Brief Information of the Compound and Protein
Compound Name
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
    Show/Hide
PubChem ID
CID: 3973
SID: 14800773
Canonical SMILES
O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
    Show/Hide
Compound Formula C19H17NO3
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CL001056 MEF-1 [Mouse fibroblast] Mus musculus (Mouse)  1
1
Potency = 4645.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1060 nM
2 IC50 = 2500 nM
3 IC50 = 2800 nM
4 IC50 = 3018 nM
5 IC50 = 3900 nM
6 IC50 = 5000 nM
7 IC50 = 6796 nM
8 IC50 = 9900 nM
9 IC50 > 10000 nM