino-6-[4-chloro-3-[(2-chloro-4-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H14Cl2FN5O3S
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1
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| 1 |
IC50 = 209 nM
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CP0134137
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4-morpholin-4-yl-2-[2-oxo-2-(4-phenyl-2,3-dihydroindol-1-yl)ethyl]-1H-pyrimidin-6-one
Show/Hide
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C24H24N4O3
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1
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| 1 |
IC50 = 217 nM
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CP0481681
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5-[3-[4-[2-(4-propan-2-ylphenyl)pyridin-3-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
Show/Hide
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C28H30N6O2S
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1
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| 1 |
IC50 = 220 nM
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CP0455221
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5-(2-amino-4-methoxypyrimidin-5-yl)-2-chloro-N-(2,3-difluorophenyl)benzenesulfonamide
Show/Hide
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C17H13ClF2N4O3S
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1
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| 1 |
IC50 = 234 nM
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CP0413761
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3-amino-6-[4-chloro-3-[(3-methoxyphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C19H18ClN5O4S
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1
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| 1 |
IC50 = 290 nM
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CP0262695
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2-[(1-methyl-4-phenylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O2
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1
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| 1 |
IC50 = 314 nM
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CP0456942
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3-amino-6-[4-chloro-3-[(3-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15ClFN5O3S
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1
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| 1 |
IC50 = 316 nM
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CP0450213
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2-[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 322 nM
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CP0381347
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3-amino-6-[4-chloro-3-[(2,4-dichlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H14Cl3N5O3S
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1
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| 1 |
IC50 = 323 nM
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CP0413764
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3-amino-6-[4-chloro-3-[(3-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C19H18ClN5O3S
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1
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| 1 |
IC50 = 323 nM
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CP0020253
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3-amino-6-[4-chloro-3-[(3-fluoro-2-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C19H17ClFN5O3S
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1
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| 1 |
IC50 = 342 nM
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CP0380836
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9-[(4-methoxyanilino)methyl]-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O3
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1
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| 1 |
IC50 = 350 nM
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CP0338973
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4-morpholin-4-yl-2-[2-oxo-2-(4-pyridin-3-yl-2,3-dihydroindol-1-yl)ethyl]-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O3
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1
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| 1 |
IC50 = 361 nM
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CP0308576
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4-morpholin-4-yl-2-[2-oxo-2-[4-(trifluoromethyl)-2,3-dihydroindol-1-yl]ethyl]-1H-pyrimidin-6-one
Show/Hide
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C19H19F3N4O3
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1
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| 1 |
IC50 = 390 nM
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CP0891904
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7-Methyl-9-[(3-methylbenzyl)amino]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 400 nM
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CP0375077
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N-methyl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydropyrazolo[1,5-d][1,4]benzoxazepine-9-carboxamide
Show/Hide
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C18H20N6O2
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1
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| 1 |
IC50 = 426 nM
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CP0155508
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2-[2-(5-fluoro-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C18H19FN4O3
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1
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| 1 |
IC50 = 426 nM
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CP0027760
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3-amino-6-[4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H14ClF2N5O3S
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1
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| 1 |
IC50 = 435 nM
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CP0735509
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4-Amino-6-(((1S)-1-(4-((1,1-dioxido-4-thiomorpholinyl)carbonyl)-6-fluoro-3-phenyl-2-quinolinyl)ethyl)amino)-5-pyrimidinecarbonitrile
Show/Hide
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C27H24FN7O3S
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1
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| 1 |
IC50 = 444 nM
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CP0180687
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2-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C18H20N4O3
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1
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| 1 |
IC50 = 460 nM
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CP0413762
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3-amino-6-[4-chloro-3-[(2-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15Cl2N5O3S
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1
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| 1 |
IC50 = 476 nM
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CP0877287
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2-(4-Morpholinyl)-4-oxo-N-phenyl-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C19H18N4O3
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1
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| 1 |
IC50 = 490 nM
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CP0848714
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9-(Benzylamino)-7-methyl-2-(4-morpholinyl)-4H-pyrido-[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 500 nM
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CP0381346
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5-[3-[4-[3-(4-propan-2-ylphenyl)pyrazin-2-yl]piperazin-1-yl]sulfonylphenyl]pyrimidin-2-amine
Show/Hide
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C27H29N7O2S
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1
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| 1 |
IC50 = 505 nM
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CP0852664
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N-[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzamide
Show/Hide
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C19H18N4O3
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1
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| 1 |
IC50 = 510 nM
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CP0456945
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3-amino-N-methyl-6-[3-(2H-tetrazol-5-yl)phenyl]pyrazine-2-carboxamide
Show/Hide
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C13H12N8O
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1
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| 1 |
IC50 = 529 nM
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CP0002420
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2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Show/Hide
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C19H17NO3
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1
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| 1 |
IC50 = 550 nM
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CP0456948
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3-amino-6-[4-chloro-3-[(2,3-dichlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H14Cl3N5O3S
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1
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| 1 |
IC50 = 555 nM
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CP0704953
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2-{2-[(2R)-2-Methyl-2,3-dihydro-1H-indol-1-yl]-2-oxoethyl}-6-(morpholin-4-yl)-pyrimidin-4(3H)-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 569 nM
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CP0877285
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3-Methyl-N-[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzamide
Show/Hide
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C20H20N4O3
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1
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| 1 |
IC50 = 570 nM
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CP0859324
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N-[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]-N'-phenylurea
Show/Hide
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C19H19N5O3
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1
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| 1 |
IC50 = 600 nM
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CP0688695
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7-methyl-9-(2-methylbenzylamino)-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 640 nM
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CP0379787
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2-[2-[4-[(4-methylpiperazin-1-yl)methyl]-2,3-dihydroindol-1-yl]-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C24H32N6O3
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1
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| 1 |
IC50 = 660 nM
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CP0508770
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(4'S,6R)-6'-bromo-2,2,4',6-tetramethyl-3',4'-dihydro-2'H-spiro[cyclohexane-1,1'-dibenzo[b,d]furan]-7',8'-diol
Show/Hide
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C21H27BrO3
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1
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| 1 |
IC50 = 700 nM
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CP0529072
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(4aS,11cS)-9,10-Dihydroxy-4,4,11c-trimethyl-1,2,3,4,4a,5,6,11c-octahydro-benzo[b]naphtho[1,2-d]furan-8-carboxylic acid amide
Show/Hide
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C20H25NO4
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1
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| 1 |
IC50 = 700 nM
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CP0705621
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2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N,N-dimethyl-3-phenyl-4-quinolinecarboxamide
Show/Hide
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C25H22FN7O
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1
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| 1 |
IC50 = 703 nM
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CP0381386
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3-amino-6-[3-[(3-chlorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H16ClN5O3S
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1
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| 1 |
IC50 = 705 nM
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CP0484882
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3-amino-6-[4-chloro-3-[[3-(trifluoromethyl)phenyl]sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C19H15ClF3N5O3S
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1
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| 1 |
IC50 = 727 nM
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CP0456949
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3-amino-N-methyl-6-[3-(phenylsulfamoyl)phenyl]pyrazine-2-carboxamide
Show/Hide
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C18H17N5O3S
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1
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| 1 |
IC50 = 744 nM
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CP0455222
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3-amino-6-[4-chloro-3-(2,2,2-trifluoroethylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C14H13ClF3N5O3S
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1
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| 1 |
IC50 = 752 nM
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CP0852663
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9-[(Methylanilino)methyl]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 790 nM
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CP0885989
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2-Methyl-N-[2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzamide
Show/Hide
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C20H20N4O3
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1
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| 1 |
IC50 = 810 nM
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CP0849180
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N-(3-Methylphenyl)-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C20H20N4O3
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1
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| 1 |
IC50 = 850 nM
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CP0910669
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7-Methyl-9-[(4-methylbenzyl)amino]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 900 nM
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CP0763406
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4-Amino-6-(((1S)-1-(6-fluoro-3-phenyl-4-(1-piperazinylcarbonyl)-2-quinolinyl)ethyl)amino)-5-pyrimidinecarbonitrile
Show/Hide
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C27H25FN8O
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1
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| 1 |
IC50 = 949 nM
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CP0456946
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3-amino-6-[4-fluoro-3-(phenylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H16FN5O3S
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1
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| 1 |
IC50 = 953 nM
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CP0453879
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2-(4-methoxyphenyl)-3-[4-[3-(4-methoxyphenyl)phenyl]sulfonylpiperazin-1-yl]pyrazine
Show/Hide
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C28H28N4O4S
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1
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| 1 |
IC50 = 960 nM
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CP0402567
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2-[2-[4-(4-methylpiperazin-1-yl)-2,3-dihydroindol-1-yl]-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H30N6O3
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1
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| 1 |
IC50 = 960 nM
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CP0484883
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3-amino-6-[4-chloro-3-[(2-chloro-3-fluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H14Cl2FN5O3S
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1
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| 1 |
IC50 = 972 nM
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CP0430032
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3-chloro-5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Show/Hide
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C19H15ClN4O3
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1
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| 1 |
IC50 = 990 nM
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CP0508774
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(4aS,11cS)-9-Hydroxy-10-methoxy-4,4,11c-trimethyl-1,2,3,4,4a,5,6,11c-octahydro-benzo[b]naphtho[1,2-d]furan-8-carbaldehyde
Show/Hide
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C21H26O4
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1
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| 1 |
IC50 = 1000 nM
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CP0362462
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2-[(1-ethylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C18H21N5O2
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1
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| 1 |
IC50 = 1000 nM
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CP0147576
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4-morpholin-4-yl-2-[2-oxo-2-(4-pyridin-4-yl-2,3-dihydroindol-1-yl)ethyl]-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0308575
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4-morpholin-4-yl-2-[2-oxo-2-[4-(trifluoromethoxy)-2,3-dihydroindol-1-yl]ethyl]-1H-pyrimidin-6-one
Show/Hide
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C19H19F3N4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0003061
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9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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3
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| 1 |
IC50 = 1000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
IC50 = 10000 nM
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CP0448986
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9-[(3-methylanilino)methyl]-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 1100 nM
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CP0859323
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9-(Anilinomethyl)-2-(4-morpholinyl)-4H-pyrido[1,2-a]-pyrimidin-4-one
Show/Hide
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C19H20N4O2
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1
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| 1 |
IC50 = 1100 nM
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CP0891905
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N-(4-Methylphenyl)-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
|
C20H20N4O3
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1
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| 1 |
IC50 = 1200 nM
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CP0487284
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3-bromo-5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Show/Hide
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C19H15BrN4O3
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1
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| 1 |
IC50 = 1210 nM
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CP0865509
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4-Methyl-N-[2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzamide
Show/Hide
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C20H20N4O3
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1
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| 1 |
IC50 = 1360 nM
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CP0848713
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7-Methyl-2-(4-morpholinyl)-9-(2-methylphenyl)-4Hpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 1500 nM
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CP0849182
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(Rac)-7-Methyl-9-[1-(methylanilino)ethyl]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C22H26N4O2
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1
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| 1 |
IC50 = 1500 nM
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CP0849236
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2-morpholino-9-(phenylthiomethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C19H19N3O2S
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1
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| 1 |
IC50 = 1500 nM
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CP0865510
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2-(4-Morpholinyl)-9-(phenoxymethyl)-4H-pyrido[1,2-a]-pyrimidin-4-one
Show/Hide
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C19H19N3O3
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1
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| 1 |
IC50 = 1500 nM
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CP0698887
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2-{2-[(2S)-2-Methyl-2,3-dihydro-1H-indol-1-yl]-2-oxoethyl}-6-(morpholin-4-yl)pyrimidin-4(3H)-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 1539 nM
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CP0852658
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9-[(4-Methoxyphenoxy)methyl]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H21N3O4
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1
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| 1 |
IC50 = 1600 nM
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CP0847737
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(4aS,11cS)-6a,10-Dihydroxy-4,4,11c-trimethyl-1,3,4,4a,5,6,6a,11c-octahydro-2H-benzo[b]naphtho[1,2-d]furan-9-one
Show/Hide
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C19H24O4
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1
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| 1 |
IC50 = 1650 nM
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CP0453878
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5-(2-aminopyrimidin-5-yl)-2-chloro-N-(2,3-difluorophenyl)benzenesulfonamide
Show/Hide
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C16H11ClF2N4O2S
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1
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| 1 |
IC50 = 1663 nM
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CP0866918
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9-Anilino-7-methyl-2-(4-morpholinyl)-4H-pyrido[1,2-a]-pyrimidin-4-one
Show/Hide
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C19H20N4O2
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1
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| 1 |
IC50 = 1700 nM
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CP0859065
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N-(2-Methylphenyl)-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C20H20N4O3
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1
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| 1 |
IC50 = 1800 nM
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CP0889364
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2-(4-Morpholinyl)-9-(2-toluidinomethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 1800 nM
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CP0456947
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3-amino-6-[4-methoxy-3-(phenylsulfamoyl)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C19H19N5O4S
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1
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| 1 |
IC50 = 1807 nM
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CP0910670
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7-Methyl-2-(4-morpholinyl)-9-[(2-pyridinylmethyl)amino]-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C19H21N5O2
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1
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| 1 |
IC50 = 2000 nM
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CP0308577
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2-[2-(5-chloro-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C18H19ClN4O3
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1
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| 1 |
IC50 = 2020 nM
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CP0186648
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2-(4-morpholin-4-yl-6-oxo-1H-pyrimidin-2-yl)-N-phenylacetamide
Show/Hide
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C16H18N4O3
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1
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| 1 |
IC50 = 2133 nM
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CP0508773
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(4aS,7S,12cS)-4,4,7,12c-Tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulen-10-ol
Show/Hide
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C21H28O2
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1
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| 1 |
IC50 = 2200 nM
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CP0889366
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7-Methyl-2-(4-morpholinyl)-9-{[(1S)-1-phenylethyl]amino}-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 2200 nM
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CP0308574
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2-[2-(3-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 2265 nM
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CP0453882
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3-amino-6-[3-[(2,3-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H15F2N5O3S
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1
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| 1 |
IC50 = 2369 nM
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CP0347349
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4-morpholin-4-yl-2-[2-oxo-2-(4-pyridin-2-yl-2,3-dihydroindol-1-yl)ethyl]-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O3
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1
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| 1 |
IC50 = 2375 nM
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CP0147577
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2-[2-(4-methoxy-2,3-dihydroindol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C19H22N4O4
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1
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| 1 |
IC50 = 2425 nM
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CP0460276
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4-[2-(1H-indazol-6-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine
Show/Hide
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C17H15N5OS
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1
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| 1 |
IC50 = 2450 nM
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CP0362492
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BDBM50447090
Show/Hide
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C18H19FN4O3
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1
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| 1 |
IC50 = 2450 nM
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CP0848712
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9-[(4-Methylphenoxy)methyl]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H21N3O3
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1
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| 1 |
IC50 = 2500 nM
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CP0852661
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7-Methyl-2-(4-morpholinyl)-9-{[(1R)-1-phenylethyl]amino}-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 2700 nM
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CP0525329
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N-methyl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[4,5-d][1,3]thiazole-8-carboxamide
Show/Hide
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C18H19N5O2S
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1
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| 1 |
IC50 = 2900 nM
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CP0859322
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7-Methyl-2-(4-morpholinyl)-9-(4-methylphenyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 2900 nM
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CP0484410
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9-[(4-chloroanilino)methyl]-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C19H19ClN4O2
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1
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| 1 |
IC50 = 3100 nM
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CP0921262
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(4aS,7R,12cS)-9-Bromo-7a,11-dihydroxy-4,4,7,12c-tetramethyl-1,2,3,4,4a,5,6,7,7a,12c-decahydro-8-oxa-dibenzo[a,h]azulen-10-one
Show/Hide
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C21H27BrO4
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1
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| 1 |
IC50 = 3300 nM
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CP0248388
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4-morpholin-4-yl-2-[(4-pyridin-2-yl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C21H19N5O3
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1
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| 1 |
IC50 = 3333 nM
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CP0413759
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3-amino-6-[3-[(3-chlorophenyl)sulfonylamino]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H16ClN5O3S
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1
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| 1 |
IC50 = 3381 nM
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CP0433672
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3-amino-N-methyl-6-[3-(trifluoromethyl)phenyl]pyrazine-2-carboxamide
Show/Hide
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C13H11F3N4O
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1
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| 1 |
IC50 = 3575 nM
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CP0455220
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3-amino-6-[3-(benzenesulfonamido)phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
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C18H17N5O3S
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1
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| 1 |
IC50 = 3643 nM
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CP0852660
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9-(2,6-Dimethylanilino)-7-methyl-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C21H24N4O2
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1
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| 1 |
IC50 = 3900 nM
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CP0176436
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2-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]-3-methyl-6-morpholin-4-ylpyrimidin-4-one
Show/Hide
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C19H22N4O3
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1
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| 1 |
IC50 = 4320 nM
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CP0169941
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4-morpholin-4-yl-2-[(4-thiophen-2-yl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C20H18N4O3S
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1
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| 1 |
IC50 = 4357 nM
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CP0891903
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7-Methyl-9-(methylanilino)-(4-morpholinyl)-4H-pyrido-[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 4400 nM
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CP0169945
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2-[(1-methyl-7-phenylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O2
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1
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| 1 |
IC50 = 4575 nM
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CP0456944
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5-(5-aminopyrazin-2-yl)-2-chloro-N-(2,3-difluorophenyl)benzenesulfonamide
Show/Hide
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C16H11ClF2N4O2S
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1
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| 1 |
IC50 = 4647 nM
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CP0919779
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2-(4-Morpholinyl)-4-oxo-N-(2-pyridinylmethyl)-4H-pyrido-[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C19H19N5O3
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1
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| 1 |
IC50 = 4800 nM
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CP0891906
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7-Methyl-2-(4-morpholinyl)-9-[(4-pyridinylmethyl)amino]-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C19H21N5O2
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1
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| 1 |
IC50 = 4900 nM
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CP0472463
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(4aS,11cS)-9,10-Dimethoxy-4,4,11c-trimethyl-1,2,3,4,4a,5,6,11c-octahydro-benzo[b]naphtho[1,2-d]furan-8-carbaldehyde
Show/Hide
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C22H28O4
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1
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| 1 |
IC50 = 5120 nM
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CP0134136
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BDBM50447097
Show/Hide
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C20H24N4O3
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1
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| 1 |
IC50 = 5421 nM
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CP0169946
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2-[(6-bromo-1H-benzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C16H16BrN5O2
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1
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| 1 |
IC50 = 5460 nM
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CP0253245
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4-morpholin-4-yl-2-[(4-phenyl-1H-benzimidazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C22H21N5O2
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1
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| 1 |
IC50 = 5503 nM
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CP0298910
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2-[(6-chloro-1H-benzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C16H16ClN5O2
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1
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| 1 |
IC50 = 5650 nM
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CP0147436
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2-[(1-benzylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O2
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1
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| 1 |
IC50 = 5725 nM
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CP0776506
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Rac-4-Amino-6-(1-(6-fluoro-4-(piperazine-1-carbonyl)-3-(pyridin-2-yl)quinolin-2-yl)ethylamino)pyrimidine-5-carbonitrile
Show/Hide
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C26H24FN9O
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1
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| 1 |
IC50 = 5750 nM
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CP0740357
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2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-3-phenyl-4-quinolinecarboxamide
Show/Hide
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C23H18FN7O
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1
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| 1 |
IC50 = 5760 nM
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CP0725929
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2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-N-ethyl-6-fluoro-3-phenyl-4-quinolinecarboxamide
Show/Hide
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C25H22FN7O
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1
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| 1 |
IC50 = 6230 nM
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CP0849237
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2-(4-Morpholinyl)-4-oxo-N-(4-pyridinylmethyl)-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C19H19N5O3
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1
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| 1 |
IC50 = 6400 nM
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CP0889365
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4-Methyl-N-{[2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]-pyrimidin-9-yl]methyl}benzenesulfonamide
Show/Hide
|
C20H22N4O4S
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1
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| 1 |
IC50 = 6500 nM
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CP0889367
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2-(4-Morpholinyl)-4-oxo-N-(3-pyridinylmethyl)-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
Show/Hide
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C19H19N5O3
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1
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| 1 |
IC50 = 6500 nM
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CP0188427
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4-morpholin-4-yl-2-[(1-phenylbenzimidazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C22H21N5O2
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1
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| 1 |
IC50 = 6790 nM
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CP0380835
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9-[(4-methylanilino)methyl]-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
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C20H22N4O2
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1
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| 1 |
IC50 = 6800 nM
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CP0303999
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2-[(7-methyl-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C17H18N4O3
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1
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| 1 |
IC50 = 7150 nM
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CP0494841
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(4aS,7R,12cS)-4,4,7,12c-Tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulen-11-ol
Show/Hide
|
C21H28O2
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1
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| 1 |
IC50 = 7200 nM
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CP0169944
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4-morpholin-4-yl-2-[(4-phenyl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C22H20N4O3
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1
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| 1 |
IC50 = 7754 nM
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CP0210357
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2-[(1-methyl-6-phenylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O2
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1
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| 1 |
IC50 = 7798 nM
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CP0053343
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4-amino-6-[[(1S)-1-(6-fluoro-3,4-dipyridin-2-ylquinolin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
Show/Hide
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C26H19FN8
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1
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| 1 |
IC50 = 7900 nM
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CP0204633
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2-[(1-cyclohexylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C22H27N5O2
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1
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| 1 |
IC50 = 8400 nM
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CP0852662
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Phenyl 2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-ylcarbamate
Show/Hide
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C19H18N4O4
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1
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| 1 |
IC50 = 9000 nM
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CP0322765
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2-[(6-methyl-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C17H18N4O3
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1
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| 1 |
IC50 = 9768 nM
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CP0341820
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2-[(6-methyl-1H-benzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C17H19N5O2
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1
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| 1 |
IC50 = 9880 nM
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CP0508771
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(4aS,7R,12cS)-9-Bromo-10-methoxy-4,4,7,12c-tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulene
Show/Hide
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C22H29BrO2
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1
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| 1 |
IC50 > 10000 nM
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CP0524644
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(4aS,7R,12cS)-4,4,7,12c-Tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulen-10-ol
Show/Hide
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C21H28O2
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1
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| 1 |
IC50 > 10000 nM
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CP0084873
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8-(1-anilinoethyl)-6-methyl-2-morpholin-4-ylchromen-4-one
Show/Hide
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C22H24N2O3
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1
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| 1 |
IC50 > 10000 nM
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CP0111428
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2-[(1-methylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C17H19N5O2
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
IC50 = 10000 nM
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CP0147434
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2-(1,3-benzoxazol-2-ylmethyl)-3-methyl-6-morpholin-4-ylpyrimidin-4-one
Show/Hide
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C17H18N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0169943
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4-morpholin-4-yl-2-[(7-phenyl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C22H20N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0169947
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2-[(6-fluoro-1H-benzimidazol-2-yl)methyl]-3-methyl-6-morpholin-4-ylpyrimidin-4-one
Show/Hide
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C17H18FN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0204632
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2-[(5-fluoro-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C16H15FN4O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0210358
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2-[(1-methyl-5-phenylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C23H23N5O2
|
1
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| 1 |
IC50 > 10000 nM
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CP0237639
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2-[(4-methyl-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H18N4O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0238398
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4-morpholin-4-yl-2-[(4-pyridin-4-yl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
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C21H19N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0248363
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2-[(5-fluoro-4-phenyl-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C22H19FN4O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0248389
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2-[(6-methoxy-1H-benzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H19N5O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0261386
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2-[(5-fluoro-1-methylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H18FN5O2
|
1
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| 1 |
IC50 > 10000 nM
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CP0295019
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2-(1,3-benzoxazol-2-ylmethyl)-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H16N4O3
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0295157
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2-[(7-fluoro-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H15FN4O3
|
1
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| 1 |
IC50 > 10000 nM
|
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CP0295159
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2-[[5-fluoro-1-(2-methoxyethyl)benzimidazol-2-yl]methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
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C19H22FN5O3
|
1
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| 1 |
IC50 > 10000 nM
|
|
|
|
CP0317536
|
2-[(5-methyl-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H18N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322764
|
4-morpholin-4-yl-2-[(4-pyridin-3-yl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-6-one
Show/Hide
|
C21H19N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322766
|
2-[(6-fluoro-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H15FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322767
|
2-[(4-fluoro-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H15FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322768
|
2-[(1-cyclopropyl-5-fluorobenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C19H20FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322769
|
2-[(6-fluoro-1H-benzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H16FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0341818
|
2-[(4-bromo-1,3-benzoxazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H15BrN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0341819
|
4-morpholin-4-yl-2-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]-1H-pyrimidin-6-one
Show/Hide
|
C17H16F3N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0341821
|
2-[(6-fluoro-1-methylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C17H18FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0362464
|
2-(1H-benzimidazol-2-ylmethyl)-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C16H17N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0439702
|
8-(4-fluoro-2-methylphenoxy)-2-morpholin-4-yl-1H-quinolin-4-one
Show/Hide
|
C20H19FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0458589
|
3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)-5-nitrophenol
Show/Hide
|
C19H15N5O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0462253
|
3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)-5-(trifluoromethyl)phenol
Show/Hide
|
C20H15F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487283
|
3-methyl-5-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Show/Hide
|
C20H18N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379786
|
2-[2-(2,2-dimethyl-3H-indol-1-yl)-2-oxoethyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852659
|
4-{[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]methoxy}benzonitrile
Show/Hide
|
C20H18N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0852665
|
N-[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzenesulfonamide
Show/Hide
|
C18H18N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0908314
|
2-(4-Morpholinyl)-9-[(phenylsulfonyl)methyl]-4H-pyrido-[1,2-a]pyrimidin-4-one
Show/Hide
|
C19H19N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0908315
|
7-Methyl-2-(4-morpholinyl)-9-[(3-pyridinylmethyl)amino]-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508772
|
(4aS,7R,12cS)-9-Bromo-4,4,7,12c-tetramethyl-2,3,4,4a,5,6,7,12c-octahydro-1H-8-oxa-dibenzo[a,h]azulen-10-ol
Show/Hide
|
C21H27BrO2
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0830604
|
Rac-4-Amino-6-(1-(6-fluoro-4-(3-hydroxyazetidine-1-carbonyl)-3-(pyridin-2-yl)quinolin-2-yl)ethylamino)pyrimidine-5-carbonitrile
Show/Hide
|
C25H21FN8O2
|
1
|
| 1 |
IC50 = 10900 nM
|
|
|
|
CP0720960
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-phenyl-4-quinolinecarboxamide
Show/Hide
|
C24H20FN7O
|
1
|
| 1 |
IC50 = 12600 nM
|
|
|
|
CP0698893
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-(1-methylethyl)-3-phenyl-4-quinolinecarboxamide
Show/Hide
|
C26H24FN7O
|
1
|
| 1 |
IC50 = 12700 nM
|
|
|
|
CP0735511
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide
Show/Hide
|
C23H19FN8O
|
1
|
| 1 |
IC50 = 14180 nM
|
|
|
|
CP0698894
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-N-ethyl-6-fluoro-3-(2-pyridinyl)-4-quinolinecarboxamide
Show/Hide
|
C24H21FN8O
|
1
|
| 1 |
IC50 = 16800 nM
|
|
|
|
CP0830605
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide
Show/Hide
|
C23H19FN8O
|
1
|
| 1 |
IC50 = 17600 nM
|
|
|
|
CP0720957
|
2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-N-(2-(dimethylamino)ethyl)-6-fluoro-3-(2-pyridinyl)-4-quinolinecarboxamide
Show/Hide
|
C25H24FN9O
|
1
|
| 1 |
IC50 = 29200 nM
|
|
|
|
CP0720958
|
AMG319
Show/Hide
|
C21H16FN7
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0908317
|
7-Methyl-2-(4-morpholinyl)-9-(3-methylphenyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0376485
|
2-[4-[2-(5-amino-2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]ethanol
Show/Hide
|
C21H23N7O2S
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0408161
|
8-[1-(methylsulfonylmethyl)pyrazol-4-yl]-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazole
Show/Hide
|
C21H22N6O3S2
|
1
|
| 1 |
Ki = 0.06 nM
|
|
|
|
CP0409918
|
2-[4-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]ethanamine
Show/Hide
|
C21H23N7OS
|
1
|
| 1 |
Ki = 0.06 nM
|
|
|
|
CP0409917
|
2-methyl-2-[4-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]propanamide
Show/Hide
|
C23H25N7O2S
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0380433
|
1-[4-[2-(5-amino-2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]-2-methylpropan-2-ol
Show/Hide
|
C23H27N7O2S
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0376487
|
2-methyl-1-[4-[2-[2-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]propan-2-ol
Show/Hide
|
C22H21F3N6O2S
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0408162
|
2-methyl-1-[4-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]propan-2-ol
Show/Hide
|
C23H26N6O2S
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0456045
|
2-[4-[2-(5-methyl-2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]ethanol
Show/Hide
|
C22H24N6O2S
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0525331
|
3-[8-[1-(2-hydroxy-2-methylpropyl)pyrazol-4-yl]-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-2-yl]-4-propan-2-yl-1H-1,2,4-triazol-5-one
Show/Hide
|
C23H26N6O3S
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0085320
|
2-[4-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]pyrazol-1-yl]ethanol
Show/Hide
|
C21H22N6O2S
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0376486
|
2-methyl-2-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]propanamide
Show/Hide
|
C23H28N6O2S
|
1
|
| 1 |
Ki = 0.47 nM
|
|
|
|
CP0476557
|
N-[2-chloro-5-[3-(4,4-difluoropiperidin-1-yl)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C24H19ClF3N5O2S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0375069
|
2-hydroxy-1-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]ethanone
Show/Hide
|
C21H23N5O3S
|
1
|
| 1 |
Ki = 0.61 nM
|
|
|
|
CP0380701
|
(2S)-3-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]propane-1,2-diol
Show/Hide
|
C22H27N5O3S
|
1
|
| 1 |
Ki = 0.69 nM
|
|
|
|
CP0391659
|
N-[2-chloro-5-[4-[4-(dimethylamino)phenyl]quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C28H22ClFN4O2S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0399396
|
N-[2-chloro-5-[3-(cyclohexylmethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C26H25ClFN5O2S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0495442
|
N-[2-chloro-5-[3-(2-phenylethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C27H21ClFN5O2S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0390761
|
N-[2-chloro-5-[4-(4-hydroxypiperidin-1-yl)quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C25H22ClFN4O3S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0431313
|
N-[2-chloro-5-[3-(2-methoxyethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C22H19ClFN5O3S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0461919
|
N-[2-chloro-5-(3-piperidin-1-ylquinoxalin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C24H21ClFN5O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0468709
|
2-methyl-1-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]propan-2-ol
Show/Hide
|
C23H29N5O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0408180
|
2-amino-2-methyl-1-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]propan-1-one
Show/Hide
|
C23H28N6O2S
|
1
|
| 1 |
Ki = 0.94 nM
|
|
|
|
CP0199316
|
N-[6-[5-[(4-tert-butylphenyl)sulfonylamino]-6-chloropyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C24H23ClN4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0216915
|
N-[6-[6-chloro-5-[[3-(trifluoromethyl)phenyl]sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H14ClF3N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0216916
|
N-[6-[6-chloro-5-[(3-chlorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14Cl2N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0242028
|
N-[6-[6-chloro-5-[(2-chlorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14Cl2N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0287443
|
N-[6-[6-chloro-5-[[2-(trifluoromethyl)phenyl]sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H14ClF3N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0294229
|
N-[6-[6-chloro-5-[(2-fluorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14ClFN4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0313207
|
N-[6-[6-chloro-5-[(4-methoxyphenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H17ClN4O4S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0313209
|
N-[6-[6-chloro-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H14ClF3N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0313210
|
N-[6-[5-[(3-tert-butylphenyl)sulfonylamino]-6-chloropyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C24H23ClN4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0356126
|
N-[6-[6-chloro-5-[(4-chlorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14Cl2N4O3S2
|
1
|
| 1 |
Ki < 1 nM
|
|
|
|
CP0399013
|
N-[2-chloro-5-(3-pyridin-4-ylquinoxalin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C24H15ClFN5O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0431310
|
N-[5-[4-(4-benzylpiperazin-1-yl)quinolin-6-yl]-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C31H27ClFN5O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0461823
|
N-[5-[3-(3-azabicyclo[3.2.2]nonan-3-yl)quinoxalin-6-yl]-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C27H25ClFN5O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0533259
|
N-[2-chloro-5-[3-[2-methoxyethyl(methyl)amino]quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H21ClFN5O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0216917
|
N-[6-[6-chloro-5-[(3-fluorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14ClFN4O3S2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0199338
|
N-[6-[6-chloro-5-[(4-fluorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H14ClFN4O3S2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0356125
|
N-[6-[5-[(4-methoxyphenyl)sulfonylamino]-6-methylpyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C22H20N4O4S2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0475656
|
N-[2-chloro-5-(4-phenylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C26H17ClFN3O2S
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0313208
|
N-[6-[5-(benzenesulfonamido)-6-chloropyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H15ClN4O3S2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0356124
|
N-[6-[6-cyano-5-[(4-methoxyphenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C22H17N5O4S2
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1
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| 1 |
Ki = 1.4 nM
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CP0427666
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N-[2-chloro-5-[3-(4-methoxypiperidin-1-yl)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C25H23ClFN5O3S
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1
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| 1 |
Ki = 1.4 nM
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CP0505973
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N-[5-[3-[benzyl(methyl)amino]quinoxalin-6-yl]-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
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C27H21ClFN5O2S
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1
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| 1 |
Ki = 1.4 nM
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CP0313206
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N-[6-[5-[(4-methoxyphenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H18N4O4S2
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1
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| 1 |
Ki = 1.6 nM
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CP0431312
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N-[2-chloro-5-[3-(dimethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C21H17ClFN5O2S
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1
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| 1 |
Ki = 1.7 nM
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CP0399012
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N-[2-chloro-5-[4-(4-propan-2-ylpiperazin-1-yl)quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C27H27ClFN5O2S
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1
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| 1 |
Ki = 1.8 nM
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CP0461818
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N-[2-chloro-5-(4-piperidin-1-ylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C25H22ClFN4O2S
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1
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| 1 |
Ki = 1.9 nM
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CP0404177
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2-[3-[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-8-yl]azetidin-1-yl]ethanol
Show/Hide
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C21H25N5O2S
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1
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| 1 |
Ki = 1.9 nM
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CP0191328
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3-[[1-(4-methyl-1,3,5-triazin-2-yl)benzimidazol-2-yl]amino]phenol
Show/Hide
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C17H14N6O
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1
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| 1 |
Ki = 2 nM
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CP0387452
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N-(2-chloro-5-quinolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide
Show/Hide
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C20H13ClFN3O2S
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1
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| 1 |
Ki = 2.1 nM
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CP0491653
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N-(2-chloro-5-quinazolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide
Show/Hide
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C19H12ClFN4O2S
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1
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| 1 |
Ki = 2.6 nM
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CP0330594
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylphenyl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C23H23N7O3S
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1
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| 1 |
Ki = 3 nM
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CP0431311
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N-(2-chloro-5-quinoxalin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide
Show/Hide
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C19H12ClFN4O2S
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1
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| 1 |
Ki = 3.1 nM
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CP0491652
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N-[2-chloro-5-[3-(2-piperidin-1-ylethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C26H26ClFN6O2S
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1
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| 1 |
Ki = 3.1 nM
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CP0431314
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N-[2-chloro-5-[3-(piperidin-3-ylmethylamino)quinoxalin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C25H24ClFN6O2S
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1
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| 1 |
Ki = 3.3 nM
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CP0172054
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4-[5-(3,6-dihydro-2H-pyran-4-yl)-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C20H21N7O2
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1
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| 1 |
Ki = 5 nM
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CP0476558
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N-[2-chloro-5-(1,5-naphthyridin-2-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C19H12ClFN4O2S
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1
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| 1 |
Ki = 5.1 nM
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CP0295372
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N-[5-(2-amino-1,3-benzothiazol-6-yl)-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C18H12ClFN4O2S2
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1
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| 1 |
Ki = 5.6 nM
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CP0387479
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N-[2-chloro-5-[4-(dimethylamino)quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C22H18ClFN4O2S
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1
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| 1 |
Ki = 5.7 nM
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CP0191321
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(6-methylpyridin-3-yl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C21H20N8O
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1
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| 1 |
Ki = 8 nM
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CP0192152
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(1-methylpyrazol-4-yl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C19H19N9O
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1
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| 1 |
Ki = 8 nM
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CP0287442
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N-[6-[6-[(4-methoxyphenyl)sulfonylamino]pyrazin-2-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H17N5O4S2
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1
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| 1 |
Ki = 9 nM
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CP0009370
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylpiperazin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C21H27N9O3S
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1
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| 1 |
Ki = 9 nM
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CP0087634
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(1-methylsulfonylpiperidin-4-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C22H28N8O3S
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1
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| 1 |
Ki = 9 nM
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CP0284307
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3-[[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)pyridin-2-yl]amino]phenol
Show/Hide
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C15H14N6O
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1
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| 1 |
Ki = 12 nM
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CP0191632
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N-[5-(1,3-benzothiazol-6-yl)-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
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C18H11ClFN3O2S2
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1
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| 1 |
Ki = 12.9 nM
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CP0305666
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N-[6-[2-[(4-methoxyphenyl)sulfonylamino]pyridin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H18N4O4S2
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1
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| 1 |
Ki = 13 nM
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CP0087633
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(3-methylsulfonylpyrrolidin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C21H26N8O3S
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1
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| 1 |
Ki = 16 nM
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CP0142914
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2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-6-methyl-1,3,5-triazin-2-ylamino)acetonitrile
Show/Hide
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C19H16N8O
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1
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| 1 |
Ki = 16 nM
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CP0174686
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4-[[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methyl]-N,N-dimethylpiperazine-1-sulfonamide
Show/Hide
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C22H30N10O3S
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1
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| 1 |
Ki = 17 nM
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CP0305664
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N-[6-[2-(4-methoxyphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4O2S2
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1
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| 1 |
Ki = 18 nM
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CP0356118
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N-[6-[2-[(3-methoxyphenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H18N4O3S
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1
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| 1 |
Ki = 18 nM
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CP0338291
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylpiperidin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C22H28N8O3S
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1
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| 1 |
Ki = 22 nM
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CP0397436
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-morpholin-4-ylpyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C19H22N8O2
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1
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| 1 |
Ki = 22 nM
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CP0349370
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N-[6-[2-(2-phenylpropan-2-ylamino)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C22H21N5OS
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1
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| 1 |
Ki = 24 nM
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CP0087590
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3-[[3-(6-amino-2-methylpyrimidin-4-yl)pyridin-2-yl]amino]phenol
Show/Hide
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C16H15N5O
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1
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| 1 |
Ki = 28 nM
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CP0199313
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N-[6-[2-(3-fluorophenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H13FN4OS2
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1
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| 1 |
Ki = 31 nM
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CP0305663
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N-[6-[2-(2-methylphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4OS2
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1
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| 1 |
Ki = 31 nM
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CP0305665
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N-[6-[2-(3-phenylpropoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C22H20N4O2S
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1
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| 1 |
Ki = 32 nM
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CP0397437
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(4-methylsulfonyl-1,4-diazepan-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C22H29N9O3S
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1
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| 1 |
Ki = 33 nM
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CP0349449
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N-[6-[2-[methyl-(4-methylphenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H19N5O3S2
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1
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| 1 |
Ki = 38 nM
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CP0461822
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N-(2-chloro-5-cinnolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide
Show/Hide
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C19H12ClFN4O2S
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1
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| 1 |
Ki = 38 nM
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CP0282689
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N-[3-(2-methyl-7H-purin-6-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
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C18H14N8
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1
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| 1 |
Ki = 39 nM
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CP0391258
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(4-methylpiperazin-1-yl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C20H25N9O
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1
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| 1 |
Ki = 39 nM
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CP0199312
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N-[6-(2-phenylsulfanylpyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H14N4OS2
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1
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| 1 |
Ki = 40 nM
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CP0356122
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N-[6-[2-[(2-fluorophenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H14FN5O3S2
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1
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| 1 |
Ki = 41 nM
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CP0313204
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N-[6-[2-(4-fluorophenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H13FN4OS2
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1
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| 1 |
Ki = 44 nM
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CP0238872
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N-[6-[2-(2-fluorophenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H13FN4OS2
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1
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| 1 |
Ki = 46 nM
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CP0349368
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N-[6-[2-[(3-methylphenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H18N4O2S
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1
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| 1 |
Ki = 47 nM
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CP0356117
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N-[6-(2-benzylsulfanylpyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4OS2
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1
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| 1 |
Ki = 47 nM
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CP0238876
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N-[6-[3-[(4-methoxyphenyl)sulfonylamino]phenyl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C22H19N3O4S2
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1
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| 1 |
Ki = 48 nM
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CP0294227
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N-[6-[2-(3-methoxyphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4O2S2
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1
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| 1 |
Ki = 48 nM
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CP0191323
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4-[5-(methoxymethyl)-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C17H19N7O2
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1
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| 1 |
Ki = 49 nM
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CP0218935
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N-[6-(2-methylsulfanylpyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C14H12N4OS2
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1
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| 1 |
Ki = 53 nM
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CP0238873
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N-[6-[2-(3-methylphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4OS2
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1
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| 1 |
Ki = 53 nM
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CP0192153
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4-[5-methoxy-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C16H17N7O2
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1
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| 1 |
Ki = 55 nM
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CP0212254
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N-[6-[2-[(4-methoxyphenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H18N4O3S
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1
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| 1 |
Ki = 58 nM
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CP0242027
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N-[6-[2-[(4-methylphenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H18N4O2S
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1
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| 1 |
Ki = 58 nM
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CP0313205
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N-[6-[2-(4-methylphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4OS2
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1
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| 1 |
Ki = 59 nM
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CP0282688
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4-[5-benzyl-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C22H21N7O
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1
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| 1 |
Ki = 59 nM
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CP0242026
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N-[6-[2-[(3-fluorophenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H15FN4O2S
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1
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| 1 |
Ki = 61 nM
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CP0192150
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(piperazin-1-ylmethyl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C20H25N9O
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1
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| 1 |
Ki = 61 nM
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CP0142636
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N-[6-[2-[ethyl-(4-methoxyphenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C22H21N5O4S2
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1
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| 1 |
Ki = 62 nM
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CP0172047
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[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methanol
Show/Hide
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C16H17N7O2
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1
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| 1 |
Ki = 63 nM
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CP0356123
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N-[6-[2-[(2-fluorophenyl)sulfonyl-methylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16FN5O3S2
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1
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| 1 |
Ki = 65 nM
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CP0188464
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N-(6-methoxypyridin-3-yl)-3-(2-methyl-7H-purin-6-yl)pyridin-2-amine
Show/Hide
|
C17H15N7O
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1
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| 1 |
Ki = 67 nM
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CP0505974
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N-[2-chloro-5-[4-(2-methoxyethylamino)quinolin-6-yl]pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H20ClFN4O3S
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1
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| 1 |
Ki = 69 nM
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CP0191320
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4-[5-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C20H24N8O3S
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1
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| 1 |
Ki = 73 nM
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CP0294228
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N-[6-[2-[(4-methoxyphenyl)sulfonyl-methylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H19N5O4S2
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1
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| 1 |
Ki = 76 nM
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CP0212256
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N-[6-[2-[(4-methylphenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H17N5O3S2
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1
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| 1 |
Ki = 82 nM
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CP0199315
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N-[6-[2-[(3-fluorophenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H14FN5O3S2
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1
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| 1 |
Ki = 84 nM
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CP0335114
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4-[[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methyl]-N,N-dimethylpiperazine-1-carboxamide
Show/Hide
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C23H30N10O2
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1
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| 1 |
Ki = 84 nM
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CP0337419
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N-[6-[2-(benzylamino)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H17N5OS
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1
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| 1 |
Ki = 85 nM
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CP0143583
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N-[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
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C16H14N8
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1
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| 1 |
Ki = 92 nM
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CP0452207
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methyl 4-[[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methyl]piperazine-1-carboxylate
Show/Hide
|
C22H27N9O3
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1
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| 1 |
Ki = 94 nM
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CP0192151
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(morpholin-4-ylmethyl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C20H24N8O2
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1
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| 1 |
Ki = 100 nM
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CP0050169
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N-[6-(2-phenoxypyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C19H14N4O2S
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1
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| 1 |
Ki = 102 nM
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CP0212253
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N-[6-(2-phenylmethoxypyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4O2S
|
1
|
| 1 |
Ki = 105 nM
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CP0349679
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4-[2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C15H15N7O
|
1
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| 1 |
Ki = 110 nM
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CP0238875
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N-[6-[2-(3-pyridin-3-ylpropoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H19N5O2S
|
1
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| 1 |
Ki = 113 nM
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CP0199314
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N-[6-[2-(3-pyridin-4-ylpropoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C21H19N5O2S
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1
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| 1 |
Ki = 114 nM
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CP0349447
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N-[6-[2-[(4-methoxyphenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H17N5O4S2
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1
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| 1 |
Ki = 117 nM
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CP0076062
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4-[4-[(6-methoxypyridin-3-yl)amino]pyrimidin-5-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C14H14N8O
|
1
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| 1 |
Ki = 120 nM
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CP0139562
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6-[3-[(6-methoxypyridin-3-yl)amino]pyrazin-2-yl]-2-methylpyrimidin-4-amine
Show/Hide
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C15H15N7O
|
1
|
| 1 |
Ki = 120 nM
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CP0238874
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N-[6-[2-(pyridin-4-ylmethoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C19H15N5O2S
|
1
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| 1 |
Ki = 128 nM
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CP0356119
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N-[6-[2-[(4-fluorophenyl)methoxy]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H15FN4O2S
|
1
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| 1 |
Ki = 141 nM
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CP0242025
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N-[6-[2-(2-methoxyphenyl)sulfanylpyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H16N4O2S2
|
1
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| 1 |
Ki = 144 nM
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CP0142635
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N-[6-[2-(3-morpholin-4-ylpropoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
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C20H23N5O3S
|
1
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| 1 |
Ki = 148 nM
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CP0143584
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N-[3-(6-amino-2-methylpyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
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C17H15N7
|
1
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| 1 |
Ki = 150 nM
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CP0339164
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(piperidin-1-ylmethyl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C21H26N8O
|
1
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| 1 |
Ki = 150 nM
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CP0343352
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4-[5-(azetidin-1-ylmethyl)-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C19H22N8O
|
1
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| 1 |
Ki = 160 nM
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CP0302072
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N-[3-(2-methyl-7H-purin-6-yl)pyridin-2-yl]-1H-indol-4-amine
Show/Hide
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C19H15N7
|
1
|
| 1 |
Ki = 190 nM
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CP0387454
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N-[2-chloro-5-(1,7-naphthyridin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C19H12ClFN4O2S
|
1
|
| 1 |
Ki = 200 nM
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CP0087588
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1-[[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methyl]piperidin-4-ol
Show/Hide
|
C21H26N8O2
|
1
|
| 1 |
Ki = 200 nM
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CP0142948
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N-[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)pyridin-2-yl]-1H-indol-4-amine
Show/Hide
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C17H15N7
|
1
|
| 1 |
Ki = 200 nM
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CP0131195
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-methylpyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C16H17N7O
|
1
|
| 1 |
Ki = 240 nM
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CP0292692
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4-[5-bromo-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
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C15H14BrN7O
|
1
|
| 1 |
Ki = 250 nM
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CP0172042
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-[(4-methylpiperazin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C21H27N9O
|
1
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| 1 |
Ki = 260 nM
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CP0313976
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4-[2-[(6-methoxypyridin-3-yl)amino]-5-(pyrrolidin-1-ylmethyl)pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C20H24N8O
|
1
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| 1 |
Ki = 270 nM
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CP0087587
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[(3R)-1-[[5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]methyl]pyrrolidin-3-yl]methanol
Show/Hide
|
C21H26N8O2
|
1
|
| 1 |
Ki = 280 nM
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CP0191322
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4-[5-[(2-methoxyethylamino)methyl]-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C19H24N8O2
|
1
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| 1 |
Ki = 280 nM
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CP0369237
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4-[5-chloro-2-[(6-methoxypyridin-3-yl)amino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C15H14ClN7O
|
1
|
| 1 |
Ki = 290 nM
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CP0136329
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N-[6-[2-(3-methoxypropoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C17H18N4O3S
|
1
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| 1 |
Ki = 333 nM
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CP0050326
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2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazin-2-ylamino)acetonitrile
Show/Hide
|
C18H14N8O
|
1
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| 1 |
Ki = 350 nM
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CP0387453
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N-(2-chloro-5-isoquinolin-6-ylpyridin-3-yl)-4-fluorobenzenesulfonamide
Show/Hide
|
C20H13ClFN3O2S
|
1
|
| 1 |
Ki = 375 nM
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CP0064828
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4-[3-[(6-methoxypyridin-3-yl)amino]pyrazin-2-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C14H14N8O
|
1
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| 1 |
Ki = 520 nM
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CP0524479
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N-[6-(2-benzylpyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C20H16N4OS
|
1
|
| 1 |
Ki = 605 nM
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CP0328888
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4-[3-[(6-methoxypyridin-3-yl)amino]pyridin-4-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C15H15N7O
|
1
|
| 1 |
Ki = 620 nM
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CP0330553
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4-[2-[(6-methoxypyridin-3-yl)amino]phenyl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C16H16N6O
|
1
|
| 1 |
Ki = 640 nM
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CP0271829
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N-[6-[2-[(4-fluorophenyl)sulfonylamino]pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C19H14FN5O3S2
|
1
|
| 1 |
Ki = 826 nM
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CP0495427
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N-[2-chloro-5-(1,8-naphthyridin-3-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
Show/Hide
|
C19H12ClFN4O2S
|
1
|
| 1 |
Ki = 856 nM
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CP0346280
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N-[3-(6-amino-5-fluoro-2-methylpyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
|
C17H14FN7
|
1
|
| 1 |
Ki = 930 nM
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CP0037882
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N-[6-[2-(2-phenylethyl)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C21H18N4OS
|
1
|
| 1 |
Ki = 1010 nM
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CP0391261
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4-[3-[(6-methoxypyridin-3-yl)amino]pyridin-2-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C15H15N7O
|
1
|
| 1 |
Ki = 1300 nM
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CP0356120
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N-[6-[2-(2-morpholin-4-ylethoxy)pyrimidin-4-yl]-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C19H21N5O3S
|
1
|
| 1 |
Ki = 1550 nM
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CP0191327
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N-[3-(6-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
|
C18H14N8
|
1
|
| 1 |
Ki = 1700 nM
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CP0356121
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N-[4-(2-acetamido-1,3-benzothiazol-6-yl)pyrimidin-2-yl]-4-methoxybenzamide
Show/Hide
|
C21H17N5O3S
|
1
|
| 1 |
Ki = 3130 nM
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CP0174742
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N-[3-[6-amino-2-(trifluoromethyl)pyrimidin-4-yl]pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
|
C17H12F3N7
|
1
|
| 1 |
Ki = 3200 nM
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CP0335115
|
3-[[3-(2-amino-6-methylpyrimidin-4-yl)pyridin-2-yl]amino]phenol
Show/Hide
|
C16H15N5O
|
1
|
| 1 |
Ki = 4900 nM
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CP0305662
|
N-[6-(2-anilinopyrimidin-4-yl)-1,3-benzothiazol-2-yl]acetamide
Show/Hide
|
C19H15N5OS
|
1
|
| 1 |
Ki = 6100 nM
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CP0229154
|
N-(6-methoxypyridin-3-yl)-3-(7H-purin-6-yl)pyridin-2-amine
Show/Hide
|
C16H13N7O
|
1
|
| 1 |
Ki = 8300 nM
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CP0087589
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N-[3-(7H-purin-6-yl)pyridin-2-yl]-1H-indazol-4-amine
Show/Hide
|
C17H12N8
|
1
|
| 1 |
Ki > 10000 nM
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CP0356738
|
4-[2-[(6-methoxypyridin-3-yl)-methylamino]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine
Show/Hide
|
C16H17N7O
|
1
|
| 1 |
Ki > 10000 nM
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CP0356739
|
4-[2-(1H-indol-4-yloxy)pyridin-3-yl]-6-methylpyrimidin-2-amine
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
Ki > 10000 nM
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