Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 3-[[benzyl(methyl)amino]methyl]-8-[(2,6-difluorophenyl)methyl]-5-oxo-2-[4-(prop-2-ynylcarbamoylamino)phenyl]imidazo[1,2-a]pyrimidine-6-carboxylate
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 PubChem ID
CID: 44434386
Canonical SMILES
CCOC(=O)c1cn(Cc2c(F)cccc2F)c2nc(c(CN(C)Cc3ccccc3)n2c1=O)-c1ccc(NC(=O)NCC#C)cc1
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Compound Formula C35H32F2N6O4
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 676.08 nM
   TI
   LI
   LO
   TS
2
Ki = 1.349 nM
   TI
   LI
   LO
   TS