General Information of the Compound
Compound ID
CP0486698
Compound Name
ethyl 2-(4-acetamidophenyl)-7-benzyl-3-[[benzyl(methyl)amino]methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate
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Structure
Formula
C34H33N3O4S
Molecular Weight
579.722
Canonical SMILES
CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(C)=O)cc1
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InChI
InChI=1S/C34H33N3O4S/c1-4-41-34(40)29-22-37(20-25-13-9-6-10-14-25)33-30(31(29)39)28(21-36(3)19-24-11-7-5-8-12-24)32(42-33)26-15-17-27(18-16-26)35-23(2)38/h5-18,22H,4,19-21H2,1-3H3,(H,35,38)
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InChIKey
JKMFUJVIEMMGEA-UHFFFAOYSA-N
Physicochemical Property
logP
6.5454
Rotatable Bonds
10
Heavy Atom Count
42
Polar Areas
80.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44413066
ChEMBL ID
CHEMBL211098
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01836, Gonadotropin-releasing hormone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2 nM
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