General Information of the Compound
| Compound ID |
CP0347349
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| Compound Name |
4-morpholin-4-yl-2-[2-oxo-2-(4-pyridin-2-yl-2,3-dihydroindol-1-yl)ethyl]-1H-pyrimidin-6-one
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| Structure |
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| Formula |
C23H23N5O3
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| Molecular Weight |
417.469
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| Canonical SMILES |
O=C(Cc1nc(cc(=O)[nH]1)N1CCOCC1)N1CCc2c1cccc2-c1ccccn1
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| InChI |
InChI=1S/C23H23N5O3/c29-22-15-21(27-10-12-31-13-11-27)25-20(26-22)14-23(30)28-9-7-17-16(4-3-6-19(17)28)18-5-1-2-8-24-18/h1-6,8,15H,7,9-14H2,(H,25,26,29)
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| InChIKey |
QYWBMAVBPPCNAD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein ID: PT01029, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase