General Information of the Compound
| Compound ID |
CP0356739
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| Compound Name |
4-[2-(1H-indol-4-yloxy)pyridin-3-yl]-6-methylpyrimidin-2-amine
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| Structure |
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| Formula |
C18H15N5O
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| Molecular Weight |
317.352
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| Canonical SMILES |
Cc1cc(nc(N)n1)-c1cccnc1Oc1cccc2[nH]ccc12
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| InChI |
InChI=1S/C18H15N5O/c1-11-10-15(23-18(19)22-11)13-4-3-8-21-17(13)24-16-6-2-5-14-12(16)7-9-20-14/h2-10,20H,1H3,(H2,19,22,23)
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| InChIKey |
MMIJETCSDONNGS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein ID: PT01029, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform