General Information of the Compound
| Compound ID |
CP0908314
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| Compound Name |
2-(4-Morpholinyl)-9-[(phenylsulfonyl)methyl]-4H-pyrido-[1,2-a]pyrimidin-4-one
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| Structure |
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| Formula |
C19H19N3O4S
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| Molecular Weight |
385.445
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| Canonical SMILES |
O=c1cc(N2CCOCC2)nc2c(CS(=O)(=O)c3ccccc3)cccn12
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| InChI |
InChI=1S/C19H19N3O4S/c23-18-13-17(21-9-11-26-12-10-21)20-19-15(5-4-8-22(18)19)14-27(24,25)16-6-2-1-3-7-16/h1-8,13H,9-12,14H2
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| InChIKey |
PGDHKPQSAXVTGR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform