Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-propionic acid
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 PubChem ID
CID: 10508342
SID: 15533292
Canonical SMILES
COc1ccc(CCOC(C(Oc2nc3CCCc3c(OC)n2)C(O)=O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1OC
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Compound Formula C33H32Cl2N2O7
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 290 nM
   TI
   LI
   LO
   TS