Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-Chloro-2-oxo-4-[2-((R)-6-trifluoromethyl-piperidin-2-yl)-ethoxy]-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide
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 PubChem ID
CID: 10077523
SID: 15063002
Canonical SMILES
Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCC[C@@H](N2)C(F)(F)F)c2cc(C(=O)Nc3ccncn3)c(Cl)cc2[nH]c1=O
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Compound Formula C31H31ClF3N5O3
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 18 nM
   TI
   LI
   LO
   TS