Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-amide
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 PubChem ID
CID: 44385805
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1cnccn1
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Compound Formula C26H24N6O5S
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 339 nM
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