General Information of the Compound
| Compound ID |
CP0889367
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| Compound Name |
2-(4-Morpholinyl)-4-oxo-N-(3-pyridinylmethyl)-4H-pyrido[1,2-a]pyrimidine-9-carboxamide
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| Structure |
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| Formula |
C19H19N5O3
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| Molecular Weight |
365.393
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| Canonical SMILES |
O=C(NCc1cccnc1)c1cccn2c(=O)cc(N3CCOCC3)nc12
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| InChI |
InChI=1S/C19H19N5O3/c25-17-11-16(23-7-9-27-10-8-23)22-18-15(4-2-6-24(17)18)19(26)21-13-14-3-1-5-20-12-14/h1-6,11-12H,7-10,13H2,(H,21,26)
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| InChIKey |
NIFDYLMXHVDYSD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform