General Information of the Compound
| Compound ID |
CP0852658
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| Compound Name |
9-[(4-Methoxyphenoxy)methyl]-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one
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| Structure |
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| Formula |
C20H21N3O4
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| Molecular Weight |
367.405
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| Canonical SMILES |
COc1ccc(OCc2cccn3c(=O)cc(N4CCOCC4)nc23)cc1
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| InChI |
InChI=1S/C20H21N3O4/c1-25-16-4-6-17(7-5-16)27-14-15-3-2-8-23-19(24)13-18(21-20(15)23)22-9-11-26-12-10-22/h2-8,13H,9-12,14H2,1H3
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| InChIKey |
QJNINNARQWUXAI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01033, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein ID: PT00999, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform