General Information of the Compound
| Compound ID |
CP0891905
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| Compound Name |
N-(4-Methylphenyl)-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
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| Structure |
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| Formula |
C20H20N4O3
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| Molecular Weight |
364.405
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| Canonical SMILES |
Cc1ccc(NC(=O)c2cccn3c(=O)cc(N4CCOCC4)nc23)cc1
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| InChI |
InChI=1S/C20H20N4O3/c1-14-4-6-15(7-5-14)21-20(26)16-3-2-8-24-18(25)13-17(22-19(16)24)23-9-11-27-12-10-23/h2-8,13H,9-12H2,1H3,(H,21,26)
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| InChIKey |
KVTLCPXSSRRLQI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform