Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-(1-hydroxy-2-methylpropyl)-2-(4-isobutyrylamidophenyl)-4-oxothieno[2,3-b]pyridine
    Show/Hide
 PubChem ID
CID: 11592777
SID: 16760967
Canonical SMILES
CC(C)C(O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1
    Show/Hide
Compound Formula C37H39F2N3O3S
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS