General Information of the Compound
| Compound ID |
CP0346280
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| Compound Name |
N-[3-(6-amino-5-fluoro-2-methylpyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine
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| Structure |
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| Formula |
C17H14FN7
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| Molecular Weight |
335.346
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| Canonical SMILES |
Cc1nc(N)c(F)c(n1)-c1cccnc1Nc1cccc2[nH]ncc12
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| InChI |
InChI=1S/C17H14FN7/c1-9-22-15(14(18)16(19)23-9)10-4-3-7-20-17(10)24-12-5-2-6-13-11(12)8-21-25-13/h2-8H,1H3,(H,20,24)(H,21,25)(H2,19,22,23)
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| InChIKey |
HARJKCVVWJVELN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein ID: PT01029, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform