Brief Information of the Compound and Protein
Compound Name
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
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PubChem ID
CID: 3973
SID: 14800773
Canonical SMILES
O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
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Compound Formula C19H17NO3
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 6000 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 200 nM
2 IC50 = 300 nM
3 IC50 = 356 nM
4 IC50 = 480 nM
5 IC50 = 481 nM
6 IC50 = 500 nM
7 IC50 = 550 nM
8 IC50 = 600 nM
9 IC50 = 630 nM
10 IC50 = 720 nM
11 IC50 = 730 nM
12 IC50 = 2300 nM
13 IC50 = 4000 nM
14 IC50 = 6180 nM
15 IC50 = 62800 nM