| Compound ID |
Compound Name |
Compound Formula |
|
CP0495920
|
ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2,6-difluorophenyl)methyl]-2-[4-(methylcarbamoylamino)phenyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
|
C34H32F2N4O4S
|
1
|
| 1 |
IC50 = 0.06 nM
|
|
|
|
CP0039875
|
1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)methyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-methoxyurea
Show/Hide
|
C36H31F2N5O4S
|
7
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
| 3 |
IC50 = 0.6 nM
|
|
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| 4 |
IC50 = 1.6 nM
|
|
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| 5 |
IC50 = 1.9 nM
|
|
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| 6 |
IC50 = 10 nM
|
|
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| 7 |
IC50 = 270 nM
|
|
|
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CP0359982
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-2-[4-(3-methyluriedo)phenyl]-4-oxothieno[2,3-b]pyridine
Show/Hide
|
C35H34F2N4O3S
|
3
|
| 1 |
IC50 = 0.07 nM
|
|
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| 2 |
IC50 = 0.1 nM
|
|
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| 3 |
IC50 = 0.2 nM
|
|
|
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CP0464346
|
ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2-fluorophenyl)methyl]-2-[4-(methylcarbamoylamino)phenyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
|
C34H33FN4O4S
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
|
CP0061893
|
1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)methyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-ethylurea
Show/Hide
|
C37H33F2N5O3S
|
4
|
| 1 |
IC50 = 0.07 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
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| 3 |
IC50 = 0.3 nM
|
|
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| 4 |
IC50 = 7 nM
|
|
|
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CP0199103
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-3-(6-methoxypyridin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C32H32F2N6O6S
|
4
|
| 1 |
IC50 = 0.07 nM
|
|
|
| 2 |
IC50 = 0.2 nM
|
|
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| 3 |
IC50 = 0.49 nM
|
|
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| 4 |
IC50 = 0.8 nM
|
|
|
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CP0231917
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl(2-pyridin-2-ylethyl)amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C36H32F2N6O4S
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
|
CP0050490
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-3-(4-methoxyphenyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C33H33F2N5O6S
|
4
|
| 1 |
IC50 = 0.07 nM
|
|
|
| 2 |
IC50 = 0.17 nM
|
|
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| 3 |
IC50 = 0.29 nM
|
|
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| 4 |
IC50 = 0.43 nM
|
|
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CP0048798
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl(pyridin-2-ylmethyl)amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C35H30F2N6O4S
|
2
|
| 1 |
IC50 = 0.08 nM
|
|
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| 2 |
IC50 = 0.09 nM
|
|
|
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CP0050481
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C32H31F2N5O5S
|
4
|
| 1 |
IC50 = 0.08 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
| 3 |
IC50 = 0.5 nM
|
|
|
| 4 |
IC50 = 1.4 nM
|
|
|
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CP0295225
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C31H31F2N7O6S
|
4
|
| 1 |
IC50 = 0.08 nM
|
|
|
| 2 |
IC50 = 0.24 nM
|
|
|
| 3 |
IC50 = 0.26 nM
|
|
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| 4 |
IC50 = 0.94 nM
|
|
|
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CP0338284
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C29H27F2N7O5S
|
4
|
| 1 |
IC50 = 0.08 nM
|
|
|
| 2 |
IC50 = 0.33 nM
|
|
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| 3 |
IC50 = 0.82 nM
|
|
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| 4 |
IC50 = 18 nM
|
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CP0351993
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl-[2-(2-oxopyrrolidin-1-yl)ethyl]amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C35H34F2N6O5S
|
2
|
| 1 |
IC50 = 0.09 nM
|
|
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| 2 |
IC50 = 0.21 nM
|
|
|
|
CP0497061
|
7-Chloro-2-oxo-4-[2-(4-oxo-azetidin-2-yl)-ethoxy]-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
|
C26H24ClN5O4S
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 1.3 nM
|
|
|
|
CP0309511
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-[4-(1-hydroxy-1-cyclopropanecarboxamido)-phenyl]-5-isobutyryl-4-oxothieno[2,3-b]pyridine
Show/Hide
|
C37H37F2N3O4S
|
3
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
| 3 |
IC50 = 15 nM
|
|
|
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CP0464280
|
ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2,6-difluorophenyl)methyl]-4-oxo-2-[4-(propanoylamino)phenyl]thieno[2,3-b]pyridine-5-carboxylate
Show/Hide
|
C35H33F2N3O4S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0464345
|
N-[4-[5-benzoyl-3-[[benzyl(methyl)amino]methyl]-7-[(2,6-difluorophenyl)methyl]-4-oxothieno[2,3-b]pyridin-2-yl]phenyl]-2-methylpropanamide
Show/Hide
|
C40H35F2N3O3S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0509912
|
1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methylurea
Show/Hide
|
C36H31F2N5O3S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0048796
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[[6-(hydroxymethyl)pyridin-2-yl]methyl-methylamino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C36H32F2N6O5S
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 0.24 nM
|
|
|
|
CP0231905
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-3-(5-methylpyridin-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C32H32F2N6O5S
|
4
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 0.18 nM
|
|
|
| 3 |
IC50 = 0.3 nM
|
|
|
| 4 |
IC50 = 1.3 nM
|
|
|
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CP0050489
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C30H28F2N6O5S
|
4
|
| 1 |
IC50 = 0.12 nM
|
|
|
| 2 |
IC50 = 0.26 nM
|
|
|
| 3 |
IC50 = 0.55 nM
|
|
|
| 4 |
IC50 = 0.95 nM
|
|
|
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CP0039874
|
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester; hydrochloride
Show/Hide
|
C37H37F2N3O4S
|
4
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
| 3 |
IC50 = 2 nM
|
|
|
| 4 |
Ki = 0.2 nM
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CP0521653
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-(4-(2-hydroxy-2-methylpropionylamido)phenyl)-5-isobutyryl-4-oxothieno[2,3-b]pyridine
Show/Hide
|
C37H37F2N3O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
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CP0536569
|
N-[4-[3-[[benzyl(methyl)amino]methyl]-7-[(2,6-difluorophenyl)methyl]-5-(2-methylpropanoyl)-4-oxothieno[2,3-b]pyridin-2-yl]phenyl]-2-methylpropanamide
Show/Hide
|
C37H37F2N3O3S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0538121
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-[4-(2-hydroxyacetamido)phenyl]-5-isobutyryl-4-oxothieno[2,3-b]pyridine
Show/Hide
|
C35H33F2N3O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0897586
|
ethyl 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-(4-isobutyrylamidophenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate hydrochloride
Show/Hide
|
C36H36ClF2N3O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0405458
|
1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidin-6-yl]-phenyl}-3-isopropyl-urea; HCL.H2O
Show/Hide
|
C38H35F2N5O3S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
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CP0495465
|
N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]propanamide
Show/Hide
|
C38H34F2N4O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
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CP0508582
|
1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidin-6-yl]-phenyl}-3-ethoxy-urea; HCL.2.H2O
Show/Hide
|
C37H33F2N5O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
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CP0778924
|
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester hydrochloride
Show/Hide
|
C37H38ClF2N3O4S
|
3
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
| 3 |
IC50 = 2 nM
|
|
|
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CP0050491
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(5-fluoropyridin-2-yl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C31H29F3N6O5S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 1 nM
|
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|
|
CP0050492
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxo-3-pyridin-2-ylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C31H30F2N6O5S
|
4
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.3 nM
|
|
|
| 3 |
IC50 = 0.83 nM
|
|
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| 4 |
IC50 = 13 nM
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CP0143092
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl-[2-[methyl(methylsulfonyl)amino]ethyl]amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C33H34F2N6O6S2
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.27 nM
|
|
|
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CP0338285
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl(pyridin-3-ylmethyl)amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C35H30F2N6O4S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0342912
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-methoxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C29H33F2N5O6S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.29 nM
|
|
|
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CP0344569
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-ethoxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C30H35F2N5O6S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.37 nM
|
|
|
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CP0448182
|
3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-2-[4-(3-ethyl-ureido)-phenyl]-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid propyl ester
Show/Hide
|
C35H36F2N6O4
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0095035
|
7-Chloro-2-oxo-4-((S)-2-piperidin-2-yl-ethoxy)-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
Show/Hide
|
C30H32ClN5O3
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
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| 2 |
IC50 = 2.2 nM
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|
|
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CP0445881
|
7-Chloro-2-oxo-4-[2-(5-oxo-pyrrolidin-2-yl)-ethoxy]-3-((R)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
|
C27H26ClN5O4S
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
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| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0091820
|
ELIGARD
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|
C59H84N16O12
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0272654
|
N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]propanamide
Show/Hide
|
C37H32F2N4O3S
|
4
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 4 nM
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|
|
| 3 |
IC50 = 9 nM
|
|
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| 4 |
IC50 = 300 nM
|
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CP0481013
|
N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-2-methylpropanamide
Show/Hide
|
C39H36F2N4O4S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0050493
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-hydroxy-2-methylpropyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C30H35F2N5O6S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0292069
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl-[2-(triazol-1-yl)ethyl]amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C33H30F2N8O4S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0351991
|
1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-hydroxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
Show/Hide
|
C28H31F2N5O6S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0445780
|
4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
|
C26H26ClN5O3S
|
2
|
| 1 |
IC50 = 0.32 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
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CP0457343
|
3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-2-[4-(3-methoxy-ureido)-phenyl]-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid propyl ester
Show/Hide
|
C34H34F2N6O5
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0449419
|
ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxo-2-[4-(propanoylamino)phenyl]thieno[2,3-b]pyridine-5-carboxylate
Show/Hide
|
C35H35N3O4S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0495919
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-(1-hydroxy-2-methylpropyl)-2-(4-isobutyrylamidophenyl)-4-oxothieno[2,3-b]pyridine
Show/Hide
|
C37H39F2N3O3S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0511042
|
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-(4-isobutyrylamidophenyl)-4-oxo-5-propionyl-thieno[2,3-b]pyridine
Show/Hide
|
C36H35F2N3O3S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0193577
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N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-2-methylpropanamide
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C38H34F2N4O3S
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1
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| 1 |
IC50 = 0.4 nM
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CP0504133
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1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidin-6-yl]-phenyl}-3-hydroxy-urea; HCL.H2O
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C35H29F2N5O4S
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1
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| 1 |
IC50 = 0.4 nM
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CP0037858
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(S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(pyrimidin-4-yl)-3-(3,4,5-trimethylphenyl)-1,2-dihydroquinoline-6-carboxamide
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C28H28ClN5O3
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2
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| 1 |
IC50 = 0.44 nM
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| 2 |
IC50 = 0.9 nM
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CP0405359
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3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-2-[4-(3-ethyl-ureido)-phenyl]-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C34H34F2N6O4
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3
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| 1 |
IC50 = 0.5 nM
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| 2 |
IC50 = 70.79 nM
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| 3 |
Ki = 4.786 nM
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CP0433534
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7-Chloro-2-oxo-4-(2-piperidin-2-yl-ethoxy)-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
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C28H30ClN5O3S
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2
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| 1 |
IC50 = 0.55 nM
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| 2 |
IC50 = 1.6 nM
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CP0391243
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7-Chloro-2-oxo-4-[2-(tetrahydro-furan-2-yl)-ethoxy]-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
Show/Hide
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C29H29ClN4O4
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2
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| 1 |
IC50 = 0.6 nM
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| 2 |
IC50 = 3.3 nM
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CP0403266
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4-[2-(1-Aza-bicyclo[2.2.2]oct-2-yl)-ethoxy]-7-chloro-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
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C30H32ClN5O3S
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2
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| 1 |
IC50 = 0.6 nM
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| 2 |
IC50 = 5.8 nM
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CP0500775
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7-Chloro-4-(2-[1,3]dioxolan-2-yl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
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C26H25ClN4O5S
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2
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| 1 |
IC50 = 0.6 nM
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| 2 |
IC50 = 67 nM
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CP0461249
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-2-[4-(2-methylpropanoylamino)phenyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C36H37N3O4S
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1
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| 1 |
IC50 = 0.6 nM
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CP0497860
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1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidin-6-yl]-phenyl}-3-isopropoxy-urea; HCL.0.5 H2O
Show/Hide
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C38H35F2N5O4S
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1
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| 1 |
IC50 = 0.6 nM
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CP0397324
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3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-2-[4-(3-methoxy-ureido)-phenyl]-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C33H32F2N6O5
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1
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| 1 |
IC50 = 0.7 nM
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CP0439544
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7-Chloro-4-(2-morpholin-3-yl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
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C27H28ClN5O4S
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2
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| 1 |
IC50 = 0.7 nM
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| 2 |
IC50 = 32 nM
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CP0854506
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-([1,2,5]thiadiazol-3-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C29H29ClF3N5O5S
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2
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| 1 |
IC50 = 0.8 nM
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| 2 |
IC50 = 5.9 nM
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CP0455638
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7-Chloro-2-oxo-4-(2-pyrrolidin-2-yl-ethoxy)-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
Show/Hide
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C29H30ClN5O3
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2
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| 1 |
IC50 = 0.8 nM
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| 2 |
IC50 = 2.2 nM
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CP0874937
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyrimidin-4-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H31ClF3N5O5
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2
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| 1 |
IC50 = 0.9 nM
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| 2 |
IC50 = 5 nM
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CP0509637
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7-Chloro-4-(2-oxetan-2-yl-ethoxy)-2-oxo-3-((R)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
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C26H25ClN4O4S
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2
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| 1 |
IC50 = 0.9 nM
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| 2 |
IC50 = 49 nM
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CP0213550
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5-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1H-pyridin-2-one
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C37H46N4O2
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1
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| 1 |
IC50 = 1 nM
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CP0496785
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ethyl 2-(4-benzamidophenyl)-7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C39H35N3O4S
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1
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| 1 |
IC50 = 1 nM
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CP0061895
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N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]benzamide
Show/Hide
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C41H32F2N4O3S
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1
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| 1 |
IC50 = 1 nM
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CP0510377
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6-(4-Amino-phenyl)-5-[(benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3-(3-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.H2O
Show/Hide
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C35H30F2N4O3S
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1
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| 1 |
IC50 = 1 nM
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CP0853701
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Trifluoro-acetate2-{2-[7-chloro-6-(6-chloro-pyrimidin-4-ylcarbamoyl)-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H30Cl2F3N5O5
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2
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| 1 |
IC50 = 1.4 nM
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| 2 |
IC50 = 14.5 nM
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CP0227902
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5-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1-methyl-1H-pyridin-2-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
IC50 = 1.4 nM
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CP0432859
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7-Chloro-4-[2-(1-methyl-5-oxo-pyrrolidin-2-yl)-ethoxy]-2-oxo-3-((R)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
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C28H28ClN5O4S
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2
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| 1 |
IC50 = 1.4 nM
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| 2 |
IC50 = 11 nM
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CP0880181
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2-methyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H33ClF3N5O5
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2
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| 1 |
IC50 = 1.8 nM
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| 2 |
IC50 = 33.3 nM
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CP0299019
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1-(1R,4S)-2-Aza-bicyclo[2.2.1]hept-2-yl-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(2-pyridin-4-yl-ethylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C36H44N4O
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1
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| 1 |
IC50 = 1.9 nM
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CP0889555
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-([1,2,5]thiadiazol-3-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C29H29ClF3N5O5S
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 6.4 nM
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CP0392522
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7-Chloro-4-[2-((R)-1-methyl-6-trifluoromethyl-piperidin-2-yl)-ethoxy]-2-oxo-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
Show/Hide
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C32H33ClF3N5O3
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 18 nM
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CP0497965
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7-Chloro-2-oxo-4-[2-((R)-6-trifluoromethyl-piperidin-2-yl)-ethoxy]-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
Show/Hide
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C31H31ClF3N5O3
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 18 nM
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CP0486698
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ethyl 2-(4-acetamidophenyl)-7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C34H33N3O4S
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1
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| 1 |
IC50 = 2 nM
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CP0551303
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-2-[4-[methyl(methylcarbamoyl)amino]phenyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C35H36N4O4S
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1
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| 1 |
IC50 = 2 nM
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CP0869693
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(5-methyl-isoxazol-3-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H32ClF3N4O6
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2
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| 1 |
IC50 = 2.3 nM
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| 2 |
IC50 = 77.5 nM
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CP0135587
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(2-pyridin-3-yl-ethylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C37H46N4O
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1
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| 1 |
IC50 = 2.6 nM
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CP0880585
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(6-methyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H33ClF3N5O5
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2
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| 1 |
IC50 = 2.8 nM
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| 2 |
IC50 = 44 nM
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CP0216361
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 2.8 nM
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CP0866906
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(3-methyl-isothiazol-5-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H32ClF3N4O5S
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2
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| 1 |
IC50 = 2.9 nM
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| 2 |
IC50 = 21.5 nM
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CP0397655
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2-(4-Acryloylamino-phenyl)-3-[(benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C34H31F2N5O4
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1
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| 1 |
IC50 = 3 nM
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CP0458966
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3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-2-{4-[(furan-3-carbonyl)-amino]-phenyl}-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C36H31F2N5O5
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1
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| 1 |
IC50 = 3 nM
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CP0847468
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyrimidin-4-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H31ClF3N5O5
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2
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| 1 |
IC50 = 3.2 nM
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| 2 |
IC50 = 8.3 nM
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CP0847471
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyridin-2-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H32ClF3N4O5
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2
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| 1 |
IC50 = 3.6 nM
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| 2 |
IC50 = 19 nM
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CP0850053
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyridin-4-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H32ClF3N4O5
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2
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| 1 |
IC50 = 3.8 nM
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| 2 |
IC50 = 10.6 nM
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CP0522236
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5-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1-methoxymethyl-1H-pyridin-2-one
Show/Hide
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C39H50N4O3
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1
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| 1 |
IC50 = 3.9 nM
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CP0327922
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1-(1R,4S)-2-Aza-bicyclo[2.2.1]hept-2-yl-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 4 nM
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CP0371321
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5-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1,3-dimethyl-1H-pyridin-2-one
Show/Hide
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C39H50N4O2
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1
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| 1 |
IC50 = 4 nM
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CP0409867
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3-[(Benzyl-methyl-amino)-methyl]-2-[4-(cyclopropanecarbonyl-amino)-phenyl]-8-(2,6-difluoro-benzyl)-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C35H33F2N5O4
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1
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| 1 |
IC50 = 5 nM
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CP0063211
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 5.7 nM
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CP0361002
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(2-methyl-1-oxy-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
IC50 = 5.9 nM
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CP0112281
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3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-methoxy-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester
Show/Hide
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C33H30F2N2O4S
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1
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| 1 |
IC50 = 6 nM
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CP0364803
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]oct-6-yl)-propan-1-one
Show/Hide
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C42H56N4O
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1
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| 1 |
IC50 = 6.4 nM
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CP0122740
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(1-oxy-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C37H46N4O2
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1
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| 1 |
IC50 = 6.4 nM
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CP0336314
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1-(6-Aza-bicyclo[3.2.1]oct-6-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 6.8 nM
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CP0896758
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyrazin-2-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H31ClF3N5O5
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2
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| 1 |
IC50 = 7 nM
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| 2 |
IC50 = 16 nM
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CP0196863
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(2-pyridin-4-yl-ethylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C36H44N4O
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1
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| 1 |
IC50 = 7 nM
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CP0535305
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3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-5-oxo-2-{4-[(thiophene-3-carbonyl)-amino]-phenyl}-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C36H31F2N5O4S
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1
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| 1 |
IC50 = 7 nM
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CP0213240
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(S)-1-(2-aza-bicyclo[2.2.2]octan-2-yl)-2-(2-(3,5-dimethylphenyl)-3-(1-(2-(pyridin-4-yl)ethylamino)propan-2-yl)-1H-indol-5-yl)-2-methylpropan-1-one
Show/Hide
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C37H46N4O
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1
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| 1 |
IC50 = 7.2 nM
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CP0464146
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-2-[2-(2-hydroxymethyl-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
IC50 = 7.5 nM
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CP0464278
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3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-N-isopropyl-4-oxo-2-(4-propionylamidophenyl)-thieno[2,3-b]pyridine-5-carboxamide
Show/Hide
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C36H36F2N4O3S
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1
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| 1 |
IC50 = 8 nM
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CP0272840
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5-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1-methyl-piperidin-2-one
Show/Hide
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C38H52N4O2
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1
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| 1 |
IC50 = 8.2 nM
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CP0256294
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-N,N-diisobutyl-isobutyramide
Show/Hide
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C39H54N4O
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1
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| 1 |
IC50 = 8.3 nM
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CP0076599
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1-(1S,4R)-2-Aza-bicyclo[2.2.1]hept-2-yl-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
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C38H48N4O
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1
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| 1 |
IC50 = 8.7 nM
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CP0208585
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(2-methyl-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 8.7 nM
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CP0334675
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1-(8-Aza-bicyclo[3.2.1]oct-8-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 8.8 nM
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CP0845332
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2-methoxy-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H33ClF3N5O6
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2
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| 1 |
IC50 = 9 nM
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| 2 |
IC50 = 133 nM
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CP0524417
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2-[4-(2-aminoacetamido)phenyl]-3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-4-oxothieno[2,3-b]pyridine
Show/Hide
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C35H34F2N4O3S
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1
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| 1 |
IC50 = 9 nM
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CP0510586
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3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-5-oxo-2-(4-propionylamino-phenyl)-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C34H33F2N5O4
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1
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| 1 |
IC50 = 10 nM
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CP0257614
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-[3-{(S)-2-[2-(2,6-dimethyl-1-oxy-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-2-(3,5-dimethyl-phenyl)-1H-indol-5-yl]-2-methyl-propan-1-one
Show/Hide
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C39H50N4O2
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1
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| 1 |
IC50 = 10 nM
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CP0110348
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(S)-1-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-3-(1H-imidazol-5-yl)-2-((S)-2-oxopyrrolidine-5-carboxamido)propanamido)-3-(1H-indol-2-yl)propanamido)-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)acetamido)-4-methylpentanamido)-5-(diaminomethylene
Show/Hide
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C53H72N16O12
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1
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| 1 |
IC50 = 10 nM
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CP0921767
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Trifluoro-acetate2-{2-[7-chloro-6-(4-dimethylamino-phenylcarbamoyl)-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C35H38ClF3N4O5
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2
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| 1 |
IC50 = 10.9 nM
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| 2 |
IC50 = 360 nM
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CP0219557
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-2-[2-(6-methoxy-pyridin-3-yl)-ethylamino]-1-methyl-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
IC50 = 11 nM
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CP0221205
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4-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-pyridine-2-carbonitrile
Show/Hide
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C38H45N5O
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1
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| 1 |
IC50 = 11 nM
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CP0043368
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid diethylamide
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C32H40N4O
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1
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| 1 |
IC50 = 12 nM
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CP0463978
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2-[3-{(S)-2-[2-(2-Acetyl-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-2-(3,5-dimethyl-phenyl)-1H-indol-5-yl]-1-(2-aza-bicyclo[2.2.2]oct-2-yl)-2-methyl-propan-1-one
Show/Hide
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C39H48N4O2
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1
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| 1 |
IC50 = 12 nM
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CP0196182
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1-(3-Aza-bicyclo[3.2.2]non-3-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C40H52N4O
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1
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| 1 |
IC50 = 13 nM
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CP0219252
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-N,N-diisobutyl-isobutyramide
Show/Hide
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C40H56N4O
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1
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| 1 |
IC50 = 14 nM
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CP0291132
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C37H46N4O
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1
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| 1 |
IC50 = 14 nM
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CP0847905
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Trifluoro-acetate2-{2-[7-chloro-6-(2-cyclopropyl-pyrimidin-4-ylcarbamoyl)-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C34H35ClF3N5O5
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2
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| 1 |
IC50 = 15 nM
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| 2 |
IC50 = 250 nM
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CP0299802
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(2,5-dimethyl-pyrrolidin-1-yl)-2-methyl-propan-1-one
Show/Hide
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C37H48N4O
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1
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| 1 |
IC50 = 15 nM
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CP0332602
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid cyclooctyl-ethyl-amide
Show/Hide
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C38H50N4O
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1
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| 1 |
IC50 = 15 nM
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CP0309400
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid cyclohexyl-ethyl-amide
Show/Hide
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C36H46N4O
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1
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| 1 |
IC50 = 16 nM
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CP0236982
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C37H46N4O
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1
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| 1 |
IC50 = 18 nM
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CP0255311
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{2-[methyl-(4-pyridin-4-yl-butyl)-amino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 18 nM
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CP0055695
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-2-[2-(2-ethyl-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 19 nM
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CP0460098
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2-(4-Benzoylamino-phenyl)-3-[(benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-benzyl)-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C38H33F2N5O4
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1
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| 1 |
IC50 = 20 nM
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CP0215042
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-[2-(3,5-dimethyl-phenyl)-3-((S)-2-{2-[2-(1-hydroxy-ethyl)-pyridin-4-yl]-ethylamino}-1-methyl-ethyl)-1H-indol-5-yl]-2-methyl-propan-1-one
Show/Hide
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C39H50N4O2
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1
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| 1 |
IC50 = 20 nM
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CP0401406
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N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N-methylpropanamide
Show/Hide
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C39H36F2N4O4S
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1
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| 1 |
IC50 = 20 nM
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CP0508595
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3-(3-methoxy-phenyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.8H2O
Show/Hide
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C36H31F2N3O4S
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1
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| 1 |
IC50 = 20 nM
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CP0534533
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3-(3-methoxy-phenyl)-6-(4-nitro-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL8.H2O
Show/Hide
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C35H28F2N4O5S
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1
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| 1 |
IC50 = 20 nM
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CP0136681
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1-(3,3-Dimethyl-azetidin-1-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C37H48N4O
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1
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| 1 |
IC50 = 21 nM
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CP0868282
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-([1,3,4]thiadiazol-2-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C29H29ClF3N5O5S
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2
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| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 32 nM
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CP0190899
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-N,N-diisobutyl-isobutyramide
Show/Hide
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C39H54N4O
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1
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| 1 |
IC50 = 22 nM
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CP0288623
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid cyclohexyl-ethyl-amide
Show/Hide
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C36H46N4O
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1
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| 1 |
IC50 = 22 nM
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CP0299579
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Acetic acid 4-(2-{(S)-2-[5-[2-(2-aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-pyridin-2-ylmethyl ester
Show/Hide
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C40H50N4O3
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1
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| 1 |
IC50 = 22 nM
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CP0874971
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(3-methyl-isoxazol-5-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H32ClF3N4O6
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1
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| 1 |
IC50 = 23 nM
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CP0115024
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-2-[2-(2,6-dimethyl-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 24 nM
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CP0082419
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4-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-pyridine-2-carboxylic acid methyl ester
Show/Hide
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C39H48N4O3
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1
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| 1 |
IC50 = 25 nM
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CP0215181
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(3-methyl-1-oxy-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O2
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1
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| 1 |
IC50 = 26 nM
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CP0917751
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(5-methyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C30H31ClF3N5O5S
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1
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| 1 |
IC50 = 28 nM
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CP0535333
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3-[(Benzyl-methyl-amino)-methyl]-2-(4-butyrylamino-phenyl)-8-(2,6-difluoro-benzyl)-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester
Show/Hide
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C35H35F2N5O4
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1
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| 1 |
IC50 = 30 nM
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CP0464281
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxo-2-[4-(phenylcarbamoylamino)phenyl]thieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C39H36N4O4S
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1
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| 1 |
IC50 = 30 nM
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CP0501953
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ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2-fluorophenyl)methyl]-2-(4-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H31FN2O4S
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1
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| 1 |
IC50 = 30 nM
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CP0531940
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3,6-bis-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.0.5H2O
Show/Hide
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C36H31F2N3O4S
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1
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| 1 |
IC50 = 30 nM
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CP0149717
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(dodecahydro-carbazol-9-yl)-2-methyl-propan-1-one
Show/Hide
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C44H58N4O
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1
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| 1 |
IC50 = 31 nM
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CP0850063
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyridin-3-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C32H32ClF3N4O5
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2
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| 1 |
IC50 = 32 nM
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| 2 |
IC50 = 130 nM
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CP0150494
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-butan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 38 nM
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CP0331985
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-piperidin-1-yl-propan-1-one
Show/Hide
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C36H46N4O
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1
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| 1 |
IC50 = 38 nM
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CP0223103
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(4,4-dimethyl-piperidin-1-yl)-2-methyl-propan-1-one
Show/Hide
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C39H52N4O
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1
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| 1 |
IC50 = 39 nM
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CP0880605
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C33H35ClF3N5O5
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2
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| 1 |
IC50 = 40 nM
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| 2 |
IC50 = 486 nM
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CP0310600
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-ethyl-butan-1-one
Show/Hide
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C39H50N4O
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1
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| 1 |
IC50 = 40 nM
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CP0439642
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ethyl 2-(4-aminophenyl)-7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C32H31N3O3S
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1
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| 1 |
IC50 = 40 nM
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CP0853700
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Trifluoro-acetate2-{2-[7-chloro-6-(di-sec-butyl-carbamoyl)-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C35H45ClF3N3O5
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1
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| 1 |
IC50 = 45 nM
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CP0172193
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(3-methyl-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C38H48N4O
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1
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| 1 |
IC50 = 48 nM
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CP0384674
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-3-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.5H2O
Show/Hide
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C35H29F2N3O3S
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1
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| 1 |
IC50 = 50 nM
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CP0290421
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N-cyclohexyl-2-[2-(3,5-dimethylphenyl)-3-[2-(4-pyridin-4-ylbutylamino)ethyl]-1H-indol-5-yl]-N-ethyl-2-methylpropanamide
Show/Hide
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C39H52N4O
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1
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| 1 |
IC50 = 54 nM
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CP0155115
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-2-[2-(2-methoxymethyl-pyridin-4-yl)-ethylamino]-1-methyl-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C39H50N4O2
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1
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| 1 |
IC50 = 55 nM
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CP0214051
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-N,N-diethyl-isobutyramide
Show/Hide
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C35H46N4O
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1
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| 1 |
IC50 = 58 nM
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CP0352069
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2-(3,5-Dimethyl-phenyl)-3-{2-[methyl-(4-pyridin-4-yl-butyl)-amino]-ethyl}-1H-indole-5-carboxylic acid diethylamide
Show/Hide
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C33H42N4O
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1
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| 1 |
IC50 = 58 nM
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CP0138177
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-morpholin-4-yl-propan-1-one
Show/Hide
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C35H44N4O2
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1
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| 1 |
IC50 = 59 nM
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CP0369348
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-pyrrolidin-1-yl-propan-1-one
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C35H44N4O
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1
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| 1 |
IC50 = 61 nM
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CP0207774
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1-(3,3-Dimethyl-azetidin-1-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
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C36H46N4O
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1
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| 1 |
IC50 = 62 nM
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CP0286926
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[2-(3,5-dimethylphenyl)-3-[2-(4-pyridin-3-ylbutylamino)ethyl]-1H-indol-5-yl]-(2,5-dimethylpyrrolidin-1-yl)methanone
Show/Hide
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C34H42N4O
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1
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| 1 |
IC50 = 62 nM
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CP0193348
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{(S)-1-methyl-2-[2-(2-propyl-pyridin-4-yl)-ethylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
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C40H52N4O
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1
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| 1 |
IC50 = 62 nM
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CP0225806
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-(3aR,7aS)-octahydro-isoindol-2-yl-propan-1-one
Show/Hide
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C40H52N4O
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1
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| 1 |
IC50 = 66 nM
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CP0246348
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-2-methyl-propan-1-one
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C39H50N4O3
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1
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| 1 |
IC50 = 66 nM
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CP0182886
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3-[(Benzyl-methyl-amino)-methyl]-7-(2-methoxy-benzyl)-2-(4-methoxy-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester
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C34H34N2O5S
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1
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| 1 |
IC50 = 70 nM
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CP0054992
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid diisobutylamide
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C36H48N4O
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1
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| 1 |
IC50 = 80 nM
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CP0453601
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5-[(Benzyl-methyl-amino)-methyl]-3-(2-chloro-phenyl)-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.5H2O
Show/Hide
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C35H28ClF2N3O3S
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1
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| 1 |
IC50 = 80 nM
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CP0299531
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3-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-1-methyl-1H-pyridin-2-one
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C38H48N4O2
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1
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| 1 |
IC50 = 82 nM
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CP0252860
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{2-[ethyl-(4-pyridin-4-yl-butyl)-amino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
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C39H50N4O
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1
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| 1 |
IC50 = 90 nM
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CP0297942
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid bis-(2,2,2-trifluoro-ethyl)-amide
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C32H34F6N4O
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1
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| 1 |
IC50 = 91 nM
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CP0524086
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1-(8-Aza-spiro[4.5]dec-8-yl)-2-{2-(3,5-dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propan-1-one
Show/Hide
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C41H54N4O
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1
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| 1 |
IC50 = 93 nM
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CP0184382
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-N,N-diethyl-isobutyramide
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C35H46N4O
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1
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| 1 |
IC50 = 94 nM
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CP0386028
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ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2-cyanophenyl)methyl]-2-(4-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C34H31N3O4S
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1
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| 1 |
IC50 = 100 nM
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CP0551304
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-7-[(2-nitrophenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C33H31N3O6S
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1
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| 1 |
IC50 = 100 nM
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CP0194543
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1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-[2-(3,5-dimethyl-phenyl)-3-((S)-2-{2-[2-(1-hydroxy-1-methyl-ethyl)-pyridin-4-yl]-ethylamino}-1-methyl-ethyl)-1H-indol-5-yl]-2-methyl-propan-1-one
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C40H52N4O2
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1
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| 1 |
IC50 = 106 nM
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CP0849296
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Trifluoro-acetate2-{2-[6-[(benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C35H35ClF3N3O7
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2
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| 1 |
IC50 = 110 nM
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| 2 |
IC50 = 591 nM
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CP0368048
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid ethyl-isopropyl-amide
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C33H42N4O
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1
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| 1 |
IC50 = 110 nM
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CP0045709
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid diisobutylamide
Show/Hide
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C36H48N4O
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1
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| 1 |
IC50 = 120 nM
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CP0223421
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2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-1-(4-ethanesulfonyl-piperazin-1-yl)-2-methyl-propan-1-one
Show/Hide
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C38H51N5O3S
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1
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| 1 |
IC50 = 124 nM
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CP0163117
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(7-Aza-bicyclo[2.2.1]hept-7-yl)-(1-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-cyclobutyl)-methanone
Show/Hide
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C38H46N4O
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1
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| 1 |
IC50 = 170 nM
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CP0916409
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Trifluoro-acetate2-{2-[7-chloro-6-diethylcarbamoyl-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H37ClF3N3O5
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1
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| 1 |
IC50 = 190 nM
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CP0105024
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid diethylamide
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C32H40N4O
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1
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| 1 |
IC50 = 190 nM
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CP0244439
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{2-[isopropyl-(4-pyridin-4-yl-butyl)-amino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C40H52N4O
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1
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| 1 |
IC50 = 200 nM
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CP0436282
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ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(2-methoxyphenyl)methyl]-4-oxo-2-phenylthieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H32N2O4S
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1
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| 1 |
IC50 = 200 nM
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CP0500544
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H32N2O4S
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1
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| 1 |
IC50 = 200 nM
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CP0384670
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5-[(Benzyl-methyl-amino)-methyl]-3-(3-chloro-phenyl)-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.H2O
Show/Hide
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C35H28ClF2N3O3S
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1
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| 1 |
IC50 = 200 nM
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CP0405427
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3-(2-methoxy-phenyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.1.5H2O
Show/Hide
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C36H31F2N3O4S
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1
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| 1 |
IC50 = 200 nM
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CP0531947
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5-[(Benzyl-methyl-amino)-methyl]-3-(4-chloro-phenyl)-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.H2O
Show/Hide
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C35H28ClF2N3O3S
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1
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| 1 |
IC50 = 200 nM
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CP0196914
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4-(2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-propionyl)-piperazine-1-carboxylic acid tert-butyl ester
Show/Hide
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C41H55N5O3
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1
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| 1 |
IC50 = 220 nM
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CP0445880
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7-Chloro-4-(2-cyclopentyl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Show/Hide
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C28H29ClN4O3S
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2
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| 1 |
IC50 = 243 nM
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| 2 |
IC50 = 1150 nM
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CP0041665
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid ethyl-(2-hydroxy-ethyl)-amide
Show/Hide
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C32H40N4O2
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1
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| 1 |
IC50 = 260 nM
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CP0214050
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(7-Aza-bicyclo[2.2.1]hept-7-yl)-{2-(3,5-dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-methanone
Show/Hide
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C34H40N4O
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1
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| 1 |
IC50 = 260 nM
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CP0847491
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyrimidin-2-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C31H31ClF3N5O5
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2
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| 1 |
IC50 = 290 nM
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| 2 |
IC50 > 3200 nM
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CP0300561
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1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-(2-(3,5-dimethyl-phenyl)-3-{2-[isobutyl-(4-pyridin-4-yl-butyl)-amino]-ethyl}-1H-indol-5-yl)-2-methyl-propan-1-one
Show/Hide
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C41H54N4O
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1
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| 1 |
IC50 = 300 nM
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CP0449533
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-7-[(4-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C34H34N2O5S
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1
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| 1 |
IC50 = 300 nM
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CP0485573
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ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(3-fluorophenyl)methyl]-2-(4-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H31FN2O4S
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1
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| 1 |
IC50 = 300 nM
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CP0551305
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ethyl 3-[[benzyl(ethyl)amino]methyl]-2-(4-methoxyphenyl)-7-[(2-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C35H36N2O5S
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1
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| 1 |
IC50 = 300 nM
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CP0373317
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ethyl 3-[[benzyl-[2-[[1-[2-[2-[2-[2-[2-[4-[[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C86H94F4N20O14
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2
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| 1 |
IC50 = 309.03 nM
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| 2 |
Ki = 194.98 nM
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CP0847053
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(4H-[1,2,4]triazol-3-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
Show/Hide
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C29H30ClF3N6O5
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2
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| 1 |
IC50 = 320 nM
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| 2 |
IC50 = 775 nM
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CP0376521
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2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-isobutyramide
Show/Hide
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C31H38N4O
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1
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| 1 |
IC50 = 350 nM
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CP0535910
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-[4-[[1-[2-[2-[2-[2-[4-[[[4-[3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-5-oxoimidazo[1,2-a]pyrimidin-2-yl]phenyl]carbamoylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C78H80F4N18O11
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2
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| 1 |
IC50 = 354.81 nM
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| 2 |
Ki = 29.51 nM
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CP0363826
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4-(2-{(S)-2-[5-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-pyridine-2-carboxylic acid
Show/Hide
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C38H46N4O3
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1
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| 1 |
IC50 = 371 nM
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CP0464282
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ethyl 3-[[benzyl(methyl)amino]methyl]-7-[(4-fluorophenyl)methyl]-2-(4-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H31FN2O4S
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1
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| 1 |
IC50 = 400 nM
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CP0529753
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-7-[(3-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C34H34N2O5S
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1
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| 1 |
IC50 = 400 nM
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CP0461051
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3-Benzyl-5-[(benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.5H2O
Show/Hide
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C36H31F2N3O3S
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1
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| 1 |
IC50 = 400 nM
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CP0522471
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5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-3-isobutyl-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL
Show/Hide
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C33H33F2N3O3S
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1
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| 1 |
IC50 = 400 nM
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CP0373316
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ethyl 3-[[[2-[[1-[2-[2-(2-azidoethoxy)ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]-benzylamino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C44H49F2N13O7
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1
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| 1 |
IC50 = 467.74 nM
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CP0464285
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ethyl 3-[(dimethylamino)methyl]-2-(4-methoxyphenyl)-7-[(2-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C28H30N2O5S
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1
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| 1 |
IC50 = 500 nM
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CP0486699
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-2-(3-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H32N2O4S
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1
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| 1 |
IC50 = 500 nM
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CP0374809
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ethyl 3-[[[2-[[1-[2-(2-azidoethoxy)ethyl]triazol-4-yl]methylamino]-2-oxoethyl]-benzylamino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C42H45F2N13O6
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1
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| 1 |
IC50 = 524.81 nM
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CP0258027
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid bis-(2-methoxy-ethyl)-amide
Show/Hide
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C34H44N4O3
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1
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| 1 |
IC50 = 610 nM
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CP0435797
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ethyl 3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxo-2-[4-(prop-2-ynylcarbamoylamino)phenyl]imidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C35H32F2N6O4
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2
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| 1 |
IC50 = 676.08 nM
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| 2 |
Ki = 1.349 nM
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CP0436605
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ethyl 2-[4-[[1-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C45H52F2N12O8
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1
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| 1 |
IC50 = 676.08 nM
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CP0538123
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ethyl 7-benzyl-3-[[benzyl(methyl)amino]methyl]-2-(2-methoxyphenyl)-4-oxothieno[2,3-b]pyridine-5-carboxylate
Show/Hide
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C33H32N2O4S
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1
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| 1 |
IC50 = 700 nM
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CP0439698
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5-[(Benzyl-methyl-amino)-methyl]-3-cyclohexyl-1-(2,6-difluoro-benzyl)-6-(4-methoxy-phenyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione; HCL.0.5H2O
Show/Hide
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C35H35F2N3O3S
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1
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| 1 |
IC50 = 700 nM
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CP0373318
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ethyl 3-[[[2-[[1-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]-benzylamino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C46H53F2N13O8
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1
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| 1 |
IC50 = 724.44 nM
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CP0445447
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ethyl 3-[[[2-[[1-(2-azidoethyl)triazol-4-yl]methylamino]-2-oxoethyl]-benzylamino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
Show/Hide
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C40H41F2N13O5
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1
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| 1 |
IC50 = 724.44 nM
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CP0373315
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ethyl 3-[[benzyl-[2-[[1-[2-[2-[2-[4-[[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C82H86F4N20O12
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2
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| 1 |
IC50 = 831.76 nM
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| 2 |
Ki = 58.88 nM
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CP0509408
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ethyl 3-[[[2-[[1-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]-benzylamino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C48H57F2N13O9
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1
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| 1 |
IC50 = 831.76 nM
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CP0874996
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Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2-ethyl-2H-pyrazol-3-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium
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C32H35ClF3N5O5
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2
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| 1 |
IC50 = 860 nM
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| 2 |
IC50 = 977 nM
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CP0530448
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-[4-[[1-[2-[2-[2-[4-[[[4-[3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-5-oxoimidazo[1,2-a]pyrimidin-2-yl]phenyl]carbamoylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C76H76F4N18O10
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2
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| 1 |
IC50 = 954.99 nM
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| 2 |
Ki = 23.44 nM
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CP0541694
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ethyl 3-[[benzyl-[2-oxo-2-(prop-2-ynylamino)ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C38H37F2N7O5
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2
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| 1 |
IC50 = 1000 nM
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| 2 |
Ki = 5.248 nM
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CP0256086
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2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid isopropylamide
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C31H38N4O
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1
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| 1 |
IC50 = 1200 nM
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CP0405362
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ethyl 3-[[benzyl-[2-[[1-[2-[2-[2-[2-[4-[[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C84H90F4N20O13
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2
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| 1 |
IC50 = 1318.26 nM
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| 2 |
Ki = 69.18 nM
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CP0435279
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-[4-[[1-[2-[2-[2-[2-[2-[4-[[[4-[3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-5-oxoimidazo[1,2-a]pyrimidin-2-yl]phenyl]carbamoylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C80H84F4N18O12
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1
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| 1 |
IC50 = 1348.96 nM
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CP0442969
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ethyl 3-[[benzyl-[2-[[1-[2-[2-[4-[[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]methyl]triazol-1-yl]ethoxy]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C80H82F4N20O11
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1
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| 1 |
IC50 = 1548.82 nM
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CP0435798
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ethyl 3-[[benzyl-[2-[[1-[2-[4-[[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]methyl]triazol-1-yl]ethyl]triazol-4-yl]methylamino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C78H78F4N20O10
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1
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| 1 |
IC50 = 1905.46 nM
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CP0500896
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-[4-[[1-[2-[4-[[[4-[3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-5-oxoimidazo[1,2-a]pyrimidin-2-yl]phenyl]carbamoylamino]methyl]triazol-1-yl]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C72H68F4N18O8
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1
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| 1 |
IC50 = 1905.46 nM
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CP0076365
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7-(2-Methoxy-benzyl)-2-(4-methoxy-phenyl)-3-methylaminomethyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester
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C27H28N2O5S
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1
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| 1 |
IC50 = 2000 nM
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CP0523763
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ethyl 3-[(benzylamino)methyl]-2-(4-methoxyphenyl)-7-[(2-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C33H32N2O5S
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1
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| 1 |
IC50 = 2000 nM
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CP0504053
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ethyl 2-[4-[[1-[2-[2-(2-azidoethoxy)ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C41H44F2N12O6
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1
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| 1 |
IC50 = 2398.83 nM
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CP0464694
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ethyl 2-[4-[[1-(2-azidoethyl)triazol-4-yl]methylcarbamoylamino]phenyl]-3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C37H36F2N12O4
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1
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| 1 |
IC50 = 2570.4 nM
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CP0480378
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ethyl 2-[4-[[1-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C43H48F2N12O7
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1
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| 1 |
IC50 = 3019.95 nM
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CP0437227
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-[4-[[1-[2-[2-[4-[[[4-[3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-5-oxoimidazo[1,2-a]pyrimidin-2-yl]phenyl]carbamoylamino]methyl]triazol-1-yl]ethoxy]ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C74H72F4N18O9
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1
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| 1 |
IC50 = 3162.28 nM
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CP0437872
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ethyl 2-[4-[[1-[2-(2-azidoethoxy)ethyl]triazol-4-yl]methylcarbamoylamino]phenyl]-3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C39H40F2N12O5
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1
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| 1 |
IC50 = 3630.78 nM
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CP0501954
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-7-methyl-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C27H28N2O4S
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1
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| 1 |
IC50 = 5000 nM
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CP0542982
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ethyl 3-[[acetyl(benzyl)amino]methyl]-2-(4-methoxyphenyl)-7-[(2-methoxyphenyl)methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C35H34N2O6S
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1
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| 1 |
IC50 = 7000 nM
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CP0435772
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3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxo-N-prop-2-ynylimidazo[1,2-a]pyrimidine-6-carboxamide
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C35H33F2N7O3
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2
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| 1 |
IC50 = 7079.46 nM
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| 2 |
Ki = 162.18 nM
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CP0515771
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ethyl 2-(4-methoxyphenyl)-7-[(2-methoxyphenyl)methyl]-3-methyl-4-oxothieno[2,3-b]pyridine-5-carboxylate
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C26H25NO5S
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1
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| 1 |
IC50 = 10000 nM
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CP0501955
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ethyl 3-[[benzyl(methyl)amino]methyl]-2-(4-methoxyphenyl)-4-oxo-7H-thieno[2,3-b]pyridine-5-carboxylate
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C26H26N2O4S
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1
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| 1 |
IC50 > 20000 nM
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CP0871618
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3-{[benzyl(methyl)amino]methyl}-N-{[1-(2-{2-[2-(4-{[(3-{[benzyl(methyl)amino]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidin-6-yl)formamido]methyl}-1H-1,2,3-triazol-1-yl)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(methylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidine-6-carboxamide
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C75H76F4N20O8
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1
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| 1 |
IC50 < 10000 nM
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CP0877635
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3-{[benzyl(methyl)amino]methyl}-N-({1-[2-(2-{2-[2-(4-{[(3-{[benzyl(methyl)amino]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidin-6-yl)formamido]methyl}-1H-1,2,3-triazol-1-yl)ethoxy]ethoxy}ethoxy)ethyl]-1H-1,2,3-triazol-4-yl}methyl)-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidine-6-carboxamide
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C78H82F4N20O9
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1
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| 1 |
IC50 < 10000 nM
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CP0877638
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1-(4-(8-(2,6-difluorobenzyl)-6-(((1-(2-(2-azidoethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)-3-((benzyl(methyl)amino)methyl)-5-oxo-5,8-dihydroimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-ethylurea
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C39H41F2N13O4
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1
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| 1 |
IC50 < 10000 nM
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CP0878009
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1-(4-(8-(2,6-difluorobenzyl)-6-(((1-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)-3-((benzyl(methyl)amino)methyl)-5-oxo-5,8-dihydroimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-ethylurea
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C43H49F2N13O6
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1
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| 1 |
IC50 < 10000 nM
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CP0878010
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3-{[benzyl(methyl)amino]methyl}-N-({1-[2-(4-{[(3-{[benzyl(methyl)amino]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidin-6-yl)formamido]methyl}-1H-1,2,3-triazol-1-yl)ethyl]-1H-1,2,3-triazol-4-yl}methyl)-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidine-6-carboxamide
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C72H70F4N20O6
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1
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| 1 |
IC50 < 10000 nM
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CP0878011
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1-(4-(8-(2,6-difluorobenzyl)-6-(((1-(2-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)-3-((benzyl(methyl)amino)methyl)-5-oxo-5,8-dihydroimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-ethylurea
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C45H53F2N13O7
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1
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| 1 |
IC50 < 10000 nM
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CP0883044
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1-(4-(8-(2,6-difluorobenzyl)-6-(((1-(2-azidoethyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)-3-((benzyl(methyl)amino)methyl)-5-oxo-5,8-dihydroimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-ethylurea
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C37H37F2N13O3
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1
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| 1 |
IC50 < 10000 nM
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CP0886316
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3-{[benzyl(methyl)amino]methyl}-N-[(1-{2-[2-(4-{[(3-{[benzyl(methyl)amino]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidin-6-yl)formamido]methyl}-1H-1,2,3-triazol-1-yl)ethoxy]ethyl}-1H-1,2,3-triazol-4-yl)methyl]-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidine-6-carboxamide
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C74H74F4N20O7
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1
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| 1 |
IC50 < 10000 nM
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CP0886560
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3-{[benzyl(methyl)amino]methyl}-N-({1-[14-(4-{[(3-{[benzyl(methyl)amino]methyl}-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidin-6-yl)formamido]methyl}-1H-1,2,3-triazol-1-yl)-3,6,9,12-tetraoxatetradecan-1-yl]-1H-1,2,3-triazol-4-yl}methyl)-8-[(2,6-difluorophenyl)methyl]-2-{4-[(ethylcarbamoyl)amino]phenyl}-5-oxo-5H,8H-imidazo[1,2-a]pyrimidine-6-carboxamide
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C80H86F4N20O10
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1
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| 1 |
IC50 < 10000 nM
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CP0941391
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1-(4-(8-(2,6-difluorobenzyl)-6-(((1-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)-3-((benzyl(methyl)amino)methyl)-5-oxo-5,8-dihydroimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-ethylurea
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C41H45F2N13O5
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1
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| 1 |
IC50 < 10000 nM
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CP0403789
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(3-chloro-4-fluorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclopropylmethyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H69ClFN3O13
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1
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| 1 |
Ki = 0.3311 nM
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CP0480685
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[bis(cyclopropylmethyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(3-chloro-4-fluorophenyl)ethyl]-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C53H82ClFN2O13
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1
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| 1 |
Ki = 0.8511 nM
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CP0533022
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[bis(cyclopropylmethyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(3,4-dichlorophenyl)ethyl]-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C50H73Cl2N3O13
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1
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| 1 |
Ki = 1.288 nM
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CP0522002
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[cyclopentyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(3,4-dichlorophenyl)ethyl]-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C51H80Cl2N2O13
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1
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| 1 |
Ki = 1.514 nM
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CP0211775
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A-198401
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C47H69Cl2N3O13
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1
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| 1 |
Ki = 1.862 nM
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CP0403723
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclopentyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C48H72ClN3O13
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2
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| 1 |
Ki = 3.89 nM
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| 2 |
Ki = 38.02 nM
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CP0453836
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[cyclopentyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(3,4-dichlorophenyl)ethyl]-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C48H71Cl2N3O13
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1
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| 1 |
Ki = 5.623 nM
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CP0375492
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[cyclohexyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(3,4-dichlorophenyl)ethyl]-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C49H73Cl2N3O13
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1
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| 1 |
Ki = 7.244 nM
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CP0514478
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclopentyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C51H81ClN2O13
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1
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| 1 |
Ki = 7.586 nM
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CP0520257
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclopropylmethyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C50H79ClN2O13
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1
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| 1 |
Ki = 13.18 nM
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CP0374667
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(3,4-dichlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C46H69Cl2N3O13
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1
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| 1 |
Ki = 15.14 nM
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CP0430480
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclopropylmethyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H70ClN3O13
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1
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| 1 |
Ki = 18.62 nM
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CP0448714
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C46H70ClN3O13
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1
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| 1 |
Ki = 18.62 nM
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CP0394212
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C49H79ClN2O13
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1
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| 1 |
Ki = 22.39 nM
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CP0410101
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-8-[(3R,4S,6R)-4-[butan-2-yl(cyclopropylmethyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C53H85ClN2O13
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1
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| 1 |
Ki = 27.54 nM
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CP0445667
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 5-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C46H70ClN3O13
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1
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| 1 |
Ki = 36.31 nM
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CP0430277
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4R)-4-methyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C46H70ClN3O13
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1
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| 1 |
Ki = 48.98 nM
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CP0511367
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S)-4-ethyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H72ClN3O13
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1
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| 1 |
Ki = 66.07 nM
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CP0381079
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C46H73ClN2O13
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1
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| 1 |
Ki = 79.43 nM
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CP0381021
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 4,4-dimethyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H72ClN3O13
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1
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| 1 |
Ki = 79.43 nM
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CP0502052
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4S,5R)-4,5-dimethyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H72ClN3O13
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1
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| 1 |
Ki < 100 nM
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CP0504856
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 2-oxo-1,3-oxazolidine-3-carboxylate
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C45H68ClN3O13
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1
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| 1 |
Ki = 114.82 nM
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CP0436307
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ethyl 3-[[benzyl-[2-oxo-2-[4-(3-phenylprop-2-ynylcarbamoyl)piperidin-1-yl]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C50H50F2N8O6
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1
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| 1 |
Ki = 140 nM
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CP0427984
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ethyl 3-[[benzyl-[2-oxo-2-[[2-oxo-2-(3-phenylprop-2-ynylamino)ethyl]amino]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C46H44F2N8O6
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1
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| 1 |
Ki = 170 nM
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CP0438999
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C47H75ClN2O13
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1
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| 1 |
Ki = 190.55 nM
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CP0507096
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-8-[(3R,4S,6R)-4-[cyclohexyl(methyl)amino]-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-6-[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C52H83ClN2O13
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1
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| 1 |
Ki = 204.17 nM
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CP0448712
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] oxolane-3-carboxylate
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C46H71ClN2O12
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1
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| 1 |
Ki = 213.8 nM
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CP0436306
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ethyl 3-[[benzyl-[2-oxo-2-[(2S)-2-(3-phenylprop-2-ynylcarbamoyl)pyrrolidin-1-yl]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C49H48F2N8O6
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1
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| 1 |
Ki = 260 nM
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CP0403913
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] (4R)-4-(2-methylpropyl)-2-oxo-1,3-oxazolidine-3-carboxylate
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C49H76ClN3O13
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1
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| 1 |
Ki = 275.42 nM
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CP0436308
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ethyl 3-[[benzyl-[2-oxo-2-[[6-oxo-6-(3-phenylprop-2-ynylamino)hexyl]amino]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C50H52F2N8O6
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1
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| 1 |
Ki = 380 nM
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CP0507827
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ethyl 3-[[benzyl-[2-[4-[3-[3-[3-[[1-[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]piperidine-4-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]piperidin-1-yl]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C94H94F4N16O12
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1
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| 1 |
Ki = 400 nM
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CP0436303
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ethyl 3-[[benzyl-[2-[[(2S)-1-[3-[4-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]propanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C88H86F4N16O12
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1
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| 1 |
Ki = 480 nM
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CP0507828
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ethyl 3-[[benzyl-[2-[4-[3-[2-[3-[[1-[2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]acetyl]piperidine-4-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]piperidin-1-yl]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C93H93F4N17O11
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1
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| 1 |
Ki = 500 nM
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CP0449200
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ethyl 3-[[benzyl-[2-[4-[3-[4-[3-[[1-[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]piperidine-4-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]piperidin-1-yl]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C94H94F4N16O12
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1
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| 1 |
Ki = 510 nM
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CP0433399
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ethyl 3-[[benzyl-[2-[[2-[3-[4-[3-[[2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]acetyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C86H82F4N16O12
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1
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| 1 |
Ki = 530 nM
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CP0508616
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 5-ethyl-2-oxo-1,3-oxazolidine-3-carboxylate
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C47H72ClN3O13
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1
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| 1 |
Ki = 562.34 nM
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CP0436309
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ethyl 3-[[benzyl-[2-oxo-2-[[4-oxo-4-(3-phenylprop-2-ynylamino)butyl]amino]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C48H48F2N8O6
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1
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| 1 |
Ki = 580 nM
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CP0444487
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ethyl 3-[[benzyl-[2-[[4-[3-[4-[3-[4-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]butanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-4-oxobutyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C90H90F4N16O12
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1
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| 1 |
Ki = 600 nM
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CP0436310
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ethyl 3-[[benzyl-[2-[[6-[3-[4-[3-[6-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]hexanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-6-oxohexyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C94H98F4N16O12
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1
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| 1 |
Ki = 620 nM
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CP0391374
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] cyclopentanecarboxylate
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C47H73ClN2O11
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1
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| 1 |
Ki = 630.96 nM
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CP0507830
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ethyl 3-[[benzyl-[2-[[6-[3-[2-[3-[6-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]hexanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-6-oxohexyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C91H94F4N16O10
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1
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| 1 |
Ki = 700 nM
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CP0386687
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ethyl 3-[[benzyl-[2-[[(2S)-1-[3-[4-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]-3-methylbutanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C92H94F4N16O12
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1
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| 1 |
Ki = 720 nM
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CP0427978
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ethyl 3-[[benzyl-[2-[(2S)-2-[3-[4-[3-[[(2S)-1-[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C92H90F4N16O12
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1
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| 1 |
Ki = 740 nM
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CP0490573
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ethyl 3-[[benzyl-[2-[[(2S)-3-methyl-1-oxo-1-(3-phenylprop-2-ynylamino)butan-2-yl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C49H50F2N8O6
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1
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| 1 |
Ki = 770 nM
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CP0375305
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 2-methyl-1,3-oxazolidine-3-carboxylate
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C46H72ClN3O12
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1
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| 1 |
Ki = 794.33 nM
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CP0427979
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ethyl 3-[[benzyl-[2-[[4-[3-[3-[3-[4-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]butanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-4-oxobutyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C90H90F4N16O12
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1
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| 1 |
Ki = 820 nM
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CP0449135
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ethyl 3-[[benzyl-[2-[[4-[3-[2-[3-[4-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]butanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-4-oxobutyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C87H86F4N16O10
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1
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| 1 |
Ki = 840 nM
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CP0436304
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ethyl 3-[[benzyl-[2-[[2-[(2S)-2-[3-[2-[3-[[(2S)-1-[2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C93H92F4N18O12
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1
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| 1 |
Ki = 850 nM
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CP0427987
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ethyl 3-[[benzyl-[2-[[6-[3-[3-[3-[6-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]hexanoylamino]prop-1-ynyl]phenyl]prop-2-ynylamino]-6-oxohexyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C94H98F4N16O12
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1
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| 1 |
Ki = 930 nM
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CP0436311
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ethyl 3-[[benzyl-[2-[(2S)-2-[3-[3-[3-[[(2S)-1-[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]prop-1-ynyl]phenyl]prop-2-ynylcarbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C92H90F4N16O12
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1
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| 1 |
Ki = 930 nM
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CP0427988
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ethyl 3-[[benzyl-[2-[[2-[3-[2-[3-[[2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]acetyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C83H78F4N16O10
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1
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| 1 |
Ki = 1000 nM
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CP0433400
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ethyl 3-[[benzyl-[2-[[2-[3-[3-[3-[[2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]acetyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C86H82F4N16O12
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1
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| 1 |
Ki = 1100 nM
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CP0427983
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ethyl 3-[[benzyl-[2-oxo-2-[[(2S)-1-oxo-1-(3-phenylprop-2-ynylamino)propan-2-yl]amino]ethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C47H46F2N8O6
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1
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| 1 |
Ki = 1600 nM
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CP0375096
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] pyrrolidine-1-carboxylate
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C46H72ClN3O11
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1
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| 1 |
Ki = 1621.81 nM
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CP0455132
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 3-methylbutanoate
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C46H73ClN2O11
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1
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| 1 |
Ki = 2041.74 nM
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CP0494596
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 2-oxoimidazolidine-1-carboxylate
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C45H69ClN4O12
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1
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| 1 |
Ki = 2041.74 nM
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CP0436312
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ethyl 3-[[benzyl-[2-[[(2S)-1-[3-[3-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]-3-methylbutanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C92H94F4N16O12
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1
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| 1 |
Ki = 2200 nM
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CP0449136
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ethyl 3-[[benzyl-[2-[[2-[[(2S)-1-[3-[2-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]propanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C87H85F4N17O11
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1
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| 1 |
Ki = 3000 nM
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CP0436305
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ethyl 3-[[benzyl-[2-[[2-[[(2S)-1-[3-[2-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]-3-methylbutanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C91H93F4N17O11
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1
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| 1 |
Ki = 3300 nM
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CP0381020
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] 3-methyl-2-oxoimidazolidine-1-carboxylate
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C46H71ClN4O12
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1
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| 1 |
Ki = 4677.35 nM
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CP0490571
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ethyl 3-[[benzyl-[2-[[(2S)-1-[3-[3-[3-[[(2S)-2-[[2-[benzyl-[[8-[(2,6-difluorophenyl)methyl]-6-ethoxycarbonyl-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidin-3-yl]methyl]amino]acetyl]amino]propanoyl]amino]prop-1-ynyl]phenyl]prop-2-ynylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]methyl]-8-[(2,6-difluorophenyl)methyl]-2-[4-(ethylcarbamoylamino)phenyl]-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylate
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C88H86F4N16O12
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1
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| 1 |
Ki = 5300 nM
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CP0415934
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[(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-trioxo-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl] morpholine-4-carboxylate
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C46H72ClN3O12
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1
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| 1 |
Ki = 5623.41 nM
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CP0430671
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(1S,2R,5R,6S,7S,8R,9S,11R,13R,14R)-15-[2-(4-chlorophenyl)ethyl]-2-ethyl-6-hydroxy-8-[(3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,12,16-trione
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C41H65ClN2O10
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1
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| 1 |
Ki = 10000 nM
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