General Information of the Compound
| Compound ID |
CP0002420
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| Compound Name |
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
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| Synonyms |
154447-36-6
15447-36-6
2-(4-Morpholino)-8-phenyl-4H-1-benzopyran-4-one
2-(4-Morpholinyl)-8-Phenyl-4h-1-Benzopyran-4-One
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
2-(morpholin-4-yl)-8-phenylchromen-4-one
2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE
2-morpholin-4-yl-8-phenyl-4H-chromen-4-one
2-morpholin-4-yl-8-phenylchromen-4-one
2-morpholino-8-phenyl-4H-chromen-4-one
2-morpholino-8-phenyl-chromen-4-one
31M2U1DVID
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-(9CI)
8-Phenyl-2-(morpholin-4-yl)-chromen-4-one
AK162301
BMK1-D5
CHEBI:65329
CHEMBL98350
H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-(9CI)
IN1266
IN1268
LY 294002
LY-294,002
LY-294002
LY2
LY294002
Lys 294002
UNII-31M2U1DVID
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| Structure |
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| Formula |
C19H17NO3
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| Molecular Weight |
307.349
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| Canonical SMILES |
O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
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| InChI |
InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
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| InChIKey |
CZQHHVNHHHRRDU-UHFFFAOYSA-N
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| CAS |
154447-36-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01002, Cytochrome P450 1A2
Protein ID: PT00955, DNA-dependent protein kinase catalytic subunit
Protein ID: PT00962, Glycogen synthase kinase-3 beta
Protein ID: PT03525, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01368, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein ID: PT01029, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein ID: PT02170, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000045 | A-375 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 8400 nM
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Clinical Information about the Compound