General Information of the Compound
| Compound ID |
CP0461818
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| Compound Name |
N-[2-chloro-5-(4-piperidin-1-ylquinolin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
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| Structure |
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| Formula |
C25H22ClFN4O2S
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| Molecular Weight |
496.995
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| Canonical SMILES |
Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nccc(N3CCCCC3)c2c1
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| InChI |
InChI=1S/C25H22ClFN4O2S/c26-25-23(30-34(32,33)20-7-5-19(27)6-8-20)15-18(16-29-25)17-4-9-22-21(14-17)24(10-11-28-22)31-12-2-1-3-13-31/h4-11,14-16,30H,1-3,12-13H2
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| InChIKey |
ZCCGGRQYWABCQX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform