General Information of the Compound
| Compound ID |
CP0852665
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| Compound Name |
N-[2-(4-Morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]benzenesulfonamide
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| Structure |
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| Formula |
C18H18N4O4S
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| Molecular Weight |
386.433
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| Canonical SMILES |
O=c1cc(N2CCOCC2)nc2c(NS(=O)(=O)c3ccccc3)cccn12
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| InChI |
InChI=1S/C18H18N4O4S/c23-17-13-16(21-9-11-26-12-10-21)19-18-15(7-4-8-22(17)18)20-27(24,25)14-5-2-1-3-6-14/h1-8,13,20H,9-12H2
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| InChIKey |
ISRRDHSXODUJMF-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform