| Compound ID |
Compound Name |
Compound Formula |
|
CP0240168
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecahydroxy-19,22,28-tris(hydroxymethyl)-42-[(4-hydroxyphenyl)methyl]-16-(2-methylpropyl)-13-(2-methylsulfanylethyl)-45-propan-2-yl-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecazabicyclo[23.22.4]henpentaconta-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaen-36-yl]-hydroxymethylidene]amino]-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-4-[(2S,3S)-1-[(2S,3S)-1-[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]imino-1-hydroxy-3-methylpentan-2-yl]imino-1-hydroxy-3-methylpentan-2-yl]imino-4-hydroxybutanoic acid
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|
C109H159N25O32S5
|
1
|
| 1 |
IC50 = 0.023 nM
|
|
|
|
CP0155304
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(butane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C28H37FN2O7S
|
1
|
| 1 |
IC50 = 0.044 nM
|
|
|
|
CP0113237
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[propyl-(4,4,4-trifluoro-butane-1-sulfonyl)-amino]-ethyl}-pyrrolidine-3-carboxylic acid
Show/Hide
|
C28H34F4N2O7S
|
1
|
| 1 |
IC50 = 0.055 nM
|
|
|
|
CP0048714
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro-propane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C27H34ClFN2O7S
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
|
CP0155329
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(hexane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid
Show/Hide
|
C30H41FN2O7S
|
1
|
| 1 |
IC50 = 0.077 nM
|
|
|
|
CP0084273
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H39FN2O7S
|
1
|
| 1 |
IC50 = 0.078 nM
|
|
|
|
CP0452000
|
4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H38N2O6
|
2
|
| 1 |
IC50 = 0.11 nM
|
|
|
| 2 |
Ki = 0.069 nM
|
|
|
|
CP0356826
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-[2-(2-oxo-pyrrolidin-1-yl)-ethyl]-pyrrolidine-3-carboxylic acid
Show/Hide
|
C28H41N3O6
|
1
|
| 1 |
IC50 = 0.17 nM
|
|
|
|
CP0041541
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyridin-2-yl-ethyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H39N3O5
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
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CP0307521
|
(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C30H46N2O6
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0328005
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H46N2O5
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0104972
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(1S,4S,7S,10R,13S,16R,19S,22R,25R,28R,31S,36R,39S,42R,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-19,22,28-tris(hydroxymethyl)-42-[(4-hydroxyphenyl)methyl]-16-(2-methylpropyl)-13-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-45-propan-2-yl-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecazabicyclo[23.22.4]henpentacontane-36-carbonyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C109H159N25O32S5
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0435970
|
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(butylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C20H22Br2N6O4S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0511248
|
4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
|
C32H34N8O8S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0430251
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
Show/Hide
|
C27H28BrN5O5S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0435966
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-chloro-5-methoxyphenoxy)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C20H22BrClN6O6S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0415199
|
ACT-064992
Show/Hide
|
C19H20Br2N6O4S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0395394
|
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C27H34N2O6
|
1
|
| 1 |
IC50 = 0.55 nM
|
|
|
|
CP0298518
|
3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide
Show/Hide
|
C28H27N3O7S
|
1
|
| 1 |
IC50 = 0.55 nM
|
|
|
|
CP0420874
|
2-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxyethyl N-pyridin-2-ylcarbamate
Show/Hide
|
C31H35N7O8S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0249832
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-amine
Show/Hide
|
C24H23BrN6O4S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
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CP0430883
|
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C18H18Br2N6O4S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0464147
|
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-propyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C28H36N2O6
|
1
|
| 1 |
IC50 = 0.81 nM
|
|
|
|
CP0352140
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H44N2O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0381696
|
4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
|
C33H35N7O8S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0486392
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
|
C31H31N7O8S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0530289
|
N,3,3-trimethyl-N-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]butanamide
Show/Hide
|
C26H28N4O5S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
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CP0435982
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(3-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C24H23BrN6O6S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0190745
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyrazol-1-yl-ethyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C27H38N4O5
|
1
|
| 1 |
IC50 = 1.06 nM
|
|
|
|
CP0498848
|
(S)-[(S)-1-(2,6-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0477081
|
N-[5-(2-methoxyphenoxy)-6-[2-(5-methylsulfanylpyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C30H29N7O6S2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0491713
|
N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]butane-1-sulfonamide
Show/Hide
|
C20H21Br2N5O4S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0146575
|
3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide
Show/Hide
|
C27H25N3O7S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0435981
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-chlorophenyl)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C19H20BrClN6O4S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0405216
|
(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26ClFN4O4
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0435983
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-morpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C28H30BrN7O7S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0460977
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-chlorophenyl)pyrimidin-4-amine
Show/Hide
|
C23H20BrClN6O4S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0476536
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-chloro-5-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C24H22BrClN6O6S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0396129
|
2-(6-acetyl-1-methylindol-3-yl)-2-(1,3-benzodioxol-5-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C28H26N2O7S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0430886
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
Show/Hide
|
C31H30BrN7O6S
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
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CP0467200
|
N-[4-(3,5-dioxohexyl)phenyl]-3-[2-[2-[2-[2-[methyl-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethoxy]propanamide
Show/Hide
|
C43H49N5O12S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0446205
|
N-(benzylsulfamoyl)-5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-amine
Show/Hide
|
C23H20Br2N6O4S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0453518
|
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(methylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C17H16Br2N6O4S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
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CP0499894
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(butylsulfamoyl)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
|
C25H27BrN8O6S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
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CP0405870
|
2-[4-[[2-(1,3-benzodioxol-5-yl)-2-(6-carbamoyl-1-methylindol-3-yl)acetyl]sulfamoyl]phenyl]acetic acid
Show/Hide
|
C27H23N3O8S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
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CP0406450
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26Cl2N4O4
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
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CP0368400
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
|
C28H25BrN8O6S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
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CP0511495
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(3-methoxyphenoxy)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
|
C20H23BrN6O6S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
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CP0428670
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
|
C30H30N8O8S
|
1
|
| 1 |
IC50 = 2 nM
|
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|
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CP0395678
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrazin-2-ylpyrimidin-4-amine
Show/Hide
|
C28H25BrN8O6S
|
1
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| 1 |
IC50 = 2.1 nM
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|
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CP0249256
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C29H26BrN7O6S
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
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CP0430880
|
N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]propane-1-sulfonamide
Show/Hide
|
C19H19Br2N5O4S
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1
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| 1 |
IC50 = 2.2 nM
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|
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CP0076043
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(2S)-2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C27H26N2O7S
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2
|
| 1 |
IC50 = 2.2 nM
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|
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| 2 |
Ki = 2.2 nM
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CP0430884
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-ethylphenyl)pyrimidin-4-amine
Show/Hide
|
C25H25BrN6O4S
|
1
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| 1 |
IC50 = 2.3 nM
|
|
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CP0270554
|
3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid
Show/Hide
|
C28H27N3O6S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
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CP0504800
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
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CP0193973
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
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CP0511879
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H27F3N4O5
|
1
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| 1 |
IC50 = 2.5 nM
|
|
|
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CP0453962
|
N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]morpholine-4-sulfonamide
Show/Hide
|
C20H20Br2N6O5S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
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CP0486691
|
N-[6-[2-(5-chloropyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C29H26ClN7O6S
|
1
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| 1 |
IC50 = 2.8 nM
|
|
|
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CP0480971
|
(S)-[(S)-5-Biphenyl-3-yl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C37H34N4O5
|
1
|
| 1 |
IC50 = 3 nM
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CP0423706
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N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-[2-[5-(trifluoromethyl)pyrimidin-2-yl]oxyethoxy]pyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H26F3N7O6S
|
1
|
| 1 |
IC50 = 3 nM
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CP0512447
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-ethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C33H34N4O5
|
1
|
| 1 |
IC50 = 3.1 nM
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CP0435980
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N-[5-(2-methoxyphenoxy)-6-[2-(5-methoxypyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H29N7O7S
|
1
|
| 1 |
IC50 = 3.2 nM
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CP0430244
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5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine
Show/Hide
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C16H14Br2N6O4S
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1
|
| 1 |
IC50 = 3.4 nM
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|
|
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CP0460978
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-amine
Show/Hide
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C29H26BrN7O6S
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1
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| 1 |
IC50 = 3.4 nM
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CP0401637
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(S)-[(S)-1-(4-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C34H36N4O4
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1
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| 1 |
IC50 = 3.5 nM
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CP0409355
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H27FN4O4
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1
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| 1 |
IC50 = 3.5 nM
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CP0482381
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-propan-2-ylphenyl)pyrimidin-4-amine
Show/Hide
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C26H27BrN6O4S
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1
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| 1 |
IC50 = 3.6 nM
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CP0401415
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(S)-[(S)-1-(2,3-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H26F2N4O4
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1
|
| 1 |
IC50 = 3.7 nM
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CP0486689
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-N-(propylsulfamoyl)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C24H25BrN8O6S
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1
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| 1 |
IC50 = 3.8 nM
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CP0498902
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-phenethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C31H30N4O4
|
1
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| 1 |
IC50 = 3.9 nM
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CP0415086
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C28H27NO9
|
1
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| 1 |
IC50 = 4.1 nM
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CP0265839
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3-[(1S)-1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylic acid
Show/Hide
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C27H24N2O8S
|
2
|
| 1 |
IC50 = 4.2 nM
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| 2 |
Ki = 4.2 nM
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CP0249829
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]butane-1-sulfonamide
Show/Hide
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C25H26BrN7O6S
|
1
|
| 1 |
IC50 = 4.3 nM
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CP0262170
|
4-tert-butyl-N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]benzenesulfonamide
Show/Hide
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C31H31N7O6S
|
1
|
| 1 |
IC50 = 4.3 nM
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CP0477051
|
4-[[benzyl(methyl)sulfamoyl]amino]-5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidine
Show/Hide
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C24H22Br2N6O4S
|
1
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| 1 |
IC50 = 4.3 nM
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CP0453703
|
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(cyclopropylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C19H18Br2N6O4S
|
1
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| 1 |
IC50 = 4.4 nM
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CP0427898
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N-[4-(3,5-dioxohexyl)phenyl]-3-[2-[2-[2-[2-[4-[2-[methyl-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]amino]-2-oxoethyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanamide
Show/Hide
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C51H57N5O13S
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1
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| 1 |
IC50 = 4.6 nM
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CP0453050
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H30N4O5
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1
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| 1 |
IC50 = 4.6 nM
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CP0436711
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-methyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C26H32N2O6
|
1
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| 1 |
IC50 = 4.88 nM
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CP0448951
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C26H21N9O5S
|
1
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| 1 |
IC50 = 5 nM
|
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CP0481080
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H30N4O4
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1
|
| 1 |
IC50 = 5 nM
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CP0405869
|
3-[1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylic acid
Show/Hide
|
C27H24N2O8S
|
1
|
| 1 |
IC50 = 5.3 nM
|
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CP0373459
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C28H27NO9
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
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CP0418841
|
(S)-[(S)-1-(3-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H27ClN4O4
|
1
|
| 1 |
IC50 = 5.8 nM
|
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CP0425848
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H27FN4O4
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
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CP0401639
|
(S)-[(S)-1-(2,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
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CP0440102
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3,4-dimethoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C29H29NO10
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
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CP0404036
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H32N4O5
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
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CP0453465
|
(S)-((S)-1-Benzyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H28N4O4
|
1
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| 1 |
IC50 = 6.4 nM
|
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CP0504149
|
(S)-[(S)-1-(3-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H27BrN4O4
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
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CP0418826
|
(S)-[(S)-1-(3,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
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CP0425849
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,4-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
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CP0499255
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2H-tetrazol-5-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C25H24N8O4
|
1
|
| 1 |
IC50 = 6.6 nM
|
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CP0445448
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C33H34N4O4
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
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CP0452993
|
(S)-[(S)-1-(2,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
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1
|
| 1 |
IC50 = 6.7 nM
|
|
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CP0509170
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H27FN4O4
|
1
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| 1 |
IC50 = 6.7 nM
|
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CP0430885
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-3-phenylpropane-1-sulfonamide
Show/Hide
|
C30H28BrN7O6S
|
1
|
| 1 |
IC50 = 6.7 nM
|
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CP0464442
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-pentafluorophenylmethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C30H23F5N4O4
|
1
|
| 1 |
IC50 = 6.8 nM
|
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CP0547780
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-phenylpyrimidin-4-amine
Show/Hide
|
C23H21BrN6O4S
|
1
|
| 1 |
IC50 = 6.8 nM
|
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CP0490406
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-hydroxy-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C25H26N4O5
|
1
|
| 1 |
IC50 = 6.9 nM
|
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CP0149984
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C24H23BrN6O6S
|
1
|
| 1 |
IC50 = 6.9 nM
|
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CP0446095
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-(2-methoxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C27H29BrN6O8S
|
1
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| 1 |
IC50 = 6.9 nM
|
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CP0505980
|
4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
|
C34H31N7O7S
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1
|
| 1 |
IC50 = 7 nM
|
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CP0453935
|
4-[[benzyl(methyl)sulfamoyl]amino]-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidine
Show/Hide
|
C29H27BrN8O6S
|
1
|
| 1 |
IC50 = 7 nM
|
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CP0428486
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
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CP0441677
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(4-fluoro-3-methyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H31FN4O5
|
1
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| 1 |
IC50 = 7.3 nM
|
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CP0493450
|
(S)-((S)-1-Cyclopropylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C27H28N4O4
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1
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| 1 |
IC50 = 7.3 nM
|
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CP0384738
|
4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid methyl ester
Show/Hide
|
C32H30N4O6
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1
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| 1 |
IC50 = 7.4 nM
|
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CP0502159
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methoxy-ethoxymethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C27H30N4O6
|
1
|
| 1 |
IC50 = 7.5 nM
|
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CP0404038
|
(S)-[(S)-5-(3-Butyl-phenyl)-1-(2-chloro-6-fluoro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C34H34ClFN4O4
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1
|
| 1 |
IC50 = 7.6 nM
|
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CP0485190
|
N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-N'-methyl-N'-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]pentanediamide
Show/Hide
|
C62H86N6O20S
|
1
|
| 1 |
IC50 = 7.7 nM
|
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CP0395680
|
N-[6-[2-(5-cyclopropylpyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C32H31N7O6S
|
1
|
| 1 |
IC50 = 7.7 nM
|
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CP0130277
|
(S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C36H29F3N4O4
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
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CP0404037
|
(S)-[(S)-5-(3-Butyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C35H38N4O5
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
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CP0503016
|
(S)-[(S)-1-(3,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
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CP0435975
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-N-(methylsulfamoyl)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
|
C22H21BrN8O6S
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0065655
|
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
Show/Hide
|
C27H29N5O6S
|
4
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 40 nM
|
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|
| 3 |
IC50 = 45 nM
|
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| 4 |
Ki = 8 nM
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CP0501765
|
3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenylcarbamoyl]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-N-[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-propionamide
Show/Hide
|
C50H63N5O15S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
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CP0362696
|
N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C29H27N7O6S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
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CP0391251
|
2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C27H26N2O7S
|
1
|
| 1 |
IC50 = 8.7 nM
|
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CP0535041
|
2-(1,3-benzodioxol-5-yl)-2-[6-(methoxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C28H28N2O7S
|
1
|
| 1 |
IC50 = 8.8 nM
|
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CP0372656
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H30N4O4
|
1
|
| 1 |
IC50 = 8.9 nM
|
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CP0471475
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H27F3N4O4
|
1
|
| 1 |
IC50 = 9.1 nM
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CP0471481
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H29FN4O5
|
1
|
| 1 |
IC50 = 9.1 nM
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CP0486690
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]propane-1-sulfonamide
Show/Hide
|
C24H24BrN7O6S
|
1
|
| 1 |
IC50 = 9.4 nM
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CP0423735
|
6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
|
C23H23BrN8O6S
|
1
|
| 1 |
IC50 = 9.9 nM
|
|
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CP0439363
|
(S)-[(S)-1-(2-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H27ClN4O4
|
1
|
| 1 |
IC50 = 10.2 nM
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CP0494787
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-5-(3-methoxy-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H32N4O6
|
1
|
| 1 |
IC50 = 10.2 nM
|
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CP0477080
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
|
C27H22BrN7O6S
|
1
|
| 1 |
IC50 = 10.4 nM
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CP0493865
|
5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
|
C26H23N5O6S
|
1
|
| 1 |
IC50 = 11 nM
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|
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CP0497793
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H27F3N4O5
|
1
|
| 1 |
IC50 = 11 nM
|
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CP0441509
|
2-(1,3-benzodioxol-5-yl)-2-(6-cyano-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C27H23N3O6S
|
1
|
| 1 |
IC50 = 11 nM
|
|
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CP0496089
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 11.8 nM
|
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|
CP0504825
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]-2-oxoacetic acid
Show/Hide
|
C28H25NO10
|
1
|
| 1 |
IC50 = 12 nM
|
|
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|
CP0496417
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-4-ylcarbamate
Show/Hide
|
C31H31N7O8S
|
1
|
| 1 |
IC50 = 12 nM
|
|
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CP0507739
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
|
C27H21N7O6S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
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CP0193626
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C24H24N4O4
|
1
|
| 1 |
IC50 = 12.3 nM
|
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CP0452881
|
4-tert-Butyl-N-[6-(4-methoxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C30H31N5O6S
|
1
|
| 1 |
IC50 = 13 nM
|
|
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CP0505707
|
4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
|
C34H36N6O8S
|
1
|
| 1 |
IC50 = 13 nM
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|
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|
CP0509179
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide
Show/Hide
|
C27H21N7O7S
|
1
|
| 1 |
IC50 = 13 nM
|
|
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CP0401635
|
(S)-((S)-1-Carboxymethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C25H24N4O6
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0199771
|
(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C34H33F3N4O4
|
1
|
| 1 |
IC50 = 13.9 nM
|
|
|
|
CP0497256
|
3-[2-((1R,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-2,2-dimethyl-propionic acid
Show/Hide
|
C31H33NO9
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0372766
|
N-[3-[6-[(4-tert-butylphenyl)sulfonylamino]-2-cyclopropyl-5-(2-methoxyphenoxy)pyrimidin-4-yl]oxypropyl]thiophene-2-sulfonamide
Show/Hide
|
C31H36N4O7S3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0503871
|
4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
|
C33H30N8O7S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0395679
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]ethanesulfonamide
Show/Hide
|
C23H22BrN7O6S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0547785
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-cyclopropyl-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C27H27BrN6O6S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0494075
|
2-(1,3-benzodioxol-5-yl)-2-(6-fluoro-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
|
C26H23FN2O6S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0375923
|
5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C27H31N5O7S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
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CP0509449
|
(S)-[(S)-5-Biphenyl-3-yl-1-(2,6-dichloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C36H30Cl2N4O4
|
1
|
| 1 |
IC50 = 16.9 nM
|
|
|
|
CP0384016
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H27F3N4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0439605
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-phenyl-propyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H32N4O4
|
1
|
| 1 |
IC50 = 17.1 nM
|
|
|
|
CP0497791
|
(S)-[(S)-1-(4-tert-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C34H36N4O4
|
1
|
| 1 |
IC50 = 17.1 nM
|
|
|
|
CP0095826
|
(S)-(3,5-Dimethyl-phenoxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H27F3N2O4
|
1
|
| 1 |
IC50 = 17.2 nM
|
|
|
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CP0504135
|
(S)-[(S)-1-(4-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H27ClN4O4
|
1
|
| 1 |
IC50 = 17.3 nM
|
|
|
|
CP0415198
|
N-[5-(2-methoxyphenoxy)-6-[2-(5-methylpyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C30H29N7O6S
|
1
|
| 1 |
IC50 = 17.8 nM
|
|
|
|
CP0399397
|
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C25H27N5O7S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0448946
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
|
C32H32N6O8S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0514035
|
ethyl 3-[1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylate
Show/Hide
|
C29H28N2O8S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0453427
|
(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C37H42N4O4
|
1
|
| 1 |
IC50 = 18.3 nM
|
|
|
|
CP0430304
|
(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid
Show/Hide
|
C32H28ClFN2O4
|
1
|
| 1 |
IC50 = 18.9 nM
|
|
|
|
CP0376892
|
5-Isopropyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C27H36N6O8S2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0384710
|
(S)-(4,6-Diethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C26H28N4O4
|
1
|
| 1 |
IC50 = 20.5 nM
|
|
|
|
CP0500927
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid
Show/Hide
|
C32H28Cl2N2O4
|
1
|
| 1 |
IC50 = 20.5 nM
|
|
|
|
CP0156307
|
CHEBI:2965
Show/Hide
|
C31H42N6O7
|
1
|
| 1 |
IC50 = 20.5 nM
|
|
|
|
CP0449640
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-3-ylcarbamate
Show/Hide
|
C31H31N7O8S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0436708
|
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid
Show/Hide
|
C25H30N2O6
|
1
|
| 1 |
IC50 = 21.3 nM
|
|
|
|
CP0467199
|
3-[4-[2-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]phenyl]-N-methyl-N-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]propanamide
Show/Hide
|
C52H59N5O13S
|
1
|
| 1 |
IC50 = 21.6 nM
|
|
|
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CP0002228
|
(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C22H22N2O4
|
1
|
| 1 |
IC50 = 21.7 nM
|
|
|
|
CP0440064
|
4-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-butyric acid
Show/Hide
|
C30H31NO9
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0483059
|
5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C29H33N5O7S3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0436737
|
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C26H23N5O6S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0481093
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide
Show/Hide
|
C29H25N7O7S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0498131
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
|
C28H25N9O5S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0428535
|
(S)-(4,6-Dimethoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C24H24N4O6
|
1
|
| 1 |
IC50 = 23.4 nM
|
|
|
|
CP0374283
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-hexyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C29H34N4O4
|
1
|
| 1 |
IC50 = 23.7 nM
|
|
|
|
CP0087311
|
2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-propylphenoxy]-N-(4-propan-2-ylphenyl)sulfonylacetamide
Show/Hide
|
C38H42N4O6S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0383955
|
5-Isopropyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
|
C28H27N5O6S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0375999
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-(3-trifluoromethyl-phenyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H29F3N4O5
|
1
|
| 1 |
IC50 = 24.9 nM
|
|
|
|
CP0405194
|
(S)-[(S)-5-(3-Chloro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C31H29ClN4O5
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0271450
|
N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C25H25N5O6S
|
1
|
| 1 |
IC50 = 25.7 nM
|
|
|
|
CP0503015
|
(S)-[(S)-1-(4-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H27BrN4O4
|
1
|
| 1 |
IC50 = 25.8 nM
|
|
|
|
CP0523285
|
5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C28H27N5O6S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0428778
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
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C29H25N7O6S2
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1
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| 1 |
IC50 = 27 nM
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CP0500643
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2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-[4-methoxy-2-(2H-tetrazol-5-ylmethoxy)phenyl]-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C28H27N5O7
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1
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| 1 |
IC50 = 29 nM
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CP0418845
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-m-tolyloxy-acetic acid
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C31H26Cl2N2O4
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1
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| 1 |
IC50 = 29 nM
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CP0425850
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(R)-5-(2-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H29FN4O5
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1
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| 1 |
IC50 = 30.3 nM
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CP0500970
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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C31H30N4O4
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1
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| 1 |
IC50 = 30.5 nM
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CP0483604
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2-[2-[(1S,3R)-3-(1,3-benzodioxol-5-yl)-6-ethoxy-2-(2H-tetrazol-5-yl)-1,3-dihydroisoindol-1-yl]-5-methoxyphenoxy]acetic acid
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C27H25N5O7
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1
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| 1 |
IC50 = 31 nM
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CP0134357
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3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid
Show/Hide
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C29H28N2O7S
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1
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| 1 |
IC50 = 32 nM
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CP0398021
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2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(4-methylphenyl)sulfonylacetamide
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C26H24N2O6S
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1
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| 1 |
IC50 = 34 nM
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CP0509219
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4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
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C35H32N6O7S
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1
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| 1 |
IC50 = 35 nM
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CP0502302
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Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid
Show/Hide
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C32H37N3O5
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1
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| 1 |
IC50 = 38 nM
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CP0380905
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4-tert-Butyl-N-[2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C30H30N4O6S
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1
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| 1 |
IC50 = 38 nM
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CP0453934
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-methoxy-5-(2-methoxyphenoxy)pyrimidin-4-amine
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C25H25BrN6O7S
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1
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| 1 |
IC50 = 40 nM
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CP0444716
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N-[[5-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]-N,3,3-trimethylbutanamide
Show/Hide
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C44H56N4O11S
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1
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| 1 |
IC50 = 44.9 nM
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CP0460882
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5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
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C27H35N5O7S2
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1
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| 1 |
IC50 = 45 nM
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CP0392962
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-propylcarbamoylmethyl-pyrrolidine-3-carboxylic acid
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C24H28N2O6
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1
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| 1 |
IC50 = 45.3 nM
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CP0492667
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4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-yl}-butyric acid
Show/Hide
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C27H28N4O6
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1
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| 1 |
IC50 = 45.9 nM
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CP0494074
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2-(1,3-benzodioxol-5-yl)-2-(6-chloro-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
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C26H23ClN2O6S
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1
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| 1 |
IC50 = 46 nM
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CP0510035
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
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C32H28Cl2N2O6
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1
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| 1 |
IC50 = 46.2 nM
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CP0460777
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4-tert-Butyl-N-[2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
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C29H38N4O7S2
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1
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| 1 |
IC50 = 48 nM
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CP0452839
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5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
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C26H33N5O7S2
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1
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| 1 |
IC50 = 50 nM
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CP0454669
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C26H34N6O8S2
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1
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| 1 |
IC50 = 51 nM
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CP0419746
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C29H29N5O6S
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1
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| 1 |
IC50 = 51 nM
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CP0439373
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5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
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C27H26N6O6S
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1
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| 1 |
IC50 = 53 nM
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CP0439360
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-acetic acid
Show/Hide
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C25H24N6O3
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1
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| 1 |
IC50 = 55.9 nM
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CP0492843
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C26H25NO7
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1
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| 1 |
IC50 = 58 nM
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CP0918803
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(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene-1-carboxylic acid
Show/Hide
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C26H24N6O5
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1
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| 1 |
IC50 = 58.8 nM
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CP0394293
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
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C30H31N5O5S
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1
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| 1 |
IC50 = 59 nM
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CP0415579
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N-[2-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxyethyl]thiophene-2-sulfonamide
Show/Hide
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C31H32N6O7S3
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1
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| 1 |
IC50 = 64 nM
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CP0407814
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(3,4,5-trimethoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C28H29NO8
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1
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| 1 |
IC50 = 66 nM
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CP0398618
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4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-benzenesulfonamide
Show/Hide
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C31H28N6O7S
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1
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| 1 |
IC50 = 66 nM
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CP0460298
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3-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-2,2-dimethyl-propionic acid
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C31H33NO9
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1
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| 1 |
IC50 = 68 nM
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CP0445446
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-5-phenyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-5-yl)-acetic acid
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C23H23N3O4
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1
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| 1 |
IC50 = 69.8 nM
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CP0460979
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-1-phenylmethanesulfonamide
Show/Hide
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C28H24BrN7O6S
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1
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| 1 |
IC50 = 73 nM
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CP0463064
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5-Isobutyl-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-amide
Show/Hide
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C37H42N4O6S2
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1
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| 1 |
IC50 = 75 nM
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CP0502525
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2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C26H25NO7
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1
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| 1 |
IC50 = 77 nM
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CP0460892
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5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C32H37N5O7S2
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1
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| 1 |
IC50 = 77 nM
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CP0480701
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5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C27H35N5O7S2
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1
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| 1 |
IC50 = 80 nM
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CP0460798
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5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(propane-1-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C28H37N5O7S2
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1
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| 1 |
IC50 = 82 nM
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CP0394394
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(S)-((S)-1-Cyclohexylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H34N4O4
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1
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| 1 |
IC50 = 83.4 nM
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CP0423167
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4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-benzenesulfonamide
Show/Hide
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C31H28N6O6S2
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1
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| 1 |
IC50 = 84 nM
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CP0422122
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2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C28H27NO9
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1
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| 1 |
IC50 = 85 nM
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CP0448950
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4-tert-Butyl-N-[6-but-2-ynyloxy-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C29H29N5O5S
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1
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| 1 |
IC50 = 85 nM
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CP0498524
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N-[3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxypropyl]thiophene-2-sulfonamide
Show/Hide
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C32H34N6O7S3
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1
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| 1 |
IC50 = 86 nM
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CP0448403
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-yl)-acetic acid
Show/Hide
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C24H25N3O3
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1
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| 1 |
IC50 = 91.7 nM
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CP0405736
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5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C25H21N5O5S
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1
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| 1 |
IC50 = 94 nM
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CP0435648
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2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(4-methoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C26H25NO6
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1
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| 1 |
IC50 = 95 nM
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CP0394581
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3,4-dimethoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C29H29NO10
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1
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| 1 |
IC50 = 96 nM
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CP0430468
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(4-methoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C26H25NO6
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1
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| 1 |
IC50 = 96 nM
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CP0372935
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
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C26H24N6O5S
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1
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| 1 |
IC50 = 96 nM
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CP0501088
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C28H27N5O5S
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1
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| 1 |
IC50 = 97 nM
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CP0491681
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H27F3N4O5
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1
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| 1 |
IC50 = 98.6 nM
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CP0495473
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(S)-(3-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H23Cl3N2O4
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1
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| 1 |
IC50 = 101 nM
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CP0401595
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(S)-((S)-1-Biphenyl-4-ylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C36H32N4O4
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1
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| 1 |
IC50 = 102 nM
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CP0401636
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H27F3N4O4
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1
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| 1 |
IC50 = 104 nM
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CP0509626
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C28H27NO9
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1
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| 1 |
IC50 = 110 nM
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CP0449870
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(S)-[(S)-5-Cyclohexyl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C31H36N4O5
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1
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| 1 |
IC50 = 112 nM
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CP0453936
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]methanesulfonamide
Show/Hide
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C22H20BrN7O6S
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1
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| 1 |
IC50 = 113 nM
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CP0403654
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C33H40N6O8S2
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1
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| 1 |
IC50 = 116 nM
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CP0402103
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4-tert-Butyl-N-[2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C28H36N4O7S2
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1
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| 1 |
IC50 = 119 nM
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CP0430297
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2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-5-propoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
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C27H27NO6
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1
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| 1 |
IC50 = 120 nM
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CP0383292
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
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C26H29N5O6S
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1
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| 1 |
IC50 = 121 nM
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CP0502821
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4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid
Show/Hide
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C31H28N4O6
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1
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| 1 |
IC50 = 123 nM
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CP0419387
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C27H25N5O5S
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1
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| 1 |
IC50 = 125 nM
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CP0497165
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C30H30N4O6S
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1
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| 1 |
IC50 = 125 nM
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CP0504757
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-morpholin-4-yl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C29H33N5O5
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1
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| 1 |
IC50 = 126 nM
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CP0425842
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3-methoxy-phenoxy)-acetic acid
Show/Hide
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C31H26Cl2N2O5
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1
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| 1 |
IC50 = 129 nM
|
|
|
|
CP0505932
|
4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy-but-2-ynyloxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C35H33N5O6S
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0376893
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C28H38N6O8S2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0441463
|
(S)-[(S)-1-(2-Cyclohexyl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C31H36N4O4
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0502030
|
4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
|
C29H34N4O7S
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
|
CP0504787
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-p-tolyloxy-acetic acid
Show/Hide
|
C31H26Cl2N2O4
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0375994
|
Butyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester
Show/Hide
|
C33H36N6O7S
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0423204
|
4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-enyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C30H33N5O5S
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0374617
|
5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
|
C23H24N4O6S
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0448112
|
4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
|
C29H28N4O5S
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0501127
|
5-Methyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C26H28N6O7S2
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0428466
|
4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
|
C28H27N5O5S
|
1
|
| 1 |
IC50 = 186 nM
|
|
|
|
CP0415197
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]morpholine-4-sulfonamide
Show/Hide
|
C25H25BrN8O7S
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0505716
|
Butyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester
Show/Hide
|
C30H36N6O8S
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0376120
|
4-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
|
C34H32N8O7S
|
1
|
| 1 |
IC50 = 204 nM
|
|
|
|
CP0419386
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-phenoxy-acetic acid
Show/Hide
|
C30H24Cl2N2O4
|
1
|
| 1 |
IC50 = 211 nM
|
|
|
|
CP0428498
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-p-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C32H32N4O5
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
|
CP0523284
|
N-[6-[(E)-but-2-enoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
Show/Hide
|
C29H31N5O5S
|
1
|
| 1 |
IC50 = 239 nM
|
|
|
|
CP0467115
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
|
C33H41N5O10S2
|
1
|
| 1 |
IC50 = 261 nM
|
|
|
|
CP0494782
|
(S)-((S)-7-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
|
C26H25ClN2O6
|
1
|
| 1 |
IC50 = 262 nM
|
|
|
|
CP0481012
|
(S)-[(S)-5-(3,5-Dimethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C33H34N4O5
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0486390
|
4-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
|
C35H33N7O7S
|
1
|
| 1 |
IC50 = 293 nM
|
|
|
|
CP0377275
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3,4,5-trimethoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C30H31NO11
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0500243
|
2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-(4-propan-2-ylphenyl)sulfonylacetamide
Show/Hide
|
C41H48N4O6S
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0492866
|
2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3,4,5-trimethoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C30H31NO11
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0449639
|
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
|
C25H22N6O6S
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0480993
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C26H24N6O5S
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0506671
|
5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
|
C24H20N6O5S
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0496661
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-pentyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H36N4O5
|
1
|
| 1 |
IC50 = 355 nM
|
|
|
|
CP0510963
|
4-tert-butyl-N-[5-(2-methoxyphenoxy)-6-prop-2-enoxy-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
|
C28H29N5O5S
|
1
|
| 1 |
IC50 = 373 nM
|
|
|
|
CP0436744
|
(S)-(5-Methoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C23H22N4O5
|
1
|
| 1 |
IC50 = 384 nM
|
|
|
|
CP0430432
|
(S)-[(S)-1-(2-Dimethylamino-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C27H31N5O4
|
1
|
| 1 |
IC50 = 387 nM
|
|
|
|
CP0430276
|
(S)-((S)-7,8-Dimethoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
|
C28H30N2O8
|
1
|
| 1 |
IC50 = 443 nM
|
|
|
|
CP0391670
|
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yl]-amide
Show/Hide
|
C22H22N4O6S
|
1
|
| 1 |
IC50 = 452 nM
|
|
|
|
CP0454815
|
4-tert-Butyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C29H34N6O7S2
|
1
|
| 1 |
IC50 = 487 nM
|
|
|
|
CP0420943
|
2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-methylsulfonylacetamide
Show/Hide
|
C33H40N4O6S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0462030
|
2-(1,3-benzodioxol-5-yl)-2-(1-ethylindol-3-yl)-N-(4-propan-2-ylphenyl)sulfonylacetamide
Show/Hide
|
C28H28N2O5S
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0502157
|
4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
|
C25H27N3O6S
|
1
|
| 1 |
IC50 = 561 nM
|
|
|
|
CP0376442
|
5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
|
C24H29N5O7S2
|
1
|
| 1 |
IC50 = 582 nM
|
|
|
|
CP0448917
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C29H34N6O8S3
|
1
|
| 1 |
IC50 = 587 nM
|
|
|
|
CP0404479
|
5-Isobutyl-3H-1lambda*4*-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide
Show/Hide
|
C40H48N4O6S2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0455422
|
(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-1-methyl-6-phenyl-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid
Show/Hide
|
C27H25N5O5
|
1
|
| 1 |
IC50 = 604 nM
|
|
|
|
CP0401606
|
(S)-(3,5-Dimethoxy-phenoxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C26H26N2O6
|
1
|
| 1 |
IC50 = 605 nM
|
|
|
|
CP0471758
|
2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-propan-2-ylsulfonylacetamide
Show/Hide
|
C35H44N4O6S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0421504
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C27H30N6O8S3
|
1
|
| 1 |
IC50 = 724 nM
|
|
|
|
CP0453937
|
N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]methanesulfonamide
Show/Hide
|
C22H21N7O6S
|
1
|
| 1 |
IC50 = 739 nM
|
|
|
|
CP0503872
|
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-cyclohexylcarbamate
Show/Hide
|
C32H38N6O8S
|
1
|
| 1 |
IC50 = 753 nM
|
|
|
|
CP0399704
|
3H-1lambda*4*-Thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide
Show/Hide
|
C36H40N4O6S2
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0430986
|
Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetic acid
Show/Hide
|
C29H31N3O5
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0504944
|
(S)-(5-Bromo-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C22H19BrN4O4
|
1
|
| 1 |
IC50 = 927 nM
|
|
|
|
CP0523834
|
5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C31H35N5O7S2
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0479152
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-(3,4,5-trimethoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C28H29NO8
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0418361
|
4-tert-butyl-N-[5-(2-methoxyphenoxy)-6-(4-phenylmethoxybut-2-ynoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
|
C36H35N5O6S
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0376450
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
|
C34H37N5O10S3
|
1
|
| 1 |
IC50 = 1317 nM
|
|
|
|
CP0421545
|
5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C25H31N5O7S2
|
1
|
| 1 |
IC50 = 1320 nM
|
|
|
|
CP0404589
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C32H38N6O8S2
|
1
|
| 1 |
IC50 = 1385 nM
|
|
|
|
CP0487455
|
(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0448557
|
4-tert-Butyl-N-[6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C30H36N6O7S2
|
1
|
| 1 |
IC50 = 1591 nM
|
|
|
|
CP0503424
|
N-(benzenesulfonyl)-2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]acetamide
Show/Hide
|
C38H42N4O6S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0538965
|
5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C26H27N5O7S3
|
1
|
| 1 |
IC50 = 1850 nM
|
|
|
|
CP0372750
|
5-Methyl-pyridine-2-sulfonic acid {2-benzo[1,3]dioxol-5-ylmethyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C31H29N5O9S3
|
1
|
| 1 |
IC50 = 2190 nM
|
|
|
|
CP0454811
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C31H30N6O7S2
|
1
|
| 1 |
IC50 = 2193 nM
|
|
|
|
CP0490210
|
5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
|
C32H33N5O10S3
|
1
|
| 1 |
IC50 = 2770 nM
|
|
|
|
CP0437101
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C28H26N6O7S3
|
1
|
| 1 |
IC50 = 2838 nM
|
|
|
|
CP0504686
|
2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-5-methoxy-3-(4-methoxyphenyl)-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C25H23NO6
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0456960
|
(S)-((S)-8-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
|
C26H25ClN2O6
|
1
|
| 1 |
IC50 = 3840 nM
|
|
|
|
CP0453075
|
(S)-(3,5-Dimethoxy-phenoxy)-((S)-8-methoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C27H28N2O7
|
1
|
| 1 |
IC50 = 3950 nM
|
|
|
|
CP0453938
|
N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]methanesulfonamide
Show/Hide
|
C18H19N5O6S
|
1
|
| 1 |
IC50 = 4534 nM
|
|
|
|
CP0430877
|
N-[6-[2-(4,6-dimethoxypyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C31H31N7O8S
|
1
|
| 1 |
IC50 = 4775 nM
|
|
|
|
CP0460857
|
4-[4-(tert-butyl)phenylsulfonamido]-2-cyclopropyl-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]pyrimidine
Show/Hide
|
C33H38N4O7S2
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0490188
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
|
C37H41N5O10S2
|
1
|
| 1 |
IC50 = 5115 nM
|
|
|
|
CP0502121
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2-methoxy-phenoxy)-acetic acid
Show/Hide
|
C31H26Cl2N2O5
|
1
|
| 1 |
IC50 = 5920 nM
|
|
|
|
CP0498629
|
(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(5-methylsulfanyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C23H22N4O4S
|
1
|
| 1 |
IC50 = 6600 nM
|
|
|
|
CP0522256
|
4-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]-2-(2-pyrimidinyl)pyrimidine
Show/Hide
|
C34H36N6O7S2
|
1
|
| 1 |
IC50 = 8390 nM
|
|
|
|
CP0376145
|
2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]-2-oxoacetic acid
Show/Hide
|
C28H25NO10
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0421362
|
2-[(1S,3R)-1-[2-(carboxymethoxy)-4-methoxyphenyl]-3-(4-methoxyphenyl)-5-propoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C29H31NO8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448852
|
(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-2-(1H-tetrazol-5-yl)-3-(3,4,5-trimethoxy-phenyl)-2,3-dihydro-1H-isoindole
Show/Hide
|
C27H27N5O6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0503281
|
2-[(1S,3S)-1-[2-(carboxymethoxy)-4-methoxyphenyl]-3-(4-methoxyphenyl)-5-propoxy-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C29H31NO8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0539834
|
2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-[2-(2-hydroxyethoxy)-4-methoxyphenyl]-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C28H29NO8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0405213
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,3-dimethyl-phenoxy)-acetic acid
Show/Hide
|
C32H28Cl2N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0453425
|
(S)-(2-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H23Cl3N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0453464
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4-isopropyl-phenoxy)-acetic acid
Show/Hide
|
C33H30Cl2N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472182
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-o-tolyloxy-acetic acid
Show/Hide
|
C31H26Cl2N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0493469
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,5-dimethyl-phenoxy)-acetic acid
Show/Hide
|
C32H28Cl2N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0077943
|
(2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid
Show/Hide
|
C33H39Br2N3O5
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0453219
|
2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-propylphenoxy]-2-phenylacetic acid
Show/Hide
|
C28H31N3O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0023329
|
(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C30H48N2O6
|
2
|
| 1 |
IC50 = 24900 nM
|
|
|
| 2 |
Ki = 0.46 nM
|
|
|
|
CP0395698
|
(3S)-3-[[(2S)-5-amino-2-[[(2S)-2-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-22,42-bis(2-amino-2-oxoethyl)-39-benzyl-4,7-bis(2-carboxyethyl)-10,19-bis(carboxymethyl)-13,28-bis[(1R)-1-hydroxyethyl]-45-(2-methylpropyl)-16-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecazabicyclo[23.22.4]henpentacontane-36-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-oxopentanoyl]amino]-4-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C103H147N27O37S5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0508118
|
2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-5-ethoxy-3-[4-methoxy-2-(2H-tetrazol-5-ylmethoxy)phenyl]-1,3-dihydroisoindol-2-yl]acetic acid
Show/Hide
|
C28H27N5O7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0424580
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C30H28N4O5S
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0536012
|
N-[2-[2-[(4,5-dimethyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]-N,3,3-trimethylbutanamide
Show/Hide
|
C27H30N4O5S
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0409673
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,3,3-trimethylbutanamide
Show/Hide
|
C28H32N4O5S
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0430787
|
2'-[(Methyl-phenyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C28H26N4O4S
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0465099
|
4'-Oxazol-2-yl-2'-(3-trifluoromethyl-pyrazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C25H20F3N5O4S
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0379371
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,2,2-trimethylpropanamide
Show/Hide
|
C27H30N4O5S
|
1
|
| 1 |
Ki = 0.03 nM
|
|
|
|
CP0037579
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H38N2O6
|
1
|
| 1 |
Ki = 0.034 nM
|
|
|
|
CP0453565
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,2-dimethylpropanamide
Show/Hide
|
C26H28N4O5S
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0457278
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methylbenzamide
Show/Hide
|
C29H26N4O5S
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0860692
|
2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-yl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide
Show/Hide
|
C27H28N4O5S
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0464026
|
2'-(4,4-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C27H28N4O5S
|
1
|
| 1 |
Ki = 0.045 nM
|
|
|
|
CP0402302
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-3,3,3-trifluoro-N-methylpropanamide
Show/Hide
|
C25H23F3N4O5S
|
1
|
| 1 |
Ki = 0.05 nM
|
|
|
|
CP0429972
|
N-cyclopropyl-N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-2-methylpropanamide
Show/Hide
|
C28H30N4O5S
|
1
|
| 1 |
Ki = 0.05 nM
|
|
|
|
CP0480585
|
2'-[(5-Methyl-isoxazol-3-ylamino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C25H23N5O5S
|
1
|
| 1 |
Ki = 0.07 nM
|
|
|
|
CP0374765
|
3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C22H22N2O5
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0184415
|
4-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethoxy]-3-propyl-benzoic acid
Show/Hide
|
C28H29NO8S
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0374717
|
5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
|
C25H23N9O6S
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0414951
|
4'-Oxazol-2-yl-2'-(pyrimidin-4-ylaminomethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C25H22N6O4S
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0536905
|
2'-{[Methyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C24H23F3N4O4S
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0278704
|
3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one
Show/Hide
|
C28H26O9
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0853532
|
Sodium salt (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate
Show/Hide
|
C28H25NaO9
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0414921
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methylacetamide
Show/Hide
|
C24H24N4O5S
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0457301
|
2'-Isobutoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C25H27N3O5S
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0498209
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]acetamide
Show/Hide
|
C23H22N4O5S
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0453326
|
2'-Imidazol-1-ylmethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C24H21N5O4S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0505432
|
4'-Oxazol-2-yl-2'-pyrazol-1-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C24H21N5O4S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0464427
|
2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C28H30N4O5S
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0395101
|
3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C24H24N2O5
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0393342
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-propan-2-ylacetamide
Show/Hide
|
C26H28N4O5S
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0050692
|
(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid
Show/Hide
|
C29H28O9
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0461027
|
3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-2-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Show/Hide
|
C18H15ClN2O6S2
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0460299
|
(1R,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid
Show/Hide
|
C29H28O9
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0375033
|
2-Cyclohexyl-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-acetamide
Show/Hide
|
C30H34N4O5S
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
|
CP0435987
|
3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C29H28N2O6
|
1
|
| 1 |
Ki = 0.48 nM
|
|
|
|
CP0375007
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-2-pyridin-2-ylacetamide
Show/Hide
|
C29H27N5O5S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0379025
|
N-tert-butyl-2-[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]acetamide
Show/Hide
|
C26H28N4O5S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0498064
|
2'-Isopropoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C24H25N3O5S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0448220
|
2-(4-Ethyl-6-methyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C23H24N2O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0537094
|
4'-Oxazol-2-yl-2'-oxazol-2-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C24H20N4O5S
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0404230
|
4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C23H21F3N4O4S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0449158
|
3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C23H22N2O6
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0527692
|
4'-Pyrimidin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C21H18N4O3S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0404313
|
2-(4,6-Diethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0548437
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C22H22N2O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0403956
|
2-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-N,N-dimethyl-acetamide
Show/Hide
|
C24H24N4O5S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0430810
|
4'-Oxazol-2-yl-2'-phenoxymethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C27H23N3O5S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0186021
|
(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-5-propoxy-indan-2-carboxylic acid
Show/Hide
|
C29H30O8
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0494555
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[2-(3,4,5-trimethoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
|
C32H34N2O7
|
1
|
| 1 |
Ki = 1.38 nM
|
|
|
|
CP0088035
|
4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C20H17N3O4S
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0457321
|
4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)-1,1-diphenyl-ethoxy]-ethyl}-benzoic acid
Show/Hide
|
C30H28N2O6
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0480586
|
4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C28H23N3O4S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0536129
|
3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C32H32N2O8
|
1
|
| 1 |
Ki = 1.92 nM
|
|
|
|
CP0448640
|
2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
|
C30H30N2O6
|
1
|
| 1 |
Ki = 1.95 nM
|
|
|
|
CP0392713
|
3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C30H30N2O6
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0501896
|
(S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C31H32N2O6
|
1
|
| 1 |
Ki = 2.15 nM
|
|
|
|
CP0509406
|
4'-Pyridin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C22H19N3O3S
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0380455
|
3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C31H32N2O7
|
1
|
| 1 |
Ki = 2.37 nM
|
|
|
|
CP0529647
|
4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C28H23N3O4S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0508726
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-3-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
|
C32H34N2O6
|
1
|
| 1 |
Ki = 3.13 nM
|
|
|
|
CP0449658
|
4'-Pyridin-3-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C22H19N3O3S
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0506531
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
|
C29H28N2O5
|
1
|
| 1 |
Ki = 3.48 nM
|
|
|
|
CP0373673
|
3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C31H32N2O6
|
1
|
| 1 |
Ki = 3.49 nM
|
|
|
|
CP0515048
|
4'-[1,3,4]Oxadiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C19H16N4O4S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0419227
|
4'-Thiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C20H17N3O3S2
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0449236
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C22H22N2O6
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0422899
|
N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-2,2-dimethyl-N-propan-2-ylpropanamide
Show/Hide
|
C29H34N4O5S
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0488120
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
|
C30H30N2O5
|
1
|
| 1 |
Ki = 6.03 nM
|
|
|
|
CP0498220
|
4'-Pyrazin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C21H18N4O3S
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0436707
|
4-tert-Butyl-N-[6-(3-hydroxy-propyl)-5-(2-methoxy-benzyl)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C29H33N5O4S
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0414947
|
4'-Pyrazol-1-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0461041
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C23H24N2O6
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0442023
|
2'-[(Isobutyl-methyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C26H30N4O4S
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0524206
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(3-fluoro-phenyl)-3-methoxy-propionic acid
Show/Hide
|
C22H20F2N2O6
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0451424
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-diphenyl-3-propoxy-propionic acid
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0541667
|
3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C21H20N2O4
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0464166
|
4'-(1-Methyl-1H-imidazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0441850
|
3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C29H27ClN2O4
|
1
|
| 1 |
Ki = 19.8 nM
|
|
|
|
CP0448094
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-bis-(3-methoxy-phenyl)-propionic acid
Show/Hide
|
C24H26N2O8
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0442642
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(3-p-tolyl-propoxy)-propionic acid
Show/Hide
|
C31H32N2O4
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0534924
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-di-m-tolyl-propionic acid
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0501241
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-3,3-diphenyl-propionic acid
Show/Hide
|
C29H28N2O4
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0527720
|
4'-Pyrimidin-4-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C21H18N4O3S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0404577
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-((E)-3-p-tolyl-allyloxy)-propionic acid
Show/Hide
|
C31H30N2O4
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0379136
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(2-p-tolyl-ethoxy)-propionic acid
Show/Hide
|
C30H30N2O4
|
1
|
| 1 |
Ki = 32.5 nM
|
|
|
|
CP0448090
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-fluoro-phenyl)-3-methoxy-propionic acid
Show/Hide
|
C22H20F2N2O6
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0442920
|
4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C22H19N3O4S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0510374
|
N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-(4-phenylphenyl)benzenesulfonamide
Show/Hide
|
C23H20N2O3S
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0453837
|
3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid
Show/Hide
|
C35H40N2O7
|
1
|
| 1 |
Ki = 39.3 nM
|
|
|
|
CP0404003
|
4'-(1H-Imidazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0041337
|
5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide
Show/Hide
|
C17H19N3O3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0408416
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[(E)-3-(3,4,5-trimethoxy-phenyl)-allyloxy]-propionic acid
Show/Hide
|
C33H34N2O7
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0343793
|
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H38N2O6
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0488936
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C27H24N2O6
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0454351
|
2-(4-Methoxy-5,7-dihydro-furo[3,4-d]pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-di-p-tolyl-propionic acid
Show/Hide
|
C33H34N2O7
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0409735
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-hydroxy-3,3-diphenyl-propionic acid
Show/Hide
|
C21H20N2O6
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0542886
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(2-fluoro-phenyl)-3-methoxy-propionic acid
Show/Hide
|
C22H20F2N2O6
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0497687
|
3,3-Bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
|
C34H38N2O6
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0488937
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-methylsulfanyl-phenoxy)-3-phenyl-butyric acid methyl ester
Show/Hide
|
C24H26N2O6S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0510711
|
2-(4,6-Diethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 174 nM
|
|
|
|
CP0407272
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-di-p-tolyl-propionic acid
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0430401
|
4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C23H22N4O5S
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0403590
|
3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid
Show/Hide
|
C31H30Cl2N2O7
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0377933
|
3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-propionic acid
Show/Hide
|
C22H20Cl2N2O6
|
1
|
| 1 |
Ki = 245 nM
|
|
|
|
CP0448422
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl-phenoxy)-3-phenyl-butyric acid methyl ester
Show/Hide
|
C26H30N2O6
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0393642
|
2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-bis-(4-ethyl-phenyl)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
|
C34H38N2O5
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0537792
|
4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C20H17N3O4S
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0409668
|
3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-propionic acid
Show/Hide
|
C33H32Cl2N2O7
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0393338
|
4'-Pyrimidin-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C21H18N4O3S
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0460511
|
2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(3,3-dimethyl-butoxy)-3,3-diphenyl-propionic acid
Show/Hide
|
C27H32N2O6
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0439329
|
4'-(1H-Tetrazol-5-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
|
C18H16N6O3S
|
1
|
| 1 |
Ki = 3800 nM
|
|
|
